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The map label for this gene is cobL [H]

Identifier: 78355850

GI number: 78355850

Start: 822720

End: 823931

Strand: Reverse

Name: cobL [H]

Synonym: Dde_0803

Alternate gene names: 78355850

Gene position: 823931-822720 (Counterclockwise)

Preceding gene: 78355851

Following gene: 78355849

Centisome position: 22.09

GC content: 62.29

Gene sequence:

>1212_bases
ATGACCATTGATGTGGTTGGTCTCGGCATGGATGCCGACTCGCTGCCGGAATATCATACCGATGTTGTCGAAAGCGCTCA
GGTTCTGGTGGGCGGCAAGCGTCAGCTGGCCCTTTTTGACGATCATCCGGCAGAAAAGCTGCTCATCACGGCGCCGCTGG
GCGATATGCTGGAAAACATAGCCAGACTGGAAAGTCAGGGTAAATCCGTGGTGGTGCTGGCCGACGGCGACCCGCTGTTT
TTCGGCATAGGTGCGCGCCTTGTGGATGAATTCGGACCGGAAGGCGTGCGCATATGGCCCAATATCACATCGCTGCAGGC
TGCTGCCGCACGCGCCAAAGTGCCGTGGCAGGGCATCAGGGTGGTATCGCTGCACGGACGCGACGACATGCGTCCGCTCA
TGCAGGCCCTGCTGCAAAGCCCGTGGGTCTGCGTGCTCACAGACGGCCGCAGCATTCCTTCGGCCATTGCCCAGTGGCTG
CTGGACAGAGGCGCCGACTGGTTTTTTGTCTGGGTGTTTGAAAACATGGGACAGCCCAACGAGCATTTCGACCGCTACTC
TCTGCAGGATGCCGTCAAACGCAGTTTTTCGTCACTGAACACCGTTCTCATAGAACGCAGAGGCGGCCCCGAGCGTGTGC
TCGCCCCCGGCATACCCGACGACGAACTGCTGAGCGACGGCGGACTGGTGACCAAATGGCCCATACGCGCCGCGGGCATT
GCCGCGCTGCGTCCTTCGCACGGCATGACGGTGTGGGATCTGGGAGCAGGCAGCGGTGCCATGGGCATGGAAGCCTCATG
TCTGGTGGGTGAGGGCGTGGTGTGGTGCGTGGAACGCAAGGCGGCCCGCGTTGAGCACATCCGCGCCAACAGACGCCGCT
TCGGGGCGCTGCAGGTTGAAGTGGTGCACGGCACCATGCCTGCCTGTCTCGACGATCTGCCCGCCCCTGACAGAATTTTT
CTGGGCGGCGGACTCGGCTCCGGCGACGAAGTGCTGCATCAGGCATGCTCACGGCTCAATCCCGGCGGCCGCATTGTGGC
CCACTGCGTGCTGCTGGGGTCTTTGAACCGTGCTCGGGAAGCATTCACCGCAATGGGCTGGCCGTACGAAATCACACAGG
TGCAGTCTGCATGCGCCGTGCCGCTGGCCGGTGACCTGCGGCTGGACGCCAACAATCCCGTCTTTATCATAGCCGCCCAG
CGTCCGGAGTAA

Upstream 100 bases:

>100_bases
TTGACGGACGGCATCTGGCGCAGGCACATGACTAGCCCCCGCATGCGCCATGGTGTACCATAGTTCAAACAACCCGATGC
CATAACTGCAGGAGGCGACA

Downstream 100 bases:

>100_bases
GCCGTGCCGTACATCACCTCTGTCTTGTGCCGCGTTCTGACCATACTGTGGTTCGGTGCGGCCGTGGTGCTGGGTCCGGC
ACTGCAGGCCGCCGCTTCCG

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating)

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTIDVVGLGMDADSLPEYHTDVVESAQVLVGGKRQLALFDDHPAEKLLITAPLGDMLENIARLESQGKSVVVLADGDPLF
FGIGARLVDEFGPEGVRIWPNITSLQAAAARAKVPWQGIRVVSLHGRDDMRPLMQALLQSPWVCVLTDGRSIPSAIAQWL
LDRGADWFFVWVFENMGQPNEHFDRYSLQDAVKRSFSSLNTVLIERRGGPERVLAPGIPDDELLSDGGLVTKWPIRAAGI
AALRPSHGMTVWDLGAGSGAMGMEASCLVGEGVVWCVERKAARVEHIRANRRRFGALQVEVVHGTMPACLDDLPAPDRIF
LGGGLGSGDEVLHQACSRLNPGGRIVAHCVLLGSLNRAREAFTAMGWPYEITQVQSACAVPLAGDLRLDANNPVFIIAAQ
RPE

Sequences:

>Translated_403_residues
MTIDVVGLGMDADSLPEYHTDVVESAQVLVGGKRQLALFDDHPAEKLLITAPLGDMLENIARLESQGKSVVVLADGDPLF
FGIGARLVDEFGPEGVRIWPNITSLQAAAARAKVPWQGIRVVSLHGRDDMRPLMQALLQSPWVCVLTDGRSIPSAIAQWL
LDRGADWFFVWVFENMGQPNEHFDRYSLQDAVKRSFSSLNTVLIERRGGPERVLAPGIPDDELLSDGGLVTKWPIRAAGI
AALRPSHGMTVWDLGAGSGAMGMEASCLVGEGVVWCVERKAARVEHIRANRRRFGALQVEVVHGTMPACLDDLPAPDRIF
LGGGLGSGDEVLHQACSRLNPGGRIVAHCVLLGSLNRAREAFTAMGWPYEITQVQSACAVPLAGDLRLDANNPVFIIAAQ
RPE
>Mature_402_residues
TIDVVGLGMDADSLPEYHTDVVESAQVLVGGKRQLALFDDHPAEKLLITAPLGDMLENIARLESQGKSVVVLADGDPLFF
GIGARLVDEFGPEGVRIWPNITSLQAAAARAKVPWQGIRVVSLHGRDDMRPLMQALLQSPWVCVLTDGRSIPSAIAQWLL
DRGADWFFVWVFENMGQPNEHFDRYSLQDAVKRSFSSLNTVLIERRGGPERVLAPGIPDDELLSDGGLVTKWPIRAAGIA
ALRPSHGMTVWDLGAGSGAMGMEASCLVGEGVVWCVERKAARVEHIRANRRRFGALQVEVVHGTMPACLDDLPAPDRIFL
GGGLGSGDEVLHQACSRLNPGGRIVAHCVLLGSLNRAREAFTAMGWPYEITQVQSACAVPLAGDLRLDANNPVFIIAAQR
PE

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43612; Mature: 43480

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDVVGLGMDADSLPEYHTDVVESAQVLVGGKRQLALFDDHPAEKLLITAPLGDMLENI
CEEEEEEECCCHHCCCHHHHHHHHHHHHEECCCEEEEEECCCCCCEEEEECCHHHHHHHH
ARLESQGKSVVVLADGDPLFFGIGARLVDEFGPEGVRIWPNITSLQAAAARAKVPWQGIR
HHHHHCCCEEEEEECCCEEEEECHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCCCCEE
VVSLHGRDDMRPLMQALLQSPWVCVLTDGRSIPSAIAQWLLDRGADWFFVWVFENMGQPN
EEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCH
EHFDRYSLQDAVKRSFSSLNTVLIERRGGPERVLAPGIPDDELLSDGGLVTKWPIRAAGI
HHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEECCCCCCHHHHCCCCEEEECCCCCCCE
AALRPSHGMTVWDLGAGSGAMGMEASCLVGEGVVWCVERKAARVEHIRANRRRFGALQVE
EEECCCCCCEEEEECCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHCCEEEEE
VVHGTMPACLDDLPAPDRIFLGGGLGSGDEVLHQACSRLNPGGRIVAHCVLLGSLNRARE
EEECCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AFTAMGWPYEITQVQSACAVPLAGDLRLDANNPVFIIAAQRPE
HHHHCCCCEEHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCC
>Mature Secondary Structure 
TIDVVGLGMDADSLPEYHTDVVESAQVLVGGKRQLALFDDHPAEKLLITAPLGDMLENI
EEEEEEECCCHHCCCHHHHHHHHHHHHEECCCEEEEEECCCCCCEEEEECCHHHHHHHH
ARLESQGKSVVVLADGDPLFFGIGARLVDEFGPEGVRIWPNITSLQAAAARAKVPWQGIR
HHHHHCCCEEEEEECCCEEEEECHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCCCCEE
VVSLHGRDDMRPLMQALLQSPWVCVLTDGRSIPSAIAQWLLDRGADWFFVWVFENMGQPN
EEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCH
EHFDRYSLQDAVKRSFSSLNTVLIERRGGPERVLAPGIPDDELLSDGGLVTKWPIRAAGI
HHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEECCCCCCHHHHCCCCEEEECCCCCCCE
AALRPSHGMTVWDLGAGSGAMGMEASCLVGEGVVWCVERKAARVEHIRANRRRFGALQVE
EEECCCCCCEEEEECCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHCCEEEEE
VVHGTMPACLDDLPAPDRIFLGGGLGSGDEVLHQACSRLNPGGRIVAHCVLLGSLNRARE
EEECCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AFTAMGWPYEITQVQSACAVPLAGDLRLDANNPVFIIAAQRPE
HHHHCCCCEEHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]