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The map label for this gene is hlyB [H]

Identifier: 78224024

GI number: 78224024

Start: 3204285

End: 3205937

Strand: Reverse

Name: hlyB [H]

Synonym: Gmet_2828

Alternate gene names: 78224024

Gene position: 3205937-3204285 (Counterclockwise)

Preceding gene: 78224025

Following gene: 78224023

Centisome position: 80.2

GC content: 63.22

Gene sequence:

>1653_bases
ATGTCGTTCAAACTTACCATCAAGGCCCGAATCGTTTTCATCGTCGCGTTTTTTTCGGCCATGCTTATCGTCTTCGGCAT
GCTGGGGCTGTCGGGGATGAAGGCTGCCAATGAAACCAGCCACGCGCTCCATGGCGAGAACATGAAGAGCGTGCAGGTCC
TCAGCAGGATCGCGGCTCTCATGCGCGACAACCGCATCCAGCTCCTTCTCTCCCTCCAGCATGATTCCAAGAGTGAATTC
AGCGCCCTCCACGACCATCCGCTCACCATGCACACCGACATCGTCGGCAAGAATATCGAGGAGATCACGGCACTCCTGGC
GGAGTATGAGAAACTCCCCAAAACCGAAGAAGACAAGAAACTCGCCGCGGAGTTCGAGACGGCGAGGGAGGCCTTTGTGC
AGGAGGGGCTCATCCCCGTGCGCGAGGCGGTGCTGACCGGGAAATACAAAGACGCCGTGGAACTGACTCTCAAGAAAGTG
AACCCCCTCTTCAAGCCGGCCAATGAAGCGCTGGAAAAAATGATCAAGTCGGAATTTGCCGCGGCAAAGGAGGACTTCGA
GCGGGATGACAAGACCTATCGCACCGACCGGCTTATCATGATTGTCGGGCTTGTTGCATCTATCGCCATTGGGGTGGTAT
TGAGCCTCTTCATCATCCGTTCCCTGCGCCGCAGTTCCGATGAGCTGGCATCCGTTGCCGCTGCGGTCTCCGCGGGAGAC
CTGAGCCGGCGCGCTACCGGGCTCTCCAACGACGAACTGGGGGCCATCGGAGGTTCGTTCAACGAGACCGCCGATTCCTT
TGCCCGGGTCATCGCCGGCATCCGGGGGAACGCGGAACAGGTGGCAACGGCCGCAACCCAGGTCCACAGCAGCGCCGAGC
AGATGGCCACCGGCGTCGAGGAGGTGGCGGCCCAGACCGGAACCGTCGCCACTGCCGGCGAGGAGATGGCGGCCACCGCC
GCGGAGATCGCCCAGAACTGCCAGATGGCTGCCGAAGCTGCCCAACGGGCCACGGAGTCGGCCACCGGCGGAGCCACGGT
GGTCCAGCGGACCGTGAACGGCATGGCGCGGATCGCCGACCGGGTGCGGAGTTCCGCCAAGACTGTCGAGAGTCTCGGGT
CCCGCTCCGAGCAGATCGGTGAAATCATCGGCACCATTCAGGATATTGCCGACCAGACGAACCTCCTGGCCCTGAACGCC
GCCATCGAGGCGGCCCGGGCCGGCGAGCAGGGGCGCGGCTTTGCCGTGGTGGCCGATGAGGTCCGGGCCCTGGCCGAGCG
GACCACGAAAGCGACCCGGGAGATCGGCGAGATGATCAAGGCGATTCAGCAGGAGACGCGGGGGGCGGTTGCCGCCATGG
AGGAGGGGGTCCATGAGGTGGAGGCTGGGACTGCCGATGCCCAACAGTCCGGCGCGGCCCTTCAGGAGATCATGAACCAG
ATCAACGAGCTGGCCATGCAGGTGAGCCAGATAGCCACCGCCGCCGAGCAGCAGACCGCCACCACCGGCGAGATCAGCGG
CAACGTCCAGCAGGTCTCCGAGGTGGTCCAGGAAACCGCCAAGGGTATCCAGGAATCAGCCCAGGCTGCGTCGCGGGTTG
CCGAGTTGGCTGACGAGCTCAATAATCTGGTGGGGCGGTTCAAGGTGGCGTAA

Upstream 100 bases:

>100_bases
TCCGCTCAAGTTATTCGGGAATTCTCCGAAACGAGATGTAAGGACCTCTGCGCGTCGTGTGTGACGGAGCGGGGACCCGA
ATTCAGGGGAGGAAAAGAAT

Downstream 100 bases:

>100_bases
CAGTCGTTCGGACACGAAACAAAGGAGGGGCGACCGCTGATACGGTCGCCCTTTTTTCATATTCACCGCACAAGGAAGTC
AACCCTTCCTTCAAAGTATC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MSFKLTIKARIVFIVAFFSAMLIVFGMLGLSGMKAANETSHALHGENMKSVQVLSRIAALMRDNRIQLLLSLQHDSKSEF
SALHDHPLTMHTDIVGKNIEEITALLAEYEKLPKTEEDKKLAAEFETAREAFVQEGLIPVREAVLTGKYKDAVELTLKKV
NPLFKPANEALEKMIKSEFAAAKEDFERDDKTYRTDRLIMIVGLVASIAIGVVLSLFIIRSLRRSSDELASVAAAVSAGD
LSRRATGLSNDELGAIGGSFNETADSFARVIAGIRGNAEQVATAATQVHSSAEQMATGVEEVAAQTGTVATAGEEMAATA
AEIAQNCQMAAEAAQRATESATGGATVVQRTVNGMARIADRVRSSAKTVESLGSRSEQIGEIIGTIQDIADQTNLLALNA
AIEAARAGEQGRGFAVVADEVRALAERTTKATREIGEMIKAIQQETRGAVAAMEEGVHEVEAGTADAQQSGAALQEIMNQ
INELAMQVSQIATAAEQQTATTGEISGNVQQVSEVVQETAKGIQESAQAASRVAELADELNNLVGRFKVA

Sequences:

>Translated_550_residues
MSFKLTIKARIVFIVAFFSAMLIVFGMLGLSGMKAANETSHALHGENMKSVQVLSRIAALMRDNRIQLLLSLQHDSKSEF
SALHDHPLTMHTDIVGKNIEEITALLAEYEKLPKTEEDKKLAAEFETAREAFVQEGLIPVREAVLTGKYKDAVELTLKKV
NPLFKPANEALEKMIKSEFAAAKEDFERDDKTYRTDRLIMIVGLVASIAIGVVLSLFIIRSLRRSSDELASVAAAVSAGD
LSRRATGLSNDELGAIGGSFNETADSFARVIAGIRGNAEQVATAATQVHSSAEQMATGVEEVAAQTGTVATAGEEMAATA
AEIAQNCQMAAEAAQRATESATGGATVVQRTVNGMARIADRVRSSAKTVESLGSRSEQIGEIIGTIQDIADQTNLLALNA
AIEAARAGEQGRGFAVVADEVRALAERTTKATREIGEMIKAIQQETRGAVAAMEEGVHEVEAGTADAQQSGAALQEIMNQ
INELAMQVSQIATAAEQQTATTGEISGNVQQVSEVVQETAKGIQESAQAASRVAELADELNNLVGRFKVA
>Mature_549_residues
SFKLTIKARIVFIVAFFSAMLIVFGMLGLSGMKAANETSHALHGENMKSVQVLSRIAALMRDNRIQLLLSLQHDSKSEFS
ALHDHPLTMHTDIVGKNIEEITALLAEYEKLPKTEEDKKLAAEFETAREAFVQEGLIPVREAVLTGKYKDAVELTLKKVN
PLFKPANEALEKMIKSEFAAAKEDFERDDKTYRTDRLIMIVGLVASIAIGVVLSLFIIRSLRRSSDELASVAAAVSAGDL
SRRATGLSNDELGAIGGSFNETADSFARVIAGIRGNAEQVATAATQVHSSAEQMATGVEEVAAQTGTVATAGEEMAATAA
EIAQNCQMAAEAAQRATESATGGATVVQRTVNGMARIADRVRSSAKTVESLGSRSEQIGEIIGTIQDIADQTNLLALNAA
IEAARAGEQGRGFAVVADEVRALAERTTKATREIGEMIKAIQQETRGAVAAMEEGVHEVEAGTADAQQSGAALQEIMNQI
NELAMQVSQIATAAEQQTATTGEISGNVQQVSEVVQETAKGIQESAQAASRVAELADELNNLVGRFKVA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=446, Percent_Identity=27.3542600896861, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1788194, Length=390, Percent_Identity=29.2307692307692, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI2367378, Length=528, Percent_Identity=24.2424242424242, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788195, Length=322, Percent_Identity=32.6086956521739, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789453, Length=298, Percent_Identity=27.8523489932886, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58486; Mature: 58355

