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The map label for this gene is yycF [H]

Identifier: 78223889

GI number: 78223889

Start: 3040555

End: 3041235

Strand: Direct

Name: yycF [H]

Synonym: Gmet_2693

Alternate gene names: 78223889

Gene position: 3040555-3041235 (Clockwise)

Preceding gene: 78223884

Following gene: 78223890

Centisome position: 76.06

GC content: 60.5

Gene sequence:

>681_bases
ATGCAAACCGTCCTGATCATCGAAGACGAAAAAGACCTGGCGGAACTCGTTTCCTTCAACCTGGAGAAGGAAGGATACCG
GACCATCGCGGCCCCCGATGGCATCAGCGGCCTCGACGAGGCACAGAGGCAGGTCCCGGACCTTATCTTACTCGACCTGA
TGCTCCCGGGCATGATGGGAACCGAGGTCTGCAAGATACTGAAAAAGTCGGAGAAAACCGCGAAAATCCCAGTCATCATG
CTGACGGCCCGGGGAGAAGAGATCGACCGGGTGGTGGGGTTCGAGGTGGGCGCCGACGATTACGTGGTGAAGCCCTTCTC
CACCCGGGAACTGCTCCTGAGGATCAAAGCGGTGCTGCGCCGTTCGCTGCCGGACGAACCCTCGGGAAAAACCATGAGGA
TCGGGCCGATCGCCATCGACCCGGACCGCCACACGGTGGCCGTGGCAGGGGAAGAGATAGTCCTTACCACCACTGAATTC
AAGCTGCTCCTCAATCTCGCCGAACGCCTGGGGCGGGTCCAGAGCCGCGACCTTCTCCTGAAAAACGTCTGGGGATACAA
CTACGTGGGGGACACCCGCACGGTTGACACGCACATCACTCGTCTGCGCACGAAGCTGGGCCCGGCCGGCGACCTGATCA
AGACAGTTCGCGGTTTCGGCTACAAGATGGAGGAGCCGTGA

Upstream 100 bases:

>100_bases
GAAAGTCCGCTTACAGGCCGTTTTTACGGCTTTTTTTCACACCTGTAACACGAATGCAATATTCAGAACATACCATCTCC
GGCAAGGAGATACTAAACGA

Downstream 100 bases:

>100_bases
GATTCACCATCCAGTGGAAGCTCATGGCTTCCTACCTCCTTCTCGTGCTCTTCATCGGCGGGGTCTTCTTCGCCTACCTG
AACCACACCCTGAACCAGCA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MQTVLIIEDEKDLAELVSFNLEKEGYRTIAAPDGISGLDEAQRQVPDLILLDLMLPGMMGTEVCKILKKSEKTAKIPVIM
LTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRIKAVLRRSLPDEPSGKTMRIGPIAIDPDRHTVAVAGEEIVLTTTEF
KLLLNLAERLGRVQSRDLLLKNVWGYNYVGDTRTVDTHITRLRTKLGPAGDLIKTVRGFGYKMEEP

Sequences:

>Translated_226_residues
MQTVLIIEDEKDLAELVSFNLEKEGYRTIAAPDGISGLDEAQRQVPDLILLDLMLPGMMGTEVCKILKKSEKTAKIPVIM
LTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRIKAVLRRSLPDEPSGKTMRIGPIAIDPDRHTVAVAGEEIVLTTTEF
KLLLNLAERLGRVQSRDLLLKNVWGYNYVGDTRTVDTHITRLRTKLGPAGDLIKTVRGFGYKMEEP
>Mature_226_residues
MQTVLIIEDEKDLAELVSFNLEKEGYRTIAAPDGISGLDEAQRQVPDLILLDLMLPGMMGTEVCKILKKSEKTAKIPVIM
LTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRIKAVLRRSLPDEPSGKTMRIGPIAIDPDRHTVAVAGEEIVLTTTEF
KLLLNLAERLGRVQSRDLLLKNVWGYNYVGDTRTVDTHITRLRTKLGPAGDLIKTVRGFGYKMEEP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=46.3963963963964, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=39.5555555555556, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=38.8392857142857, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=40.990990990991, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=40.5172413793103, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.8888888888889, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=37.280701754386, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.4260089686099, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=34.375, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=34.1880341880342, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786911, Length=206, Percent_Identity=35.9223300970874, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=31.9148936170213, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=35.5263157894737, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=28.6995515695067, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=32.4786324786325, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25217; Mature: 25217

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVLIIEDEKDLAELVSFNLEKEGYRTIAAPDGISGLDEAQRQVPDLILLDLMLPGMMG
CCEEEEEECCHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHCHHHHHHHHHCCCCHH
TEVCKILKKSEKTAKIPVIMLTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRIKAVLR
HHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHCEEECCCCEEECCCCHHHHHHHHHHHHH
RSLPDEPSGKTMRIGPIAIDPDRHTVAVAGEEIVLTTTEFKLLLNLAERLGRVQSRDLLL
HCCCCCCCCCEEEECCEEECCCCCEEEEECCEEEEEHHHHHHHHHHHHHHCCHHHHHHHH
KNVWGYNYVGDTRTVDTHITRLRTKLGPAGDLIKTVRGFGYKMEEP
HHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEECCCC
>Mature Secondary Structure
MQTVLIIEDEKDLAELVSFNLEKEGYRTIAAPDGISGLDEAQRQVPDLILLDLMLPGMMG
CCEEEEEECCHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHCHHHHHHHHHCCCCHH
TEVCKILKKSEKTAKIPVIMLTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRIKAVLR
HHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHCEEECCCCEEECCCCHHHHHHHHHHHHH
RSLPDEPSGKTMRIGPIAIDPDRHTVAVAGEEIVLTTTEFKLLLNLAERLGRVQSRDLLL
HCCCCCCCCCEEEECCEEECCCCCEEEEECCEEEEEHHHHHHHHHHHHHHCCHHHHHHHH
KNVWGYNYVGDTRTVDTHITRLRTKLGPAGDLIKTVRGFGYKMEEP
HHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]