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The map label for this gene is atpA

Identifier: 78356034

GI number: 78356034

Start: 1013296

End: 1014804

Strand: Reverse

Name: atpA

Synonym: Dde_0987

Alternate gene names: 78356034

Gene position: 1014804-1013296 (Counterclockwise)

Preceding gene: 78356035

Following gene: 78356033

Centisome position: 27.2

GC content: 57.65

Gene sequence:

>1509_bases
ATGCAGATTAAGACCGAAGAAATCAGCCAGATCATCGAATCGCAGATTCAGAATTACGAACAGCGAGTCGAGATGAGCGA
AACCGGTACCGTGCTTTACGTCGGTGACGGTATTGCACGCGTTTACGGTGTTCGCAACGCCATGGCCATGGAACTGCTGG
AATTTCCCGGCGGGCTCATGGGTATGGTGCTGAACCTTGAAGAAGACAACGTCGGTGTGGCCCTGCTGGGTCCGGATACC
GACATTAAAGAAGGTGACCCGGTAAAGCGTACCGGCAAAATCTTCTCCGTGCCGGTGGGCGATGCGGTCATGGGCCGTGT
TCTCAACCCCCTCGGCCAGCCCATTGACGGCGAAGGACCGGTTGACTCCAAAGAATTCCGTCCTGTTGAACTTAAGGCTC
CCGGCATCATCGCCCGTAAGTCCGTGCACGAACCCATGCCCACCGGCATCAAGGCTATCGACGCCATGACGCCCATCGGC
CGCGGTCAGCGCGAACTTGTCATCGGCGACCGTCAGACCGGTAAGACCGCCGTCTGCATCGACGCCATTCTGGCGCAGAA
AAACACCGACATCCACTGCTTCTACGTGGCCATCGGTCAGAAGCGTTCCACTGTTGCTCTGGTGGCAGACACGCTGAAAA
AACACGGCGCGATGGAATACACCACCATCATCTCCGCCACCGCTTCCGAACCGGCTCCGCTTCAGTTCATCGCCGCCTAT
GCCGGCTGTGCCATGGCTGAATACTACCGCGACAGCGGCAAGCATGCGCTCATCGTTTACGATGACCTTTCCAAGCAGGC
TACCGCCTACCGCCAGATGTCGCTGCTGCTGCGCCGTCCTCCCGGACGTGAAGCTTTCCCCGGCGACGTTTTCTACCTGC
ACTCGCGGCTGCTTGAACGTGCCGCAAAAGTGAACGACAGCCTGGGTGCCGGTTCGCTTACCGCCCTGCCCATCATTGAA
ACGCAGGCCGGTGACGTTTCCGCCTACATCCCGACCAACGTTATCTCCATTACCGACGGTCAGGTGTACCTCGAACCCAA
CCTGTTCAACGCCGGTATCCGTCCTGCCATCAACGTCGGTCTGTCAGTTTCCCGAGTGGGCGGCGCTGCACAGATCAAGG
CAATGAAGCAGGTTGCAGGTACCATGCGTCTTGACCTTGCCCAGTACCGCGAACTGGCAGCTTTTGCCCAGTTCGGTTCT
GACCTTGACAAGGCAACGCAGGCAAAGCTGAACCGTGGCGCACGCCTGGTCGAACTGCTCAAGCAGCCCCAGTACCAGCC
CATGCCGTTCAACGAGCAGGTAGCTTCCATGTACGCGGCAACCCGTGGCTTCATGGACGATGTGCCTGTGGCATCCATCC
GCAAGTTCGAAGCTGAGTACATTGAGTTCCTGCGGGACGCCAAGGGTGACATACTGAAAGATCTTGACGAGAAAAAGGCC
ATTGACAACGACATCGAAGGACGCATGAAAGCGGCTCTCGAAGAGTTCAAAAAAGGCTTCACCGCCTAA

Upstream 100 bases:

>100_bases
GGCGGCGTCGTGCTGAAGGTCGGCGACCGTGTTCTTGATGCCAGCCTGCGCGCACAGCTGGGCATTCTGAAGGATAACAT
CAAGAGGGGTGAGTAGGGCC

Downstream 100 bases:

