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The map label for this gene is 78355695

Identifier: 78355695

GI number: 78355695

Start: 666685

End: 668073

Strand: Reverse

Name: 78355695

Synonym: Dde_0648

Alternate gene names: NA

Gene position: 668073-666685 (Counterclockwise)

Preceding gene: 78355696

Following gene: 78355694

Centisome position: 17.91

GC content: 58.03

Gene sequence:

>1389_bases
ATGCCTGAAGGTAAGTTCTGTAATAAACGTCCGGTCAACACCGAAGAGGACCTGAAGGCCCTGCTCGGCGACAAGGGCGG
CAATCAGTATTACGAAGAAATGAACTCGCTGGAAGTGGACACCGACGCGTTGTGGTCCACCATTGAAAAAACCTGCCAGT
CACGCATCCGCACCTGGCTGGAAATATGCGCCCACTGCGGCATGTGCGCCGACAGCTGCTTTCTGTACCGCGTAAACAAC
CGCGACCCCAAGCAGGTTCCCGCGTACAAGATACAGTCCACGCTGGGCGAAATGGTAAAACGCAAAGGCAAGGTGGACAA
CGCCTTCATGCAGCACTGCATGGAAGTGGCGTGGTCGCAGTGCACCTGCTGCAACCGTTGCGGCATGTACTGCCCCCACG
GCATAGACATGGGCGTCATGTTCAGCTACCTGCGCGGTCTCATGTACTCTCAGGGTTTTGTGCCGTGGGAACTGAAAATC
GGTTCCGGCATGCACCGCGTGTACAGCGCGCAGATGGACGTGACCACCGAGGACTGGGTAGAGACCTGCGAATGGATGGA
AGAGGAAACAGCCGAAGAATGGCCGGGTCTTACCATTCCCGTGGACAAAGTAGGCGCGGACATCATGTACACGCTGAACG
CCCGCGAACCCAAGCACTACCCTGAAGACCTTGCAGAAGCCGCCATCCTGTTCCATCTGGCCGGTGAAGACTGGACCGTG
CCCAGCGAAGGCTGGGAACAGACGTCGCTGGCCATGTTTGCCGGTGACTGGGCCGCGTGCAAAATGCAGGTGGACAAGGT
GTATGCCGCCATGGAACGCCTGAAACCCAAACGCATGGTCGGCACCGAATGCGGCCACGCACACCGCGCCACCGTCATCG
AAGGGCCGTACTGGGCAGGACGCGAAGACGGCCTGCCGCCGGTCAAGTGCATGCACTATGTGGAGTGGGTTGCCGAAGCT
CTGCGCGAAGGCAAGATCAAGATCGATCCTGCCAAAAAGATCAAGGAACCCTGTACGCTTCAGGATTCCTGCAACTATGT
GCGCAACCATGGTCTTGCCAACTTCACCCGCGAGATCATGAGCTATATTGCCGAAGACTACCGTGAAATGACCCCCAACC
GCGAGCATAACTACTGCTGCGGCGGCGGTGGCGGCTTTAACGGTATCGGCAAGTACCGCGCAGAGCGTAACAAGGCCCTG
CAGACCAAGCGCGACCAGATTCTGGCCACAGGCGCCACGCTGGTGGTGGCCCCCTGCCATAACTGCTGGGACGCCATCCG
CGACCTTGAAGAAGAATACGAAATCGGCATCAAGTGGAGCTTCCTCAAACCGCTCCTCATCAAGATGGCCATTGTGCCGG
ACCATCTGAAAGCCGCAGACGACGAATAA

Upstream 100 bases:

>100_bases
TCACGCGGCCAGCTGGGTATGGATTACAACATCAAGCGTGGCGGTATGAAGCGTACAGCCGGCTTCCCCTGGTAACCGGC
ACACCCAGAAGGAGTGAACA

Downstream 100 bases:

>100_bases
CAACAACAGGGGCGGAAGCAGACGCTTCCGCCCCGTTTCGCTCCCCGTGATGCCCCGTGCATCCGCATCCACGCAGGATA
CCCATGAAGCTTACCACACG

Product: hmc operon protein 6

Products: NA

Alternate protein names: HMC operon ORF 6 [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MPEGKFCNKRPVNTEEDLKALLGDKGGNQYYEEMNSLEVDTDALWSTIEKTCQSRIRTWLEICAHCGMCADSCFLYRVNN
RDPKQVPAYKIQSTLGEMVKRKGKVDNAFMQHCMEVAWSQCTCCNRCGMYCPHGIDMGVMFSYLRGLMYSQGFVPWELKI
GSGMHRVYSAQMDVTTEDWVETCEWMEEETAEEWPGLTIPVDKVGADIMYTLNAREPKHYPEDLAEAAILFHLAGEDWTV
PSEGWEQTSLAMFAGDWAACKMQVDKVYAAMERLKPKRMVGTECGHAHRATVIEGPYWAGREDGLPPVKCMHYVEWVAEA
LREGKIKIDPAKKIKEPCTLQDSCNYVRNHGLANFTREIMSYIAEDYREMTPNREHNYCCGGGGGFNGIGKYRAERNKAL
QTKRDQILATGATLVVAPCHNCWDAIRDLEEEYEIGIKWSFLKPLLIKMAIVPDHLKAADDE

