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The map label for this gene is dhaR [H]

Identifier: 78223841

GI number: 78223841

Start: 2995013

End: 2995597

Strand: Direct

Name: dhaR [H]

Synonym: Gmet_2645

Alternate gene names: 78223841

Gene position: 2995013-2995597 (Clockwise)

Preceding gene: 78223835

Following gene: 78223842

Centisome position: 74.92

GC content: 54.02

Gene sequence:

>585_bases
ATGAAATCCAAAGGCGAAGAAACAAGAAGCAGAATACTTGATACGGCGACGGATCTCATCCACCGCAAGGGCTTCGGGGC
CACGAGCATCAATGACTTGCTTGAGGCAACCAATATCAAGAAAGGCTGTCTTTACTTCCATTTTCCTGGAAAGGATGCCT
TGGGGCTGGCCGTGCTGGAGAAGATGCGGGATGATTTCCTCGATGTTTTGGAGACCTCCCTGGCCGGCACCACACCGGGG
GAGTGTCTTGATAATTTTTTCGCCACGGTCGCAGATGTACACAAGGGGAGGGGATTCGTCGGGGGGTGCATTTTTGGAAA
TACCGCCCTGGAAATGGGGGACACGGACAATCGTTTAGTGGCTATAATCAGGCAGGTCTTTAAAACATGGCTGGGCAAAT
TGAAGACGGTTATCGCCGCCGCCCAGAACAGTGGTGAGGTACGCAACGACATCCCAGCAGACATCCTGGCCTGCCAGATG
CTGGCCGCCATCGAGGGGGGTATAATGCTGTCCCGTCTGGAAAAGGATGAGAAGCCCCTGTGCGATGCCCTCGGCGCCTT
ACGGACAATGATGCGAGTGAAGTAG

Upstream 100 bases:

>100_bases
GCTGTGACCCTTTTATGCTTCCAGTGCATATATTCCACCTTGACAACATTTCTTTATCCGTTAAATTAGACCAAACGGTT
GGTTTTTGAGGAAATGCATA

Downstream 100 bases:

>100_bases
CAAAATTTTTTTCAATAAAAACAAACCAAATGGTCGGTTTGTTGGCCCTCAGGGGCAAATACAAACAGCTGAAAAGGAGA
GGCAGATGGCGCGTTTGACA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKSKGEETRSRILDTATDLIHRKGFGATSINDLLEATNIKKGCLYFHFPGKDALGLAVLEKMRDDFLDVLETSLAGTTPG
ECLDNFFATVADVHKGRGFVGGCIFGNTALEMGDTDNRLVAIIRQVFKTWLGKLKTVIAAAQNSGEVRNDIPADILACQM
LAAIEGGIMLSRLEKDEKPLCDALGALRTMMRVK

Sequences:

>Translated_194_residues
MKSKGEETRSRILDTATDLIHRKGFGATSINDLLEATNIKKGCLYFHFPGKDALGLAVLEKMRDDFLDVLETSLAGTTPG
ECLDNFFATVADVHKGRGFVGGCIFGNTALEMGDTDNRLVAIIRQVFKTWLGKLKTVIAAAQNSGEVRNDIPADILACQM
LAAIEGGIMLSRLEKDEKPLCDALGALRTMMRVK
>Mature_194_residues
MKSKGEETRSRILDTATDLIHRKGFGATSINDLLEATNIKKGCLYFHFPGKDALGLAVLEKMRDDFLDVLETSLAGTTPG
ECLDNFFATVADVHKGRGFVGGCIFGNTALEMGDTDNRLVAIIRQVFKTWLGKLKTVIAAAQNSGEVRNDIPADILACQM
LAAIEGGIMLSRLEKDEKPLCDALGALRTMMRVK

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21093; Mature: 21093

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKGEETRSRILDTATDLIHRKGFGATSINDLLEATNIKKGCLYFHFPGKDALGLAVLE
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
KMRDDFLDVLETSLAGTTPGECLDNFFATVADVHKGRGFVGGCIFGNTALEMGDTDNRLV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEHEECCCHHCCCCCCHHHH
AIIRQVFKTWLGKLKTVIAAAQNSGEVRNDIPADILACQMLAAIEGGIMLSRLEKDEKPL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHH
CDALGALRTMMRVK
HHHHHHHHHHHHCC
>Mature Secondary Structure
MKSKGEETRSRILDTATDLIHRKGFGATSINDLLEATNIKKGCLYFHFPGKDALGLAVLE
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
KMRDDFLDVLETSLAGTTPGECLDNFFATVADVHKGRGFVGGCIFGNTALEMGDTDNRLV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEHEECCCHHCCCCCCHHHH
AIIRQVFKTWLGKLKTVIAAAQNSGEVRNDIPADILACQMLAAIEGGIMLSRLEKDEKPL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHH
CDALGALRTMMRVK
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]