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The map label for this gene is macB [H]

Identifier: 78223608

GI number: 78223608

Start: 2719888

End: 2721051

Strand: Reverse

Name: macB [H]

Synonym: Gmet_2405

Alternate gene names: 78223608

Gene position: 2721051-2719888 (Counterclockwise)

Preceding gene: 78223609

Following gene: 78223606

Centisome position: 68.07

GC content: 63.06

Gene sequence:

>1164_bases
ATGGGCATCCCTTACTCCTACAGCTTCCGCAACCTCTGGACCCGGCGTCTGACCACGGTCCTTACCGCCTCAGGCATGGC
GCTGGTCGTCTTTGTCTTTGCGGCAACCCTCATGCTGGCCGAGGGGCTTCGGAAGACCCTGGTGGATACCGGTTCCTACG
ACAACGTGGTGGTGATCCGCAAGTCGGCCCAGACCGAGGTGCAGAGCGGCATCGACCGTTCCCAGGCCGCGGTGGTGGAA
ACTCAGCCCGAGATCGCGGTGGAGGGGGGAGAGCGTCTTGTCGCGAAGGAAATCGTGGTCCTCATCAGCCTTCCTAAGCG
GGGGAGTGGTAAGCCCTCCAACGTCATTATCCGGGGGGTAAGTGCCACATCGCTCCTCATGCGCCCCCAGGTGAAAGTCA
TTGAGGGACGGATGCCGCGCCCCGGCTCGGCCGAGATCATGGCAGGAGCCAGCATTGCCAAGCGCTTCAAGGGGGGAGGT
ATCGGCGAGACCCTGCGCTTCGGCATGCGGGACTGGACCGTGGTGGGAATCTTCGAGGCCGGCAATACCGGCTTCTCATC
GGAGATATGGGGCGACGTGGACCAGCTCATGCAGGCCTTCCGCCGGCCCGTCTACTCCTCCATCATCTTCAAGTTGCGGG
ACCCGTCGGAGTTCGTCAGGGTGAAGGAGCGGATCGAGGGCGACCCGCGCCTGACCCTGGAAGCGAAGCGGGAGATCACC
TTCTACGCCGATCAGTCCCAGGCCATGGCCAAGTTTCTCCGGATTCTCGGGATAACCCTCACCATCATCTTCTCCCTCGG
GGCGGTCATCGGCGCCATGATCACCATGTACGCCGCCGTGGCCAACCGGGTCACCGAGATAGGCACCCTGCGGGCCCTGG
GCTTCCAGCGGGGGAGCATTCTGGCCGCCTTCATCCTGGAGTCGCTCTTCCTGGGGCTCCTGGGCGGGGTGGTGGGGCTT
TTCTTCGCTTCGTTCATGCAACTGGTCACCATCTCCACCATGAACTGGCAGACCTTTTCGGAGCTGGCTTTCACCTTCTC
CCTCACCCCCGGCATCATCGGCAAGTCGCTTATCTTTTCCCTCGTCATGGGGTTTGTGGGGGGATTGCTGCCGGCCTTCC
GGGCGGCGCGGATGAATATCGTGGATGCGCTGCGGGCGACGTAG

Upstream 100 bases:

>100_bases
CCTGGCCGCCGCCCTCGTGGTGGGGGTCGTGGCGGGAATCTTCCCCACCTGGCGAGGGGCGACCATTGGAATAGCGGATG
GCCTGCGGAGGATAGGGTAG

Downstream 100 bases:

>100_bases
CGTTTTTCTGCTGTTCGGAGAGTGGTTTTGGGGGGGTCAGAGCCCCAGGGCGTTCTGGGTCTCTGCCAGGTAGGTACGCA
CGGCGCCGGAACTGACGAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MGIPYSYSFRNLWTRRLTTVLTASGMALVVFVFAATLMLAEGLRKTLVDTGSYDNVVVIRKSAQTEVQSGIDRSQAAVVE
TQPEIAVEGGERLVAKEIVVLISLPKRGSGKPSNVIIRGVSATSLLMRPQVKVIEGRMPRPGSAEIMAGASIAKRFKGGG
IGETLRFGMRDWTVVGIFEAGNTGFSSEIWGDVDQLMQAFRRPVYSSIIFKLRDPSEFVRVKERIEGDPRLTLEAKREIT
FYADQSQAMAKFLRILGITLTIIFSLGAVIGAMITMYAAVANRVTEIGTLRALGFQRGSILAAFILESLFLGLLGGVVGL
FFASFMQLVTISTMNWQTFSELAFTFSLTPGIIGKSLIFSLVMGFVGGLLPAFRAARMNIVDALRAT

Sequences:

>Translated_387_residues
MGIPYSYSFRNLWTRRLTTVLTASGMALVVFVFAATLMLAEGLRKTLVDTGSYDNVVVIRKSAQTEVQSGIDRSQAAVVE
TQPEIAVEGGERLVAKEIVVLISLPKRGSGKPSNVIIRGVSATSLLMRPQVKVIEGRMPRPGSAEIMAGASIAKRFKGGG
IGETLRFGMRDWTVVGIFEAGNTGFSSEIWGDVDQLMQAFRRPVYSSIIFKLRDPSEFVRVKERIEGDPRLTLEAKREIT
FYADQSQAMAKFLRILGITLTIIFSLGAVIGAMITMYAAVANRVTEIGTLRALGFQRGSILAAFILESLFLGLLGGVVGL
FFASFMQLVTISTMNWQTFSELAFTFSLTPGIIGKSLIFSLVMGFVGGLLPAFRAARMNIVDALRAT
>Mature_386_residues
GIPYSYSFRNLWTRRLTTVLTASGMALVVFVFAATLMLAEGLRKTLVDTGSYDNVVVIRKSAQTEVQSGIDRSQAAVVET
QPEIAVEGGERLVAKEIVVLISLPKRGSGKPSNVIIRGVSATSLLMRPQVKVIEGRMPRPGSAEIMAGASIAKRFKGGGI
GETLRFGMRDWTVVGIFEAGNTGFSSEIWGDVDQLMQAFRRPVYSSIIFKLRDPSEFVRVKERIEGDPRLTLEAKREITF
YADQSQAMAKFLRILGITLTIIFSLGAVIGAMITMYAAVANRVTEIGTLRALGFQRGSILAAFILESLFLGLLGGVVGLF
FASFMQLVTISTMNWQTFSELAFTFSLTPGIIGKSLIFSLVMGFVGGLLPAFRAARMNIVDALRAT

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42106; Mature: 41975

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIPYSYSFRNLWTRRLTTVLTASGMALVVFVFAATLMLAEGLRKTLVDTGSYDNVVVIR
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
KSAQTEVQSGIDRSQAAVVETQPEIAVEGGERLVAKEIVVLISLPKRGSGKPSNVIIRGV
CCHHHHHHHCCCHHHHEEEECCCCEEECCCCHHHHHHHHHEEECCCCCCCCCCCEEEECC
SATSLLMRPQVKVIEGRMPRPGSAEIMAGASIAKRFKGGGIGETLRFGMRDWTVVGIFEA
CHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEC
GNTGFSSEIWGDVDQLMQAFRRPVYSSIIFKLRDPSEFVRVKERIEGDPRLTLEAKREIT
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCEEE
FYADQSQAMAKFLRILGITLTIIFSLGAVIGAMITMYAAVANRVTEIGTLRALGFQRGSI
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAAFILESLFLGLLGGVVGLFFASFMQLVTISTMNWQTFSELAFTFSLTPGIIGKSLIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCHHHHHHHHHH
LVMGFVGGLLPAFRAARMNIVDALRAT
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GIPYSYSFRNLWTRRLTTVLTASGMALVVFVFAATLMLAEGLRKTLVDTGSYDNVVVIR
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
KSAQTEVQSGIDRSQAAVVETQPEIAVEGGERLVAKEIVVLISLPKRGSGKPSNVIIRGV
CCHHHHHHHCCCHHHHEEEECCCCEEECCCCHHHHHHHHHEEECCCCCCCCCCCEEEECC
SATSLLMRPQVKVIEGRMPRPGSAEIMAGASIAKRFKGGGIGETLRFGMRDWTVVGIFEA
CHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEC
GNTGFSSEIWGDVDQLMQAFRRPVYSSIIFKLRDPSEFVRVKERIEGDPRLTLEAKREIT
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCEEE
FYADQSQAMAKFLRILGITLTIIFSLGAVIGAMITMYAAVANRVTEIGTLRALGFQRGSI
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAAFILESLFLGLLGGVVGLFFASFMQLVTISTMNWQTFSELAFTFSLTPGIIGKSLIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCHHHHHHHHHH
LVMGFVGGLLPAFRAARMNIVDALRAT
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA