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The map label for this gene is stc [H]

Identifier: 78355336

GI number: 78355336

Start: 277236

End: 279137

Strand: Reverse

Name: stc [H]

Synonym: Dde_0289

Alternate gene names: 78355336

Gene position: 279137-277236 (Counterclockwise)

Preceding gene: 78355338

Following gene: 78355335

Centisome position: 7.48

GC content: 62.25

Gene sequence:

>1902_bases
ATGAGCATAGCCCTCATAGCCCCGTACGAAAGTCTGGCCACCCTGTGCCGGTCCATCTGTCAGGAACTGGATCTTGATGT
TTCGGTACATACCGGCAGCATGGAAGACGGAGTGCGCATTGCCAGAAACCTTATGGCCGAAGGTGTGGACTTTTTCATCA
GCCGCGGGCTGACAGCCCAGCTCATACGCGAGCAGTGCCCGCTGCCCGTGGCCGAGCTGGAGGTTTCGGCATTTGACATT
TACCTGTGCCTCGAACCGTTGCTCAGGAGCGGCAAAAGCATCGGCGTCGTCGGCCACAGTGACATTCTGCGCAAGGCCAA
GGGAGCCAGCGCGGCGCTGGGGTTCACCATCGACTTTTATGCCACGGCCCACCCCGGCGGCATGGGACACATAATGGAAG
CCGCCCGCAGACAGGGCATTGCCGCCATCGCAGGGGACGCTGTGGCGGCGCGCACGGCGGAACGGTACGGCATGGAAGGG
GTTCTGGTACAGAACGGTGCGGATTCCGTTACCAACACGCTGCAATATGCCGTTGCCACATACTCATACCTCACACGGCA
GGCCACCATGGCGGGCAGGCTGCAGACCGTGCTGGACCGCATGGACGGCGGGGCACTGCTGGCTTCGCCCGATGGCCGCA
TGCTGCACTGCAATGCGGCGGTACGCGCCATGCTGGAGCCTGATCAGGGCTGCACAGAAACGTCCATGGACGATCTTTTT
CCTCAGCTGGACTGGCGTGCCGTTCCCGAAGGACGCGCCGAAACCGTGCGCGAACTTGTCACCGTGGGCGGGTCCAAGCT
GGCGGTTACCGTCACCGGCACCATGCACGACGACGCCATGGATGCGCTCATATGCACCTTTCATGACGTACGTCAGATTG
AACAACTGGAACACAGCTTCCGCAAGAGCGCCAAACCGGACACCCCCACGGCGCGCCACACGTTCAGCTCCATTGTACAC
CGCAGTCCCGCCATGCACCGGTGCATCGCACGGGCCGAACAGTTTGCCGCAACGCAGAGCAGTATATTGCTTGTGGGCGA
AACGGGCACGGGCAAAGAACTTTTTGCCCAGAGTATCCACAACCACAGCCCGCGCGCGCAGGGCAATTTTGTGGCCATCA
ACTGCGGGGCACTGCCGGAAGACCTGCTGGAAAGCGAACTTTTCGGGTACGCGGGCGGCGCTTTCACGGGGGCACTGAAA
TCCGGCAAAGCCGGTATGTTTGAACTGGCGCACAACGGCACCCTGTTTCTGGACGAAGTAAACGCAACCAGCCCCAAACT
GCAGACGCGGCTGCTGCGCACCCTGCAGGAGCATGAAGTGATGCGCGTGGGTTCCACGGCGGTCATACCGGTGAACGTCC
GTGTCATCGCCGCATCAAACGCCCCGCTGGAGGCGGAGGTAAGCGCCGGAAGATTCCGCGCCGACCTGTTCTACCGCCTC
AATGTGCTCGACATCCGCATACCGCCGCTGCGTGAACGGCCGGAAGACATCCTGCTGCTGTTCAACATGTTTCTGGAACG
CTTCAGCGCGGAACAGCACCGCAGCACGCCGCCGGTGCCCCGCGGTACAGAGCGGAAAATCATGGCCCACGGCTGGCCGG
GAAACGTGCGCGAGCTGCAGAACTATGCGGAAAAGTATGCCATTCTGTATCCGGAGGAAGCCGCGCTGGGCGCCGACATA
ACTCCGTGGACGCCTCACGCCGCCCTCACGGCGGAACATGCACACACACCGGCGTACGGCACGGCCGCTGCTCCGGTTTC
CCGCGATCTGCTGCATGGAACACTGGAAGACATCACACGCGCAGCCGTTGCCGCCGTGCTGCATGAAGAAAACGGCAACC
TGAGCAGTGCGGCACGGCGGCTGGGCATCAGCCGCAACACCCTGCGCCGCAGGCTGGGATAA

Upstream 100 bases:

>100_bases
CATGCAGTTGAAAGAATGGCATGTTTTCAATTCTGGTCATCTGTTCAATTATGGTGCATCATTTTTGACCAGTTGATCAA
AAAATAACCGGAGCCACTTC

Downstream 100 bases:

>100_bases
AGGGGCGCCACCGGCGGCAAAGCTTGCCTGCAGGCAGACGCACAAAATTACAACATTCTGTATTTTTTGCTTAAACTATC
AGTGTGACCGTGTTTTGCAT

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MSIALIAPYESLATLCRSICQELDLDVSVHTGSMEDGVRIARNLMAEGVDFFISRGLTAQLIREQCPLPVAELEVSAFDI
YLCLEPLLRSGKSIGVVGHSDILRKAKGASAALGFTIDFYATAHPGGMGHIMEAARRQGIAAIAGDAVAARTAERYGMEG
VLVQNGADSVTNTLQYAVATYSYLTRQATMAGRLQTVLDRMDGGALLASPDGRMLHCNAAVRAMLEPDQGCTETSMDDLF
PQLDWRAVPEGRAETVRELVTVGGSKLAVTVTGTMHDDAMDALICTFHDVRQIEQLEHSFRKSAKPDTPTARHTFSSIVH
RSPAMHRCIARAEQFAATQSSILLVGETGTGKELFAQSIHNHSPRAQGNFVAINCGALPEDLLESELFGYAGGAFTGALK
SGKAGMFELAHNGTLFLDEVNATSPKLQTRLLRTLQEHEVMRVGSTAVIPVNVRVIAASNAPLEAEVSAGRFRADLFYRL
NVLDIRIPPLRERPEDILLLFNMFLERFSAEQHRSTPPVPRGTERKIMAHGWPGNVRELQNYAEKYAILYPEEAALGADI
TPWTPHAALTAEHAHTPAYGTAAAPVSRDLLHGTLEDITRAAVAAVLHEENGNLSSAARRLGISRNTLRRRLG

Sequences:

>Translated_633_residues
MSIALIAPYESLATLCRSICQELDLDVSVHTGSMEDGVRIARNLMAEGVDFFISRGLTAQLIREQCPLPVAELEVSAFDI
YLCLEPLLRSGKSIGVVGHSDILRKAKGASAALGFTIDFYATAHPGGMGHIMEAARRQGIAAIAGDAVAARTAERYGMEG
VLVQNGADSVTNTLQYAVATYSYLTRQATMAGRLQTVLDRMDGGALLASPDGRMLHCNAAVRAMLEPDQGCTETSMDDLF
PQLDWRAVPEGRAETVRELVTVGGSKLAVTVTGTMHDDAMDALICTFHDVRQIEQLEHSFRKSAKPDTPTARHTFSSIVH
RSPAMHRCIARAEQFAATQSSILLVGETGTGKELFAQSIHNHSPRAQGNFVAINCGALPEDLLESELFGYAGGAFTGALK
SGKAGMFELAHNGTLFLDEVNATSPKLQTRLLRTLQEHEVMRVGSTAVIPVNVRVIAASNAPLEAEVSAGRFRADLFYRL
NVLDIRIPPLRERPEDILLLFNMFLERFSAEQHRSTPPVPRGTERKIMAHGWPGNVRELQNYAEKYAILYPEEAALGADI
TPWTPHAALTAEHAHTPAYGTAAAPVSRDLLHGTLEDITRAAVAAVLHEENGNLSSAARRLGISRNTLRRRLG
>Mature_632_residues
SIALIAPYESLATLCRSICQELDLDVSVHTGSMEDGVRIARNLMAEGVDFFISRGLTAQLIREQCPLPVAELEVSAFDIY
LCLEPLLRSGKSIGVVGHSDILRKAKGASAALGFTIDFYATAHPGGMGHIMEAARRQGIAAIAGDAVAARTAERYGMEGV
LVQNGADSVTNTLQYAVATYSYLTRQATMAGRLQTVLDRMDGGALLASPDGRMLHCNAAVRAMLEPDQGCTETSMDDLFP
QLDWRAVPEGRAETVRELVTVGGSKLAVTVTGTMHDDAMDALICTFHDVRQIEQLEHSFRKSAKPDTPTARHTFSSIVHR
SPAMHRCIARAEQFAATQSSILLVGETGTGKELFAQSIHNHSPRAQGNFVAINCGALPEDLLESELFGYAGGAFTGALKS
GKAGMFELAHNGTLFLDEVNATSPKLQTRLLRTLQEHEVMRVGSTAVIPVNVRVIAASNAPLEAEVSAGRFRADLFYRLN
VLDIRIPPLRERPEDILLLFNMFLERFSAEQHRSTPPVPRGTERKIMAHGWPGNVRELQNYAEKYAILYPEEAALGADIT
PWTPHAALTAEHAHTPAYGTAAAPVSRDLLHGTLEDITRAAVAAVLHEENGNLSSAARRLGISRNTLRRRLG

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=318, Percent_Identity=42.1383647798742, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790437, Length=365, Percent_Identity=38.9041095890411, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI87082117, Length=321, Percent_Identity=42.6791277258567, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI1786524, Length=341, Percent_Identity=42.2287390029325, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1789087, Length=321, Percent_Identity=42.6791277258567, Blast_Score=226, Evalue=5e-60,
Organism=Escherichia coli, GI1788905, Length=321, Percent_Identity=42.6791277258567, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1789233, Length=364, Percent_Identity=36.5384615384615, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87082152, Length=344, Percent_Identity=40.9883720930233, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1790299, Length=350, Percent_Identity=36.2857142857143, Blast_Score=211, Evalue=2e-55,
Organism=Escherichia coli, GI1787583, Length=380, Percent_Identity=34.7368421052632, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87081872, Length=222, Percent_Identity=45.4954954954955, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI87081858, Length=474, Percent_Identity=27.8481012658228, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789828, Length=241, Percent_Identity=34.4398340248963, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68616; Mature: 68485

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIALIAPYESLATLCRSICQELDLDVSVHTGSMEDGVRIARNLMAEGVDFFISRGLTAQ
CCEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
LIREQCPLPVAELEVSAFDIYLCLEPLLRSGKSIGVVGHSDILRKAKGASAALGFTIDFY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCEEEEEEEEEE
ATAHPGGMGHIMEAARRQGIAAIAGDAVAARTAERYGMEGVLVQNGADSVTNTLQYAVAT
EECCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHH
YSYLTRQATMAGRLQTVLDRMDGGALLASPDGRMLHCNAAVRAMLEPDQGCTETSMDDLF
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHHHCCCCCCCCCCCHHHHC
PQLDWRAVPEGRAETVRELVTVGGSKLAVTVTGTMHDDAMDALICTFHDVRQIEQLEHSF
CCCCCEECCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RKSAKPDTPTARHTFSSIVHRSPAMHRCIARAEQFAATQSSILLVGETGTGKELFAQSIH
HHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
NHSPRAQGNFVAINCGALPEDLLESELFGYAGGAFTGALKSGKAGMFELAHNGTLFLDEV
CCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCEEEEEEC
NATSPKLQTRLLRTLQEHEVMRVGSTAVIPVNVRVIAASNAPLEAEVSAGRFRADLFYRL
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCEEECCCCHHEEEEEEEE
NVLDIRIPPLRERPEDILLLFNMFLERFSAEQHRSTPPVPRGTERKIMAHGWPGNVRELQ
EEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCEEECCCCCCHHHHH
NYAEKYAILYPEEAALGADITPWTPHAALTAEHAHTPAYGTAAAPVSRDLLHGTLEDITR
HHHHHEEEECCCHHHCCCCCCCCCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AAVAAVLHEENGNLSSAARRLGISRNTLRRRLG
HHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
SIALIAPYESLATLCRSICQELDLDVSVHTGSMEDGVRIARNLMAEGVDFFISRGLTAQ
CEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
LIREQCPLPVAELEVSAFDIYLCLEPLLRSGKSIGVVGHSDILRKAKGASAALGFTIDFY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCEEEEEEEEEE
ATAHPGGMGHIMEAARRQGIAAIAGDAVAARTAERYGMEGVLVQNGADSVTNTLQYAVAT
EECCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHH
YSYLTRQATMAGRLQTVLDRMDGGALLASPDGRMLHCNAAVRAMLEPDQGCTETSMDDLF
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHHHCCCCCCCCCCCHHHHC
PQLDWRAVPEGRAETVRELVTVGGSKLAVTVTGTMHDDAMDALICTFHDVRQIEQLEHSF
CCCCCEECCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RKSAKPDTPTARHTFSSIVHRSPAMHRCIARAEQFAATQSSILLVGETGTGKELFAQSIH
HHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
NHSPRAQGNFVAINCGALPEDLLESELFGYAGGAFTGALKSGKAGMFELAHNGTLFLDEV
CCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCEEEEEEC
NATSPKLQTRLLRTLQEHEVMRVGSTAVIPVNVRVIAASNAPLEAEVSAGRFRADLFYRL
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCEEECCCCHHEEEEEEEE
NVLDIRIPPLRERPEDILLLFNMFLERFSAEQHRSTPPVPRGTERKIMAHGWPGNVRELQ
EEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCEEECCCCCCHHHHH
NYAEKYAILYPEEAALGADITPWTPHAALTAEHAHTPAYGTAAAPVSRDLLHGTLEDITR
HHHHHEEEECCCHHHCCCCCCCCCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AAVAAVLHEENGNLSSAARRLGISRNTLRRRLG
HHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA