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The map label for this gene is argK [C]

Identifier: 78223415

GI number: 78223415

Start: 2500723

End: 2501715

Strand: Reverse

Name: argK [C]

Synonym: Gmet_2210

Alternate gene names: 78223415

Gene position: 2501715-2500723 (Counterclockwise)

Preceding gene: 78223416

Following gene: 78223414

Centisome position: 62.58

GC content: 51.26

Gene sequence:

>993_bases
TTGAAAACCCTGGACAGATCCATTTCCCGGCTGATCTCCCTGCTCGAACGGCGGAATCCGGAAGGGATCGAGGAGTTGAA
AGGTCTCTACTGCAAATGCGGCAGAGCTCATGTCATCGGGATAACCGGACCACCGGGGGCAGGGAAAAGTTGCCTGGTTG
CAGCACTCGTCAGGGAGATAAGAAGGCGCGGAAAAACAGTAGGTGTTCTGGCAGTCGATCCATCCAGCCCGTTTAGCGAC
GGAGCAATCCTTGGCGACCGTGCCAGGATGACAGAGTTCTCAGGCGACAACGGGGTATTTATTCGTTCTTTCTCAGCTCG
AGGCGCCAGCGGTGGGTTGGCACCAGTGATCAACGATGCGGTCGATGTGCTCGATGCCTTTGGCAAGGAGGTCATCATTG
TTGAAACCGTGGGGGTCGGTCAGGTGGAGATGGATATTGCCAAGATTGCCCATACGGTGGTTCTGACCCTGGTTCCGGGA
TACGGGGATTCCCTCCAGGCGATGAAGGCCGGAATCCTGGAGATCGGCGATATCCTGGTGGTGAATAAGTCTGATCAGCC
GGGTGCGGATGGAGCGGTAAACGATTTAAGTTTCGAGATGCCGGTCACCTATGGGGGGAAAGAGTTTCAGTGTGCAAACA
TCAAGGCCGATCAATGGGGAGTACCGATTGCCAAAGTGTCTGCGTTGAAGGGAGATGGAGTAGAAGACCTTGTAACGGTG
ATTTTTGAGCACCTGATGTTTATAACGGAACGGAATATTTTTACCGGCATATGTCAAAAACGAAGAAGCAGGCAATTTCT
GGACATTCTTACACAGCAGGTGAGGGACAGATTCTTGGAAACATTGAAAACAGATAGGGATCTGCAGAAGTGGATCAACA
AAATAGAGAATCTGAAACTTGATCCATACAGTGCATCTGAACAGGTTGTTGATCTCGTTGAAAAAGCGAGAATCCTTGCA
GACAATGGCACGACGCCACGGAACAACAGATAG

Upstream 100 bases:

>100_bases
CCCAGTTCTTTATCGGCAATATCCTGCCGGTCACCGACGGCAAAATAGCCGCTCTTGCCTGGGGCGACGTCTCGGCCTGG
GAGGCGGTGGACAAATCGTT

Downstream 100 bases:

>100_bases
TCGACAAAATATCCTGGAATTAAGCTTCATGCCGACGCCACGGGTTCCCGCCCCATACGAATAGAAACGGAGGAGTAAAT
ATGAGTAGTCCTGTTGCTAA

Product: ArgK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKTLDRSISRLISLLERRNPEGIEELKGLYCKCGRAHVIGITGPPGAGKSCLVAALVREIRRRGKTVGVLAVDPSSPFSD
GAILGDRARMTEFSGDNGVFIRSFSARGASGGLAPVINDAVDVLDAFGKEVIIVETVGVGQVEMDIAKIAHTVVLTLVPG
YGDSLQAMKAGILEIGDILVVNKSDQPGADGAVNDLSFEMPVTYGGKEFQCANIKADQWGVPIAKVSALKGDGVEDLVTV
IFEHLMFITERNIFTGICQKRRSRQFLDILTQQVRDRFLETLKTDRDLQKWINKIENLKLDPYSASEQVVDLVEKARILA
DNGTTPRNNR

Sequences:

