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The map label for this gene is cheW [H]

Identifier: 78224456

GI number: 78224456

Start: 3674187

End: 3674681

Strand: Direct

Name: cheW [H]

Synonym: Gmet_3265

Alternate gene names: 78224456

Gene position: 3674187-3674681 (Clockwise)

Preceding gene: 78224455

Following gene: 78224457

Centisome position: 91.91

GC content: 58.79

Gene sequence:

>495_bases
ATGGAAACTGCGCTGCAGACCAAAGTAGAGGAATCGAGAAGCGAACTGATCCAACTCGTGAGCTTCAAGCTGGAGCAGGA
GGAGTATGGGGTAAACGTCCTGAAGGTGCGCGAGATCATCCGGATGCCGAGCATCACCCGCGTTCCCAATACCCCCCACT
ATATCGAGGGGGTGATCAACCTGCGGGGCAAGGTAATCCCCATCATCTCCATGCGCAAGCGTTTCAGCCTCCCCGAGGGG
GAGACAAGCAGCCAGACGAGGATCATGGTCATCGACATGGAAGGGGAGCTGATGGGATTCGTGGTTGATGCGGTCTCAGA
GGTGATCCGGATCTCCGAGAGCGAGATCCAGCCTCCGCCGGCCGTGGTCAACAGCGCCGTGGAGCAGGAGTGCCTCGCGG
GGGTCATCAACCAGACCGACCGTCTCCTCTTCTTCCTCAACCTGGAGAAACTCATCTCCCGGGACGAGCGAAGCCTGTTC
AGCGGCATGATGTGA

Upstream 100 bases:

>100_bases
GCATGAGAACACTCTTTGCATCGAGCAGTGAAGTGTTTCCTTGCAAGCGACCAGGGCGATGAATTCCGATCAGTCGGAAC
GGATAAGGAGGAAGAGGGCG

Downstream 100 bases:

>100_bases
CACAATAAATATCTTTCACATTCGTGAGGAATAGCAGATGGCGATTGAGTGCGAAGACCAGGAACTCCTGGATGGATTTT
TGACCGAAACGGCGGAACTG

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
METALQTKVEESRSELIQLVSFKLEQEEYGVNVLKVREIIRMPSITRVPNTPHYIEGVINLRGKVIPIISMRKRFSLPEG
ETSSQTRIMVIDMEGELMGFVVDAVSEVIRISESEIQPPPAVVNSAVEQECLAGVINQTDRLLFFLNLEKLISRDERSLF
SGMM

Sequences:

>Translated_164_residues
METALQTKVEESRSELIQLVSFKLEQEEYGVNVLKVREIIRMPSITRVPNTPHYIEGVINLRGKVIPIISMRKRFSLPEG
ETSSQTRIMVIDMEGELMGFVVDAVSEVIRISESEIQPPPAVVNSAVEQECLAGVINQTDRLLFFLNLEKLISRDERSLF
SGMM
>Mature_164_residues
METALQTKVEESRSELIQLVSFKLEQEEYGVNVLKVREIIRMPSITRVPNTPHYIEGVINLRGKVIPIISMRKRFSLPEG
ETSSQTRIMVIDMEGELMGFVVDAVSEVIRISESEIQPPPAVVNSAVEQECLAGVINQTDRLLFFLNLEKLISRDERSLF
SGMM

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=144, Percent_Identity=36.1111111111111, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18581; Mature: 18581

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METALQTKVEESRSELIQLVSFKLEQEEYGVNVLKVREIIRMPSITRVPNTPHYIEGVIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LRGKVIPIISMRKRFSLPEGETSSQTRIMVIDMEGELMGFVVDAVSEVIRISESEIQPPP
CCCCEEHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCH
AVVNSAVEQECLAGVINQTDRLLFFLNLEKLISRDERSLFSGMM
HHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHCHHHHHHHHCCC
>Mature Secondary Structure
METALQTKVEESRSELIQLVSFKLEQEEYGVNVLKVREIIRMPSITRVPNTPHYIEGVIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LRGKVIPIISMRKRFSLPEGETSSQTRIMVIDMEGELMGFVVDAVSEVIRISESEIQPPP
CCCCEEHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCH
AVVNSAVEQECLAGVINQTDRLLFFLNLEKLISRDERSLFSGMM
HHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]