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The map label for this gene is atpH

Identifier: 78356035

GI number: 78356035

Start: 1014809

End: 1015360

Strand: Reverse

Name: atpH

Synonym: Dde_0988

Alternate gene names: 78356035

Gene position: 1015360-1014809 (Counterclockwise)

Preceding gene: 78356036

Following gene: 78356034

Centisome position: 27.22

GC content: 56.88

Gene sequence:

>552_bases
TTGACCGGCAACATCGCAGCTCGTAGGTATGCAAGGGCGCTTTTTGCCATAGGGCAGAAGCAGGGGCTTGCCGAACTCGA
TGCTTTCGGTTCCGAGCTCTCCGCCGTTGCTAAGGCCGTGGAGGAATCTCCCGCGCTTGCCAGACTCTTCCGCAACCCGC
TCTTCAGCATTGAAGAGAAGCGTGCGGTTCTGGCCAAGCTTTTACAAGCCGCCGGGGCAGGCCAGACTGTCAGCAACTTC
TGCAACCTGCTTGCAGACAAAGGCAGACTGGCAGACCTGCCGGACATCAACGCGTTTTACAGTCTTCTGCTTGATGCCGA
AAAAGGCATCATCCGCGGCGAGCTGGTTACCGCCATCAAACTGGCCAAGGCCAAGCGTGATGCGGTGAAAGAACAGCTTG
AAAAGCAGGCCGGACAGAAGATTGAGCTGAACTTCAGCGTAGACAAGGATATCCTTGGCGGCGTCGTGCTGAAGGTCGGC
GACCGTGTTCTTGATGCCAGCCTGCGCGCACAGCTGGGCATTCTGAAGGATAACATCAAGAGGGGTGAGTAG

Upstream 100 bases:

>100_bases
ACATGATTGTTGATGCGACCGAAAAGCTGCTCAAAGAACGGCTGGACGGTAAAGAGCAGGAAAAGCTCATTGACAAGTAC
TTAACAAAGGTGGTGCTCAA

Downstream 100 bases:

>100_bases
GGCCATGCAGATTAAGACCGAAGAAATCAGCCAGATCATCGAATCGCAGATTCAGAATTACGAACAGCGAGTCGAGATGA
GCGAAACCGGTACCGTGCTT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTGNIAARRYARALFAIGQKQGLAELDAFGSELSAVAKAVEESPALARLFRNPLFSIEEKRAVLAKLLQAAGAGQTVSNF
CNLLADKGRLADLPDINAFYSLLLDAEKGIIRGELVTAIKLAKAKRDAVKEQLEKQAGQKIELNFSVDKDILGGVVLKVG
DRVLDASLRAQLGILKDNIKRGE

Sequences:

>Translated_183_residues
MTGNIAARRYARALFAIGQKQGLAELDAFGSELSAVAKAVEESPALARLFRNPLFSIEEKRAVLAKLLQAAGAGQTVSNF
CNLLADKGRLADLPDINAFYSLLLDAEKGIIRGELVTAIKLAKAKRDAVKEQLEKQAGQKIELNFSVDKDILGGVVLKVG
DRVLDASLRAQLGILKDNIKRGE
>Mature_182_residues
TGNIAARRYARALFAIGQKQGLAELDAFGSELSAVAKAVEESPALARLFRNPLFSIEEKRAVLAKLLQAAGAGQTVSNFC
NLLADKGRLADLPDINAFYSLLLDAEKGIIRGELVTAIKLAKAKRDAVKEQLEKQAGQKIELNFSVDKDILGGVVLKVGD
RVLDASLRAQLGILKDNIKRGE

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=170, Percent_Identity=28.8235294117647, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984710, Length=171, Percent_Identity=26.9005847953216, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71984717, Length=171, Percent_Identity=26.9005847953216, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24647054, Length=179, Percent_Identity=27.3743016759777, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_DESDG (Q313V7)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387484.1
- ProteinModelPortal:   Q313V7
- SMR:   Q313V7
- STRING:   Q313V7
- GeneID:   3755560
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_0988
- NMPDR:   fig|207559.3.peg.490
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   SIGDKYV
- ProtClustDB:   PRK13429
- BioCyc:   DDES207559:DDE_0988-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19701; Mature: 19570

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNIAARRYARALFAIGQKQGLAELDAFGSELSAVAKAVEESPALARLFRNPLFSIEEK
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHH
RAVLAKLLQAAGAGQTVSNFCNLLADKGRLADLPDINAFYSLLLDAEKGIIRGELVTAIK
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LAKAKRDAVKEQLEKQAGQKIELNFSVDKDILGGVVLKVGDRVLDASLRAQLGILKDNIK
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGE
CCC
>Mature Secondary Structure 
TGNIAARRYARALFAIGQKQGLAELDAFGSELSAVAKAVEESPALARLFRNPLFSIEEK
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHH
RAVLAKLLQAAGAGQTVSNFCNLLADKGRLADLPDINAFYSLLLDAEKGIIRGELVTAIK
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LAKAKRDAVKEQLEKQAGQKIELNFSVDKDILGGVVLKVGDRVLDASLRAQLGILKDNIK
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA