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The map label for this gene is allR [H]

Identifier: 78224477

GI number: 78224477

Start: 3697191

End: 3697946

Strand: Direct

Name: allR [H]

Synonym: Gmet_3286

Alternate gene names: 78224477

Gene position: 3697191-3697946 (Clockwise)

Preceding gene: 78224476

Following gene: 78224478

Centisome position: 92.49

GC content: 58.47

Gene sequence:

>756_bases
ATGAAACAGGATCTCTCACTTCACCAGACAGGATCAGTGGAACACGTCATCGCACTGCTGGAAACACTGACCGAAGACAC
TCCGATCCACTCTGTGGCCACCATCTCGTCGCGGCTCGGCATTAGCCGCAATAAGGCGTTTCGCCTCCTCGCTACCCTTG
AGTCCCGAGAACTCGTGGAAAAGGACAAGCATGGCTCATACCGCCTCGGCACCGCGGCTGCGGACCTGGCTCGACGTCTT
TTGGACAACGTGAACATAATCGGCCACGCACGGCCGGTGCTGAATGAACTGGCGAGAAGACACGGAGAGGCGGTCTACCT
GTCGGTCCTGAAGGACGACGACGTGATATTTCTCGATGTTGCCGATTGTGCCGGGGTAGAAGGTTCCGGCTCCCTTGTCG
GCAAGCGGTTCCCCTCCCTGGCCACCAGCGCCGGCAAGGCAATCCGGTCGCTCCAATCACGGGATCTGCTGGAAAAACTC
CTGGGAGGGAAGCGCGGGCGTCAGCGCTCCGTGGATCTGGAGGCGATCATCGGTGAACTTGAAGTCATCAGAAAACACGG
TGTTGCCATTGACGAGGGGGGGGGAACCAGCAGCGCGGCAACGGCGGTACGAGACTATACCGGAAAAATTGTTTGCGCCC
TGACGGTGCTCGGCCCGTCGGTCAGAATGCTTAGGGACCGCATCGAGAAGGAAATTGCACCGTCCCTCATGGAGGGTGCT
GAGGTGCTTTCTCTTAGATTCGGCTATGCGAAGTAA

Upstream 100 bases:

>100_bases
GACAAGCCAAACTAAAAACGATGTTTGGTATTTGAATTGCTTTGTTTTAACGTCAACGGAATGAGCTTCATTCTCCCCAC
AATGATGCCGAGGCGAATAC

Downstream 100 bases:

>100_bases
CGGGAAAGGAGAACGAAACGTTTGTGCGGAACGGATGGGGAATTGAGTCGGCAATACCAATACACTTGGAAAAGGAGCGG
TGACCATGGCAGCAGATCAG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKQDLSLHQTGSVEHVIALLETLTEDTPIHSVATISSRLGISRNKAFRLLATLESRELVEKDKHGSYRLGTAAADLARRL
LDNVNIIGHARPVLNELARRHGEAVYLSVLKDDDVIFLDVADCAGVEGSGSLVGKRFPSLATSAGKAIRSLQSRDLLEKL
LGGKRGRQRSVDLEAIIGELEVIRKHGVAIDEGGGTSSAATAVRDYTGKIVCALTVLGPSVRMLRDRIEKEIAPSLMEGA
EVLSLRFGYAK

Sequences:

>Translated_251_residues
MKQDLSLHQTGSVEHVIALLETLTEDTPIHSVATISSRLGISRNKAFRLLATLESRELVEKDKHGSYRLGTAAADLARRL
LDNVNIIGHARPVLNELARRHGEAVYLSVLKDDDVIFLDVADCAGVEGSGSLVGKRFPSLATSAGKAIRSLQSRDLLEKL
LGGKRGRQRSVDLEAIIGELEVIRKHGVAIDEGGGTSSAATAVRDYTGKIVCALTVLGPSVRMLRDRIEKEIAPSLMEGA
EVLSLRFGYAK
>Mature_251_residues
MKQDLSLHQTGSVEHVIALLETLTEDTPIHSVATISSRLGISRNKAFRLLATLESRELVEKDKHGSYRLGTAAADLARRL
LDNVNIIGHARPVLNELARRHGEAVYLSVLKDDDVIFLDVADCAGVEGSGSLVGKRFPSLATSAGKAIRSLQSRDLLEKL
LGGKRGRQRSVDLEAIIGELEVIRKHGVAIDEGGGTSSAATAVRDYTGKIVCALTVLGPSVRMLRDRIEKEIAPSLMEGA
EVLSLRFGYAK

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=246, Percent_Identity=26.8292682926829, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786715, Length=227, Percent_Identity=26.431718061674, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1786468, Length=213, Percent_Identity=24.4131455399061, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=24.2063492063492, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789999, Length=244, Percent_Identity=26.2295081967213, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27086; Mature: 27086

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDLSLHQTGSVEHVIALLETLTEDTPIHSVATISSRLGISRNKAFRLLATLESRELVE
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KDKHGSYRLGTAAADLARRLLDNVNIIGHARPVLNELARRHGEAVYLSVLKDDDVIFLDV
HCCCCCEECHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCEEEEEEECCCCEEEEEE
ADCAGVEGSGSLVGKRFPSLATSAGKAIRSLQSRDLLEKLLGGKRGRQRSVDLEAIIGEL
HHHCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
EVIRKHGVAIDEGGGTSSAATAVRDYTGKIVCALTVLGPSVRMLRDRIEKEIAPSLMEGA
HHHHHCCCEEECCCCCHHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHH
EVLSLRFGYAK
HHHHHHCCCCC
>Mature Secondary Structure
MKQDLSLHQTGSVEHVIALLETLTEDTPIHSVATISSRLGISRNKAFRLLATLESRELVE
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KDKHGSYRLGTAAADLARRLLDNVNIIGHARPVLNELARRHGEAVYLSVLKDDDVIFLDV
HCCCCCEECHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCEEEEEEECCCCEEEEEE
ADCAGVEGSGSLVGKRFPSLATSAGKAIRSLQSRDLLEKLLGGKRGRQRSVDLEAIIGEL
HHHCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
EVIRKHGVAIDEGGGTSSAATAVRDYTGKIVCALTVLGPSVRMLRDRIEKEIAPSLMEGA
HHHHHCCCEEECCCCCHHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHH
EVLSLRFGYAK
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA