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The map label for this gene is hypA

Identifier: 78224347

GI number: 78224347

Start: 3551732

End: 3552064

Strand: Reverse

Name: hypA

Synonym: Gmet_3156

Alternate gene names: 78224347

Gene position: 3552064-3551732 (Counterclockwise)

Preceding gene: 78224354

Following gene: 78224346

Centisome position: 88.86

GC content: 64.86

Gene sequence:

>333_bases
ATGCACGAGATGTCCATAACCCAGAGCGTGGTGGAGATCTGCGAGAAGAGTGCCGGGGGGCGGCGGGTCCTGGCGGTGAC
CCTGGAGATCGGCGACCTCTCCGGCGTGGTCCCCGATGCGATCGAGTTCTGCTTCGAGGCCTGCACGCGGGATACGCTCC
TGGAGGGTGCCCGGCTCGTCATCGAGCGGGTGCCGGGTCGTGGGGAATGCACCTCCTGCGGAAAGGAATTTCCGGTTCGT
GGCTACTTCGACCCCTGTCCAGCCTGTGGCGCCTACGGCATGAGAGTTGTGTCGGGGGAGGAGCTGCGGGTGAAGGAGTT
GGAGGTGGAGTAA

Upstream 100 bases:

>100_bases
TAAGGAAGTATATCCCTTTCTTTCCTCGGAGAGGCGGCTCTGCTATCATGCCCGTTCAAGCACAAACGGCCCTCGGGGCT
TTGCGGAAGGGGAGATGCAG

Downstream 100 bases:

>100_bases
CCGCCGATATTTTCTCTTGCCTGACCTGGTGGCGTCGCTGGTTTTGTGGTGTACAATAGTGTTTTACAAAGCCAGGCAAA
TCAATTAGAGTCCAGTTTTA

Product: hydrogenase expression/synthesis, HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MHEMSITQSVVEICEKSAGGRRVLAVTLEIGDLSGVVPDAIEFCFEACTRDTLLEGARLVIERVPGRGECTSCGKEFPVR
GYFDPCPACGAYGMRVVSGEELRVKELEVE

Sequences:

>Translated_110_residues
MHEMSITQSVVEICEKSAGGRRVLAVTLEIGDLSGVVPDAIEFCFEACTRDTLLEGARLVIERVPGRGECTSCGKEFPVR
GYFDPCPACGAYGMRVVSGEELRVKELEVE
>Mature_110_residues
MHEMSITQSVVEICEKSAGGRRVLAVTLEIGDLSGVVPDAIEFCFEACTRDTLLEGARLVIERVPGRGECTSCGKEFPVR
GYFDPCPACGAYGMRVVSGEELRVKELEVE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=38.9380530973451, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_GEOMG (Q39QV5)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386094.1
- STRING:   Q39QV5
- GeneID:   3741125
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3156
- NMPDR:   fig|269799.3.peg.2391
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   IAGNEFF
- PhylomeDB:   Q39QV5
- ProtClustDB:   CLSK827786
- BioCyc:   GMET269799:GMET_3156-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 11957; Mature: 11957

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
6.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMSITQSVVEICEKSAGGRRVLAVTLEIGDLSGVVPDAIEFCFEACTRDTLLEGARLV
CCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IERVPGRGECTSCGKEFPVRGYFDPCPACGAYGMRVVSGEELRVKELEVE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCC
>Mature Secondary Structure
MHEMSITQSVVEICEKSAGGRRVLAVTLEIGDLSGVVPDAIEFCFEACTRDTLLEGARLV
CCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IERVPGRGECTSCGKEFPVRGYFDPCPACGAYGMRVVSGEELRVKELEVE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA