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The map label for this gene is menB [H]

Identifier: 78224496

GI number: 78224496

Start: 3719175

End: 3720299

Strand: Reverse

Name: menB [H]

Synonym: Gmet_3305

Alternate gene names: 78224496

Gene position: 3720299-3719175 (Counterclockwise)

Preceding gene: 78224497

Following gene: 78224495

Centisome position: 93.07

GC content: 62.58

Gene sequence:

>1125_bases
ATGGCTAGGACAAATGTGATGATCGCCGAGACCTTTCCGGAATATCTGGTCGACCACAACCTGATCGACTGTGAGGTGGA
GAGCCTCTGCAACGGCATGGTCCGGTACGAGAAACGGCCGGCCAGGCGCCGTGACGGGTCGGTGGCGGAAGGGCTCTACA
ACGCCTGGATCATCTTCAACAACCCCAGGCAGTACAACTCCTACACGACCGAGATGGTCAAGGCCACCATCCTTGCCTTC
CGTCGCGCCTCCGTCGATCGCGAGGTGAATGCCGTGGTCTTCACCGGCGTTGGCGACAAGGCGTTCTGCACCGGCGGCAA
CACCAAGGAGTACGCGGAGTACTATGCCGGCAACCCCCAGGAGTACCGGCAGTACATGCGGCTGTTCAACGACATGGTCT
CCTCCATCCTCGGCTGCGACCGGCCGGTGATCTGCCGGGTGAACGGCATGCGGATCGGCGGCGGCCAGGAGATCGGCATG
GCCTGCGACTTCTCCATCGCCCAGGATCTGGCGAAATTCGGGCAGGCTGGCCCCAAGCACGGCTCAGCCGCCATCGGCGG
GGCAACCGACTTCCTGCCGATCATGATTGGCTGCGAGCAGGCCATGGTGTCCGGGACCCTCTGCGAGCCCTTCTCGGCCC
ACAAGGCGGCGCGGCTCGGCATCATCGCCGATGTGGTCCCGGCCCTCAAGGTTGGCGGTACGTTCGTCGCCAACCCCACC
GTCGTCACCGACCGGTTCCTGGACGAGTATGGCAGGGTAGTCCAGGGCGAATTCAAGACCGGCGCCGACTTCAAGGCGGG
ACAGGCCCGGATCAAGGAAGGGGAGGTCGATCTCAGCCTCCTCGATGAGAAAGTGGAAGAGCTCTGCGCCAAGCTTCTGG
AGACCTTCCCCGAGTGCATGACCAAGAGCTTGGAAGAGTTGCGCAAACCAAAGCTCCAGGCGTGGAACCTGAACAAGGAG
AACTCCCGCGCGTGGCTGGCGCTCAACATGATGAACGAGGCCCGCATCGGCTTCCGGGCGTTCAATGAAGGAACCAAGGA
GACGGGGCGCGAGATCGATTTCGTCAAGCTTCGCCGTCAGCTGGCCGAGGGAACGCCCTGGGCCGAGGAGTTGATTGAGA
TTTGA

Upstream 100 bases:

>100_bases
ACCCGCATGGTGACGGGGAGGGCCCTGTTGTTCCCGTAAAGGGTAACAACAGGAATGTATCGTGACATCAGGCAGATAGC
CTTAAGAGCGGAGAAAGAGA

Downstream 100 bases:

>100_bases
TGCTTCCGGTCGTCACGATGATCCGAGATGTCATCAGGTGCGTAACGTGCCGGCAGGTGTGCCGAACCAATGAAACCATC
CAACGGGGGTATCGTTTATG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MARTNVMIAETFPEYLVDHNLIDCEVESLCNGMVRYEKRPARRRDGSVAEGLYNAWIIFNNPRQYNSYTTEMVKATILAF
RRASVDREVNAVVFTGVGDKAFCTGGNTKEYAEYYAGNPQEYRQYMRLFNDMVSSILGCDRPVICRVNGMRIGGGQEIGM
ACDFSIAQDLAKFGQAGPKHGSAAIGGATDFLPIMIGCEQAMVSGTLCEPFSAHKAARLGIIADVVPALKVGGTFVANPT
VVTDRFLDEYGRVVQGEFKTGADFKAGQARIKEGEVDLSLLDEKVEELCAKLLETFPECMTKSLEELRKPKLQAWNLNKE
NSRAWLALNMMNEARIGFRAFNEGTKETGREIDFVKLRRQLAEGTPWAEELIEI

Sequences:

>Translated_374_residues
MARTNVMIAETFPEYLVDHNLIDCEVESLCNGMVRYEKRPARRRDGSVAEGLYNAWIIFNNPRQYNSYTTEMVKATILAF
RRASVDREVNAVVFTGVGDKAFCTGGNTKEYAEYYAGNPQEYRQYMRLFNDMVSSILGCDRPVICRVNGMRIGGGQEIGM
ACDFSIAQDLAKFGQAGPKHGSAAIGGATDFLPIMIGCEQAMVSGTLCEPFSAHKAARLGIIADVVPALKVGGTFVANPT
VVTDRFLDEYGRVVQGEFKTGADFKAGQARIKEGEVDLSLLDEKVEELCAKLLETFPECMTKSLEELRKPKLQAWNLNKE
NSRAWLALNMMNEARIGFRAFNEGTKETGREIDFVKLRRQLAEGTPWAEELIEI
>Mature_373_residues
ARTNVMIAETFPEYLVDHNLIDCEVESLCNGMVRYEKRPARRRDGSVAEGLYNAWIIFNNPRQYNSYTTEMVKATILAFR
RASVDREVNAVVFTGVGDKAFCTGGNTKEYAEYYAGNPQEYRQYMRLFNDMVSSILGCDRPVICRVNGMRIGGGQEIGMA
CDFSIAQDLAKFGQAGPKHGSAAIGGATDFLPIMIGCEQAMVSGTLCEPFSAHKAARLGIIADVVPALKVGGTFVANPTV
VTDRFLDEYGRVVQGEFKTGADFKAGQARIKEGEVDLSLLDEKVEELCAKLLETFPECMTKSLEELRKPKLQAWNLNKEN
SRAWLALNMMNEARIGFRAFNEGTKETGREIDFVKLRRQLAEGTPWAEELIEI

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) (Probable) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=171, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1788597, Length=194, Percent_Identity=33.5051546391753, Blast_Score=107, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17554946, Length=223, Percent_Identity=26.9058295964126, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17549921, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=215, Percent_Identity=23.2558139534884, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=189, Percent_Identity=32.8042328042328, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653477, Length=189, Percent_Identity=32.8042328042328, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654903, Length=170, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 41613; Mature: 41482

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTNVMIAETFPEYLVDHNLIDCEVESLCNGMVRYEKRPARRRDGSVAEGLYNAWIIFN
CCCCCEEEHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEC
NPRQYNSYTTEMVKATILAFRRASVDREVNAVVFTGVGDKAFCTGGNTKEYAEYYAGNPQ
CCHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHCCCHH
EYRQYMRLFNDMVSSILGCDRPVICRVNGMRIGGGQEIGMACDFSIAQDLAKFGQAGPKH
HHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCEECHHHHHHHHHHCCCCCCC
GSAAIGGATDFLPIMIGCEQAMVSGTLCEPFSAHKAARLGIIADVVPALKVGGTFVANPT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
VVTDRFLDEYGRVVQGEFKTGADFKAGQARIKEGEVDLSLLDEKVEELCAKLLETFPECM
HHHHHHHHHHCHHEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TKSLEELRKPKLQAWNLNKENSRAWLALNMMNEARIGFRAFNEGTKETGREIDFVKLRRQ
HHHHHHHHCCCCEEECCCCCCCCEEEEEEEHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
LAEGTPWAEELIEI
HHCCCCHHHHHHCC
>Mature Secondary Structure 
ARTNVMIAETFPEYLVDHNLIDCEVESLCNGMVRYEKRPARRRDGSVAEGLYNAWIIFN
CCCCEEEHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEC
NPRQYNSYTTEMVKATILAFRRASVDREVNAVVFTGVGDKAFCTGGNTKEYAEYYAGNPQ
CCHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHCCCHH
EYRQYMRLFNDMVSSILGCDRPVICRVNGMRIGGGQEIGMACDFSIAQDLAKFGQAGPKH
HHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCEECHHHHHHHHHHCCCCCCC
GSAAIGGATDFLPIMIGCEQAMVSGTLCEPFSAHKAARLGIIADVVPALKVGGTFVANPT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
VVTDRFLDEYGRVVQGEFKTGADFKAGQARIKEGEVDLSLLDEKVEELCAKLLETFPECM
HHHHHHHHHHCHHEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TKSLEELRKPKLQAWNLNKENSRAWLALNMMNEARIGFRAFNEGTKETGREIDFVKLRRQ
HHHHHHHHCCCCEEECCCCCCCCEEEEEEEHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
LAEGTPWAEELIEI
HHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA