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The map label for this gene is 78223813

Identifier: 78223813

GI number: 78223813

Start: 2961941

End: 2962471

Strand: Direct

Name: 78223813

Synonym: Gmet_2616

Alternate gene names: NA

Gene position: 2961941-2962471 (Clockwise)

Preceding gene: 78223811

Following gene: 78223814

Centisome position: 74.1

GC content: 62.34

Gene sequence:

>531_bases
ATGAACACCCCCCATTCCGTCGAAACAAAGGAACTGCCCCCACCCCGACGGCATCACCGGAAGATCCCCGTCCTCGCAAT
CCTGATGATCATGGCACTCCCCGCAGCCGGCTTCGGCGACAGACCGGCATACGCCGACAGCTGCGCCGACGTCGTCCACC
AGGTGAACCGGCAGCTCAGACCCACGATCGACGAAGGGGAACTGGCCGCCATGCTCCAGAGCCTCAACGGAAGCAACAAC
AGGAACCTTCCCCCGAAATTCGTGACCAAGGCCCAGGCGAAAAAGATGGGATGGAGACCGGGAAGAGACCTCTGGGCCTC
CACTAGGCTCAAAGGGAAGAGCATTGGGGGCGACCGGTTTGCCAACAGGGAGGGGCGGCTGCCGGCCGGCGGCAAGAAAT
GGCATGAGGCTGACCTGGACTACCAGGGGGGGCACCGGGGGGCGAAGCGCCTGATTTACTCAAATGACGGCCTGAGGATG
GTGACGGTTGACCATTATCGCACCTTCACGGAGGTCCCCCCATGCCAGTAA

Upstream 100 bases:

>100_bases
CTCAAGGATGAGCGTATTGCGCCAGGGATGGCGTACTCAACCTTCCCACCGCCGCTCATTCGGCTGAGCGCAATCCCCTC
TTCAGGAGAGCATACAGACC

Downstream 100 bases:

>100_bases
AGCGAGTGAAGCACTGCACCATTTCTGGCCGGGCTGTCCACTCCCTTGACGAGCTGTACGACGAGATCGCCCGCCAGCTT
CCCCTTCCCGATTACTTCGG

Product: guanine-specific ribonuclease N1 and T1

Products: NA

Alternate protein names: Binase; RNase Bi [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNTPHSVETKELPPPRRHHRKIPVLAILMIMALPAAGFGDRPAYADSCADVVHQVNRQLRPTIDEGELAAMLQSLNGSNN
RNLPPKFVTKAQAKKMGWRPGRDLWASTRLKGKSIGGDRFANREGRLPAGGKKWHEADLDYQGGHRGAKRLIYSNDGLRM
VTVDHYRTFTEVPPCQ

Sequences:

>Translated_176_residues
MNTPHSVETKELPPPRRHHRKIPVLAILMIMALPAAGFGDRPAYADSCADVVHQVNRQLRPTIDEGELAAMLQSLNGSNN
RNLPPKFVTKAQAKKMGWRPGRDLWASTRLKGKSIGGDRFANREGRLPAGGKKWHEADLDYQGGHRGAKRLIYSNDGLRM
VTVDHYRTFTEVPPCQ
>Mature_176_residues
MNTPHSVETKELPPPRRHHRKIPVLAILMIMALPAAGFGDRPAYADSCADVVHQVNRQLRPTIDEGELAAMLQSLNGSNN
RNLPPKFVTKAQAKKMGWRPGRDLWASTRLKGKSIGGDRFANREGRLPAGGKKWHEADLDYQGGHRGAKRLIYSNDGLRM
VTVDHYRTFTEVPPCQ

Specific function: This is a purine-specific ribonuclease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease N1/T1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001887
- InterPro:   IPR000026
- InterPro:   IPR016191 [H]

Pfam domain/function: PF00545 Ribonuclease [H]

EC number: NA

Molecular weight: Translated: 19670; Mature: 19670

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPHSVETKELPPPRRHHRKIPVLAILMIMALPAAGFGDRPAYADSCADVVHQVNRQLR
CCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
PTIDEGELAAMLQSLNGSNNRNLPPKFVTKAQAKKMGWRPGRDLWASTRLKGKSIGGDRF
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
ANREGRLPAGGKKWHEADLDYQGGHRGAKRLIYSNDGLRMVTVDHYRTFTEVPPCQ
CCCCCCCCCCCCCCCCCCCCCCCCCHHHCEEEECCCCEEEEEECCHHHHCCCCCCC
>Mature Secondary Structure
MNTPHSVETKELPPPRRHHRKIPVLAILMIMALPAAGFGDRPAYADSCADVVHQVNRQLR
CCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
PTIDEGELAAMLQSLNGSNNRNLPPKFVTKAQAKKMGWRPGRDLWASTRLKGKSIGGDRF
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
ANREGRLPAGGKKWHEADLDYQGGHRGAKRLIYSNDGLRMVTVDHYRTFTEVPPCQ
CCCCCCCCCCCCCCCCCCCCCCCCCHHHCEEEECCCCEEEEEECCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1594455; 2632211; 761620; 9153077; 9708913; 11976484 [H]