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The map label for this gene is cheA [H]

Identifier: 78224457

GI number: 78224457

Start: 3674719

End: 3676542

Strand: Direct

Name: cheA [H]

Synonym: Gmet_3266

Alternate gene names: 78224457

Gene position: 3674719-3676542 (Clockwise)

Preceding gene: 78224456

Following gene: 78224458

Centisome position: 91.93

GC content: 62.55

Gene sequence:

>1824_bases
ATGGCGATTGAGTGCGAAGACCAGGAACTCCTGGATGGATTTTTGACCGAAACGGCGGAACTGCTCGAGAAGCTTGACGA
CGATCTGGTTGCCCTGGAAAAGACCCCATCGGACGCGGAGCTCATGAACGGCATTTTCCGGTCGATCCATACGGTGAAAG
GGGCCTCCAGCTTTCTCGGTTTTGAGCTTCTCGTGAAGGTCACCCACAAGACCGAGGACGTCCTGAACCGCATGCGGCGG
GGAGAGCTGGAGGTAACCCCGGAGGTCATGGACGTGATCCTGGAGGCGGTGGACCTGGTGAAACTCCTGGTGAGCGACAT
CAAGGGGGGAGACATCGTCGAGCGTGAAATCGACGGGACCGTCGGCAAACTCCTCCCCTTCCTCTCGGAAAACGCCAAGG
AAGCGACGGTTCTCAAGCCGTCGGCGACCACCGTGACGCCTTCAGCGCCGGCCGAAGCGGCTCCGACGCCCCAAGCGACG
GAAACGGAAACCCACCCCTCTGCCGAACTTTCTCCGGCCCCGGAGGCAGCGCCGGTCAAGGCACCCGAGCCCGCTCCCCG
CGTCCAGGCGCCCCCGCCCCCTGCCCCCCGTGACGACAAAAAGGGGGATGACCTGGCGGACAACACCACGGTCCGGGTGG
ATGTGAAACGGCTCGACGACCTCATGAACCAGGTGGGGGAGCTGGTTCTTGAGCGCAACCGGATGATGCAGCTCAACACC
GATTTCAACGACGGCGGAGACGACACCTTCGGCGAAGAGTTCGGCAAGCTCTCCAAGCGGATCAGCTTCGTTACCTCGGA
ACTCCAGATGCAGGTCCTCAAGATGCGGATGATCCCGGTGGAAAAGGTCTTCAAGAAGTTCCCCCGCATCGTGCGCAACC
TGGCCCGGGACCTGGGCAAGGAAGTGGATCTCCTCGTCTTCGGCGAAGAGACCGAACTGGATCGCTCAGTGGTGGATGAA
ATCGGCGACCCGCTGATCCACCTGATCCGTAACGCCATGGACCACGGCCTGGAGACCCCCGACGAACGGATGGCGGCCGG
CAAGCCCCGCAAGGGGACCCTGATCCTCTCGGCGGCCCATGAGGGGAACCAGATCGTCATCAGCATCAAGGACGACGGCA
AAGGGATTGATCCCGAGAGAATCGCGAGAAAAGCGAAGGAAAAAGGGCTGGTAACCGACGAGCAACTGGCCGCCATGGGA
CAGCGTGAGATCCTGGACCTGATCTTTCTCCCCGGCTTCTCCACCAAGGAGAAGGCCACGGACCTCTCGGGACGCGGCGT
CGGCATGGACGTGGTCAGAACCAACATCAAAAAGCTGAACGGCATCATCGATATCCGCAGCGAACTGGGGCAGGGGTCCG
AGTTCATCCTGAAGCTCCCCCTTACCCTCGCCATCATCCAGTCGCTCCTGGTGGAGGTGGAGGACGAGACCTACTCGATC
CCCCTGGCGGCGGTCCTGGAGACGCTCCGGGTGGAGGAACGGGAATTCCACACCATCGGCGGCCAGGAGGTGCTCAAGCT
TCGAGATTCGGTGCTCCCCCTCATGCGGCTGCAGAAGATTTTCAACGTCGCCCCGAGCGAGCGGAGCCGTGTCGCCTGCT
ACGTGGTTGTCGTGGGGGTTGCCGAGAAGCGGGTCGGGCTTGTGGTTTCGCGGCTTCTGGGGCAGCAGGAGGTGGCCATC
AAGTCCCTCGGCAAGTACCTGGCAAACCTCCCCGGCATTGCCGGCTCCACCATCCTCGGTGACGGACGGGTCACCCTCAT
CATCGACCCCGCGGGGCTCATGGAGAACAGCGACGGAAGCGGCGGCGGCCGCATTGCCGCCTGA

Upstream 100 bases:

>100_bases
TTCCTCAACCTGGAGAAACTCATCTCCCGGGACGAGCGAAGCCTGTTCAGCGGCATGATGTGACACAATAAATATCTTTC
ACATTCGTGAGGAATAGCAG

Downstream 100 bases:

>100_bases
CCCGCCGGCCGAAAGCACGATACTCAACCGAAGAAGGGACGCCAGTGACACTCTCTGACAAGGATTTCGAGGTCCTCAGG
GACTTCATCTACAATCACTG

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MAIECEDQELLDGFLTETAELLEKLDDDLVALEKTPSDAELMNGIFRSIHTVKGASSFLGFELLVKVTHKTEDVLNRMRR
GELEVTPEVMDVILEAVDLVKLLVSDIKGGDIVEREIDGTVGKLLPFLSENAKEATVLKPSATTVTPSAPAEAAPTPQAT
ETETHPSAELSPAPEAAPVKAPEPAPRVQAPPPPAPRDDKKGDDLADNTTVRVDVKRLDDLMNQVGELVLERNRMMQLNT
DFNDGGDDTFGEEFGKLSKRISFVTSELQMQVLKMRMIPVEKVFKKFPRIVRNLARDLGKEVDLLVFGEETELDRSVVDE
IGDPLIHLIRNAMDHGLETPDERMAAGKPRKGTLILSAAHEGNQIVISIKDDGKGIDPERIARKAKEKGLVTDEQLAAMG
QREILDLIFLPGFSTKEKATDLSGRGVGMDVVRTNIKKLNGIIDIRSELGQGSEFILKLPLTLAIIQSLLVEVEDETYSI
PLAAVLETLRVEEREFHTIGGQEVLKLRDSVLPLMRLQKIFNVAPSERSRVACYVVVVGVAEKRVGLVVSRLLGQQEVAI
KSLGKYLANLPGIAGSTILGDGRVTLIIDPAGLMENSDGSGGGRIAA

Sequences:

>Translated_607_residues
MAIECEDQELLDGFLTETAELLEKLDDDLVALEKTPSDAELMNGIFRSIHTVKGASSFLGFELLVKVTHKTEDVLNRMRR
GELEVTPEVMDVILEAVDLVKLLVSDIKGGDIVEREIDGTVGKLLPFLSENAKEATVLKPSATTVTPSAPAEAAPTPQAT
ETETHPSAELSPAPEAAPVKAPEPAPRVQAPPPPAPRDDKKGDDLADNTTVRVDVKRLDDLMNQVGELVLERNRMMQLNT
DFNDGGDDTFGEEFGKLSKRISFVTSELQMQVLKMRMIPVEKVFKKFPRIVRNLARDLGKEVDLLVFGEETELDRSVVDE
IGDPLIHLIRNAMDHGLETPDERMAAGKPRKGTLILSAAHEGNQIVISIKDDGKGIDPERIARKAKEKGLVTDEQLAAMG
QREILDLIFLPGFSTKEKATDLSGRGVGMDVVRTNIKKLNGIIDIRSELGQGSEFILKLPLTLAIIQSLLVEVEDETYSI
PLAAVLETLRVEEREFHTIGGQEVLKLRDSVLPLMRLQKIFNVAPSERSRVACYVVVVGVAEKRVGLVVSRLLGQQEVAI
KSLGKYLANLPGIAGSTILGDGRVTLIIDPAGLMENSDGSGGGRIAA
>Mature_606_residues
AIECEDQELLDGFLTETAELLEKLDDDLVALEKTPSDAELMNGIFRSIHTVKGASSFLGFELLVKVTHKTEDVLNRMRRG
ELEVTPEVMDVILEAVDLVKLLVSDIKGGDIVEREIDGTVGKLLPFLSENAKEATVLKPSATTVTPSAPAEAAPTPQATE
TETHPSAELSPAPEAAPVKAPEPAPRVQAPPPPAPRDDKKGDDLADNTTVRVDVKRLDDLMNQVGELVLERNRMMQLNTD
FNDGGDDTFGEEFGKLSKRISFVTSELQMQVLKMRMIPVEKVFKKFPRIVRNLARDLGKEVDLLVFGEETELDRSVVDEI
GDPLIHLIRNAMDHGLETPDERMAAGKPRKGTLILSAAHEGNQIVISIKDDGKGIDPERIARKAKEKGLVTDEQLAAMGQ
REILDLIFLPGFSTKEKATDLSGRGVGMDVVRTNIKKLNGIIDIRSELGQGSEFILKLPLTLAIIQSLLVEVEDETYSIP
LAAVLETLRVEEREFHTIGGQEVLKLRDSVLPLMRLQKIFNVAPSERSRVACYVVVVGVAEKRVGLVVSRLLGQQEVAIK
SLGKYLANLPGIAGSTILGDGRVTLIIDPAGLMENSDGSGGGRIAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=662, Percent_Identity=34.2900302114804, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66132; Mature: 66001

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIECEDQELLDGFLTETAELLEKLDDDLVALEKTPSDAELMNGIFRSIHTVKGASSFLG
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHCHHHHHH
FELLVKVTHKTEDVLNRMRRGELEVTPEVMDVILEAVDLVKLLVSDIKGGDIVEREIDGT
HHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCH
VGKLLPFLSENAKEATVLKPSATTVTPSAPAEAAPTPQATETETHPSAELSPAPEAAPVK
HHHHHHHHHCCCCCCEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APEPAPRVQAPPPPAPRDDKKGDDLADNTTVRVDVKRLDDLMNQVGELVLERNRMMQLNT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEEEEC
DFNDGGDDTFGEEFGKLSKRISFVTSELQMQVLKMRMIPVEKVFKKFPRIVRNLARDLGK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
EVDLLVFGEETELDRSVVDEIGDPLIHLIRNAMDHGLETPDERMAAGKPRKGTLILSAAH
CCEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEECC
EGNQIVISIKDDGKGIDPERIARKAKEKGLVTDEQLAAMGQREILDLIFLPGFSTKEKAT
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHCCCCCCCHHHHC
DLSGRGVGMDVVRTNIKKLNGIIDIRSELGQGSEFILKLPLTLAIIQSLLVEVEDETYSI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCC
PLAAVLETLRVEEREFHTIGGQEVLKLRDSVLPLMRLQKIFNVAPSERSRVACYVVVVGV
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEH
AEKRVGLVVSRLLGQQEVAIKSLGKYLANLPGIAGSTILGDGRVTLIIDPAGLMENSDGS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCHHCCCCCCCC
GGGRIAA
CCCCCCC
>Mature Secondary Structure 
AIECEDQELLDGFLTETAELLEKLDDDLVALEKTPSDAELMNGIFRSIHTVKGASSFLG
CCCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHCHHHHHH
FELLVKVTHKTEDVLNRMRRGELEVTPEVMDVILEAVDLVKLLVSDIKGGDIVEREIDGT
HHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCH
VGKLLPFLSENAKEATVLKPSATTVTPSAPAEAAPTPQATETETHPSAELSPAPEAAPVK
HHHHHHHHHCCCCCCEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APEPAPRVQAPPPPAPRDDKKGDDLADNTTVRVDVKRLDDLMNQVGELVLERNRMMQLNT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEEEEC
DFNDGGDDTFGEEFGKLSKRISFVTSELQMQVLKMRMIPVEKVFKKFPRIVRNLARDLGK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
EVDLLVFGEETELDRSVVDEIGDPLIHLIRNAMDHGLETPDERMAAGKPRKGTLILSAAH
CCEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEECC
EGNQIVISIKDDGKGIDPERIARKAKEKGLVTDEQLAAMGQREILDLIFLPGFSTKEKAT
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHCCCCCCCHHHHC
DLSGRGVGMDVVRTNIKKLNGIIDIRSELGQGSEFILKLPLTLAIIQSLLVEVEDETYSI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCC
PLAAVLETLRVEEREFHTIGGQEVLKLRDSVLPLMRLQKIFNVAPSERSRVACYVVVVGV
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEH
AEKRVGLVVSRLLGQQEVAIKSLGKYLANLPGIAGSTILGDGRVTLIIDPAGLMENSDGS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCHHCCCCCCCC
GGGRIAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]