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The map label for this gene is yabD [H]

Identifier: 78355121

GI number: 78355121

Start: 63304

End: 64134

Strand: Reverse

Name: yabD [H]

Synonym: Dde_0074

Alternate gene names: 78355121

Gene position: 64134-63304 (Counterclockwise)

Preceding gene: 78355122

Following gene: 78355120

Centisome position: 1.72

GC content: 61.49

Gene sequence:

>831_bases
ATGTCAAAAAGCAAACATAAAACTCCGCCCCCTGCCGCGCATACGCTCGGACTGCCGCCGGCCGGTGTGGACTCCCATGC
CCATCTGGATCTGGACGCCCTGCGGCCCGACCTTGACGAAATACTGACCCGTGCGCGTGAAGCAGGCGTCTCCCACATCG
GACAGGTTTTTCTGGGCCCCCAGGCATGGGCGCAAAACCGCCATCTTTTCGACGCTTATCCGCAGGTTTTTTTCATTCTG
GGGCTGCACCCCGGCGATGCCGACGCCTGCGACGAAAATGCCGTCACTGCCATGAAGCAGGCCTTTGCCACTGACCCGCG
GCTGAAAGCCGTGGGCGAAATAGGGCTGGACTACTACTGGGACGACCACCCGAGGGAACTGCAGCAGAAAACCTTTGTCA
TGCAGTTGCGCATGGCCGTTCAGATAGACAAACCCGTGGTCATTCATTCGCGCGATGCCGACGAAGACACCGTGCGGCTG
CTTGAAGCGGAAGGGTTTGCGGGACGTCCTTTGCTGTGGCACTGCTTCGGCGCGGACGCGGCACTGGCTGAACGCATTGT
GCGCAACGGCTGGCATGTCTCCGTTCCCGGCCCCGTCACCTATCCGGCCAACAACGCCCTGCGTGAAGCGCTTTCTGTCA
TACCGGCAGACAGACTGATGCTGGAGACAGACTGCCCGTACCTGACACCCGTACCGTGGCGCGGCAGACGCAACGAACCC
GCGCTGGCAGCATTCACCGGGGCCTGTGTGGCCCGATGTCTGGGAATCGACCCCGCAGAACTCTGGACCCGGTGCGGAAA
CAACGCCCGCGCCTTTTTCGGGATACAATGA

Upstream 100 bases:

>100_bases
CACTATTCACTGGAAAAACAACGTGAGGCTGTGCTCGACCTGTGGTCGCAGGCCGCCCTCGGAAACATATTCTCTTAGTC
TGTCCGCCGGATATCCGCCC

Downstream 100 bases:

>100_bases
AACATATGACAGATCTCACCGAAACGCGGCCCATGTGCAAAGGCATCGCCATGCGCGAGCTTTTTGAAGCTGTGGAAATG
TTCAACGCCGGCGACTGGTA

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSKSKHKTPPPAAHTLGLPPAGVDSHAHLDLDALRPDLDEILTRAREAGVSHIGQVFLGPQAWAQNRHLFDAYPQVFFIL
GLHPGDADACDENAVTAMKQAFATDPRLKAVGEIGLDYYWDDHPRELQQKTFVMQLRMAVQIDKPVVIHSRDADEDTVRL
LEAEGFAGRPLLWHCFGADAALAERIVRNGWHVSVPGPVTYPANNALREALSVIPADRLMLETDCPYLTPVPWRGRRNEP
ALAAFTGACVARCLGIDPAELWTRCGNNARAFFGIQ

Sequences:

>Translated_276_residues
MSKSKHKTPPPAAHTLGLPPAGVDSHAHLDLDALRPDLDEILTRAREAGVSHIGQVFLGPQAWAQNRHLFDAYPQVFFIL
GLHPGDADACDENAVTAMKQAFATDPRLKAVGEIGLDYYWDDHPRELQQKTFVMQLRMAVQIDKPVVIHSRDADEDTVRL
LEAEGFAGRPLLWHCFGADAALAERIVRNGWHVSVPGPVTYPANNALREALSVIPADRLMLETDCPYLTPVPWRGRRNEP
ALAAFTGACVARCLGIDPAELWTRCGNNARAFFGIQ
>Mature_275_residues
SKSKHKTPPPAAHTLGLPPAGVDSHAHLDLDALRPDLDEILTRAREAGVSHIGQVFLGPQAWAQNRHLFDAYPQVFFILG
LHPGDADACDENAVTAMKQAFATDPRLKAVGEIGLDYYWDDHPRELQQKTFVMQLRMAVQIDKPVVIHSRDADEDTVRLL
EAEGFAGRPLLWHCFGADAALAERIVRNGWHVSVPGPVTYPANNALREALSVIPADRLMLETDCPYLTPVPWRGRRNEPA
LAAFTGACVARCLGIDPAELWTRCGNNARAFFGIQ

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=219, Percent_Identity=31.5068493150685, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI110349734, Length=263, Percent_Identity=28.1368821292776, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI110349730, Length=263, Percent_Identity=27.3764258555133, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI226061853, Length=268, Percent_Identity=26.865671641791, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI226061614, Length=252, Percent_Identity=26.5873015873016, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI226061595, Length=225, Percent_Identity=27.1111111111111, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=32.8125, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=31.7647058823529, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI48994985, Length=263, Percent_Identity=32.319391634981, Blast_Score=104, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=29.8932384341637, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71980746, Length=260, Percent_Identity=23.8461538461538, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=25.4416961130742, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30422; Mature: 30291

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSKHKTPPPAAHTLGLPPAGVDSHAHLDLDALRPDLDEILTRAREAGVSHIGQVFLGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
QAWAQNRHLFDAYPQVFFILGLHPGDADACDENAVTAMKQAFATDPRLKAVGEIGLDYYW
HHHHCCCCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEE
DDHPRELQQKTFVMQLRMAVQIDKPVVIHSRDADEDTVRLLEAEGFAGRPLLWHCFGADA
CCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCH
ALAERIVRNGWHVSVPGPVTYPANNALREALSVIPADRLMLETDCPYLTPVPWRGRRNEP
HHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCC
ALAAFTGACVARCLGIDPAELWTRCGNNARAFFGIQ
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
SKSKHKTPPPAAHTLGLPPAGVDSHAHLDLDALRPDLDEILTRAREAGVSHIGQVFLGP
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
QAWAQNRHLFDAYPQVFFILGLHPGDADACDENAVTAMKQAFATDPRLKAVGEIGLDYYW
HHHHCCCCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEE
DDHPRELQQKTFVMQLRMAVQIDKPVVIHSRDADEDTVRLLEAEGFAGRPLLWHCFGADA
CCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCH
ALAERIVRNGWHVSVPGPVTYPANNALREALSVIPADRLMLETDCPYLTPVPWRGRRNEP
HHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCC
ALAAFTGACVARCLGIDPAELWTRCGNNARAFFGIQ
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]