>Translated_330_residues
MKTLDRSISRLISLLERRNPEGIEELKGLYCKCGRAHVIGITGPPGAGKSCLVAALVREIRRRGKTVGVLAVDPSSPFSD
GAILGDRARMTEFSGDNGVFIRSFSARGASGGLAPVINDAVDVLDAFGKEVIIVETVGVGQVEMDIAKIAHTVVLTLVPG
YGDSLQAMKAGILEIGDILVVNKSDQPGADGAVNDLSFEMPVTYGGKEFQCANIKADQWGVPIAKVSALKGDGVEDLVTV
IFEHLMFITERNIFTGICQKRRSRQFLDILTQQVRDRFLETLKTDRDLQKWINKIENLKLDPYSASEQVVDLVEKARILA
DNGTTPRNNR
>Mature_330_residues
MKTLDRSISRLISLLERRNPEGIEELKGLYCKCGRAHVIGITGPPGAGKSCLVAALVREIRRRGKTVGVLAVDPSSPFSD
GAILGDRARMTEFSGDNGVFIRSFSARGASGGLAPVINDAVDVLDAFGKEVIIVETVGVGQVEMDIAKIAHTVVLTLVPG
YGDSLQAMKAGILEIGDILVVNKSDQPGADGAVNDLSFEMPVTYGGKEFQCANIKADQWGVPIAKVSALKGDGVEDLVTV
IFEHLMFITERNIFTGICQKRRSRQFLDILTQQVRDRFLETLKTDRDLQKWINKIENLKLDPYSASEQVVDLVEKARILA
DNGTTPRNNR

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=268, Percent_Identity=33.2089552238806, Blast_Score=138, Evalue=6e-33,
Organism=Escherichia coli, GI1789285, Length=316, Percent_Identity=28.7974683544304, Blast_Score=149, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71994271, Length=325, Percent_Identity=29.8461538461538, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71994275, Length=298, Percent_Identity=30.8724832214765, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35909; Mature: 35909

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLDRSISRLISLLERRNPEGIEELKGLYCKCGRAHVIGITGPPGAGKSCLVAALVREI
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHH
RRRGKTVGVLAVDPSSPFSDGAILGDRARMTEFSGDNGVFIRSFSARGASGGLAPVINDA
HHCCCEEEEEEECCCCCCCCCCEECCCHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHH
VDVLDAFGKEVIIVETVGVGQVEMDIAKIAHTVVLTLVPGYGDSLQAMKAGILEIGDILV
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCEEE
VNKSDQPGADGAVNDLSFEMPVTYGGKEFQCANIKADQWGVPIAKVSALKGDGVEDLVTV
EECCCCCCCCCCCCCCEEECCEEECCCEEEEECCCCCCCCCCHHHHHHCCCCCHHHHHHH
IFEHLMFITERNIFTGICQKRRSRQFLDILTQQVRDRFLETLKTDRDLQKWINKIENLKL
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
DPYSASEQVVDLVEKARILADNGTTPRNNR
CCCCCHHHHHHHHHHHHHEECCCCCCCCCC
>Mature Secondary Structure
MKTLDRSISRLISLLERRNPEGIEELKGLYCKCGRAHVIGITGPPGAGKSCLVAALVREI
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHH
RRRGKTVGVLAVDPSSPFSDGAILGDRARMTEFSGDNGVFIRSFSARGASGGLAPVINDA
HHCCCEEEEEEECCCCCCCCCCEECCCHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHH
VDVLDAFGKEVIIVETVGVGQVEMDIAKIAHTVVLTLVPGYGDSLQAMKAGILEIGDILV
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCEEE
VNKSDQPGADGAVNDLSFEMPVTYGGKEFQCANIKADQWGVPIAKVSALKGDGVEDLVTV
EECCCCCCCCCCCCCCEEECCEEECCCEEEEECCCCCCCCCCHHHHHHCCCCCHHHHHHH
IFEHLMFITERNIFTGICQKRRSRQFLDILTQQVRDRFLETLKTDRDLQKWINKIENLKL
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
DPYSASEQVVDLVEKARILADNGTTPRNNR
CCCCCHHHHHHHHHHHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]