| Definition | Geobacter metallireducens GS-15 chromosome, complete genome. |
|---|---|
| Accession | NC_007517 |
| Length | 3,997,420 |
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The map label for this gene is polA [H]
Identifier: 78224176
GI number: 78224176
Start: 3369686
End: 3372364
Strand: Reverse
Name: polA [H]
Synonym: Gmet_2983
Alternate gene names: 78224176
Gene position: 3372364-3369686 (Counterclockwise)
Preceding gene: 78224177
Following gene: 78224175
Centisome position: 84.36
GC content: 65.06
Gene sequence:
>2679_bases ATGACCGGGAAACAGACCCTCTACCTCATCGACGGCTCCTCCTATATCTACCGGGCCTACTACGCCATCCGGCACCTCTC GTCCCCCAAGGGGTTCCCCACTAACGCCCTCTACGGTTTCACCCAGATGCTCCTCAAGGTCATCAAGGACCGCCGCCCCG ACCATATCGCCGTGGTCTTCGACGTGGGGCGCACTACCTTTCGCACCGACCTCTACCCCGACTACAAGGCCAACCGCTCC GCCATGCCCGACGATCTCGTCCCCCAGATCGCCCCCATCAAGGAGATGGTCCGGGCCTTCAATATCCCGGTGCTGGAGCT GGCGGGGTACGAGGCCGACGACATCATCGGCACCATCGCCCGGGAGTGCGAGGAGCGTGGGATGGAGGCGGTGGTGGTCA CCGGCGACAAGGACCTGATGCAGATCGTGAGCGAGCGGGTCACGCTCCTCGACACCATGAAGGAGAAGGCCTCGGGCATC CCCGACGTGCAGGAGCGGTTCGGCGTCGGGCCGGAAGGGGTGATCGACATCCTCGGCCTCGCCGGTGACACCTCCGACAA CATCCCCGGCGTTCCCGGCATCGGCGAGAAGACCGCCATCAAACTGATCCAGGAGTTCGGCTCCCTGGACACGCTTCTGG AGCGGGCTGGCGAGGTGAAAGGAAAGACCGGGGAGAAGCTCCGGGAGTTTGCCGACCAGGCCCGCCTCTCCCGGCAGTTG GCCACCATCGTGCGGGACGTGCCGATGGCGTTTGATTTTGCCGCCTTTGCCGCCTCTTCCCCCGACAACCGGCGTCTGGC CGAGCTCATCAAGGAGTACGGCTTCACCACCCTCATGAAGGAGCTGACCAGCGAGGCGACCCTCTCCACCGAGCAGTACC GGACCGTCGCCACCGAGGAGGAATTTGAGGCGCTTCTTGCAGATTTGAAAGCCGCCGGCACCTTTGCCGTGGACCTGGAG ACCACGAGCCTGAACCCCCTGGAGGCGGAGATCGTCGGCATTTCACTCAGCTACCGGGACCACGAGGCGTGCTACATCCC GGTGGGGCACTTCTATCTGGGGGCGCCGGAGCAGCTCCCCCGCCGGCGGGTGCTGGACGCCCTGACGCCCCTCCTCATCG ACCCGAAAATCCGCAAGGTGGGGCAGAACCTGAAGTACGACTACCAGGTCTTCCGGCGCCACGGCATCGAGCTTGGCGGG GTCTGGTGCGACACCATGGTGGCCTCCTACCTCCTGAACCCGGTCCGCTCCGGCCACGGCCTCGACTCCCTGGCCGTGGA GCATCTGGATCACAAGATGATCTCCTACGAGGAGGTGGCGGGAAAGGGGAAGGAGCAGGTGAACTTCGCCCAGGTGCCGG TGGAGAAAGCCTCCACCTATTCCTGCGAGGACTCGGACGCCGCGTGGCTCCTCCACCGTCTCTTCCTCCCCCGGGTGGCG GTGTGGGGGATGGAGCGGCTCTTTTTTGATGTGGAGATGCCCCTGGTGCCGATCCTGGCCGAGATGGAGCTGGCCGGGGT AAAGCTGGACCTCCCCCTTCTCGGGGAACTATCCGCCGGTTTCGGGAAACAGCTGGCGGAACTGGAGGGGCGGATCACGG GGCTCGCTCCGGAGCCCTTCAATCTCAACTCCCCCAAGCAGCTCGGGGAGGTGCTCTTCGAGAAGCTGAAGCTCCCCACC GGTAAGAAGACCAAGACCAAGACCGGTTGGTCCACCAACGTGGAGGAACTGGAGCGGCTGGCCGAGGCCGGCCACGAGAT CGCGGCCCTCATCCTCCAGTACCGGGGGCTCGCCAAACTCAAATCCACCTATACCGACGCCCTCCCCAAGCTGGTGCAGC CAGCCACGGGAAGGGTCCATACCTCCTACAACCAGACCGTCACCAACACGGGGCGGCTCTCCTCGTCGGAGCCGAACCTG CAGAACATCCCGGTCCGGACCGAGGAGGGGCGACGGATCCGCCGGGCTTTCATCGCCGAGGAGGGGCACCTGCTCCTCTC CGCCGACTACTCCCAGATCGAGCTCCGGGTCCTGGCCCATTTCTCGGAGGACCGGGTCTTCTGTGACGCCTTTGCCAAAG ACGAGGACATCCACACCCGCACCGCCGCCGAGGTCTTCGGCCTCTTCCCCGAGATGGTGACCCCCGAGATGCGGCGCCAG GCCAAGGCCATCAACTTCGGGGTCATCTACGGCCAGGGGGCCTTCAGTCTCGCCAAGCAGCTCGGCATCGCAACAAAAGT GGCCAGGGAGTTCATCGACAACTACTTCGCCCGCCATCCCGGTGCCCGGGCGTTCCTGGACGGCTGCGTGCGGGAGGCGG AGGAGAAGGGGCATGTGACCACGCTCCTTGGGCGCAGGCTCCCGATTCCCGACATCAAGAGCGCCAACGGTAACATCCGG GCCTTTGCCCAGCGCAACGCCGTCAACTACCCCATCCAGGGGTCCGCCGCCGACATCATCAAGGAGGCCATGGTGAAGGT GACGGCCCGGATGCGGCGCGACGTCGTGGGGAGCCGGCTCATCATGCAGGTCCACGACGAACTCGTCTTCGAGGTGCCCA AGGGCGAGGTGGTTGCCATGGAACAGCTCGTGCGGCGCGAGATGGAGCACGCCGTGAGCCTGCGCGTGCCGCTTAAAGTG GATATAAACCACGGCGGGAACTGGAGCGAGGCCCACTAG
Upstream 100 bases:
>100_bases GGTGGCGGTTCGACGGGATGCAGTTCGCCATGCGGGATGCGAGCCGGCGCCCCGCCATGGCCTTTGTCTTTTTCACGCGG GAGGAACGGGAGGTGGCGCC
Downstream 100 bases:
>100_bases GCCATGCCGGAGTCCGGCAGGGGCAAACGGGGATTGATGCTTATTCTATAGATGGGTTTTATTAAGAATAACTGCGTGGA ATTGCGGGCGTCTTTCGTGA
Product: DNA polymerase I
Products: NA
Alternate protein names: POL I [H]
Number of amino acids: Translated: 892; Mature: 891
Protein sequence:
>892_residues MTGKQTLYLIDGSSYIYRAYYAIRHLSSPKGFPTNALYGFTQMLLKVIKDRRPDHIAVVFDVGRTTFRTDLYPDYKANRS AMPDDLVPQIAPIKEMVRAFNIPVLELAGYEADDIIGTIARECEERGMEAVVVTGDKDLMQIVSERVTLLDTMKEKASGI PDVQERFGVGPEGVIDILGLAGDTSDNIPGVPGIGEKTAIKLIQEFGSLDTLLERAGEVKGKTGEKLREFADQARLSRQL ATIVRDVPMAFDFAAFAASSPDNRRLAELIKEYGFTTLMKELTSEATLSTEQYRTVATEEEFEALLADLKAAGTFAVDLE TTSLNPLEAEIVGISLSYRDHEACYIPVGHFYLGAPEQLPRRRVLDALTPLLIDPKIRKVGQNLKYDYQVFRRHGIELGG VWCDTMVASYLLNPVRSGHGLDSLAVEHLDHKMISYEEVAGKGKEQVNFAQVPVEKASTYSCEDSDAAWLLHRLFLPRVA VWGMERLFFDVEMPLVPILAEMELAGVKLDLPLLGELSAGFGKQLAELEGRITGLAPEPFNLNSPKQLGEVLFEKLKLPT GKKTKTKTGWSTNVEELERLAEAGHEIAALILQYRGLAKLKSTYTDALPKLVQPATGRVHTSYNQTVTNTGRLSSSEPNL QNIPVRTEEGRRIRRAFIAEEGHLLLSADYSQIELRVLAHFSEDRVFCDAFAKDEDIHTRTAAEVFGLFPEMVTPEMRRQ AKAINFGVIYGQGAFSLAKQLGIATKVAREFIDNYFARHPGARAFLDGCVREAEEKGHVTTLLGRRLPIPDIKSANGNIR AFAQRNAVNYPIQGSAADIIKEAMVKVTARMRRDVVGSRLIMQVHDELVFEVPKGEVVAMEQLVRREMEHAVSLRVPLKV DINHGGNWSEAH
Sequences:
>Translated_892_residues MTGKQTLYLIDGSSYIYRAYYAIRHLSSPKGFPTNALYGFTQMLLKVIKDRRPDHIAVVFDVGRTTFRTDLYPDYKANRS AMPDDLVPQIAPIKEMVRAFNIPVLELAGYEADDIIGTIARECEERGMEAVVVTGDKDLMQIVSERVTLLDTMKEKASGI PDVQERFGVGPEGVIDILGLAGDTSDNIPGVPGIGEKTAIKLIQEFGSLDTLLERAGEVKGKTGEKLREFADQARLSRQL ATIVRDVPMAFDFAAFAASSPDNRRLAELIKEYGFTTLMKELTSEATLSTEQYRTVATEEEFEALLADLKAAGTFAVDLE TTSLNPLEAEIVGISLSYRDHEACYIPVGHFYLGAPEQLPRRRVLDALTPLLIDPKIRKVGQNLKYDYQVFRRHGIELGG VWCDTMVASYLLNPVRSGHGLDSLAVEHLDHKMISYEEVAGKGKEQVNFAQVPVEKASTYSCEDSDAAWLLHRLFLPRVA VWGMERLFFDVEMPLVPILAEMELAGVKLDLPLLGELSAGFGKQLAELEGRITGLAPEPFNLNSPKQLGEVLFEKLKLPT GKKTKTKTGWSTNVEELERLAEAGHEIAALILQYRGLAKLKSTYTDALPKLVQPATGRVHTSYNQTVTNTGRLSSSEPNL QNIPVRTEEGRRIRRAFIAEEGHLLLSADYSQIELRVLAHFSEDRVFCDAFAKDEDIHTRTAAEVFGLFPEMVTPEMRRQ AKAINFGVIYGQGAFSLAKQLGIATKVAREFIDNYFARHPGARAFLDGCVREAEEKGHVTTLLGRRLPIPDIKSANGNIR AFAQRNAVNYPIQGSAADIIKEAMVKVTARMRRDVVGSRLIMQVHDELVFEVPKGEVVAMEQLVRREMEHAVSLRVPLKV DINHGGNWSEAH >Mature_891_residues TGKQTLYLIDGSSYIYRAYYAIRHLSSPKGFPTNALYGFTQMLLKVIKDRRPDHIAVVFDVGRTTFRTDLYPDYKANRSA MPDDLVPQIAPIKEMVRAFNIPVLELAGYEADDIIGTIARECEERGMEAVVVTGDKDLMQIVSERVTLLDTMKEKASGIP DVQERFGVGPEGVIDILGLAGDTSDNIPGVPGIGEKTAIKLIQEFGSLDTLLERAGEVKGKTGEKLREFADQARLSRQLA TIVRDVPMAFDFAAFAASSPDNRRLAELIKEYGFTTLMKELTSEATLSTEQYRTVATEEEFEALLADLKAAGTFAVDLET TSLNPLEAEIVGISLSYRDHEACYIPVGHFYLGAPEQLPRRRVLDALTPLLIDPKIRKVGQNLKYDYQVFRRHGIELGGV WCDTMVASYLLNPVRSGHGLDSLAVEHLDHKMISYEEVAGKGKEQVNFAQVPVEKASTYSCEDSDAAWLLHRLFLPRVAV WGMERLFFDVEMPLVPILAEMELAGVKLDLPLLGELSAGFGKQLAELEGRITGLAPEPFNLNSPKQLGEVLFEKLKLPTG KKTKTKTGWSTNVEELERLAEAGHEIAALILQYRGLAKLKSTYTDALPKLVQPATGRVHTSYNQTVTNTGRLSSSEPNLQ NIPVRTEEGRRIRRAFIAEEGHLLLSADYSQIELRVLAHFSEDRVFCDAFAKDEDIHTRTAAEVFGLFPEMVTPEMRRQA KAINFGVIYGQGAFSLAKQLGIATKVAREFIDNYFARHPGARAFLDGCVREAEEKGHVTTLLGRRLPIPDIKSANGNIRA FAQRNAVNYPIQGSAADIIKEAMVKVTARMRRDVVGSRLIMQVHDELVFEVPKGEVVAMEQLVRREMEHAVSLRVPLKVD INHGGNWSEAH
Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template [H]
COG id: COG0749
COG function: function code L; DNA polymerase I - 3'-5' exonuclease and polymerase domains
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 5'-3' exonuclease domain [H]
Homologues:
Organism=Homo sapiens, GI112420958, Length=515, Percent_Identity=31.8446601941748, Blast_Score=244, Evalue=4e-64, Organism=Homo sapiens, GI139394648, Length=271, Percent_Identity=38.0073800738007, Blast_Score=178, Evalue=2e-44, Organism=Escherichia coli, GI1790294, Length=925, Percent_Identity=47.3513513513513, Blast_Score=789, Evalue=0.0, Organism=Escherichia coli, GI226510970, Length=234, Percent_Identity=31.6239316239316, Blast_Score=120, Evalue=4e-28, Organism=Caenorhabditis elegans, GI86563272, Length=409, Percent_Identity=32.518337408313, Blast_Score=197, Evalue=2e-50, Organism=Drosophila melanogaster, GI17933644, Length=589, Percent_Identity=29.2020373514431, Blast_Score=205, Evalue=1e-52,
Paralogues:
None
Copy number: 400 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002562 - InterPro: IPR020046 - InterPro: IPR020045 - InterPro: IPR002421 - InterPro: IPR020047 - InterPro: IPR019760 - InterPro: IPR001098 - InterPro: IPR018320 - InterPro: IPR002298 - InterPro: IPR008918 - InterPro: IPR003583 - InterPro: IPR012337 [H]
Pfam domain/function: PF01612 3_5_exonuc; PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 99143; Mature: 99012
Theoretical pI: Translated: 5.96; Mature: 5.96
Prosite motif: PS00447 DNA_POLYMERASE_A
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTGKQTLYLIDGSSYIYRAYYAIRHLSSPKGFPTNALYGFTQMLLKVIKDRRPDHIAVVF CCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE DVGRTTFRTDLYPDYKANRSAMPDDLVPQIAPIKEMVRAFNIPVLELAGYEADDIIGTIA ECCCCEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH RECEERGMEAVVVTGDKDLMQIVSERVTLLDTMKEKASGIPDVQERFGVGPEGVIDILGL HHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHC AGDTSDNIPGVPGIGEKTAIKLIQEFGSLDTLLERAGEVKGKTGEKLREFADQARLSRQL CCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH ATIVRDVPMAFDFAAFAASSPDNRRLAELIKEYGFTTLMKELTSEATLSTEQYRTVATEE HHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHCCHH EFEALLADLKAAGTFAVDLETTSLNPLEAEIVGISLSYRDHEACYIPVGHFYLGAPEQLP HHHHHHHHHHHCCEEEEEEECCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCHHHHH RRRVLDALTPLLIDPKIRKVGQNLKYDYQVFRRHGIELGGVWCDTMVASYLLNPVRSGHG HHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC LDSLAVEHLDHKMISYEEVAGKGKEQVNFAQVPVEKASTYSCEDSDAAWLLHRLFLPRVA HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHH VWGMERLFFDVEMPLVPILAEMELAGVKLDLPLLGELSAGFGKQLAELEGRITGLAPEPF HHHHHHHHEECCCCHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCCEECCCCCCC NLNSPKQLGEVLFEKLKLPTGKKTKTKTGWSTNVEELERLAEAGHEIAALILQYRGLAKL CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH KSTYTDALPKLVQPATGRVHTSYNQTVTNTGRLSSSEPNLQNIPVRTEEGRRIRRAFIAE HHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC EGHLLLSADYSQIELRVLAHFSEDRVFCDAFAKDEDIHTRTAAEVFGLFPEMVTPEMRRQ CCCEEEECCCHHHEEHHEECCCCCCEEEHHHCCCCCHHHHHHHHHHHHCHHHCCHHHHHH AKAINFGVIYGQGAFSLAKQLGIATKVAREFIDNYFARHPGARAFLDGCVREAEEKGHVT HHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCH TLLGRRLPIPDIKSANGNIRAFAQRNAVNYPIQGSAADIIKEAMVKVTARMRRDVVGSRL HHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH IMQVHDELVFEVPKGEVVAMEQLVRREMEHAVSLRVPLKVDINHGGNWSEAH HHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHEEECEEEEEECCCCCCCCCC >Mature Secondary Structure TGKQTLYLIDGSSYIYRAYYAIRHLSSPKGFPTNALYGFTQMLLKVIKDRRPDHIAVVF CCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE DVGRTTFRTDLYPDYKANRSAMPDDLVPQIAPIKEMVRAFNIPVLELAGYEADDIIGTIA ECCCCEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH RECEERGMEAVVVTGDKDLMQIVSERVTLLDTMKEKASGIPDVQERFGVGPEGVIDILGL HHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHC AGDTSDNIPGVPGIGEKTAIKLIQEFGSLDTLLERAGEVKGKTGEKLREFADQARLSRQL CCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH ATIVRDVPMAFDFAAFAASSPDNRRLAELIKEYGFTTLMKELTSEATLSTEQYRTVATEE HHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHCCHH EFEALLADLKAAGTFAVDLETTSLNPLEAEIVGISLSYRDHEACYIPVGHFYLGAPEQLP HHHHHHHHHHHCCEEEEEEECCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCHHHHH RRRVLDALTPLLIDPKIRKVGQNLKYDYQVFRRHGIELGGVWCDTMVASYLLNPVRSGHG HHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC LDSLAVEHLDHKMISYEEVAGKGKEQVNFAQVPVEKASTYSCEDSDAAWLLHRLFLPRVA HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHH VWGMERLFFDVEMPLVPILAEMELAGVKLDLPLLGELSAGFGKQLAELEGRITGLAPEPF HHHHHHHHEECCCCHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCCEECCCCCCC NLNSPKQLGEVLFEKLKLPTGKKTKTKTGWSTNVEELERLAEAGHEIAALILQYRGLAKL CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH KSTYTDALPKLVQPATGRVHTSYNQTVTNTGRLSSSEPNLQNIPVRTEEGRRIRRAFIAE HHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC EGHLLLSADYSQIELRVLAHFSEDRVFCDAFAKDEDIHTRTAAEVFGLFPEMVTPEMRRQ CCCEEEECCCHHHEEHHEECCCCCCEEEHHHCCCCCHHHHHHHHHHHHCHHHCCHHHHHH AKAINFGVIYGQGAFSLAKQLGIATKVAREFIDNYFARHPGARAFLDGCVREAEEKGHVT HHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCH TLLGRRLPIPDIKSANGNIRAFAQRNAVNYPIQGSAADIIKEAMVKVTARMRRDVVGSRL HHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH IMQVHDELVFEVPKGEVVAMEQLVRREMEHAVSLRVPLKVDINHGGNWSEAH HHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHEEECEEEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 6276402; 8346018; 9278503; 6183253; 6302278; 7035456; 3883192; 1989886; 8469987; 8260491; 9514742; 9888810; 10588690; 8442659 [H]