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The map label for this gene is fabZ

Identifier: 78223557

GI number: 78223557

Start: 2661619

End: 2662071

Strand: Reverse

Name: fabZ

Synonym: Gmet_2354

Alternate gene names: 78223557

Gene position: 2662071-2661619 (Counterclockwise)

Preceding gene: 78223558

Following gene: 78223556

Centisome position: 66.59

GC content: 55.41

Gene sequence:

>453_bases
ATGGAAACTGTCTTTGATATCAATGAAATCATGAAAATCCTTCCCCACCGTTACCCCTTTCTCCTGGTGGACCGGATCGT
GGAGCACGTGCCGGGAGAAAGGATCGTGGGGATCAAGAACGTTACCATCAACGAGCCTTTCTTCCAGGGACATTTCCCCG
GTCATCCCATCATGCCGGGGGTGCTGATTGTCGAGGCCATGGCCCAGGTGGGTGGTATCCTTGCATACATGGCATCGGAC
GACGAAGTCCGGAATAAAGTCTGCTATTTTGCTTCCATTGACAACGTGAAATTCCGCAAGCCGGTGCTGCCGGGAGACCA
ACTCCGGATCGAGGTTGCGGCCACCGGGTGCAAGCGCGGCATCTGGTGTTTCAGCGCCAAGGCCATTGTCAAGGGGAAGG
TGACGACCCAGGCGGAACTCAAGGCCACCTTTGCCGACAAGGACAGGTTGTAA

Upstream 100 bases:

>100_bases
GAGCGTCTGCGGTGGTGCCGAAACTCCCTGAACTGAGGAAGACGATCGCCGAACTGGAGAAGCGGGTCAGGGAACTGGAA
GAGAAACAAGGAGCCTGATA

Downstream 100 bases:

>100_bases
CAATGATTCATCCCACGGCAATCGTACACCCCGAGGCGCAGGTGGCCGAAGGGGTCGAGATCGGCCCCTATGCCATCATC
GGCGAGCATGTCAGGATCGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
METVFDINEIMKILPHRYPFLLVDRIVEHVPGERIVGIKNVTINEPFFQGHFPGHPIMPGVLIVEAMAQVGGILAYMASD
DEVRNKVCYFASIDNVKFRKPVLPGDQLRIEVAATGCKRGIWCFSAKAIVKGKVTTQAELKATFADKDRL

Sequences:

>Translated_150_residues
METVFDINEIMKILPHRYPFLLVDRIVEHVPGERIVGIKNVTINEPFFQGHFPGHPIMPGVLIVEAMAQVGGILAYMASD
DEVRNKVCYFASIDNVKFRKPVLPGDQLRIEVAATGCKRGIWCFSAKAIVKGKVTTQAELKATFADKDRL
>Mature_150_residues
METVFDINEIMKILPHRYPFLLVDRIVEHVPGERIVGIKNVTINEPFFQGHFPGHPIMPGVLIVEAMAQVGGILAYMASD
DEVRNKVCYFASIDNVKFRKPVLPGDQLRIEVAATGCKRGIWCFSAKAIVKGKVTTQAELKATFADKDRL

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=137, Percent_Identity=49.6350364963504, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_GEOMG (Q39T45)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_385304.1
- ProteinModelPortal:   Q39T45
- SMR:   Q39T45
- STRING:   Q39T45
- GeneID:   3738814
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_2354
- NMPDR:   fig|269799.3.peg.2598
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q39T45
- ProtClustDB:   PRK00006
- BioCyc:   GMET269799:GMET_2354-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16769; Mature: 16769

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: ACT_SITE 51-51

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVFDINEIMKILPHRYPFLLVDRIVEHVPGERIVGIKNVTINEPFFQGHFPGHPIMPG
CCCEECHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECEEECCCCCCCCCCCCCCCHH
VLIVEAMAQVGGILAYMASDDEVRNKVCYFASIDNVKFRKPVLPGDQLRIEVAATGCKRG
HHHHHHHHHHHHEEEEECCCHHHHCEEEEEEECCCCEECCCCCCCCCEEEEEEECCCCCC
IWCFSAKAIVKGKVTTQAELKATFADKDRL
EEEEECCEEEECCCCCHHHEEEECCCCCCC
>Mature Secondary Structure
METVFDINEIMKILPHRYPFLLVDRIVEHVPGERIVGIKNVTINEPFFQGHFPGHPIMPG
CCCEECHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECEEECCCCCCCCCCCCCCCHH
VLIVEAMAQVGGILAYMASDDEVRNKVCYFASIDNVKFRKPVLPGDQLRIEVAATGCKRG
HHHHHHHHHHHHEEEEECCCHHHHCEEEEEEECCCCEECCCCCCCCCEEEEEEECCCCCC
IWCFSAKAIVKGKVTTQAELKATFADKDRL
EEEEECCEEEECCCCCHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA