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The map label for this gene is hrcA [H]

Identifier: 78356073

GI number: 78356073

Start: 1050835

End: 1051899

Strand: Reverse

Name: hrcA [H]

Synonym: Dde_1026

Alternate gene names: 78356073

Gene position: 1051899-1050835 (Counterclockwise)

Preceding gene: 78356074

Following gene: 78356072

Centisome position: 28.2

GC content: 59.34

Gene sequence:

>1065_bases
ATGAATCTGGCACACAGAGAGGCCGAAATTCTGGCCACCATCATAGAGCGCTACATCGCCACGGCCGCCCCTGTGGGGTC
TGTTTCCGTGGCCAGACGCTCCGGCCTGCGGCTTTCCGCCGCCAGCATGCGCAATACCATGGCCGAACTGACTGACAAGG
GGTATCTTTCGCAGCCGCATGCCTCGGCGGGACGCATTCCCACAGCGCGCGGGTTCCGGCTGTATCTTGACGCACTGCTC
AAAACGCGGCCCCTTTCCCGCGACGAGCGTTCAGCCATTCTCAACGAACTGACAACCCACGGACTGGAAATATCCGACAT
GCTGCGCGAGGCTTCGCGCATGCTTTCGGCACACTCACGTCAGGTGGCCGTTGTGCTGGCCCCCAGCAGAGACGAAGTGC
GCTGGCATACCATTGATTTTGTTAAAATCAGTGACACGCTGGTGCTCACCGTACTGGTACTGGAAGGCGGGCTGGTGCGC
AATCATGTGCTGAGCGTGGAAACACCGGTAACGCAGGACGAACTGGTACGCTACGGCAACTACCTGAATGAATACTGTAA
AGGGCTTACGCTGTCTCAGGCACGGGTGCGTGTGGCGCGCGAACTGCAGGCGGCGGAAGCGCATCTTGAAGCGCTGTATT
TCCGCGCTCTCGGACTGGCCCGACTGGCTTTCGAGCATATGGACGACGACCGCGAGGTCTTTGTCAACGGTACGCTGAAC
ATGCTTGATCAGGCGGAATTTACAGACCATACCCGCATACGCGACATGCTGGCGCTGCTTGAAGAACGCAACAGCATTCT
GGAACTGCTGGACAAAGCCATTCTGAGCGATTCGGTGACGGTCAGCTTCGGGCAGGAAGACGAAAACGAAGGCACCGCGC
CTCTGGGGTGCAGCGTGGTTTCCGCCCCGTACGGGGGACTGCAGCAGGCCTCTCCCGCAGGGGTTGTCAGCGTGCTGGGC
CCGCTGCGCATGAACTACCGGCAGGTACTGCCGGTGGTTGACTGTATCTCAAAGACCCTTACTACATTGTTGCAGGACAG
GTTCGGCACCGAACATTCGGACTGA

Upstream 100 bases:

>100_bases
ACCGCTTCAGGCAGTCATAAGACAACCTTCCGGGCTGTCTGCATGATGCGGACGGCGCTGCCGGCCTGTCATCCATGGCC
CTGCTCCACGGGAGAAACGC

Downstream 100 bases:

>100_bases
GCCGCAGCTACCCTGCTGTTCTGAAACGTGCCCGCTCCGGCGGGGGCGTTCTGTACGCGCATCATGACGGCTATGCCGAT
GTTTTGAATATAAAGGAGAT

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNLAHREAEILATIIERYIATAAPVGSVSVARRSGLRLSAASMRNTMAELTDKGYLSQPHASAGRIPTARGFRLYLDALL
KTRPLSRDERSAILNELTTHGLEISDMLREASRMLSAHSRQVAVVLAPSRDEVRWHTIDFVKISDTLVLTVLVLEGGLVR
NHVLSVETPVTQDELVRYGNYLNEYCKGLTLSQARVRVARELQAAEAHLEALYFRALGLARLAFEHMDDDREVFVNGTLN
MLDQAEFTDHTRIRDMLALLEERNSILELLDKAILSDSVTVSFGQEDENEGTAPLGCSVVSAPYGGLQQASPAGVVSVLG
PLRMNYRQVLPVVDCISKTLTTLLQDRFGTEHSD

Sequences:

>Translated_354_residues
MNLAHREAEILATIIERYIATAAPVGSVSVARRSGLRLSAASMRNTMAELTDKGYLSQPHASAGRIPTARGFRLYLDALL
KTRPLSRDERSAILNELTTHGLEISDMLREASRMLSAHSRQVAVVLAPSRDEVRWHTIDFVKISDTLVLTVLVLEGGLVR
NHVLSVETPVTQDELVRYGNYLNEYCKGLTLSQARVRVARELQAAEAHLEALYFRALGLARLAFEHMDDDREVFVNGTLN
MLDQAEFTDHTRIRDMLALLEERNSILELLDKAILSDSVTVSFGQEDENEGTAPLGCSVVSAPYGGLQQASPAGVVSVLG
PLRMNYRQVLPVVDCISKTLTTLLQDRFGTEHSD
>Mature_354_residues
MNLAHREAEILATIIERYIATAAPVGSVSVARRSGLRLSAASMRNTMAELTDKGYLSQPHASAGRIPTARGFRLYLDALL
KTRPLSRDERSAILNELTTHGLEISDMLREASRMLSAHSRQVAVVLAPSRDEVRWHTIDFVKISDTLVLTVLVLEGGLVR
NHVLSVETPVTQDELVRYGNYLNEYCKGLTLSQARVRVARELQAAEAHLEALYFRALGLARLAFEHMDDDREVFVNGTLN
MLDQAEFTDHTRIRDMLALLEERNSILELLDKAILSDSVTVSFGQEDENEGTAPLGCSVVSAPYGGLQQASPAGVVSVLG
PLRMNYRQVLPVVDCISKTLTTLLQDRFGTEHSD

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39123; Mature: 39123

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAHREAEILATIIERYIATAAPVGSVSVARRSGLRLSAASMRNTMAELTDKGYLSQPH
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCC
ASAGRIPTARGFRLYLDALLKTRPLSRDERSAILNELTTHGLEISDMLREASRMLSAHSR
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
QVAVVLAPSRDEVRWHTIDFVKISDTLVLTVLVLEGGLVRNHVLSVETPVTQDELVRYGN
EEEEEEECCCCCCEEEEEEEEEECHHHHHHHHHHHCCHHHHHEEECCCCCCHHHHHHHHH
YLNEYCKGLTLSQARVRVARELQAAEAHLEALYFRALGLARLAFEHMDDDREVFVNGTLN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
MLDQAEFTDHTRIRDMLALLEERNSILELLDKAILSDSVTVSFGQEDENEGTAPLGCSVV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHH
SAPYGGLQQASPAGVVSVLGPLRMNYRQVLPVVDCISKTLTTLLQDRFGTEHSD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNLAHREAEILATIIERYIATAAPVGSVSVARRSGLRLSAASMRNTMAELTDKGYLSQPH
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCC
ASAGRIPTARGFRLYLDALLKTRPLSRDERSAILNELTTHGLEISDMLREASRMLSAHSR
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
QVAVVLAPSRDEVRWHTIDFVKISDTLVLTVLVLEGGLVRNHVLSVETPVTQDELVRYGN
EEEEEEECCCCCCEEEEEEEEEECHHHHHHHHHHHCCHHHHHEEECCCCCCHHHHHHHHH
YLNEYCKGLTLSQARVRVARELQAAEAHLEALYFRALGLARLAFEHMDDDREVFVNGTLN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
MLDQAEFTDHTRIRDMLALLEERNSILELLDKAILSDSVTVSFGQEDENEGTAPLGCSVV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHH
SAPYGGLQQASPAGVVSVLGPLRMNYRQVLPVVDCISKTLTTLLQDRFGTEHSD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA