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The map label for this gene is bcd [H]

Identifier: 78223474

GI number: 78223474

Start: 2572522

End: 2574369

Strand: Reverse

Name: bcd [H]

Synonym: Gmet_2270

Alternate gene names: 78223474

Gene position: 2574369-2572522 (Counterclockwise)

Preceding gene: 78223478

Following gene: 78223473

Centisome position: 64.4

GC content: 54.98

Gene sequence:

>1848_bases
GTGGCGAACTTACTGGTTGATAAGCGTGATCAGATATTTGTGCTGAAAGAAATGCTGGAGATTGACCGTCTATGTAGTTT
TCCGAGATATGCCAGTCATGCGGGATACGAGATGGTCCTGAACGAGGCACATACCTTCGCCAACACCGAGTTATCCCCTA
CCGCCGTTGACGGTGACCAGCAGGGATGCCTCTATGACCCGAAGACCAAGGCTGTTACGTTCCCTCAATCGTTTCACAAG
CCATATCAGAAATTTTGTGAAGGTGGCTGGCTGACGATGTGCGACAGCCCCGACGTGGGGGGGGATGGTTTCCCTTCGGC
CGTGGGAACAGCCGTGTCCGAAGTTTTCTACGCCTGCGGTTTTTATATTTACGGGGCAGCCGAGCTGACGCATGCGGCTG
CCAAGGTGATCGAGGCCTATGGGAGCGAAGAGCAGAAAAAGAGCTACATGACCAAGCTCTTTGCCGGGGAGTGGATGGGG
ACCATGTGTCTCACGGAACCTGATGCGGGGAGTGAGGTCGGTGCGGTGCAGACCGTTGCGACCCGCAACGGGGACGGCAG
TTACGCGATTACCGGTACCAAGATATTCATCACTGCCGGCGAGCATGACCTGGCCGGTAACATCATCCACATGGTGCTTG
CCCGGGTGGCAGGCGATCCCCCCGGTACCAAGGGGTTGTCCCTGTTCATCGTTCCCAAGTTCCTCCCCGACGGGGTGGGG
AACGCCGGCGAGCGCAACGATGTTTATTGTACCGGCATTGAGCACAAAATGGGGCTGCACGGACTTGTTACCTGTACCAT
GGCATTTGGCGACAGCGGAAAATGTACCGGATACTTGCTGGGGGAGCAGGGCAAGGGGATGGCGGAGATGTTCCACATGA
TGAATGAGCAGCGCCTTCTGGTCGGTGTTGAGGGGCTCTCATTTTCCACGAGCGCATTCATGAATGCCGTGGATTACACG
AAAAGCCGGGTGCAGGGCCTATCGGTATATCCAGGTGCAGATAAGCAGAAATCGGTGGCGATCATCAATCACCCCGATGT
GAAGCGGATGCTCCTGACCATGAAGGCCTATGTGGAAGGGTGCCGCAGTCTCGCCTATTTCACCAGCAGCTGCATGGATA
ACGCGGGGGTCGCAGATGGTGCGGATCGTGCCAGGTGGCAGGGGTTGGTCGAACTGCTGACCCCGATTGTCAAGGCCTAT
ATCACCGACAATGCCTGGACCGTGACCGCTCTGGCCATGCAGTGCGCCGGGGGGTATGGGTATTGTTCCGATTATCCCTT
TGAACGGTTGGCGCGTGACTGTAAGGTAACCACCATTTTCGAGGGGACCAACGGCATTCAGGCCATGGATCTGATGTTCA
GGAAAATCCTTGGCAACAACAGGGTTAATTTTAACAACCTGCTGGAGATGATCGACCAGACCATAGAAAAGGGGGCTGCA
GACGCTGAGATCAGCGTGTATGCGGCAATTGTAAAGCGTGCCAGGGAGGGTCTTGCACGGATAGTCGAAGAAATGGCTGC
ATCTTCAGCTGCCGGCAATTCCCTTGATCTATACGCAAAGACCAGCCCGTTCCTTGAGGCGATGGGGGATGTCCTCCTCG
GTTGGCTGCATCTGTGGCAGCTGACGGTCGCGAATCCGAAATTGCAGGGTTTCATTGAAAACAAGAGCGAAGACGAAATT
GCCAAGATCCTGAACAAGAACAAGAATGCGGCATTTTACGACGGCAAGGTGCTGGGAGCCCGGTTTTTCATCGGAACGCT
GCTCATGAATACTTTTGGAAAATTCGAGCAGATCAGATCGGGTGCGGCTCCGGTCATCAGCATCGGCGAAAAGTCATTTA
CGGGTTAA

Upstream 100 bases:

>100_bases
GTGCAGCCGGTTTCTTGCTCAGGAGAACAAATCTTCTTTCTGAGTGTCCGGGACTCTATGGAGAATCATAATCGTCAAAT
CATCGCACAGGAGAGAAACG

Downstream 100 bases:

>100_bases
GGGAATGCAGGAGCGGTTTTGAACAGCGACAACAAACTGCGCGGGGAGGAATCCATGGGTATTGGGAAAGTGGCGGTTAT
CGGATCGGGAATCATGGGGC

Product: Acyl-CoA dehydrogenase-like

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MANLLVDKRDQIFVLKEMLEIDRLCSFPRYASHAGYEMVLNEAHTFANTELSPTAVDGDQQGCLYDPKTKAVTFPQSFHK
PYQKFCEGGWLTMCDSPDVGGDGFPSAVGTAVSEVFYACGFYIYGAAELTHAAAKVIEAYGSEEQKKSYMTKLFAGEWMG
TMCLTEPDAGSEVGAVQTVATRNGDGSYAITGTKIFITAGEHDLAGNIIHMVLARVAGDPPGTKGLSLFIVPKFLPDGVG
NAGERNDVYCTGIEHKMGLHGLVTCTMAFGDSGKCTGYLLGEQGKGMAEMFHMMNEQRLLVGVEGLSFSTSAFMNAVDYT
KSRVQGLSVYPGADKQKSVAIINHPDVKRMLLTMKAYVEGCRSLAYFTSSCMDNAGVADGADRARWQGLVELLTPIVKAY
ITDNAWTVTALAMQCAGGYGYCSDYPFERLARDCKVTTIFEGTNGIQAMDLMFRKILGNNRVNFNNLLEMIDQTIEKGAA
DAEISVYAAIVKRAREGLARIVEEMAASSAAGNSLDLYAKTSPFLEAMGDVLLGWLHLWQLTVANPKLQGFIENKSEDEI
AKILNKNKNAAFYDGKVLGARFFIGTLLMNTFGKFEQIRSGAAPVISIGEKSFTG

Sequences:

>Translated_615_residues
MANLLVDKRDQIFVLKEMLEIDRLCSFPRYASHAGYEMVLNEAHTFANTELSPTAVDGDQQGCLYDPKTKAVTFPQSFHK
PYQKFCEGGWLTMCDSPDVGGDGFPSAVGTAVSEVFYACGFYIYGAAELTHAAAKVIEAYGSEEQKKSYMTKLFAGEWMG
TMCLTEPDAGSEVGAVQTVATRNGDGSYAITGTKIFITAGEHDLAGNIIHMVLARVAGDPPGTKGLSLFIVPKFLPDGVG
NAGERNDVYCTGIEHKMGLHGLVTCTMAFGDSGKCTGYLLGEQGKGMAEMFHMMNEQRLLVGVEGLSFSTSAFMNAVDYT
KSRVQGLSVYPGADKQKSVAIINHPDVKRMLLTMKAYVEGCRSLAYFTSSCMDNAGVADGADRARWQGLVELLTPIVKAY
ITDNAWTVTALAMQCAGGYGYCSDYPFERLARDCKVTTIFEGTNGIQAMDLMFRKILGNNRVNFNNLLEMIDQTIEKGAA
DAEISVYAAIVKRAREGLARIVEEMAASSAAGNSLDLYAKTSPFLEAMGDVLLGWLHLWQLTVANPKLQGFIENKSEDEI
AKILNKNKNAAFYDGKVLGARFFIGTLLMNTFGKFEQIRSGAAPVISIGEKSFTG
>Mature_614_residues
ANLLVDKRDQIFVLKEMLEIDRLCSFPRYASHAGYEMVLNEAHTFANTELSPTAVDGDQQGCLYDPKTKAVTFPQSFHKP
YQKFCEGGWLTMCDSPDVGGDGFPSAVGTAVSEVFYACGFYIYGAAELTHAAAKVIEAYGSEEQKKSYMTKLFAGEWMGT
MCLTEPDAGSEVGAVQTVATRNGDGSYAITGTKIFITAGEHDLAGNIIHMVLARVAGDPPGTKGLSLFIVPKFLPDGVGN
AGERNDVYCTGIEHKMGLHGLVTCTMAFGDSGKCTGYLLGEQGKGMAEMFHMMNEQRLLVGVEGLSFSTSAFMNAVDYTK
SRVQGLSVYPGADKQKSVAIINHPDVKRMLLTMKAYVEGCRSLAYFTSSCMDNAGVADGADRARWQGLVELLTPIVKAYI
TDNAWTVTALAMQCAGGYGYCSDYPFERLARDCKVTTIFEGTNGIQAMDLMFRKILGNNRVNFNNLLEMIDQTIEKGAAD
AEISVYAAIVKRAREGLARIVEEMAASSAAGNSLDLYAKTSPFLEAMGDVLLGWLHLWQLTVANPKLQGFIENKSEDEIA
KILNKNKNAAFYDGKVLGARFFIGTLLMNTFGKFEQIRSGAAPVISIGEKSFTG

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=414, Percent_Identity=28.2608695652174, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI4501859, Length=320, Percent_Identity=29.375, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4557233, Length=417, Percent_Identity=26.1390887290168, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI7656849, Length=416, Percent_Identity=25.4807692307692, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI4501857, Length=364, Percent_Identity=26.0989010989011, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=313, Percent_Identity=28.7539936102236, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI76496475, Length=313, Percent_Identity=28.7539936102236, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI226958412, Length=311, Percent_Identity=27.0096463022508, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI226958414, Length=311, Percent_Identity=27.0096463022508, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI4557231, Length=410, Percent_Identity=25.609756097561, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI187960098, Length=410, Percent_Identity=25.609756097561, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI87082384, Length=344, Percent_Identity=28.7790697674419, Blast_Score=116, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17533517, Length=436, Percent_Identity=26.605504587156, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=321, Percent_Identity=30.2180685358255, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=418, Percent_Identity=27.7511961722488, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=315, Percent_Identity=26.984126984127, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=367, Percent_Identity=26.4305177111717, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=310, Percent_Identity=26.4516129032258, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538396, Length=418, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI86563381, Length=365, Percent_Identity=26.027397260274, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=365, Percent_Identity=26.027397260274, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=353, Percent_Identity=25.7790368271955, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=350, Percent_Identity=25.1428571428571, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=318, Percent_Identity=26.1006289308176, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=188, Percent_Identity=30.8510638297872, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=233, Percent_Identity=26.6094420600858, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=294, Percent_Identity=25.5102040816327, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356377, Length=422, Percent_Identity=26.0663507109005, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24660351, Length=448, Percent_Identity=26.7857142857143, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24646207, Length=420, Percent_Identity=25.2380952380952, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363737, Length=317, Percent_Identity=29.6529968454259, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24666513, Length=309, Percent_Identity=27.1844660194175, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355753, Length=408, Percent_Identity=26.4705882352941, Blast_Score=96, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 66741; Mature: 66610

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLLVDKRDQIFVLKEMLEIDRLCSFPRYASHAGYEMVLNEAHTFANTELSPTAVDGDQ
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCC
QGCLYDPKTKAVTFPQSFHKPYQKFCEGGWLTMCDSPDVGGDGFPSAVGTAVSEVFYACG
CCCEECCCCCEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
FYIYGAAELTHAAAKVIEAYGSEEQKKSYMTKLFAGEWMGTMCLTEPDAGSEVGAVQTVA
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEE
TRNGDGSYAITGTKIFITAGEHDLAGNIIHMVLARVAGDPPGTKGLSLFIVPKFLPDGVG
EECCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCC
NAGERNDVYCTGIEHKMGLHGLVTCTMAFGDSGKCTGYLLGEQGKGMAEMFHMMNEQRLL
CCCCCCCEEEECCCHHCCCHHHEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCEEE
VGVEGLSFSTSAFMNAVDYTKSRVQGLSVYPGADKQKSVAIINHPDVKRMLLTMKAYVEG
EEECCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHH
CRSLAYFTSSCMDNAGVADGADRARWQGLVELLTPIVKAYITDNAWTVTALAMQCAGGYG
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
YCSDYPFERLARDCKVTTIFEGTNGIQAMDLMFRKILGNNRVNFNNLLEMIDQTIEKGAA
CCCCCCHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
DAEISVYAAIVKRAREGLARIVEEMAASSAAGNSLDLYAKTSPFLEAMGDVLLGWLHLWQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LTVANPKLQGFIENKSEDEIAKILNKNKNAAFYDGKVLGARFFIGTLLMNTFGKFEQIRS
HHCCCCHHHHEECCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
GAAPVISIGEKSFTG
CCCCEEECCCCCCCC
>Mature Secondary Structure 
ANLLVDKRDQIFVLKEMLEIDRLCSFPRYASHAGYEMVLNEAHTFANTELSPTAVDGDQ
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCC
QGCLYDPKTKAVTFPQSFHKPYQKFCEGGWLTMCDSPDVGGDGFPSAVGTAVSEVFYACG
CCCEECCCCCEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
FYIYGAAELTHAAAKVIEAYGSEEQKKSYMTKLFAGEWMGTMCLTEPDAGSEVGAVQTVA
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEE
TRNGDGSYAITGTKIFITAGEHDLAGNIIHMVLARVAGDPPGTKGLSLFIVPKFLPDGVG
EECCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCC
NAGERNDVYCTGIEHKMGLHGLVTCTMAFGDSGKCTGYLLGEQGKGMAEMFHMMNEQRLL
CCCCCCCEEEECCCHHCCCHHHEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCEEE
VGVEGLSFSTSAFMNAVDYTKSRVQGLSVYPGADKQKSVAIINHPDVKRMLLTMKAYVEG
EEECCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHH
CRSLAYFTSSCMDNAGVADGADRARWQGLVELLTPIVKAYITDNAWTVTALAMQCAGGYG
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
YCSDYPFERLARDCKVTTIFEGTNGIQAMDLMFRKILGNNRVNFNNLLEMIDQTIEKGAA
CCCCCCHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
DAEISVYAAIVKRAREGLARIVEEMAASSAAGNSLDLYAKTSPFLEAMGDVLLGWLHLWQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LTVANPKLQGFIENKSEDEIAKILNKNKNAAFYDGKVLGARFFIGTLLMNTFGKFEQIRS
HHCCCCHHHHEECCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
GAAPVISIGEKSFTG
CCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]