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The map label for this gene is mrdB [H]

Identifier: 78356039

GI number: 78356039

Start: 1016995

End: 1018110

Strand: Reverse

Name: mrdB [H]

Synonym: Dde_0992

Alternate gene names: 78356039

Gene position: 1018110-1016995 (Counterclockwise)

Preceding gene: 78356040

Following gene: 78356038

Centisome position: 27.29

GC content: 56.0

Gene sequence:

>1116_bases
ATGAGCCCCATAGACAGACGCATTCTGACTCATATGAACTGGGGGCTCATCGCCATGACGCTGCTGCTTTTCGGCGTGGG
CGTGGCCAACCTGTATTCGGCATCGGGGTTCCGCGTGGACGACGGCATCGCTGTCTCCTCATTCTACAGCAAACAGCTTC
TGTGGGGGGCTGTGGGCATGGGCGGCATGCTGGCCGTCATGCTTTTCGACTACCGCCACCTTAAAAGTCTGGCGTGGCCT
GTATTCATTGTCACAGTGCTGCTGCTGGTGGCCGTTCCGCTTTTCGGCGTAACGGTTTACGGCGCCAAGCGCTGGCTTTC
CTTTGGTTTTTTCAACCTGCAGCCCAGCGAACTGGCAAAAATCAGCACGCTGATCATCGCCGCAAGACTGCTTTCCCGCG
GGGGCGAACCGCTGGACTGGGGTGAACTTTTCAAAATACTGGGTATATGCCTTATTCCGGCCGCCCTCATTGTCACCCAG
CCGGACCTCGGCACCACCCTCAACGTGCTGCTCAACGTGGGCGGAGTCATACTGTACCGCGGCATTGCGCGGCATGTTTT
CAAAACCTGCATCATCGCCCTGCCTCCGCTCATTCCGCTGGGCTGGTTTGTGCTGCACGACTATCAGAAACAGCGCATAC
TCACATTTCTCGATCCCGGACGCGATCCGCTGGGAGCCGGTTACCACATCATCCAGTCGCAGATAGCCATCGGTTCCGGA
CAGATATGGGGCAAGGGTTTTCTGGGCGGCACCCAGTCACAATTGCGCTTTCTGCCCGAAAAGCATACAGACTTTGCTGT
GGCGGTTTTCGGCGAAGAGTGGGGATTCATCGGCAACATGATTCTGCTGGGTCTGTTCTGCCTGTTCCTGCTGGCCATAT
TCAACTCCGCCCGCGATGCAAAAGACCGTTTCGGCAGCTTTCTGTGCGCCGGCGTGTTTTTTTATTTTTTCTGGCAAATT
CTTATAAATATGGGCATGGTGGTCGGGCTGATGCCTGTGGTGGGTATCCCCCTGCCTTTCATCAGCTACGGCGGCAGCGC
CACTATCGTCAATTTCTGCCTGATAGGTCTGGTGCTGAACGTCTCCATGCGCCGCTTTGTCTTTAAAGCATCATGA

Upstream 100 bases:

>100_bases
TGGAACACGGCGGCGGTGGCAGCAGCACCGCAGGCCCCATTGTGAAAGGACTTTTCGACTACCTCTTCGGCGTGCCCGGA
GAAGCGGGAGCTGACAGCCA

Downstream 100 bases:

>100_bases
GCCGCATCATGAAAAGGGCTGCTGAACATGCCTCTTTTTTCGCGATCCAGTAAGGAGCATGCACGAATGTCGAAAGATGA
AATCAACGCCTTTTTGGGCG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSPIDRRILTHMNWGLIAMTLLLFGVGVANLYSASGFRVDDGIAVSSFYSKQLLWGAVGMGGMLAVMLFDYRHLKSLAWP
VFIVTVLLLVAVPLFGVTVYGAKRWLSFGFFNLQPSELAKISTLIIAARLLSRGGEPLDWGELFKILGICLIPAALIVTQ
PDLGTTLNVLLNVGGVILYRGIARHVFKTCIIALPPLIPLGWFVLHDYQKQRILTFLDPGRDPLGAGYHIIQSQIAIGSG
QIWGKGFLGGTQSQLRFLPEKHTDFAVAVFGEEWGFIGNMILLGLFCLFLLAIFNSARDAKDRFGSFLCAGVFFYFFWQI
LINMGMVVGLMPVVGIPLPFISYGGSATIVNFCLIGLVLNVSMRRFVFKAS

Sequences:

>Translated_371_residues
MSPIDRRILTHMNWGLIAMTLLLFGVGVANLYSASGFRVDDGIAVSSFYSKQLLWGAVGMGGMLAVMLFDYRHLKSLAWP
VFIVTVLLLVAVPLFGVTVYGAKRWLSFGFFNLQPSELAKISTLIIAARLLSRGGEPLDWGELFKILGICLIPAALIVTQ
PDLGTTLNVLLNVGGVILYRGIARHVFKTCIIALPPLIPLGWFVLHDYQKQRILTFLDPGRDPLGAGYHIIQSQIAIGSG
QIWGKGFLGGTQSQLRFLPEKHTDFAVAVFGEEWGFIGNMILLGLFCLFLLAIFNSARDAKDRFGSFLCAGVFFYFFWQI
LINMGMVVGLMPVVGIPLPFISYGGSATIVNFCLIGLVLNVSMRRFVFKAS
>Mature_370_residues
SPIDRRILTHMNWGLIAMTLLLFGVGVANLYSASGFRVDDGIAVSSFYSKQLLWGAVGMGGMLAVMLFDYRHLKSLAWPV
FIVTVLLLVAVPLFGVTVYGAKRWLSFGFFNLQPSELAKISTLIIAARLLSRGGEPLDWGELFKILGICLIPAALIVTQP
DLGTTLNVLLNVGGVILYRGIARHVFKTCIIALPPLIPLGWFVLHDYQKQRILTFLDPGRDPLGAGYHIIQSQIAIGSGQ
IWGKGFLGGTQSQLRFLPEKHTDFAVAVFGEEWGFIGNMILLGLFCLFLLAIFNSARDAKDRFGSFLCAGVFFYFFWQIL
INMGMVVGLMPVVGIPLPFISYGGSATIVNFCLIGLVLNVSMRRFVFKAS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=319, Percent_Identity=42.0062695924765, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1786277, Length=300, Percent_Identity=34.6666666666667, Blast_Score=157, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40795; Mature: 40664

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCC
>Mature Secondary Structure 
SPIDRRILTHMNWGLIAMTLLLFGVGVANLYSASGFRVDDGIAVSSFYSKQLLWGAVGM
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCH
GGMLAVMLFDYRHLKSLAWPVFIVTVLLLVAVPLFGVTVYGAKRWLSFGFFNLQPSELAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ISTLIIAARLLSRGGEPLDWGELFKILGICLIPAALIVTQPDLGTTLNVLLNVGGVILYR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GIARHVFKTCIIALPPLIPLGWFVLHDYQKQRILTFLDPGRDPLGAGYHIIQSQIAIGSG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
QIWGKGFLGGTQSQLRFLPEKHTDFAVAVFGEEWGFIGNMILLGLFCLFLLAIFNSARDA
CCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
KDRFGSFLCAGVFFYFFWQILINMGMVVGLMPVVGIPLPFISYGGSATIVNFCLIGLVLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHH
VSMRRFVFKAS
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]