Sequences:

>Translated_462_residues
MPEGKFCNKRPVNTEEDLKALLGDKGGNQYYEEMNSLEVDTDALWSTIEKTCQSRIRTWLEICAHCGMCADSCFLYRVNN
RDPKQVPAYKIQSTLGEMVKRKGKVDNAFMQHCMEVAWSQCTCCNRCGMYCPHGIDMGVMFSYLRGLMYSQGFVPWELKI
GSGMHRVYSAQMDVTTEDWVETCEWMEEETAEEWPGLTIPVDKVGADIMYTLNAREPKHYPEDLAEAAILFHLAGEDWTV
PSEGWEQTSLAMFAGDWAACKMQVDKVYAAMERLKPKRMVGTECGHAHRATVIEGPYWAGREDGLPPVKCMHYVEWVAEA
LREGKIKIDPAKKIKEPCTLQDSCNYVRNHGLANFTREIMSYIAEDYREMTPNREHNYCCGGGGGFNGIGKYRAERNKAL
QTKRDQILATGATLVVAPCHNCWDAIRDLEEEYEIGIKWSFLKPLLIKMAIVPDHLKAADDE
>Mature_461_residues
PEGKFCNKRPVNTEEDLKALLGDKGGNQYYEEMNSLEVDTDALWSTIEKTCQSRIRTWLEICAHCGMCADSCFLYRVNNR
DPKQVPAYKIQSTLGEMVKRKGKVDNAFMQHCMEVAWSQCTCCNRCGMYCPHGIDMGVMFSYLRGLMYSQGFVPWELKIG
SGMHRVYSAQMDVTTEDWVETCEWMEEETAEEWPGLTIPVDKVGADIMYTLNAREPKHYPEDLAEAAILFHLAGEDWTVP
SEGWEQTSLAMFAGDWAACKMQVDKVYAAMERLKPKRMVGTECGHAHRATVIEGPYWAGREDGLPPVKCMHYVEWVAEAL
REGKIKIDPAKKIKEPCTLQDSCNYVRNHGLANFTREIMSYIAEDYREMTPNREHNYCCGGGGGFNGIGKYRAERNKALQ
TKRDQILATGATLVVAPCHNCWDAIRDLEEEYEIGIKWSFLKPLLIKMAIVPDHLKAADDE

Specific function: HMWC (high-molecular-weight cytochrome c precursor), ORF2, ORF3, ORF4, ORF5, ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfa

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 52554; Mature: 52422

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEGKFCNKRPVNTEEDLKALLGDKGGNQYYEEMNSLEVDTDALWSTIEKTCQSRIRTWL
CCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EICAHCGMCADSCFLYRVNNRDPKQVPAYKIQSTLGEMVKRKGKVDNAFMQHCMEVAWSQ
HHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
CTCCNRCGMYCPHGIDMGVMFSYLRGLMYSQGFVPWELKIGSGMHRVYSAQMDVTTEDWV
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCHHHHH
ETCEWMEEETAEEWPGLTIPVDKVGADIMYTLNAREPKHYPEDLAEAAILFHLAGEDWTV
HHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHEECCCCCCC
PSEGWEQTSLAMFAGDWAACKMQVDKVYAAMERLKPKRMVGTECGHAHRATVIEGPYWAG
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCCC
REDGLPPVKCMHYVEWVAEALREGKIKIDPAKKIKEPCTLQDSCNYVRNHGLANFTREIM
CCCCCCHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHH
SYIAEDYREMTPNREHNYCCGGGGGFNGIGKYRAERNKALQTKRDQILATGATLVVAPCH
HHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEECCH
NCWDAIRDLEEEYEIGIKWSFLKPLLIKMAIVPDHLKAADDE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCC
>Mature Secondary Structure 
PEGKFCNKRPVNTEEDLKALLGDKGGNQYYEEMNSLEVDTDALWSTIEKTCQSRIRTWL
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EICAHCGMCADSCFLYRVNNRDPKQVPAYKIQSTLGEMVKRKGKVDNAFMQHCMEVAWSQ
HHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
CTCCNRCGMYCPHGIDMGVMFSYLRGLMYSQGFVPWELKIGSGMHRVYSAQMDVTTEDWV
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCHHHHH
ETCEWMEEETAEEWPGLTIPVDKVGADIMYTLNAREPKHYPEDLAEAAILFHLAGEDWTV
HHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHEECCCCCCC
PSEGWEQTSLAMFAGDWAACKMQVDKVYAAMERLKPKRMVGTECGHAHRATVIEGPYWAG
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCCC
REDGLPPVKCMHYVEWVAEALREGKIKIDPAKKIKEPCTLQDSCNYVRNHGLANFTREIM
CCCCCCHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHH
SYIAEDYREMTPNREHNYCCGGGGGFNGIGKYRAERNKALQTKRDQILATGATLVVAPCH
HHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEECCH
NCWDAIRDLEEEYEIGIKWSFLKPLLIKMAIVPDHLKAADDE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8335628 [H]