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The map label for this gene is hdrC [H]

Identifier: 78356160

GI number: 78356160

Start: 1141971

End: 1143125

Strand: Direct

Name: hdrC [H]

Synonym: Dde_1113

Alternate gene names: 78356160

Gene position: 1141971-1143125 (Clockwise)

Preceding gene: 78356159

Following gene: 78356161

Centisome position: 30.61

GC content: 55.76

Gene sequence:

>1155_bases
ATGGCTCAGCCTGTACGTATCGAACCAGATCTGCAGTTTGTGAAGGAGTTGCAAGCTGTCGGTGGAGAGTCGCTGAAAAA
GTGCTATCAGTGCGCCACCTGCAGTGTGGCGTGCCCCATCTCCCCCGCCAGCAATCCCTACCCCCGCAAGGAGATGGTGT
GGGCATCGTGGGGTATGCGCGACAAGCTGCTCAACAATGTGGATATCTGGCTTTGTCACAACTGCGGCACCTGCTCCGAC
CTGTGCCCCCGCGGTGCAAAGCCCGGTGACCTGCTGGCGGCTTTGCGCAACATGGCCTATCAGCGCCTTACAAAGCCATC
CATTGTCGGTAAATGGATGAGCTCGCCCAAGTATCTGCCTATTCTGTTCGGCATTCCGGCCGTGCTGTGGGCAGTGGTCT
GGATGATCATGGCCAGCGTGAACGGTACTGTGATTCCCGAAGGCACCATCGTTTTCGGAAAGCTGTTCCCCGGCGATTTC
ACCATAGACCCCATCTTTATTGTTACGTTCTTCAGTATGGTGGGCATATTCTGGAAAGGCACAAGAAATCTGATTGCTTC
GTTTAAACCGGAAGGCAAAACGCTGGTGCTGGGCAAAACCAAGCACTGGATTCTGCATCTGGTGGACGTGCTCAGAGAAG
AGATTCTGACCCATTCCAAGTTCAAGGACTGCGGTGACGACCGTTCCGACCGCAAGGTGGGACACATGGCTGTATTCTAC
AGCTTCATCATTCTGATGATCGTCACCGCCATTGTGGCCGCAGGACACTGGGGCGGAAAGGTCATTCCGGCCATTGCGCT
GCATACCCCCATGCCGCTGCTGTTCCCTGTGAAAATTCTGGCCAACATCGGCGCCATTATGCTGGTTGTGGGGCTGGCTA
TTCTCACACACCGCCGCCGTCAGCAGGATCCTGAGAAGACCAGATCGAACTACTACGACTGGTATCTGCTCAATGTGATC
TGGTTTGTCACGCTGACCGGTATCGGAGCACAGCTGTTCCGTCTGGCTGATATCGCTCCCGTGGCCTACTTCGTCTACTA
CCTGCACCTTGTGTCTGTGTGGATGCTGTTCGCATACCTGCCCTGGTCCAAGCTGGGCCACCTGGTGTACCGTACAGCCG
CACTTACCTACGTGCGGATGATGGGCCGTCGCTAG

Upstream 100 bases:

>100_bases
GACGAATACGACAAGCTGCCCGGCATGATCGACGAGTTCATGAACATGATCCTTGAAAAGGGCCCCAACCCGTTCAAGGG
TTACTAGGAGGAGATGGAAG

Downstream 100 bases:

>100_bases
TCACGTAACGGGGTGCCTTTGGGCGCCCCGATAAAGAACGATAAAACTTTTCCTTGAAATAGGAGGCAGAAATGTCTGAC
GAAGCTCGCAGAGTATTTAA

Product: heterodisulfide reductase, transmembrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MAQPVRIEPDLQFVKELQAVGGESLKKCYQCATCSVACPISPASNPYPRKEMVWASWGMRDKLLNNVDIWLCHNCGTCSD
LCPRGAKPGDLLAALRNMAYQRLTKPSIVGKWMSSPKYLPILFGIPAVLWAVVWMIMASVNGTVIPEGTIVFGKLFPGDF
TIDPIFIVTFFSMVGIFWKGTRNLIASFKPEGKTLVLGKTKHWILHLVDVLREEILTHSKFKDCGDDRSDRKVGHMAVFY
SFIILMIVTAIVAAGHWGGKVIPAIALHTPMPLLFPVKILANIGAIMLVVGLAILTHRRRQQDPEKTRSNYYDWYLLNVI
WFVTLTGIGAQLFRLADIAPVAYFVYYLHLVSVWMLFAYLPWSKLGHLVYRTAALTYVRMMGRR

