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The map label for this gene is cat2 [H]

Identifier: 78224495

GI number: 78224495

Start: 3717764

End: 3719077

Strand: Reverse

Name: cat2 [H]

Synonym: Gmet_3304

Alternate gene names: 78224495

Gene position: 3719077-3717764 (Counterclockwise)

Preceding gene: 78224496

Following gene: 78224494

Centisome position: 93.04

GC content: 59.59

Gene sequence:

>1314_bases
ATGGAAAGCGTAAAAAATGCCAAGCGCAGCTATGAAAAGGAGTACCGGCAGAAAGTCTGCTCGCCGGTAGAAGCCGCGGC
AGTCGTCAAGTCGGGGGATTGTCTCTGCTTCCCCATCAGCGTCGGGGAGCCGACGCTCTTCGTGAGGGCGTTGGCGGCCC
GCAGGCACGAGTTGGAAGGGGTCGTCATCAACCAGCAGCATCACCTCTGCCCCGATTACTTCACGGAGGATTCGGCTCCG
CACATAAAGGTCAACGCATGGTTCACGAGCCACGTTTCCCGCGAGGCGGTCCAGAAGGGGTGGGCGGATTTCGTTCCCAA
CTATTTCCATGAGGTTCCCCGGCTCCTGCGTGATTACTGGCCCGTTGACGTGGCCGGGACCGTGGTTTCCCCCATGGACG
AGCATGGCTACTTCACCTGCAGCCTCTCCGTGGCCTACACCATGGAGGCGATTAAGAAGGCAAAGAAAGTGGTGGTGCAG
GTGAACCCCCAGGCCCCCCGGACCCACGGCAACTGCCATATTCACATCTCCGAGGTGGACCACATCATCGAGTGTGACGA
GCCCCTGGCATCCTTGACCATCCCCCCCATCACGCCAGTTGAAGAGGCTATCGGCGGCTATATCTCGGAACTTGTGGAAG
ACGGTTCATGCCTGCAACTCGGCTGGGGCGGCATACCGAACTCGGTCTGCAAGGCACTGCTGCACAAGAAGGATCTGGGG
ATACACACCGAGCTCCTTTCCGACGGCATGGTGGACCTGATGCTTTCAGGGGCGGTCAACAACTCCCGCAAGCAAACCCA
TACCGGCAAGACCGTCGCCACGTTCGCCCTCGGCACCAGCCGGCTCTATGAGTTCATGAACGAAAATCCGCGGATAGAGA
TGCACCCGGTGGATTACGTCAACTATCCCCACAACATCGGCAAAAACGACAACGTGGTGTCGATCAACGCCACGCTTGAG
GTGGACCTGCTCGGCCAGTGCTGTTCCGAGTCGTTCGGGCATCTGCAGTACAGCGGAACCGGCGGCCAGGCCGATTTCGT
CCGGGGTTCGAATATCTCCAACGGCGGGAAAGGCTTCATCACCACGGCGTCCACCGCAAAAAACGGAACCATATCACGCA
TCGTTCCGACCTTGGCGCCGGGGGCATCTGTCACCACCGGGAAGAACGATGTGGATTATGTGGTCACCGAGTTCGGGGTG
GCCAAGCTCCGGGGGCAGACTGCCCGGCAACGGGCCATCAACCTGATCAACATCGCACACCCCGATTTCCGGGGCGAACT
CACCGAGGCAGCCAGAAGGATGAACCGCATTTAG

Upstream 100 bases:

>100_bases
TGATGCTTCCGGTCGTCACGATGATCCGAGATGTCATCAGGTGCGTAACGTGCCGGCAGGTGTGCCGAACCAATGAAACC
ATCCAACGGGGGTATCGTTT

Downstream 100 bases:

>100_bases
AGCCTGTCGGCAGTACTGTCCCGCAACCGGTTTGGGAGGGGTACGTGATGAGATTTACATTGATGTATTGTGCAGCGGCT
TTGGTAATGCTTGCGGTGCC

Product: Acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MESVKNAKRSYEKEYRQKVCSPVEAAAVVKSGDCLCFPISVGEPTLFVRALAARRHELEGVVINQQHHLCPDYFTEDSAP
HIKVNAWFTSHVSREAVQKGWADFVPNYFHEVPRLLRDYWPVDVAGTVVSPMDEHGYFTCSLSVAYTMEAIKKAKKVVVQ
VNPQAPRTHGNCHIHISEVDHIIECDEPLASLTIPPITPVEEAIGGYISELVEDGSCLQLGWGGIPNSVCKALLHKKDLG
IHTELLSDGMVDLMLSGAVNNSRKQTHTGKTVATFALGTSRLYEFMNENPRIEMHPVDYVNYPHNIGKNDNVVSINATLE
VDLLGQCCSESFGHLQYSGTGGQADFVRGSNISNGGKGFITTASTAKNGTISRIVPTLAPGASVTTGKNDVDYVVTEFGV
AKLRGQTARQRAINLINIAHPDFRGELTEAARRMNRI

Sequences:

