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The map label for this gene is tadA [H]

Identifier: 78224707

GI number: 78224707

Start: 3957024

End: 3957539

Strand: Reverse

Name: tadA [H]

Synonym: Gmet_3524

Alternate gene names: 78224707

Gene position: 3957539-3957024 (Counterclockwise)

Preceding gene: 78224708

Following gene: 78224706

Centisome position: 99.0

GC content: 62.6

Gene sequence:

>516_bases
ATGGTTCGCCGTAAAGCCGAGGGAGTGCGGGACGACAGCTACTGGATGGGGAAGGCCCTGCGAGAAGCGGAAAAGGCCGC
TGCCCGGGACGAGGTCCCCATTGGTGCTGTCGTTGTCAGAAATGGCGCAGTAATCGGTCGTGGGCACAACCTGCGGGAAA
ATAAGCAGGACCCCTCGGCCCACGCCGAAATGATAGCCATCCGTCAGGCCGCCAGGCGACTCGGGTGCTGGCGCCTTACG
GGATGCGTTCTCTATGTGACCCTTGAGCCGTGCCTCATGTGCATGGGGGCCATCATCCTCGCCCGGTTCGACCGGGTGGT
CTTCGGCTGCCATGATCCCAAGGGAGGCGCGGCCGGTTCCCTCTACGACCTCTCCGATGACCGCCGGCTCAATCACCGGG
TTGAACTCACTTCCCGGGTGCGGGAAGAGGAATGTTCCGCAATCCTGAGCGGTTTTTTCGCCGATCTCCGCACACGGAAA
AAGAAGGCCCGTCGCGCACCATCGGCCGGTATCTGA

Upstream 100 bases:

>100_bases
AGAAGGGAGACCCGATGATGACCCCTCGCGAGGTGCTCATGCTGGATCCGAAGCCCCTGTACGTTCAGTATCAATAACCG
ACGGAGAGGAACCGGATCGG

Downstream 100 bases:

>100_bases
TCTCTCCTCCTGTAAGCCTTTTCCTCCAGTAATTGACACAAGCGTGTAAAAATCATCCTTGCGGAGAGGGGGGAGAGGGA
TTACACTTTACTCCACTTTG

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MVRRKAEGVRDDSYWMGKALREAEKAAARDEVPIGAVVVRNGAVIGRGHNLRENKQDPSAHAEMIAIRQAARRLGCWRLT
GCVLYVTLEPCLMCMGAIILARFDRVVFGCHDPKGGAAGSLYDLSDDRRLNHRVELTSRVREEECSAILSGFFADLRTRK
KKARRAPSAGI

Sequences:

>Translated_171_residues
MVRRKAEGVRDDSYWMGKALREAEKAAARDEVPIGAVVVRNGAVIGRGHNLRENKQDPSAHAEMIAIRQAARRLGCWRLT
GCVLYVTLEPCLMCMGAIILARFDRVVFGCHDPKGGAAGSLYDLSDDRRLNHRVELTSRVREEECSAILSGFFADLRTRK
KKARRAPSAGI
>Mature_171_residues
MVRRKAEGVRDDSYWMGKALREAEKAAARDEVPIGAVVVRNGAVIGRGHNLRENKQDPSAHAEMIAIRQAARRLGCWRLT
GCVLYVTLEPCLMCMGAIILARFDRVVFGCHDPKGGAAGSLYDLSDDRRLNHRVELTSRVREEECSAILSGFFADLRTRK
KKARRAPSAGI

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=161, Percent_Identity=31.6770186335404, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI145693172, Length=156, Percent_Identity=48.7179487179487, Blast_Score=146, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17541138, Length=162, Percent_Identity=32.7160493827161, Blast_Score=93, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=43.75, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17555996, Length=81, Percent_Identity=48.1481481481481, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6325319, Length=149, Percent_Identity=32.2147651006711, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355527, Length=160, Percent_Identity=31.875, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18978; Mature: 18978

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRKAEGVRDDSYWMGKALREAEKAAARDEVPIGAVVVRNGAVIGRGHNLRENKQDPSA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEECCCCCCCCCCCCHH
HAEMIAIRQAARRLGCWRLTGCVLYVTLEPCLMCMGAIILARFDRVVFGCHDPKGGAAGS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LYDLSDDRRLNHRVELTSRVREEECSAILSGFFADLRTRKKKARRAPSAGI
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVRRKAEGVRDDSYWMGKALREAEKAAARDEVPIGAVVVRNGAVIGRGHNLRENKQDPSA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEECCCCCCCCCCCCHH
HAEMIAIRQAARRLGCWRLTGCVLYVTLEPCLMCMGAIILARFDRVVFGCHDPKGGAAGS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LYDLSDDRRLNHRVELTSRVREEECSAILSGFFADLRTRKKKARRAPSAGI
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]