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The map label for this gene is xylR [H]

Identifier: 78223323

GI number: 78223323

Start: 2382728

End: 2384467

Strand: Reverse

Name: xylR [H]

Synonym: Gmet_2116

Alternate gene names: 78223323

Gene position: 2384467-2382728 (Counterclockwise)

Preceding gene: 78223348

Following gene: 78223322

Centisome position: 59.65

GC content: 60.34

Gene sequence:

>1740_bases
ATGTACAAATATTCCGGTAAAACCAGGCCGGTCCGCGACACGAACGACACGGATCTGCGCTCGCGCTTGAGGTTCTGTGT
CGAAACCGGCCAGATATGGCTGCACGAGCATCGCATGCTCCTGATCCATGCCGAGGTCCAGGCGTCGCTACGCAAGGAGT
TGATCGACACCCTCGGCATGGACCGTGCCCGGGGGCTTCTCACCCGCATGGGGTACGCGGCAGGGATGCGCGACTTCGAG
CTGGCCCGCACCAGGGCCGGAAGCGATGGCGATGTGGAGGCGTTCATTGCCGGCCCGCAGTTGCACATGCTGGAAGGCAT
CGCCAAGGTGTCCACGGTCTCGCTGGAGTACGACCGCAGCGCCGGCAGCTTCTATGCCGAGTTCATCTGGGAGAACTCCT
GGGAGAGCGAGTGGCACAAACAGTACTACGGCACCTACTCCGAGCCGGTCTGCTGGAGCCAGATAGGGTATGCCTGCGCC
TATGCGTCATCCTTCATGGGACGCCCCATTCTCTACAAGGAACTGGAGTGCGCGGGCATGGGGGAAGGTCATTGCCGCAT
CGTTGGAAAGCCCCTTGAGGAGTGGGAAGACGCATCGGAATATTCGCGCTTTTTCGTCAAGGAGTCCATTGCCGAGCAGC
TGATCGATCTGCAGACCCAGGTGGTCCAGCTCCGTTCGGTCATCGGTGAAAAAGAGAAACTCCCTGCGGACATTGTCGGC
AATTCCAGGGCATTCCGTGCGGCCTACGACATGCTGCAGCAGGCGGCCAAAAGCCAGATAACGGTCCTGCTGCTCGGCGA
GACCGGCTCCGGCAAGGAGGTCTTCGCCCGGGCGCTGCACTCCCGCAGCACTCGCCGCAATGAATCGTTCATCGCCATCA
ACTGCGCCGCCATCCCCCACGACCTGGTGGAATCGGAGCTGTTCGGGGTGGAGAAGGGGGCCTATACCGGTGCGCTCAGT
GCCCGGCCGGGACGCTTCGAGCGGGCCAATGGAGGCACGCTGTTTCTCGACGAGATCGGTGATCTGCCGCTGTCGGCCCA
GGCCAAGCTGCTGCGGGTTCTTCAGGAAGGTGAAATCGAGCGGCTTGGGGACCACAAAGTCCGCAAGGTAGATGTGAGGC
TGGTCGCGGCCACCAACATCGACCTGAAACAACTGGTCAAGGAGGGTAAGTTCCGGTCGGATCTCTACTATCGGCTCAAT
GCCTTCCAGATCAACATCCCTCCTCTCCGGGAGCGCAAAGAGGACATCCCTCTCTTGGCCCAAAGGTTCATTGAGAAATA
TTCCGCCATCCACGGCAAGAAACTTAACGGCTTTACCGATAAGGCCATGCGGGCCATCTTGGCCTACCCCTGGCCGGGGA
ACATCCGCGAATTGCTGAACATGGTGGAGCGGGGGGTCATTCTTACCCCCAATGGCACCCGGATCGAGCTAGAGCAGATG
TTCTCCTCCAGCAGCATTGATATGGCCATGGAATTCGGCCTCGATAGTAACGGCGGTCTCGGTGCCGATACCCCGGAACC
CGTGAATGATATCTACGAATTTGTGGTTAAAGGGAACATGACTCTGGACCAGGTTGAGGCCACCCTGATCGAATCGGCCG
TAAAAACGGCCAACGGCAACCTTTCGGCGGCGGCACGGACGCTTGGCGTGACCCGGCCGCAACTGGCCTACCGACTCAGA
CGTCTGCAGGAGAATAACGTGGCGCCTGCCGGCGTTGCCCTGGCAGCCGTTCCGGAGTGA

Upstream 100 bases:

>100_bases
GGCGGGCGGTTACATCGTGACTGCCGACCATATGTACTGGACAAATATACATGTCTGGTATAACTTGGTTTTATATAATT
TTCGGCGGTAGGTATTTTTC

Downstream 100 bases:

>100_bases
GGTGGCGAGGAGCACGCCATGCAAACCAAAGTTACCGAAAATTTTCTCAATAGATTTCGAAGCAACAGATCCCGCCTGAA
AGACGAGGCGTTTCTCCAAA

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MYKYSGKTRPVRDTNDTDLRSRLRFCVETGQIWLHEHRMLLIHAEVQASLRKELIDTLGMDRARGLLTRMGYAAGMRDFE
LARTRAGSDGDVEAFIAGPQLHMLEGIAKVSTVSLEYDRSAGSFYAEFIWENSWESEWHKQYYGTYSEPVCWSQIGYACA
YASSFMGRPILYKELECAGMGEGHCRIVGKPLEEWEDASEYSRFFVKESIAEQLIDLQTQVVQLRSVIGEKEKLPADIVG
NSRAFRAAYDMLQQAAKSQITVLLLGETGSGKEVFARALHSRSTRRNESFIAINCAAIPHDLVESELFGVEKGAYTGALS
ARPGRFERANGGTLFLDEIGDLPLSAQAKLLRVLQEGEIERLGDHKVRKVDVRLVAATNIDLKQLVKEGKFRSDLYYRLN
AFQINIPPLRERKEDIPLLAQRFIEKYSAIHGKKLNGFTDKAMRAILAYPWPGNIRELLNMVERGVILTPNGTRIELEQM
FSSSSIDMAMEFGLDSNGGLGADTPEPVNDIYEFVVKGNMTLDQVEATLIESAVKTANGNLSAAARTLGVTRPQLAYRLR
RLQENNVAPAGVALAAVPE

Sequences:

>Translated_579_residues
MYKYSGKTRPVRDTNDTDLRSRLRFCVETGQIWLHEHRMLLIHAEVQASLRKELIDTLGMDRARGLLTRMGYAAGMRDFE
LARTRAGSDGDVEAFIAGPQLHMLEGIAKVSTVSLEYDRSAGSFYAEFIWENSWESEWHKQYYGTYSEPVCWSQIGYACA
YASSFMGRPILYKELECAGMGEGHCRIVGKPLEEWEDASEYSRFFVKESIAEQLIDLQTQVVQLRSVIGEKEKLPADIVG
NSRAFRAAYDMLQQAAKSQITVLLLGETGSGKEVFARALHSRSTRRNESFIAINCAAIPHDLVESELFGVEKGAYTGALS
ARPGRFERANGGTLFLDEIGDLPLSAQAKLLRVLQEGEIERLGDHKVRKVDVRLVAATNIDLKQLVKEGKFRSDLYYRLN
AFQINIPPLRERKEDIPLLAQRFIEKYSAIHGKKLNGFTDKAMRAILAYPWPGNIRELLNMVERGVILTPNGTRIELEQM
FSSSSIDMAMEFGLDSNGGLGADTPEPVNDIYEFVVKGNMTLDQVEATLIESAVKTANGNLSAAARTLGVTRPQLAYRLR
RLQENNVAPAGVALAAVPE
>Mature_579_residues
MYKYSGKTRPVRDTNDTDLRSRLRFCVETGQIWLHEHRMLLIHAEVQASLRKELIDTLGMDRARGLLTRMGYAAGMRDFE
LARTRAGSDGDVEAFIAGPQLHMLEGIAKVSTVSLEYDRSAGSFYAEFIWENSWESEWHKQYYGTYSEPVCWSQIGYACA
YASSFMGRPILYKELECAGMGEGHCRIVGKPLEEWEDASEYSRFFVKESIAEQLIDLQTQVVQLRSVIGEKEKLPADIVG
NSRAFRAAYDMLQQAAKSQITVLLLGETGSGKEVFARALHSRSTRRNESFIAINCAAIPHDLVESELFGVEKGAYTGALS
ARPGRFERANGGTLFLDEIGDLPLSAQAKLLRVLQEGEIERLGDHKVRKVDVRLVAATNIDLKQLVKEGKFRSDLYYRLN
AFQINIPPLRERKEDIPLLAQRFIEKYSAIHGKKLNGFTDKAMRAILAYPWPGNIRELLNMVERGVILTPNGTRIELEQM
FSSSSIDMAMEFGLDSNGGLGADTPEPVNDIYEFVVKGNMTLDQVEATLIESAVKTANGNLSAAARTLGVTRPQLAYRLR
RLQENNVAPAGVALAAVPE

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=335, Percent_Identity=46.5671641791045, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1789087, Length=360, Percent_Identity=43.3333333333333, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1788550, Length=336, Percent_Identity=44.047619047619, Blast_Score=262, Evalue=5e-71,
Organism=Escherichia coli, GI1790437, Length=327, Percent_Identity=43.7308868501529, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI1790299, Length=338, Percent_Identity=41.4201183431953, Blast_Score=245, Evalue=6e-66,
Organism=Escherichia coli, GI1788905, Length=314, Percent_Identity=41.0828025477707, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789233, Length=318, Percent_Identity=40.5660377358491, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI87082152, Length=237, Percent_Identity=47.6793248945148, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=48.4848484848485, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI1786524, Length=381, Percent_Identity=34.6456692913386, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1787583, Length=245, Percent_Identity=40, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1789828, Length=233, Percent_Identity=40.343347639485, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI87081858, Length=379, Percent_Identity=29.5514511873351, Blast_Score=147, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 64707; Mature: 64707

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKYSGKTRPVRDTNDTDLRSRLRFCVETGQIWLHEHRMLLIHAEVQASLRKELIDTLGM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCEEEEEEHHHHHHHHHHHHHHHCC
DRARGLLTRMGYAAGMRDFELARTRAGSDGDVEAFIAGPQLHMLEGIAKVSTVSLEYDRS
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHEEEEEEECCC
AGSFYAEFIWENSWESEWHKQYYGTYSEPVCWSQIGYACAYASSFMGRPILYKELECAGM
CCHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
GEGHCRIVGKPLEEWEDASEYSRFFVKESIAEQLIDLQTQVVQLRSVIGEKEKLPADIVG
CCCCEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHCC
NSRAFRAAYDMLQQAAKSQITVLLLGETGSGKEVFARALHSRSTRRNESFIAINCAAIPH
CCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCH
DLVESELFGVEKGAYTGALSARPGRFERANGGTLFLDEIGDLPLSAQAKLLRVLQEGEIE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHH
RLGDHKVRKVDVRLVAATNIDLKQLVKEGKFRSDLYYRLNAFQINIPPLRERKEDIPLLA
HCCCCCEEEEEEEEEEECCCCHHHHHHCCCCCCCCEEEEEEEEECCCCHHHCCCCCHHHH
QRFIEKYSAIHGKKLNGFTDKAMRAILAYPWPGNIRELLNMVERGVILTPNGTRIELEQM
HHHHHHHHHHCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHCCEEECCCCCEEEHHHH
FSSSSIDMAMEFGLDSNGGLGADTPEPVNDIYEFVVKGNMTLDQVEATLIESAVKTANGN
HCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
LSAAARTLGVTRPQLAYRLRRLQENNVAPAGVALAAVPE
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCC
>Mature Secondary Structure
MYKYSGKTRPVRDTNDTDLRSRLRFCVETGQIWLHEHRMLLIHAEVQASLRKELIDTLGM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCEEEEEEHHHHHHHHHHHHHHHCC
DRARGLLTRMGYAAGMRDFELARTRAGSDGDVEAFIAGPQLHMLEGIAKVSTVSLEYDRS
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHEEEEEEECCC
AGSFYAEFIWENSWESEWHKQYYGTYSEPVCWSQIGYACAYASSFMGRPILYKELECAGM
CCHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
GEGHCRIVGKPLEEWEDASEYSRFFVKESIAEQLIDLQTQVVQLRSVIGEKEKLPADIVG
CCCCEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHCC
NSRAFRAAYDMLQQAAKSQITVLLLGETGSGKEVFARALHSRSTRRNESFIAINCAAIPH
CCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCH
DLVESELFGVEKGAYTGALSARPGRFERANGGTLFLDEIGDLPLSAQAKLLRVLQEGEIE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHH
RLGDHKVRKVDVRLVAATNIDLKQLVKEGKFRSDLYYRLNAFQINIPPLRERKEDIPLLA
HCCCCCEEEEEEEEEEECCCCHHHHHHCCCCCCCCEEEEEEEEECCCCHHHCCCCCHHHH
QRFIEKYSAIHGKKLNGFTDKAMRAILAYPWPGNIRELLNMVERGVILTPNGTRIELEQM
HHHHHHHHHHCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHCCEEECCCCCEEEHHHH
FSSSSIDMAMEFGLDSNGGLGADTPEPVNDIYEFVVKGNMTLDQVEATLIESAVKTANGN
HCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
LSAAARTLGVTRPQLAYRLRRLQENNVAPAGVALAAVPE
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]