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The map label for this gene is mmgC [H]

Identifier: 78223416

GI number: 78223416

Start: 2501712

End: 2503559

Strand: Reverse

Name: mmgC [H]

Synonym: Gmet_2211

Alternate gene names: 78223416

Gene position: 2503559-2501712 (Counterclockwise)

Preceding gene: 78223417

Following gene: 78223415

Centisome position: 62.63

GC content: 54.49

Gene sequence:

>1848_bases
ATGGCAAATCTGTTAGTCGATGAACGTGATGTGAAATTCGCCCTTTTTGAGCAGTTAAAAGTCCAGGACCTGTGTGCGTC
CGACCGTTTTTCCGGATGGAACGAGAAAGTCCTGGGATTGCTGCTTTCAGAGGCGAGCAAGTTTGCCGAAAAGGTGTTGT
TCCCGCTGAATATCGAAGGGGACAAGGTCGGTGCCCGCTTTGAGGGGGGAGAAGTTTATTCGGTTCCCGGTACGGCAGAG
GCTTACCAGAGCTTCGTTGAGAACGGCTGGCTCACTGCTTGCGAAGAGGAGACCCTTGGCGGCCAGGGACTCCCCCATGT
CATCAAGAATGCGGCCCATGAGATGTTCTTTGCCGCCAACTTCCCGTTCATGTGCTACGTCAACCTTACTCACGATGCCG
CCAAACTCATTGAACTTTTCGGCTCGGAACAGCAGAAGAGTCAGTATCTGCACAAGATGTACGGGGGTGAGTGGCTCGGC
ACGATGGCCCTGACGGAACCTGCGGCGGGTTCGGACGTGGGGAACATCGAGTTCAAGGCGACGAGAAACACGGATGGTAC
CTATTCGCTGGTTGGTCAGAAGATATTCATTACCAACGGCGACAGCGACGTGTGTGAGAACACGGTACATATGGTTCTAG
CCAGGATTGAAGGGGATCCGGCGGGGACCAAGGGGTTGTCGATCTTTATTGTTCCCAAATTCAAGATCAATTCTGACGGA
TCTCTAGGGGAGGCGAACGACGTCAAGTGTATTGGCATCGAACACAAGATGGGGATCAAGGCATCGCCGACCACTACCAT
GTCGTTTGGCGAAAAGGGGTGCTGCACTGGCTACCTCCTTGGCAAGGAGCAGGATGGCATCAAGATCATGTTCCACATGA
TGAATGCCTCGCGGCTCGAGGTGGGGATGTGGGGCCAGGGGACCTGCTCGGTTTCCTACATGCATGCACTGAGGTACGCC
CTGGAGAGACGGCAGGGTCAGAGTATCGCTGATCCGGATTCCGGACAGGTTCCGATTATTCACCATCCTGATATTCGTCG
TACGCTCCTCATGATGAAATCGTACATTCAGGGGATGCGGGCGATGCTCTATTACTGCGGCTACGCCATGGACCGGATGG
CAGTCGTCGACAACGAGGAAGAGAAAAAGAAGCTGCAGGGGATTGTCGATTTGCTGATACCGCTCTGCAAGGCTTACCCC
ACGGAGAAGGGGGTGGAATTCGCTTCCCACGCCATCCAGGTATATGGGGGATACGGTTATACCCAGGAGTATCCGGTCGA
ACAGTTCATGCGGGATTCCAAAGTTGCCTGCATTTTCGAGGGGACAACGGGAATACAGGCAATGGACCTGGCTTTGCGTA
AGATCAGGATGAAAAAGGGGCAGGTCTTTGCGGAATTCCTGAAGGATATGGATGGGATGGTAAACCGTGCAGCAGAACTG
CCCGGCTTGAAGAAGCATATCGAGCAGTTCGAGCGCACGAAATCAGCTCTGGCGGGTATACCGGCCCACCTTGCCGAAGG
GGCCGAAGCAAACGGAGTGCACTATTCCTATCTCAAGGCGACCCCTTTCCTGGAGGCCTTCGGGGATGTGGTTGTGGCGT
GGTTTCTCCTTTGGGGCGCAGTGGTTGCGCACGGGCAACTCGAGGAACTGTTTCTCAAGAAGAAGCTTGAAGATGCGGAG
AGCAGGAAGTCATTCATTCAGAAGAACACGGACGCTGCCTTTCTGGACGGAAAAATCAGGAGCGCCCAGTTCTTTATCGG
CAATATCCTGCCGGTCACCGACGGCAAAATAGCCGCTCTTGCCTGGGGCGACGTCTCGGCCTGGGAGGCGGTGGACAAAT
CGTTTTGA

Upstream 100 bases:

>100_bases
CAGGAAGGGACTCTGGCCTTCCTGGAAAAGCGCAAGCCGGTCTTCAACAAGGGTTAGTAGACACAGGTGTTCAATCCTCC
ACAAAAGAAAGACGGATGCC

Downstream 100 bases:

>100_bases
AAACCCTGGACAGATCCATTTCCCGGCTGATCTCCCTGCTCGAACGGCGGAATCCGGAAGGGATCGAGGAGTTGAAAGGT
CTCTACTGCAAATGCGGCAG

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MANLLVDERDVKFALFEQLKVQDLCASDRFSGWNEKVLGLLLSEASKFAEKVLFPLNIEGDKVGARFEGGEVYSVPGTAE
AYQSFVENGWLTACEEETLGGQGLPHVIKNAAHEMFFAANFPFMCYVNLTHDAAKLIELFGSEQQKSQYLHKMYGGEWLG
TMALTEPAAGSDVGNIEFKATRNTDGTYSLVGQKIFITNGDSDVCENTVHMVLARIEGDPAGTKGLSIFIVPKFKINSDG
SLGEANDVKCIGIEHKMGIKASPTTTMSFGEKGCCTGYLLGKEQDGIKIMFHMMNASRLEVGMWGQGTCSVSYMHALRYA
LERRQGQSIADPDSGQVPIIHHPDIRRTLLMMKSYIQGMRAMLYYCGYAMDRMAVVDNEEEKKKLQGIVDLLIPLCKAYP
TEKGVEFASHAIQVYGGYGYTQEYPVEQFMRDSKVACIFEGTTGIQAMDLALRKIRMKKGQVFAEFLKDMDGMVNRAAEL
PGLKKHIEQFERTKSALAGIPAHLAEGAEANGVHYSYLKATPFLEAFGDVVVAWFLLWGAVVAHGQLEELFLKKKLEDAE
SRKSFIQKNTDAAFLDGKIRSAQFFIGNILPVTDGKIAALAWGDVSAWEAVDKSF

Sequences:

>Translated_615_residues
MANLLVDERDVKFALFEQLKVQDLCASDRFSGWNEKVLGLLLSEASKFAEKVLFPLNIEGDKVGARFEGGEVYSVPGTAE
AYQSFVENGWLTACEEETLGGQGLPHVIKNAAHEMFFAANFPFMCYVNLTHDAAKLIELFGSEQQKSQYLHKMYGGEWLG
TMALTEPAAGSDVGNIEFKATRNTDGTYSLVGQKIFITNGDSDVCENTVHMVLARIEGDPAGTKGLSIFIVPKFKINSDG
SLGEANDVKCIGIEHKMGIKASPTTTMSFGEKGCCTGYLLGKEQDGIKIMFHMMNASRLEVGMWGQGTCSVSYMHALRYA
LERRQGQSIADPDSGQVPIIHHPDIRRTLLMMKSYIQGMRAMLYYCGYAMDRMAVVDNEEEKKKLQGIVDLLIPLCKAYP
TEKGVEFASHAIQVYGGYGYTQEYPVEQFMRDSKVACIFEGTTGIQAMDLALRKIRMKKGQVFAEFLKDMDGMVNRAAEL
PGLKKHIEQFERTKSALAGIPAHLAEGAEANGVHYSYLKATPFLEAFGDVVVAWFLLWGAVVAHGQLEELFLKKKLEDAE
SRKSFIQKNTDAAFLDGKIRSAQFFIGNILPVTDGKIAALAWGDVSAWEAVDKSF
>Mature_614_residues
ANLLVDERDVKFALFEQLKVQDLCASDRFSGWNEKVLGLLLSEASKFAEKVLFPLNIEGDKVGARFEGGEVYSVPGTAEA
YQSFVENGWLTACEEETLGGQGLPHVIKNAAHEMFFAANFPFMCYVNLTHDAAKLIELFGSEQQKSQYLHKMYGGEWLGT
MALTEPAAGSDVGNIEFKATRNTDGTYSLVGQKIFITNGDSDVCENTVHMVLARIEGDPAGTKGLSIFIVPKFKINSDGS
LGEANDVKCIGIEHKMGIKASPTTTMSFGEKGCCTGYLLGKEQDGIKIMFHMMNASRLEVGMWGQGTCSVSYMHALRYAL
ERRQGQSIADPDSGQVPIIHHPDIRRTLLMMKSYIQGMRAMLYYCGYAMDRMAVVDNEEEKKKLQGIVDLLIPLCKAYPT
EKGVEFASHAIQVYGGYGYTQEYPVEQFMRDSKVACIFEGTTGIQAMDLALRKIRMKKGQVFAEFLKDMDGMVNRAAELP
GLKKHIEQFERTKSALAGIPAHLAEGAEANGVHYSYLKATPFLEAFGDVVVAWFLLWGAVVAHGQLEELFLKKKLEDAES
RKSFIQKNTDAAFLDGKIRSAQFFIGNILPVTDGKIAALAWGDVSAWEAVDKSF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=322, Percent_Identity=29.1925465838509, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI7656849, Length=352, Percent_Identity=26.1363636363636, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI4557231, Length=424, Percent_Identity=26.6509433962264, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI187960098, Length=424, Percent_Identity=26.6509433962264, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4557233, Length=423, Percent_Identity=26.4775413711584, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI226958412, Length=310, Percent_Identity=27.741935483871, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI226958414, Length=310, Percent_Identity=27.741935483871, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI4557235, Length=336, Percent_Identity=29.1666666666667, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI76496475, Length=337, Percent_Identity=29.3768545994065, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4501857, Length=322, Percent_Identity=27.639751552795, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4501859, Length=321, Percent_Identity=25.5451713395639, Blast_Score=88, Evalue=3e-17,
Organism=Escherichia coli, GI87082384, Length=313, Percent_Identity=28.4345047923323, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786223, Length=311, Percent_Identity=23.1511254019293, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081958, Length=311, Percent_Identity=27.3311897106109, Blast_Score=66, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=404, Percent_Identity=25, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=318, Percent_Identity=26.7295597484277, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=316, Percent_Identity=27.5316455696203, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=420, Percent_Identity=25, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=312, Percent_Identity=27.8846153846154, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=326, Percent_Identity=28.5276073619632, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=427, Percent_Identity=26.9320843091335, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=400, Percent_Identity=24.75, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=400, Percent_Identity=24, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=240, Percent_Identity=28.75, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=313, Percent_Identity=26.8370607028754, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71990804, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24660351, Length=460, Percent_Identity=26.304347826087, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281363737, Length=330, Percent_Identity=31.5151515151515, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355753, Length=371, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=27.2479564032698, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646207, Length=382, Percent_Identity=24.0837696335079, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 67959; Mature: 67828

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLLVDERDVKFALFEQLKVQDLCASDRFSGWNEKVLGLLLSEASKFAEKVLFPLNIEG
CCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCC
DKVGARFEGGEVYSVPGTAEAYQSFVENGWLTACEEETLGGQGLPHVIKNAAHEMFFAAN
CCCCCEECCCEEEECCCCHHHHHHHHHCCCEEEECHHCCCCCCCHHHHHHHHHHEEEEEC
FPFMCYVNLTHDAAKLIELFGSEQQKSQYLHKMYGGEWLGTMALTEPAAGSDVGNIEFKA
CCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEHEECCCCCCCCCCCEEEEE
TRNTDGTYSLVGQKIFITNGDSDVCENTVHMVLARIEGDPAGTKGLSIFIVPKFKINSDG
ECCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCC
SLGEANDVKCIGIEHKMGIKASPTTTMSFGEKGCCTGYLLGKEQDGIKIMFHMMNASRLE
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEE
VGMWGQGTCSVSYMHALRYALERRQGQSIADPDSGQVPIIHHPDIRRTLLMMKSYIQGMR
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
AMLYYCGYAMDRMAVVDNEEEKKKLQGIVDLLIPLCKAYPTEKGVEFASHAIQVYGGYGY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEEECCCC
TQEYPVEQFMRDSKVACIFEGTTGIQAMDLALRKIRMKKGQVFAEFLKDMDGMVNRAAEL
CCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGLKKHIEQFERTKSALAGIPAHLAEGAEANGVHYSYLKATPFLEAFGDVVVAWFLLWGA
CCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
VVAHGQLEELFLKKKLEDAESRKSFIQKNTDAAFLDGKIRSAQFFIGNILPVTDGKIAAL
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCEEECCCCCEEEE
AWGDVSAWEAVDKSF
EECCCHHHHHHHCCC
>Mature Secondary Structure 
ANLLVDERDVKFALFEQLKVQDLCASDRFSGWNEKVLGLLLSEASKFAEKVLFPLNIEG
CCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCC
DKVGARFEGGEVYSVPGTAEAYQSFVENGWLTACEEETLGGQGLPHVIKNAAHEMFFAAN
CCCCCEECCCEEEECCCCHHHHHHHHHCCCEEEECHHCCCCCCCHHHHHHHHHHEEEEEC
FPFMCYVNLTHDAAKLIELFGSEQQKSQYLHKMYGGEWLGTMALTEPAAGSDVGNIEFKA
CCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEHEECCCCCCCCCCCEEEEE
TRNTDGTYSLVGQKIFITNGDSDVCENTVHMVLARIEGDPAGTKGLSIFIVPKFKINSDG
ECCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCC
SLGEANDVKCIGIEHKMGIKASPTTTMSFGEKGCCTGYLLGKEQDGIKIMFHMMNASRLE
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEE
VGMWGQGTCSVSYMHALRYALERRQGQSIADPDSGQVPIIHHPDIRRTLLMMKSYIQGMR
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
AMLYYCGYAMDRMAVVDNEEEKKKLQGIVDLLIPLCKAYPTEKGVEFASHAIQVYGGYGY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEEECCCC
TQEYPVEQFMRDSKVACIFEGTTGIQAMDLALRKIRMKKGQVFAEFLKDMDGMVNRAAEL
CCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGLKKHIEQFERTKSALAGIPAHLAEGAEANGVHYSYLKATPFLEAFGDVVVAWFLLWGA
CCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
VVAHGQLEELFLKKKLEDAESRKSFIQKNTDAAFLDGKIRSAQFFIGNILPVTDGKIAAL
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCEEECCCCCEEEE
AWGDVSAWEAVDKSF
EECCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]