>Translated_437_residues
MESVKNAKRSYEKEYRQKVCSPVEAAAVVKSGDCLCFPISVGEPTLFVRALAARRHELEGVVINQQHHLCPDYFTEDSAP
HIKVNAWFTSHVSREAVQKGWADFVPNYFHEVPRLLRDYWPVDVAGTVVSPMDEHGYFTCSLSVAYTMEAIKKAKKVVVQ
VNPQAPRTHGNCHIHISEVDHIIECDEPLASLTIPPITPVEEAIGGYISELVEDGSCLQLGWGGIPNSVCKALLHKKDLG
IHTELLSDGMVDLMLSGAVNNSRKQTHTGKTVATFALGTSRLYEFMNENPRIEMHPVDYVNYPHNIGKNDNVVSINATLE
VDLLGQCCSESFGHLQYSGTGGQADFVRGSNISNGGKGFITTASTAKNGTISRIVPTLAPGASVTTGKNDVDYVVTEFGV
AKLRGQTARQRAINLINIAHPDFRGELTEAARRMNRI
>Mature_437_residues
MESVKNAKRSYEKEYRQKVCSPVEAAAVVKSGDCLCFPISVGEPTLFVRALAARRHELEGVVINQQHHLCPDYFTEDSAP
HIKVNAWFTSHVSREAVQKGWADFVPNYFHEVPRLLRDYWPVDVAGTVVSPMDEHGYFTCSLSVAYTMEAIKKAKKVVVQ
VNPQAPRTHGNCHIHISEVDHIIECDEPLASLTIPPITPVEEAIGGYISELVEDGSCLQLGWGGIPNSVCKALLHKKDLG
IHTELLSDGMVDLMLSGAVNNSRKQTHTGKTVATFALGTSRLYEFMNENPRIEMHPVDYVNYPHNIGKNDNVVSINATLE
VDLLGQCCSESFGHLQYSGTGGQADFVRGSNISNGGKGFITTASTAKNGTISRIVPTLAPGASVTTGKNDVDYVVTEFGV
AKLRGQTARQRAINLINIAHPDFRGELTEAARRMNRI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=461, Percent_Identity=23.2104121475054, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563853, Length=426, Percent_Identity=39.2018779342723, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17538151, Length=426, Percent_Identity=36.8544600938967, Blast_Score=252, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6319456, Length=393, Percent_Identity=25.9541984732824, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21358615, Length=420, Percent_Identity=40.7142857142857, Blast_Score=290, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 47912; Mature: 47912

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESVKNAKRSYEKEYRQKVCSPVEAAAVVKSGDCLCFPISVGEPTLFVRALAARRHELEG
CCHHHHHHHHHHHHHHHHHCCHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHHHHHCCE
VVINQQHHLCPDYFTEDSAPHIKVNAWFTSHVSREAVQKGWADFVPNYFHEVPRLLRDYW
EEECCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCHHHHCHHHHHHHHHHHHHCC
PVDVAGTVVSPMDEHGYFTCSLSVAYTMEAIKKAKKVVVQVNPQAPRTHGNCHIHISEVD
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEECCC
HIIECDEPLASLTIPPITPVEEAIGGYISELVEDGSCLQLGWGGIPNSVCKALLHKKDLG
HHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCC
IHTELLSDGMVDLMLSGAVNNSRKQTHTGKTVATFALGTSRLYEFMNENPRIEMHPVDYV
HHHHHHHCCHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCEEECCCCCC
NYPHNIGKNDNVVSINATLEVDLLGQCCSESFGHLQYSGTGGQADFVRGSNISNGGKGFI
CCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHCCEEECCCCCCCEEEECCCCCCCCCEEE
TTASTAKNGTISRIVPTLAPGASVTTGKNDVDYVVTEFGVAKLRGQTARQRAINLINIAH
EECCCCCCCCHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHEEEECC
PDFRGELTEAARRMNRI
CCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MESVKNAKRSYEKEYRQKVCSPVEAAAVVKSGDCLCFPISVGEPTLFVRALAARRHELEG
CCHHHHHHHHHHHHHHHHHCCHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHHHHHCCE
VVINQQHHLCPDYFTEDSAPHIKVNAWFTSHVSREAVQKGWADFVPNYFHEVPRLLRDYW
EEECCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCHHHHCHHHHHHHHHHHHHCC
PVDVAGTVVSPMDEHGYFTCSLSVAYTMEAIKKAKKVVVQVNPQAPRTHGNCHIHISEVD
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEECCC
HIIECDEPLASLTIPPITPVEEAIGGYISELVEDGSCLQLGWGGIPNSVCKALLHKKDLG
HHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCC
IHTELLSDGMVDLMLSGAVNNSRKQTHTGKTVATFALGTSRLYEFMNENPRIEMHPVDYV
HHHHHHHCCHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCEEECCCCCC
NYPHNIGKNDNVVSINATLEVDLLGQCCSESFGHLQYSGTGGQADFVRGSNISNGGKGFI
CCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHCCEEECCCCCCCEEEECCCCCCCCCEEE
TTASTAKNGTISRIVPTLAPGASVTTGKNDVDYVVTEFGVAKLRGQTARQRAINLINIAH
EECCCCCCCCHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHEEEECC
PDFRGELTEAARRMNRI
CCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]