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The map label for this gene is ahpC [C]

Identifier: 304570572

GI number: 304570572

Start: 3076407

End: 3077078

Strand: Direct

Name: ahpC [C]

Synonym: NA

Alternate gene names: 304570572

Gene position: 3076407-3077078 (Clockwise)

Preceding gene: 78223917

Following gene: 78223924

Centisome position: 76.96

GC content: 62.5

Gene sequence:

>672_bases
ATGAACCGCATAACGGCACTACTCGCTGCAATCCTCGCCACCTCACTCTTTGCGGGCCCAGCCTGCGCCGCCCCCGAAAA
AGCCGACGACATGACCAAGGCCACGGAGCTCATGGTCCAGCACCACAAGGGGATGGTCCGCACCGCTCCCGAGATGGCCA
AGGTGGGGGAGCCGGCTCCGCCATTTACCCTCGATGCGGTGGTGGACAAGGAATTCAAGAAGGTGAGCCTGGGCGACTAC
CGGGGCAAGTGGGTGGTCCTCTTCTTCTACCCCGCCGACTTCACCTTTGTCTGCCCCACGGAGATCACCGGCTTCAACAA
GGCCATGGATCGGTTCACGGAACTCAATGCCCAGCTTCTCGGCGCCTCCGTGGACAGCAAGTACTCTCACCTGGCCTGGA
TCAAGCGGGGGGACCTGGGCGACCTGAAGTACCCTCTCCTGGCCGACAACAAGAAAGAGGCGACGGCCCGCTATGGCATC
CTCGACGAAAAGGAGGGGGTGGCACTGCGGGGGCTCTTCATCATCGACCCCAACGGTGTCCTCCAGTACCAGGTGGTGAA
CAACCTCTCGGTGGGACGGAGCGTGGATGAGACCCTCCGGGTGCTGGAAGCGCTCCAGACCGGCGAGCTCTGCCCCCTGG
GGTGGAAACCGGGGGAGAAGACGATCAAATAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:
NA

Sequences:

>Translated_223_residues
MNRITALLAAILATSLFAGPACAAPEKADDMTKATELMVQHHKGMVRTAPEMAKVGEPAPPFTLDAVVDKEFKKVSLGDY
RGKWVVLFFYPADFTFVCPTEITGFNKAMDRFTELNAQLLGASVDSKYSHLAWIKRGDLGDLKYPLLADNKKEATARYGI
LDEKEGVALRGLFIIDPNGVLQYQVVNNLSVGRSVDETLRVLEALQTGELCPLGWKPGEKTIK
>Mature_223_residues
MNRITALLAAILATSLFAGPACAAPEKADDMTKATELMVQHHKGMVRTAPEMAKVGEPAPPFTLDAVVDKEFKKVSLGDY
RGKWVVLFFYPADFTFVCPTEITGFNKAMDRFTELNAQLLGASVDSKYSHLAWIKRGDLGDLKYPLLADNKKEATARYGI
LDEKEGVALRGLFIIDPNGVLQYQVVNNLSVGRSVDETLRVLEALQTGELCPLGWKPGEKTIK

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=180, Percent_Identity=54.4444444444444, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI32455266, Length=180, Percent_Identity=54.4444444444444, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI32455264, Length=180, Percent_Identity=54.4444444444444, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI32189392, Length=179, Percent_Identity=56.4245810055866, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI5802974, Length=177, Percent_Identity=52.5423728813559, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI5453549, Length=178, Percent_Identity=50.561797752809, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=53.1791907514451, Blast_Score=187, Evalue=7e-48,
Organism=Homo sapiens, GI33188454, Length=85, Percent_Identity=57.6470588235294, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI4758638, Length=186, Percent_Identity=31.1827956989247, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786822, Length=177, Percent_Identity=33.8983050847458, Blast_Score=121, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32565831, Length=179, Percent_Identity=55.3072625698324, Blast_Score=202, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI193204376, Length=179, Percent_Identity=55.3072625698324, Blast_Score=202, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI17554494, Length=172, Percent_Identity=50.5813953488372, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI25153706, Length=188, Percent_Identity=28.7234042553192, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323613, Length=180, Percent_Identity=52.7777777777778, Blast_Score=179, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6320661, Length=180, Percent_Identity=51.1111111111111, Blast_Score=177, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6319407, Length=187, Percent_Identity=32.0855614973262, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17738015, Length=188, Percent_Identity=53.1914893617021, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17157991, Length=179, Percent_Identity=50.2793296089386, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24641739, Length=179, Percent_Identity=50.2793296089386, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24656348, Length=178, Percent_Identity=52.247191011236, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI17864676, Length=178, Percent_Identity=52.247191011236, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21357347, Length=181, Percent_Identity=45.3038674033149, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI17975518, Length=189, Percent_Identity=32.2751322751323, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24652436, Length=189, Percent_Identity=32.2751322751323, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24652434, Length=189, Percent_Identity=32.2751322751323, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24581278, Length=183, Percent_Identity=30.0546448087432, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24506; Mature: 24506

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRITALLAAILATSLFAGPACAAPEKADDMTKATELMVQHHKGMVRTAPEMAKVGEPAP
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHCCCCCC
PFTLDAVVDKEFKKVSLGDYRGKWVVLFFYPADFTFVCPTEITGFNKAMDRFTELNAQLL
CEEHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHH
GASVDSKYSHLAWIKRGDLGDLKYPLLADNKKEATARYGILDEKEGVALRGLFIIDPNGV
CCCCCCCHHHEEEEECCCCCCCCCCEECCCCHHHHHHCCCCCCCCCEEEEEEEEECCCCE
LQYQVVNNLSVGRSVDETLRVLEALQTGELCPLGWKPGEKTIK
EEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRITALLAAILATSLFAGPACAAPEKADDMTKATELMVQHHKGMVRTAPEMAKVGEPAP
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHCCCCCC
PFTLDAVVDKEFKKVSLGDYRGKWVVLFFYPADFTFVCPTEITGFNKAMDRFTELNAQLL
CEEHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHH
GASVDSKYSHLAWIKRGDLGDLKYPLLADNKKEATARYGILDEKEGVALRGLFIIDPNGV
CCCCCCCHHHEEEEECCCCCCCCCCEECCCCHHHHHHCCCCCCCCCEEEEEEEEECCCCE
LQYQVVNNLSVGRSVDETLRVLEALQTGELCPLGWKPGEKTIK
EEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]