Sequences:

>Translated_384_residues
MAQPVRIEPDLQFVKELQAVGGESLKKCYQCATCSVACPISPASNPYPRKEMVWASWGMRDKLLNNVDIWLCHNCGTCSD
LCPRGAKPGDLLAALRNMAYQRLTKPSIVGKWMSSPKYLPILFGIPAVLWAVVWMIMASVNGTVIPEGTIVFGKLFPGDF
TIDPIFIVTFFSMVGIFWKGTRNLIASFKPEGKTLVLGKTKHWILHLVDVLREEILTHSKFKDCGDDRSDRKVGHMAVFY
SFIILMIVTAIVAAGHWGGKVIPAIALHTPMPLLFPVKILANIGAIMLVVGLAILTHRRRQQDPEKTRSNYYDWYLLNVI
WFVTLTGIGAQLFRLADIAPVAYFVYYLHLVSVWMLFAYLPWSKLGHLVYRTAALTYVRMMGRR
>Mature_383_residues
AQPVRIEPDLQFVKELQAVGGESLKKCYQCATCSVACPISPASNPYPRKEMVWASWGMRDKLLNNVDIWLCHNCGTCSDL
CPRGAKPGDLLAALRNMAYQRLTKPSIVGKWMSSPKYLPILFGIPAVLWAVVWMIMASVNGTVIPEGTIVFGKLFPGDFT
IDPIFIVTFFSMVGIFWKGTRNLIASFKPEGKTLVLGKTKHWILHLVDVLREEILTHSKFKDCGDDRSDRKVGHMAVFYS
FIILMIVTAIVAAGHWGGKVIPAIALHTPMPLLFPVKILANIGAIMLVVGLAILTHRRRQQDPEKTRSNYYDWYLLNVIW
FVTLTGIGAQLFRLADIAPVAYFVYYLHLVSVWMLFAYLPWSKLGHLVYRTAALTYVRMMGRR

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrC may carry electrons from hydrogenase to hdrA [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Loosely Bound To The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017680
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 43282; Mature: 43151

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPVRIEPDLQFVKELQAVGGESLKKCYQCATCSVACPISPASNPYPRKEMVWASWGMR
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCCCCCCCHHHEEHHCCCH
DKLLNNVDIWLCHNCGTCSDLCPRGAKPGDLLAALRNMAYQRLTKPSIVGKWMSSPKYLP
HHHHCCCCEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCH
ILFGIPAVLWAVVWMIMASVNGTVIPEGTIVFGKLFPGDFTIDPIFIVTFFSMVGIFWKG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
TRNLIASFKPEGKTLVLGKTKHWILHLVDVLREEILTHSKFKDCGDDRSDRKVGHMAVFY
HHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
SFIILMIVTAIVAAGHWGGKVIPAIALHTPMPLLFPVKILANIGAIMLVVGLAILTHRRR
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQDPEKTRSNYYDWYLLNVIWFVTLTGIGAQLFRLADIAPVAYFVYYLHLVSVWMLFAYL
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PWSKLGHLVYRTAALTYVRMMGRR
CHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQPVRIEPDLQFVKELQAVGGESLKKCYQCATCSVACPISPASNPYPRKEMVWASWGMR
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCCCCCCCHHHEEHHCCCH
DKLLNNVDIWLCHNCGTCSDLCPRGAKPGDLLAALRNMAYQRLTKPSIVGKWMSSPKYLP
HHHHCCCCEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCH
ILFGIPAVLWAVVWMIMASVNGTVIPEGTIVFGKLFPGDFTIDPIFIVTFFSMVGIFWKG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
TRNLIASFKPEGKTLVLGKTKHWILHLVDVLREEILTHSKFKDCGDDRSDRKVGHMAVFY
HHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
SFIILMIVTAIVAAGHWGGKVIPAIALHTPMPLLFPVKILANIGAIMLVVGLAILTHRRR
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQDPEKTRSNYYDWYLLNVIWFVTLTGIGAQLFRLADIAPVAYFVYYLHLVSVWMLFAYL
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PWSKLGHLVYRTAALTYVRMMGRR
CHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]