Click here to switch to the map view.

The map label for this gene is gcvR [C]

Identifier: 78224737

GI number: 78224737

Start: 3988471

End: 3989040

Strand: Reverse

Name: gcvR [C]

Synonym: Gmet_3554

Alternate gene names: 78224737

Gene position: 3989040-3988471 (Counterclockwise)

Preceding gene: 78224738

Following gene: 78224736

Centisome position: 99.79

GC content: 60.0

Gene sequence:

>570_bases
ATGATGAGCACGAAGAAAACGGATTCCCTTGCCCACTACGCCGTCACGGTTGTGGGAAAAGACCGCCCCGGTATCGTGGC
CGCAACGGCCGGGGTCCTCTACCGGCTGGGGTGCAACGTCGAGGATTCCAGCTCCACCATGCTCGGGGGGGAGTTCTCCA
TGATTCTCATCGTCTCCCATGAGAAACCCTTCAGCAAGGGGAGGATTCTGGAGGAGTTCCGGGGAGTGGCGGAAGAGATG
GGGCTCACGGTGGCGGCCCGGACCCTTTCCCCCGACGAGGTGGCCTACCAGGCGCCGGAAGGGGAGCTCTGCATGGTTTC
GGTCTACGGCTCCGACCGGCCCGGGATCATCTACCGCGTGACAAATGAGCTGGCAGAGCGGAAGGTGAATATTACCGACC
TCAATACCAAGCTCATCGGCACCAAGGAAGAGCCGGTCTACGTCCTGATGCTGGAGGCGGCACTACCGGAAGGTATTGTC
GTGGAAGACGTGGCGGCAATGTTCGACAAGATTAAGAAGGAGATGAACGTGGAGATTTCGGTGCGATCCATCACGCCGGT
CTCCCTCTGA

Upstream 100 bases:

>100_bases
AGGAACCTCATCCGCACCTTGCCATTGGCGGCGCCATCTGCTAGAGTCGACGTCTACCCGCTGCGGAATAGCGCGCCGAT
CACCGAAGGAGACCCTTTCC

Downstream 100 bases:

>100_bases
CGCCATGCCCGCACAGCCCATCCTCTGCTATCCCCATCCCGTTCTAAAGAAGGTGAGCCATGCCGTCGCCGTTATCGACG
ACGAGATCCGGGGTCTTATC

Product: amino acid-binding ACT

Products: NA

Alternate protein names: Glycine Cleavage System Transcriptional Repressor; ACT Domain-Containing Protein; ACT Domain Protein

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MMSTKKTDSLAHYAVTVVGKDRPGIVAATAGVLYRLGCNVEDSSSTMLGGEFSMILIVSHEKPFSKGRILEEFRGVAEEM
GLTVAARTLSPDEVAYQAPEGELCMVSVYGSDRPGIIYRVTNELAERKVNITDLNTKLIGTKEEPVYVLMLEAALPEGIV
VEDVAAMFDKIKKEMNVEISVRSITPVSL

Sequences:

>Translated_189_residues
MMSTKKTDSLAHYAVTVVGKDRPGIVAATAGVLYRLGCNVEDSSSTMLGGEFSMILIVSHEKPFSKGRILEEFRGVAEEM
GLTVAARTLSPDEVAYQAPEGELCMVSVYGSDRPGIIYRVTNELAERKVNITDLNTKLIGTKEEPVYVLMLEAALPEGIV
VEDVAAMFDKIKKEMNVEISVRSITPVSL
>Mature_189_residues
MMSTKKTDSLAHYAVTVVGKDRPGIVAATAGVLYRLGCNVEDSSSTMLGGEFSMILIVSHEKPFSKGRILEEFRGVAEEM
GLTVAARTLSPDEVAYQAPEGELCMVSVYGSDRPGIIYRVTNELAERKVNITDLNTKLIGTKEEPVYVLMLEAALPEGIV
VEDVAAMFDKIKKEMNVEISVRSITPVSL

Specific function: Negative Transcriptional Regulator Of The Glycine Cleavage System Operon (Gcv). Does Not Autoregulate Its Own Expression. It Is Not Yet Known How Gcvr Acts As A Repressor. It Does Not Seem To Bind DNA. It Could Interact With Gcva And Suppress Its Activat

COG id: COG2716

COG function: function code E; Glycine cleavage system regulatory protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20559; Mature: 20559

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSTKKTDSLAHYAVTVVGKDRPGIVAATAGVLYRLGCNVEDSSSTMLGGEFSMILIVSH
CCCCCCCCCEEEEEEEEEECCCCCEEEEHHHEEEEECCCCCCCCCEEECCCEEEEEEEEC
EKPFSKGRILEEFRGVAEEMGLTVAARTLSPDEVAYQAPEGELCMVSVYGSDRPGIIYRV
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHEEECCCCCEEEEEEECCCCCCEEEEE
TNELAERKVNITDLNTKLIGTKEEPVYVLMLEAALPEGIVVEDVAAMFDKIKKEMNVEIS
CHHHHHCCCCEEECCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEE
VRSITPVSL
EEEECCCCC
>Mature Secondary Structure
MMSTKKTDSLAHYAVTVVGKDRPGIVAATAGVLYRLGCNVEDSSSTMLGGEFSMILIVSH
CCCCCCCCCEEEEEEEEEECCCCCEEEEHHHEEEEECCCCCCCCCEEECCCEEEEEEEEC
EKPFSKGRILEEFRGVAEEMGLTVAARTLSPDEVAYQAPEGELCMVSVYGSDRPGIIYRV
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHEEECCCCCEEEEEEECCCCCCEEEEE
TNELAERKVNITDLNTKLIGTKEEPVYVLMLEAALPEGIVVEDVAAMFDKIKKEMNVEIS
CHHHHHCCCCEEECCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEE
VRSITPVSL
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA