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The map label for this gene is nadD

Identifier: 78224391

GI number: 78224391

Start: 3601171

End: 3601821

Strand: Direct

Name: nadD

Synonym: Gmet_3200

Alternate gene names: 78224391

Gene position: 3601171-3601821 (Clockwise)

Preceding gene: 78224390

Following gene: 78224392

Centisome position: 90.09

GC content: 63.75

Gene sequence:

>651_bases
ATGAGAACGGGGATTCTCGGCGGCACCTTCAACCCGATCCACCACGCCCACCTCCGCATTGCGGAGGAGGTCCGGGACGC
GTTCGCCCTGGACCAGGTCATCTTCATCCCCGCGGCTTCCCCTCCCCACAAACCCATGGAGGGAGAGATCCCATTCGAGG
TCCGCTGCGAGATGGTCCGCCTTGCCACGGCGGACAACCCCTCCTTCGCCGTCTCCGACTTGGAAGGAAGGCGGACGGGA
AAATCCTACTCCATCGACACCCTGCGGGAGTTGCGGCGGGAGCGCCCCGGGGACGAGTTCTTCTTCATCATCGGCAGCGA
CTCCTTCCTGGACTTCGGCTCCTGGCACGAGTACGAAGCCATCTTCTCTTCGTGCAACATCGTGGCGGTGGAGCGCCCCG
GCGCCGTTATCCGCGACCTGGCGGCGGCCATCCCCGTTGCGGTGGCGCCGCAGTTTTGCTATCATGCCGCCGAAAAACGC
CTCGCCCACCGCTCGGGATACTCGGTCTACTACCTGGCCGGCATCCCCCTGGACATCTCATCAAGCGCCATCCGCAGACT
CGCCCGTCTGGGCCGTTCCATCAGGTACCTGGTGCCGGAGCCGGTCGCGCATTACATCACGGAACAAAGGATTTACACCC
ATGACCGATAA

Upstream 100 bases:

>100_bases
CCCATGGGACTTGAGGATCTGACGACCACCAAGTTCATCGTCTACGGCGACGGCCAGGTAAGGCAGTGACCAGGGACCAG
GGACCAGAGACCGGCAAAGC

Downstream 100 bases:

>100_bases
ACCGACCCTCGCCCCCCTTGAGCGGGCCCTTGAATGCGCCCGCCTCGCCCTCGACAAGAAGGCCCTCGACGTGAAGATCC
TGAAGATCGGCCGTCTTTCG

Product: nicotinate-nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MRTGILGGTFNPIHHAHLRIAEEVRDAFALDQVIFIPAASPPHKPMEGEIPFEVRCEMVRLATADNPSFAVSDLEGRRTG
KSYSIDTLRELRRERPGDEFFFIIGSDSFLDFGSWHEYEAIFSSCNIVAVERPGAVIRDLAAAIPVAVAPQFCYHAAEKR
LAHRSGYSVYYLAGIPLDISSSAIRRLARLGRSIRYLVPEPVAHYITEQRIYTHDR

Sequences:

>Translated_216_residues
MRTGILGGTFNPIHHAHLRIAEEVRDAFALDQVIFIPAASPPHKPMEGEIPFEVRCEMVRLATADNPSFAVSDLEGRRTG
KSYSIDTLRELRRERPGDEFFFIIGSDSFLDFGSWHEYEAIFSSCNIVAVERPGAVIRDLAAAIPVAVAPQFCYHAAEKR
LAHRSGYSVYYLAGIPLDISSSAIRRLARLGRSIRYLVPEPVAHYITEQRIYTHDR
>Mature_216_residues
MRTGILGGTFNPIHHAHLRIAEEVRDAFALDQVIFIPAASPPHKPMEGEIPFEVRCEMVRLATADNPSFAVSDLEGRRTG
KSYSIDTLRELRRERPGDEFFFIIGSDSFLDFGSWHEYEAIFSSCNIVAVERPGAVIRDLAAAIPVAVAPQFCYHAAEKR
LAHRSGYSVYYLAGIPLDISSSAIRRLARLGRSIRYLVPEPVAHYITEQRIYTHDR

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=217, Percent_Identity=35.0230414746544, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_GEOMG (Q39QR1)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386138.1
- ProteinModelPortal:   Q39QR1
- STRING:   Q39QR1
- GeneID:   3741110
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3200
- NMPDR:   fig|269799.3.peg.2434
- eggNOG:   COG1057
- HOGENOM:   HBG739448
- OMA:   LLGWDAF
- PhylomeDB:   Q39QR1
- ProtClustDB:   CLSK829162
- BioCyc:   GMET269799:GMET_3200-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 24300; Mature: 24300

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTGILGGTFNPIHHAHLRIAEEVRDAFALDQVIFIPAASPPHKPMEGEIPFEVRCEMVR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHEEEE
LATADNPSFAVSDLEGRRTGKSYSIDTLRELRRERPGDEFFFIIGSDSFLDFGSWHEYEA
EEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHH
IFSSCNIVAVERPGAVIRDLAAAIPVAVAPQFCYHAAEKRLAHRSGYSVYYLAGIPLDIS
HHCCCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SSAIRRLARLGRSIRYLVPEPVAHYITEQRIYTHDR
HHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRTGILGGTFNPIHHAHLRIAEEVRDAFALDQVIFIPAASPPHKPMEGEIPFEVRCEMVR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHEEEE
LATADNPSFAVSDLEGRRTGKSYSIDTLRELRRERPGDEFFFIIGSDSFLDFGSWHEYEA
EEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHH
IFSSCNIVAVERPGAVIRDLAAAIPVAVAPQFCYHAAEKRLAHRSGYSVYYLAGIPLDIS
HHCCCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SSAIRRLARLGRSIRYLVPEPVAHYITEQRIYTHDR
HHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA