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The map label for this gene is cph2 [H]

Identifier: 78223917

GI number: 78223917

Start: 3073565

End: 3075625

Strand: Direct

Name: cph2 [H]

Synonym: Gmet_2721

Alternate gene names: 78223917

Gene position: 3073565-3075625 (Clockwise)

Preceding gene: 78223916

Following gene: 304570572

Centisome position: 76.89

GC content: 62.4

Gene sequence:

>2061_bases
GTGCACCATGCTGAACTGACTACAATCCAGCCGGTGGAGCTGCTTGAGGTACTCAAATCGTACCCCTTCCTCGCGCCCTA
CCAGCTGACCTTCTGCGCCGAGACAGAAGGGGGAATGCCGCTCTACCGGTCCCTCTTCCCCGTCTGCGAGGCCATCGCCC
AGAGCCTGCTCTGCGGCAAGGCCTGCCAGACGGCCGTGGAAGAGGCAGTCCAGAGGGCCATGGGCGAAAACAGGGCGGTG
GTCTTCCGGTGTCAGACAGGACTCCTCAATTTTGCCGTGCCGCTCCGGGGGAGGGATATCCCCTTCACCTGCCTCATCGG
CGGCGGAGTCAGGGAGAAAGATGTCGACCTGGCCCCCATGGAATCCCTCGCCCAGACAGACAGCGTGGACGCTGTTGCCC
TTCTGGAAGAGTTGGAAAACCTCCCCGCCGTCACCGAGGAGGAGGTGGCCGAAACTGCCCGCAAGATTCACGAACTGCTT
CCGACACTGCTCGGCCGGAACATCCACACCCTCATCTTCGAAAACACCATGCGGCGGCTCGCCTCCATCTCCGGGGTTGC
CGGCGGCATCGACGCGGCAAAGACCGCCGACGAAGTCCTGGGGCTGTTGAGCGAGACCCTCGGCATCCTCTTCGATATCG
GCCGGATCGCCATGCTCTCCCCCGAAGGAAGCAGCACATTCTCCATGAAGGGGCTCTGGGGGATGGAGCCCGACCTGGGA
ACCATGCCGGCGGCACGGGCGTTGTCGATCTTTCCCCGCAACCGGAAAGAGAACGTCGTCACCCTCGACGATGAGTGCCG
GACCCTCTTCCCTGAAATCGCCGCCAATCAGGGGTTGTGCATCCGCTTCGCCTCCAACGGTGATTTTCTCGGCATCATGG
TTCTCTTCGATGCGGCCATCACCCGCCGGGACAAGCTCCTCGTGCAACTGGTCGCCGACCGGGCCTCGGCGAAACTCCTG
CGCCTGCGGGAGGAGGAAAAGCACTCCGCCGACAATGCCCAGGCAACCAAGCTCATGACCATGTTCACCGCCCTCTCCCG
GGCCACCTCCAAGGAAGAGCTCAACGAGCAAATCCTCGCCATGGCGGCCGACCTGGCGGATGCCTCCAGCGGCTCCCTCA
TGTTCATCGACGAAAACGGCGAAAACCTCAAAATCGAGGCGGCCCTCGGCATGAACATGCAGCTGGCCCAGAGCATGGTG
GTCCAGGTGGGGAGCGGCATTGCCGGCAAGGTGGCGGCCAGCGGCAACCCCCTCCTTGTGAACGACATCGAGAAGGACAA
GCGGATCGGCATCCCCAACCGTCCCCGTTTCAAGACAAAGTCATTCGTCAGCATCCCCATCAAGCTCAGGGAGAGCGTCG
CCGGCGTTCTGAACCTGTCGGACAAGAAGAATCAGGGGATTTTCACCGAGAATGACCTGAATCTGCTCATCACCTTCGCC
GACCATGCCTCCATCATGATCGAGCGGGCCCTGTCCATCGAGCGGGCAGACTTCCTGGAACAGCTGTCAATCACTGACCC
GCTGACTGGCCTCTACAACCGCCGCTTTCTCAAGCGTCGCATGGAAGAGGAACTGGCCCGGAGCATCCGGCAGAACCTCT
CCCTCACCGTGATGCTCATCGACCTGGACAACTTCAAGATCTACAACGACCTCTGCGGCCACCTGGCCGGCGACCGGGCA
CTGAAGAAAATGGCACGGATCCTCTCCGACACCGCCCGGCAGATGGACGTGGTAACCCGCTACGGCGGGGAGGAGTTCTG
CATCATCCTTCCCGGCACCTCCAAGAAGGAATCGCTCTTTGTGGCCGAGCGGATTCGGCGCGAGATCGAAGGGGAGGAGT
TTTCACACGAGGAGAACCTCCCCCAGGGGCGCCTCACTGCCAGCATCGGCGTCTCCTCCTTCCCGGAGGACGGCAACGTC
GAGGCAGTACTCGTCAAGGCCGCCGACGTGGCCCTCTACCGCGCCAAATCGGAGGGACGCAACCGGGTGGTTATCTCCGG
CCCACCGCCGGCCGAGGAGGAACACGGCACCCGCCTCAAGACCGTCACTAATCTGCCATGA

Upstream 100 bases:

>100_bases
GCCAGGGGGTGCCGGTGTCCGATGCCCAGCCGACGCTGCTCATCGAGGAAATAACCGTGGGCGGAGCCGCCTGACCTTTG
GAAGAAACGGGACAACTATC

Downstream 100 bases:

>100_bases
AAAAGGCCGCCCGATGACTCGGACGGCCTTTTTATCTACCCTCAACCTGCGCTATTTCCCCTCACCCGACCTTCGGCCAC
CCTCTCCCCAAGGGAGAGGG

Product: diguanylate cyclase with GAF sensor

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MHHAELTTIQPVELLEVLKSYPFLAPYQLTFCAETEGGMPLYRSLFPVCEAIAQSLLCGKACQTAVEEAVQRAMGENRAV
VFRCQTGLLNFAVPLRGRDIPFTCLIGGGVREKDVDLAPMESLAQTDSVDAVALLEELENLPAVTEEEVAETARKIHELL
PTLLGRNIHTLIFENTMRRLASISGVAGGIDAAKTADEVLGLLSETLGILFDIGRIAMLSPEGSSTFSMKGLWGMEPDLG
TMPAARALSIFPRNRKENVVTLDDECRTLFPEIAANQGLCIRFASNGDFLGIMVLFDAAITRRDKLLVQLVADRASAKLL
RLREEEKHSADNAQATKLMTMFTALSRATSKEELNEQILAMAADLADASSGSLMFIDENGENLKIEAALGMNMQLAQSMV
VQVGSGIAGKVAASGNPLLVNDIEKDKRIGIPNRPRFKTKSFVSIPIKLRESVAGVLNLSDKKNQGIFTENDLNLLITFA
DHASIMIERALSIERADFLEQLSITDPLTGLYNRRFLKRRMEEELARSIRQNLSLTVMLIDLDNFKIYNDLCGHLAGDRA
LKKMARILSDTARQMDVVTRYGGEEFCIILPGTSKKESLFVAERIRREIEGEEFSHEENLPQGRLTASIGVSSFPEDGNV
EAVLVKAADVALYRAKSEGRNRVVISGPPPAEEEHGTRLKTVTNLP

Sequences:

>Translated_686_residues
MHHAELTTIQPVELLEVLKSYPFLAPYQLTFCAETEGGMPLYRSLFPVCEAIAQSLLCGKACQTAVEEAVQRAMGENRAV
VFRCQTGLLNFAVPLRGRDIPFTCLIGGGVREKDVDLAPMESLAQTDSVDAVALLEELENLPAVTEEEVAETARKIHELL
PTLLGRNIHTLIFENTMRRLASISGVAGGIDAAKTADEVLGLLSETLGILFDIGRIAMLSPEGSSTFSMKGLWGMEPDLG
TMPAARALSIFPRNRKENVVTLDDECRTLFPEIAANQGLCIRFASNGDFLGIMVLFDAAITRRDKLLVQLVADRASAKLL
RLREEEKHSADNAQATKLMTMFTALSRATSKEELNEQILAMAADLADASSGSLMFIDENGENLKIEAALGMNMQLAQSMV
VQVGSGIAGKVAASGNPLLVNDIEKDKRIGIPNRPRFKTKSFVSIPIKLRESVAGVLNLSDKKNQGIFTENDLNLLITFA
DHASIMIERALSIERADFLEQLSITDPLTGLYNRRFLKRRMEEELARSIRQNLSLTVMLIDLDNFKIYNDLCGHLAGDRA
LKKMARILSDTARQMDVVTRYGGEEFCIILPGTSKKESLFVAERIRREIEGEEFSHEENLPQGRLTASIGVSSFPEDGNV
EAVLVKAADVALYRAKSEGRNRVVISGPPPAEEEHGTRLKTVTNLP
>Mature_686_residues
MHHAELTTIQPVELLEVLKSYPFLAPYQLTFCAETEGGMPLYRSLFPVCEAIAQSLLCGKACQTAVEEAVQRAMGENRAV
VFRCQTGLLNFAVPLRGRDIPFTCLIGGGVREKDVDLAPMESLAQTDSVDAVALLEELENLPAVTEEEVAETARKIHELL
PTLLGRNIHTLIFENTMRRLASISGVAGGIDAAKTADEVLGLLSETLGILFDIGRIAMLSPEGSSTFSMKGLWGMEPDLG
TMPAARALSIFPRNRKENVVTLDDECRTLFPEIAANQGLCIRFASNGDFLGIMVLFDAAITRRDKLLVQLVADRASAKLL
RLREEEKHSADNAQATKLMTMFTALSRATSKEELNEQILAMAADLADASSGSLMFIDENGENLKIEAALGMNMQLAQSMV
VQVGSGIAGKVAASGNPLLVNDIEKDKRIGIPNRPRFKTKSFVSIPIKLRESVAGVLNLSDKKNQGIFTENDLNLLITFA
DHASIMIERALSIERADFLEQLSITDPLTGLYNRRFLKRRMEEELARSIRQNLSLTVMLIDLDNFKIYNDLCGHLAGDRA
LKKMARILSDTARQMDVVTRYGGEEFCIILPGTSKKESLFVAERIRREIEGEEFSHEENLPQGRLTASIGVSSFPEDGNV
EAVLVKAADVALYRAKSEGRNRVVISGPPPAEEEHGTRLKTVTNLP

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=43.0379746835443, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=36.3095238095238, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI87082007, Length=264, Percent_Identity=34.469696969697, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081881, Length=166, Percent_Identity=40.9638554216867, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1787802, Length=206, Percent_Identity=35.9223300970874, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1787816, Length=177, Percent_Identity=36.1581920903955, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=35.5828220858896, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788381, Length=181, Percent_Identity=32.5966850828729, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788085, Length=168, Percent_Identity=34.5238095238095, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081974, Length=160, Percent_Identity=31.25, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081977, Length=342, Percent_Identity=26.9005847953216, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1787541, Length=170, Percent_Identity=30, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 75290; Mature: 75290

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHAELTTIQPVELLEVLKSYPFLAPYQLTFCAETEGGMPLYRSLFPVCEAIAQSLLCGK
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ACQTAVEEAVQRAMGENRAVVFRCQTGLLNFAVPLRGRDIPFTCLIGGGVREKDVDLAPM
HHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCHH
ESLAQTDSVDAVALLEELENLPAVTEEEVAETARKIHELLPTLLGRNIHTLIFENTMRRL
HHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ASISGVAGGIDAAKTADEVLGLLSETLGILFDIGRIAMLSPEGSSTFSMKGLWGMEPDLG
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCCCCCC
TMPAARALSIFPRNRKENVVTLDDECRTLFPEIAANQGLCIRFASNGDFLGIMVLFDAAI
CCCHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCCEEEHHHHHHHHH
TRRDKLLVQLVADRASAKLLRLREEEKHSADNAQATKLMTMFTALSRATSKEELNEQILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MAADLADASSGSLMFIDENGENLKIEAALGMNMQLAQSMVVQVGSGIAGKVAASGNPLLV
HHHHHCCCCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCEEE
NDIEKDKRIGIPNRPRFKTKSFVSIPIKLRESVAGVLNLSDKKNQGIFTENDLNLLITFA
ECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEEEC
DHASIMIERALSIERADFLEQLSITDPLTGLYNRRFLKRRMEEELARSIRQNLSLTVMLI
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
DLDNFKIYNDLCGHLAGDRALKKMARILSDTARQMDVVTRYGGEEFCIILPGTSKKESLF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
VAERIRREIEGEEFSHEENLPQGRLTASIGVSSFPEDGNVEAVLVKAADVALYRAKSEGR
HHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEEEHHHHEEEECCCCC
NRVVISGPPPAEEEHGTRLKTVTNLP
CEEEECCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MHHAELTTIQPVELLEVLKSYPFLAPYQLTFCAETEGGMPLYRSLFPVCEAIAQSLLCGK
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ACQTAVEEAVQRAMGENRAVVFRCQTGLLNFAVPLRGRDIPFTCLIGGGVREKDVDLAPM
HHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCHH
ESLAQTDSVDAVALLEELENLPAVTEEEVAETARKIHELLPTLLGRNIHTLIFENTMRRL
HHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ASISGVAGGIDAAKTADEVLGLLSETLGILFDIGRIAMLSPEGSSTFSMKGLWGMEPDLG
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCCCCCC
TMPAARALSIFPRNRKENVVTLDDECRTLFPEIAANQGLCIRFASNGDFLGIMVLFDAAI
CCCHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCCEEEHHHHHHHHH
TRRDKLLVQLVADRASAKLLRLREEEKHSADNAQATKLMTMFTALSRATSKEELNEQILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MAADLADASSGSLMFIDENGENLKIEAALGMNMQLAQSMVVQVGSGIAGKVAASGNPLLV
HHHHHCCCCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCEEE
NDIEKDKRIGIPNRPRFKTKSFVSIPIKLRESVAGVLNLSDKKNQGIFTENDLNLLITFA
ECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEEEC
DHASIMIERALSIERADFLEQLSITDPLTGLYNRRFLKRRMEEELARSIRQNLSLTVMLI
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
DLDNFKIYNDLCGHLAGDRALKKMARILSDTARQMDVVTRYGGEEFCIILPGTSKKESLF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
VAERIRREIEGEEFSHEENLPQGRLTASIGVSSFPEDGNVEAVLVKAADVALYRAKSEGR
HHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEEEHHHHEEEECCCCC
NRVVISGPPPAEEEHGTRLKTVTNLP
CEEEECCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]