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKLTIKARIVFIVAFFSAMLIVFGMLGLSGMKAANETSHALHGENMKSVQVLSRIAAL
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHH
MRDNRIQLLLSLQHDSKSEFSALHDHPLTMHTDIVGKNIEEITALLAEYEKLPKTEEDKK
HHCCHHEEEEEECCCCHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHHCCCCCHHHH
LAAEFETAREAFVQEGLIPVREAVLTGKYKDAVELTLKKVNPLFKPANEALEKMIKSEFA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHH
AAKEDFERDDKTYRTDRLIMIVGLVASIAIGVVLSLFIIRSLRRSSDELASVAAAVSAGD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LSRRATGLSNDELGAIGGSFNETADSFARVIAGIRGNAEQVATAATQVHSSAEQMATGVE
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EVAAQTGTVATAGEEMAATAAEIAQNCQMAAEAAQRATESATGGATVVQRTVNGMARIAD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RVRSSAKTVESLGSRSEQIGEIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEHHHHH
VRALAERTTKATREIGEMIKAIQQETRGAVAAMEEGVHEVEAGTADAQQSGAALQEIMNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHH
INELAMQVSQIATAAEQQTATTGEISGNVQQVSEVVQETAKGIQESAQAASRVAELADEL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNLVGRFKVA
HHHHHHHCCC
>Mature Secondary Structure 
SFKLTIKARIVFIVAFFSAMLIVFGMLGLSGMKAANETSHALHGENMKSVQVLSRIAAL
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHH
MRDNRIQLLLSLQHDSKSEFSALHDHPLTMHTDIVGKNIEEITALLAEYEKLPKTEEDKK
HHCCHHEEEEEECCCCHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHHCCCCCHHHH
LAAEFETAREAFVQEGLIPVREAVLTGKYKDAVELTLKKVNPLFKPANEALEKMIKSEFA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHH
AAKEDFERDDKTYRTDRLIMIVGLVASIAIGVVLSLFIIRSLRRSSDELASVAAAVSAGD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LSRRATGLSNDELGAIGGSFNETADSFARVIAGIRGNAEQVATAATQVHSSAEQMATGVE
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EVAAQTGTVATAGEEMAATAAEIAQNCQMAAEAAQRATESATGGATVVQRTVNGMARIAD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RVRSSAKTVESLGSRSEQIGEIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEHHHHH
VRALAERTTKATREIGEMIKAIQQETRGAVAAMEEGVHEVEAGTADAQQSGAALQEIMNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHH
INELAMQVSQIATAAEQQTATTGEISGNVQQVSEVVQETAKGIQESAQAASRVAELADEL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNLVGRFKVA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]