>100_bases
CCGCGGGGGGTAATATGCCTTCTTTGAAAGATGTCCAACTGAAAATCGCCGGTGTGAAGAAGACAAAACAGATCACCAAA
GCGATGAACATGGTGGCCTC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MQIKTEEISQIIESQIQNYEQRVEMSETGTVLYVGDGIARVYGVRNAMAMELLEFPGGLMGMVLNLEEDNVGVALLGPDT
DIKEGDPVKRTGKIFSVPVGDAVMGRVLNPLGQPIDGEGPVDSKEFRPVELKAPGIIARKSVHEPMPTGIKAIDAMTPIG
RGQRELVIGDRQTGKTAVCIDAILAQKNTDIHCFYVAIGQKRSTVALVADTLKKHGAMEYTTIISATASEPAPLQFIAAY
AGCAMAEYYRDSGKHALIVYDDLSKQATAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKVNDSLGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQVYLEPNLFNAGIRPAINVGLSVSRVGGAAQIKAMKQVAGTMRLDLAQYRELAAFAQFGS
DLDKATQAKLNRGARLVELLKQPQYQPMPFNEQVASMYAATRGFMDDVPVASIRKFEAEYIEFLRDAKGDILKDLDEKKA
IDNDIEGRMKAALEEFKKGFTA

Sequences:

>Translated_502_residues
MQIKTEEISQIIESQIQNYEQRVEMSETGTVLYVGDGIARVYGVRNAMAMELLEFPGGLMGMVLNLEEDNVGVALLGPDT
DIKEGDPVKRTGKIFSVPVGDAVMGRVLNPLGQPIDGEGPVDSKEFRPVELKAPGIIARKSVHEPMPTGIKAIDAMTPIG
RGQRELVIGDRQTGKTAVCIDAILAQKNTDIHCFYVAIGQKRSTVALVADTLKKHGAMEYTTIISATASEPAPLQFIAAY
AGCAMAEYYRDSGKHALIVYDDLSKQATAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKVNDSLGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQVYLEPNLFNAGIRPAINVGLSVSRVGGAAQIKAMKQVAGTMRLDLAQYRELAAFAQFGS
DLDKATQAKLNRGARLVELLKQPQYQPMPFNEQVASMYAATRGFMDDVPVASIRKFEAEYIEFLRDAKGDILKDLDEKKA
IDNDIEGRMKAALEEFKKGFTA
>Mature_502_residues
MQIKTEEISQIIESQIQNYEQRVEMSETGTVLYVGDGIARVYGVRNAMAMELLEFPGGLMGMVLNLEEDNVGVALLGPDT
DIKEGDPVKRTGKIFSVPVGDAVMGRVLNPLGQPIDGEGPVDSKEFRPVELKAPGIIARKSVHEPMPTGIKAIDAMTPIG
RGQRELVIGDRQTGKTAVCIDAILAQKNTDIHCFYVAIGQKRSTVALVADTLKKHGAMEYTTIISATASEPAPLQFIAAY
AGCAMAEYYRDSGKHALIVYDDLSKQATAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKVNDSLGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQVYLEPNLFNAGIRPAINVGLSVSRVGGAAQIKAMKQVAGTMRLDLAQYRELAAFAQFGS
DLDKATQAKLNRGARLVELLKQPQYQPMPFNEQVASMYAATRGFMDDVPVASIRKFEAEYIEFLRDAKGDILKDLDEKKA
IDNDIEGRMKAALEEFKKGFTA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=506, Percent_Identity=62.4505928853755, Blast_Score=638, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=506, Percent_Identity=62.4505928853755, Blast_Score=638, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=293, Percent_Identity=29.3515358361775, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI19913426, Length=293, Percent_Identity=29.3515358361775, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI32189394, Length=350, Percent_Identity=24.8571428571429, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI19913424, Length=418, Percent_Identity=24.6411483253589, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790172, Length=508, Percent_Identity=55.5118110236221, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1788251, Length=320, Percent_Identity=28.125, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790170, Length=427, Percent_Identity=24.824355971897, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=62.1513944223108, Blast_Score=644, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=62.1513944223108, Blast_Score=642, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=58.1673306772908, Blast_Score=587, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17510931, Length=371, Percent_Identity=27.7628032345013, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=322, Percent_Identity=28.2608695652174, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=370, Percent_Identity=24.3243243243243, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=50.6849315068493, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=256, Percent_Identity=25.390625, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=58.3665338645418, Blast_Score=614, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319603, Length=335, Percent_Identity=28.0597014925373, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=406, Percent_Identity=25.3694581280788, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=159, Percent_Identity=30.8176100628931, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=61.7821782178218, Blast_Score=632, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=294, Percent_Identity=28.9115646258503, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646341, Length=294, Percent_Identity=28.9115646258503, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136796, Length=294, Percent_Identity=28.9115646258503, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24638766, Length=406, Percent_Identity=24.384236453202, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28574560, Length=380, Percent_Identity=26.3157894736842, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20129479, Length=258, Percent_Identity=27.1317829457364, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=25.4901960784314, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_DESDG (Q313V8)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387483.1
- ProteinModelPortal:   Q313V8
- SMR:   Q313V8
- STRING:   Q313V8
- GeneID:   3755559
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_0987
- NMPDR:   fig|207559.3.peg.489
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- ProtClustDB:   PRK09281
- BioCyc:   DDES207559:DDE_0987-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54667; Mature: 54667

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKTEEISQIIESQIQNYEQRVEMSETGTVLYVGDGIARVYGVRNAMAMELLEFPGGLM
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCE
GMVLNLEEDNVGVALLGPDTDIKEGDPVKRTGKIFSVPVGDAVMGRVLNPLGQPIDGEGP
EEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
VDSKEFRPVELKAPGIIARKSVHEPMPTGIKAIDAMTPIGRGQRELVIGDRQTGKTAVCI
CCCCCCCEEEECCCCEEHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
DAILAQKNTDIHCFYVAIGQKRSTVALVADTLKKHGAMEYTTIISATASEPAPLQFIAAY
HHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEHEEEECCCCCCCHHHHHHH
AGCAMAEYYRDSGKHALIVYDDLSKQATAYRQMSLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKVNDSLGAGSLTALPIIETQAGDVSAYIPTNVISITDGQVYLEPNLFNAGIRPAINVG
HHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEECCCCCCCCCCHHHHCC
LSVSRVGGAAQIKAMKQVAGTMRLDLAQYRELAAFAQFGSDLDKATQAKLNRGARLVELL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHH
KQPQYQPMPFNEQVASMYAATRGFMDDVPVASIRKFEAEYIEFLRDAKGDILKDLDEKKA
HCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IDNDIEGRMKAALEEFKKGFTA
CCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQIKTEEISQIIESQIQNYEQRVEMSETGTVLYVGDGIARVYGVRNAMAMELLEFPGGLM
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCE
GMVLNLEEDNVGVALLGPDTDIKEGDPVKRTGKIFSVPVGDAVMGRVLNPLGQPIDGEGP
EEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
VDSKEFRPVELKAPGIIARKSVHEPMPTGIKAIDAMTPIGRGQRELVIGDRQTGKTAVCI
CCCCCCCEEEECCCCEEHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
DAILAQKNTDIHCFYVAIGQKRSTVALVADTLKKHGAMEYTTIISATASEPAPLQFIAAY
HHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEHEEEECCCCCCCHHHHHHH
AGCAMAEYYRDSGKHALIVYDDLSKQATAYRQMSLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKVNDSLGAGSLTALPIIETQAGDVSAYIPTNVISITDGQVYLEPNLFNAGIRPAINVG
HHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEECCCCCCCCCCHHHHCC
LSVSRVGGAAQIKAMKQVAGTMRLDLAQYRELAAFAQFGSDLDKATQAKLNRGARLVELL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHH
KQPQYQPMPFNEQVASMYAATRGFMDDVPVASIRKFEAEYIEFLRDAKGDILKDLDEKKA
HCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IDNDIEGRMKAALEEFKKGFTA
CCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA