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The map label for this gene is obgE

Identifier: 78224388

GI number: 78224388

Start: 3597639

End: 3598655

Strand: Direct

Name: obgE

Synonym: Gmet_3197

Alternate gene names: 78224388

Gene position: 3597639-3598655 (Clockwise)

Preceding gene: 78224387

Following gene: 78224389

Centisome position: 90.0

GC content: 64.6

Gene sequence:

>1017_bases
ATGCAGTTTATCGATGAAGTAAAAATCCACGTACAGTCGGGGCACGGCGGCGCTGGGTGCGTCTCCTTCCGCCGGGAGAA
GTTCATCCCCTTTGGCGGCCCCGACGGCGGAGACGGCGGCAAGGGTGGCGACGTGATCTTCACCGTCGACCCGAACCTCT
CCACGCTCATGGACCTCCGCTACCGCCCCCACCTGAAGGCGGGGCGGGGGAAAAACGGCATGGGGAAGGACCGCCACGGC
GCCAACGGCGATGACCTCACCATCCCTGTCCCCCCCGGGACCATCGTGAAAGACGCGGAGACCGGGGAAATCCTTGCGGA
CCTGACCGAGCCGGGACAGACCGTAGTCCTCCTCAAGGGGGGGCGCGGTGGCCAGGGGAACGCCCGCTTCACCACCTCCA
CCAACCGCGCACCCAAGTTCGCCCAGCCGGGTGAGGACGAGGAGGAGCGTTGGCTGCGGCTGGAGTTGAAGCTCATGGCC
GATGTGGGACTCCTGGGATTCCCCAACGTGGGGAAGTCGTCGTTCATCACCAAGGTTTCCGCGGCCCGGCCCAAGATCGC
CGACTACCCCTTCACGACCATCAAGCCGAATCTGGGGGTAGTTTCCTACAAGAACTACCGTTCCTTCGTCGTGGCCGACA
TCCCCGGCATCATCGAGGGGGCGTCCGAGGGGGCGGGACTGGGGCACCGGTTCCTCAAGCACGTGGAGCGGACCAACATT
CTCCTTCACCTCATCGATCTCTCCTGGATCCCCGATCGAGACCCGATCCGGGAGTACGAGACCCTCAACCGGGAACTGGC
CCTCTTCAGCCCCGAGCTGGCCGGCAAGGAACAGATCGCCGTCATCAACAAGATCGACCTCCCGGTGGTTCGCGAGAACC
TCCCATCGGTCATCGACTGGTTCAAGGAGCGGGGGATTGCGGTGTTTCCCATCTCCGCCGCCACCGGCGAGGGAATCCCG
ACCCTCCTCGACGAAATCGCCCGGCATCTCTGGGGCCAGGCCGAGGAAGAGTGGTAG

Upstream 100 bases:

>100_bases
CGGCCAGCTAACGCGTTGGCGGGTCGCACAAACCCAAGAGCCTGGGACTTTCGAGTTCCGGGCTTTTGTTGTTTCTTGAA
ACAGGATACGAGATACGACG

Downstream 100 bases:

>100_bases
CGTGGTACCAATGCGCACAGCCATCCTCAAAAAGGTCAAACGGATCGTCATCAAGATCGGGAGCCGTGTCCTCACCGGCG
ACGAGAACGGCCTCAACCAC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPDGGDGGKGGDVIFTVDPNLSTLMDLRYRPHLKAGRGKNGMGKDRHG
ANGDDLTIPVPPGTIVKDAETGEILADLTEPGQTVVLLKGGRGGQGNARFTTSTNRAPKFAQPGEDEEERWLRLELKLMA
DVGLLGFPNVGKSSFITKVSAARPKIADYPFTTIKPNLGVVSYKNYRSFVVADIPGIIEGASEGAGLGHRFLKHVERTNI
LLHLIDLSWIPDRDPIREYETLNRELALFSPELAGKEQIAVINKIDLPVVRENLPSVIDWFKERGIAVFPISAATGEGIP
TLLDEIARHLWGQAEEEW

Sequences:

>Translated_338_residues
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPDGGDGGKGGDVIFTVDPNLSTLMDLRYRPHLKAGRGKNGMGKDRHG
ANGDDLTIPVPPGTIVKDAETGEILADLTEPGQTVVLLKGGRGGQGNARFTTSTNRAPKFAQPGEDEEERWLRLELKLMA
DVGLLGFPNVGKSSFITKVSAARPKIADYPFTTIKPNLGVVSYKNYRSFVVADIPGIIEGASEGAGLGHRFLKHVERTNI
LLHLIDLSWIPDRDPIREYETLNRELALFSPELAGKEQIAVINKIDLPVVRENLPSVIDWFKERGIAVFPISAATGEGIP
TLLDEIARHLWGQAEEEW
>Mature_338_residues
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPDGGDGGKGGDVIFTVDPNLSTLMDLRYRPHLKAGRGKNGMGKDRHG
ANGDDLTIPVPPGTIVKDAETGEILADLTEPGQTVVLLKGGRGGQGNARFTTSTNRAPKFAQPGEDEEERWLRLELKLMA
DVGLLGFPNVGKSSFITKVSAARPKIADYPFTTIKPNLGVVSYKNYRSFVVADIPGIIEGASEGAGLGHRFLKHVERTNI
LLHLIDLSWIPDRDPIREYETLNRELALFSPELAGKEQIAVINKIDLPVVRENLPSVIDWFKERGIAVFPISAATGEGIP
TLLDEIARHLWGQAEEEW

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=42.9906542056075, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI111955139, Length=362, Percent_Identity=36.7403314917127, Blast_Score=188, Evalue=5e-48,
Organism=Homo sapiens, GI111955063, Length=195, Percent_Identity=40, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI58761500, Length=153, Percent_Identity=31.3725490196078, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4557537, Length=87, Percent_Identity=36.7816091954023, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4758796, Length=88, Percent_Identity=36.3636363636364, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789574, Length=331, Percent_Identity=52.5679758308157, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1787454, Length=130, Percent_Identity=31.5384615384615, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=38.6018237082067, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=305, Percent_Identity=32.4590163934426, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.9375, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25145600, Length=184, Percent_Identity=31.5217391304348, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25145602, Length=184, Percent_Identity=31.5217391304348, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=87, Percent_Identity=37.9310344827586, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=101, Percent_Identity=33.6633663366337, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=183, Percent_Identity=42.6229508196721, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=108, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321612, Length=87, Percent_Identity=39.0804597701149, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319499, Length=141, Percent_Identity=36.1702127659575, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=330, Percent_Identity=39.3939393939394, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24585318, Length=360, Percent_Identity=33.0555555555556, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356473, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_GEOMG (Q39QR4)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386135.1
- HSSP:   Q5SJ29
- ProteinModelPortal:   Q39QR4
- SMR:   Q39QR4
- STRING:   Q39QR4
- GeneID:   3741107
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3197
- NMPDR:   fig|269799.3.peg.2431
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- PhylomeDB:   Q39QR4
- ProtClustDB:   PRK12299
- BioCyc:   GMET269799:GMET_3197-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36890; Mature: 36890

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPDGGDGGKGGDVIFTVDPNLSTLMDLR
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
YRPHLKAGRGKNGMGKDRHGANGDDLTIPVPPGTIVKDAETGEILADLTEPGQTVVLLKG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCHHHEECCCCCCEEEEEEC
GRGGQGNARFTTSTNRAPKFAQPGEDEEERWLRLELKLMADVGLLGFPNVGKSSFITKVS
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHH
AARPKIADYPFTTIKPNLGVVSYKNYRSFVVADIPGIIEGASEGAGLGHRFLKHVERTNI
HCCCCCCCCCCEEECCCCCEEEECCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHCE
LLHLIDLSWIPDRDPIREYETLNRELALFSPELAGKEQIAVINKIDLPVVRENLPSVIDW
EEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
FKERGIAVFPISAATGEGIPTLLDEIARHLWGQAEEEW
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPDGGDGGKGGDVIFTVDPNLSTLMDLR
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
YRPHLKAGRGKNGMGKDRHGANGDDLTIPVPPGTIVKDAETGEILADLTEPGQTVVLLKG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCHHHEECCCCCCEEEEEEC
GRGGQGNARFTTSTNRAPKFAQPGEDEEERWLRLELKLMADVGLLGFPNVGKSSFITKVS
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHH
AARPKIADYPFTTIKPNLGVVSYKNYRSFVVADIPGIIEGASEGAGLGHRFLKHVERTNI
HCCCCCCCCCCEEECCCCCEEEECCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHCE
LLHLIDLSWIPDRDPIREYETLNRELALFSPELAGKEQIAVINKIDLPVVRENLPSVIDW
EEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
FKERGIAVFPISAATGEGIPTLLDEIARHLWGQAEEEW
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA