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The map label for this gene is ribD [H]

Identifier: 304570589

GI number: 304570589

Start: 2455027

End: 2456148

Strand: Direct

Name: ribD [H]

Synonym: NA

Alternate gene names: 304570589

Gene position: 2455027-2456148 (Clockwise)

Preceding gene: 78357476

Following gene: 78357478

Centisome position: 65.81

GC content: 62.21

Gene sequence:

>1122_bases
GTGTCACACGATCATCCTTTTTCTTCCTTCATGCTTGAGGCGGTGGCGCTGGCCGAAAAAGGCCGCTGGGCCACATCGCC
CAATCCCTGCGTGGGTGCCGTGCTGGTAAAAGACGGGCAGACCGTGGCGCGCGGCTGGCACACGGCCTATGGTAAACCGC
ATGCCGAAATAGAATGCCTGCGCGATGCCGCCCGACGCGGAGTGAACCCCGCCGAATGCACTCTGGTGGTAACGCTGGAA
CCATGCAACCACACCGGAAAAACGCCCCCGTGCTCCATAGCCGTGCTGCAGGCCGGTATCCGGCACGTGGTGGTGGGTAT
GATGGACCCCAACCCCGTGGCACAGGGCGGAGCAAATTTTCTGCGCGAAAACGGAGTCACCGTTGAAACAGGGGTCTGCC
GTCAGGAATGCGAAGATGTGGTGGACGACTTCATCACATGGAAAAAAACACCCCTGCCCTACACCATCATCAAGCTTGCC
TCCACTCTGGACGGCCGCATAGCCACCCGTACAGGGCACTCACGCTGGATAAGCGGCGAAGAATCGCGCCGCCGTGTGCA
TGAACTGCGCAGACACGCCGATGCCGTCATCGTCGGGGGAGGAACCTTCCGCGCTGACAATCCGCAACTTACCTGCCGGC
TGGAAGGAATCCGCCGGCAACCGCTGGCCGTGGTGGTCACCTCGCAGCTGCCCGATGCCGGAGCCCCCATGCACCTGCTG
CAGCAACGCCCGCATGAAACAATTTTCTGGACACCCCGCGCAGTGGCGGCTTCCGAAAAGGCCGATGCCCTGCGCGCTCT
GGGTGTGCGCGTGACCGGACTGGACCGCAACTGCAAGGGCAGACTGGATCTGCATACCGCCCTTGCGGGCCTGCGCAGCG
AATACGACTGCTACCACACCCTGTGCGAAGGCGGCGGCATGCTGGCTCTTTCCATGCTGGAAATGAATGTGGCGCAGGAA
CTGGAACTGCATATGGCCCCCAAACTGCTGGCCGACGCACAGGCCAGACCGCTGTTTGACGGCCGCACACCGTCCACCAT
GGAACAGGCGCTGGGCCTGCGCATCTGTAATGTCGCCCGCAGCGGCGAAGACGTTATCCTGACCTTGCGCCCGAGGAAAT
AA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:
NA

Sequences:

>Translated_373_residues
MSHDHPFSSFMLEAVALAEKGRWATSPNPCVGAVLVKDGQTVARGWHTAYGKPHAEIECLRDAARRGVNPAECTLVVTLE
PCNHTGKTPPCSIAVLQAGIRHVVVGMMDPNPVAQGGANFLRENGVTVETGVCRQECEDVVDDFITWKKTPLPYTIIKLA
STLDGRIATRTGHSRWISGEESRRRVHELRRHADAVIVGGGTFRADNPQLTCRLEGIRRQPLAVVVTSQLPDAGAPMHLL
QQRPHETIFWTPRAVAASEKADALRALGVRVTGLDRNCKGRLDLHTALAGLRSEYDCYHTLCEGGGMLALSMLEMNVAQE
LELHMAPKLLADAQARPLFDGRTPSTMEQALGLRICNVARSGEDVILTLRPRK
>Mature_372_residues
SHDHPFSSFMLEAVALAEKGRWATSPNPCVGAVLVKDGQTVARGWHTAYGKPHAEIECLRDAARRGVNPAECTLVVTLEP
CNHTGKTPPCSIAVLQAGIRHVVVGMMDPNPVAQGGANFLRENGVTVETGVCRQECEDVVDDFITWKKTPLPYTIIKLAS
TLDGRIATRTGHSRWISGEESRRRVHELRRHADAVIVGGGTFRADNPQLTCRLEGIRRQPLAVVVTSQLPDAGAPMHLLQ
QRPHETIFWTPRAVAASEKADALRALGVRVTGLDRNCKGRLDLHTALAGLRSEYDCYHTLCEGGGMLALSMLEMNVAQEL
ELHMAPKLLADAQARPLFDGRTPSTMEQALGLRICNVARSGEDVILTLRPRK

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=374, Percent_Identity=35.8288770053476, Blast_Score=197, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40743; Mature: 40612

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDHPFSSFMLEAVALAEKGRWATSPNPCVGAVLVKDGQTVARGWHTAYGKPHAEIECL
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHCHHHHCCCCCHHHHHH
RDAARRGVNPAECTLVVTLEPCNHTGKTPPCSIAVLQAGIRHVVVGMMDPNPVAQGGANF
HHHHHCCCCHHHEEEEEEEECCCCCCCCCCHHHHHHHHCHHHEEEECCCCCCHHHCCHHH
LRENGVTVETGVCRQECEDVVDDFITWKKTPLPYTIIKLASTLDGRIATRTGHSRWISGE
HHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCH
ESRRRVHELRRHADAVIVGGGTFRADNPQLTCRLEGIRRQPLAVVVTSQLPDAGAPMHLL
HHHHHHHHHHHCCCEEEECCCEEECCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHHHH
QQRPHETIFWTPRAVAASEKADALRALGVRVTGLDRNCKGRLDLHTALAGLRSEYDCYHT
HCCCCCEEEECCCHHHCCHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LCEGGGMLALSMLEMNVAQELELHMAPKLLADAQARPLFDGRTPSTMEQALGLRICNVAR
HHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SGEDVILTLRPRK
CCCCEEEEECCCC
>Mature Secondary Structure 
SHDHPFSSFMLEAVALAEKGRWATSPNPCVGAVLVKDGQTVARGWHTAYGKPHAEIECL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHCHHHHCCCCCHHHHHH
RDAARRGVNPAECTLVVTLEPCNHTGKTPPCSIAVLQAGIRHVVVGMMDPNPVAQGGANF
HHHHHCCCCHHHEEEEEEEECCCCCCCCCCHHHHHHHHCHHHEEEECCCCCCHHHCCHHH
LRENGVTVETGVCRQECEDVVDDFITWKKTPLPYTIIKLASTLDGRIATRTGHSRWISGE
HHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCH
ESRRRVHELRRHADAVIVGGGTFRADNPQLTCRLEGIRRQPLAVVVTSQLPDAGAPMHLL
HHHHHHHHHHHCCCEEEECCCEEECCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHHHH
QQRPHETIFWTPRAVAASEKADALRALGVRVTGLDRNCKGRLDLHTALAGLRSEYDCYHT
HCCCCCEEEECCCHHHCCHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LCEGGGMLALSMLEMNVAQELELHMAPKLLADAQARPLFDGRTPSTMEQALGLRICNVAR
HHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SGEDVILTLRPRK
CCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]