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The map label for this gene is rsbU [H]

Identifier: 78223322

GI number: 78223322

Start: 2381099

End: 2382709

Strand: Reverse

Name: rsbU [H]

Synonym: Gmet_2115

Alternate gene names: 78223322

Gene position: 2382709-2381099 (Counterclockwise)

Preceding gene: 78223323

Following gene: 78223321

Centisome position: 59.61

GC content: 57.91

Gene sequence:

>1611_bases
ATGCAAACCAAAGTTACCGAAAATTTTCTCAATAGATTTCGAAGCAACAGATCCCGCCTGAAAGACGAGGCGTTTCTCCA
AAGCTACGCCCTGTTGAGTGTCGTCTTTGACGAAGCGTTTCAGTTGATGGGGCTCCTGAAGCCGGACGGCACCCTCATCA
AGATCAATAAAGCCGCCTTCCGTTCCATCAAGGGAAAGGAATCGGAAGTTATCGGCAGGCCCTTCTGGGACACTCCGTGG
TGGGCTCACTCCCGCGAAGAACAGAAGCGGGTGCGCGAGGGGATCGAGGCTGCTGCCCGGGGGGAGTTCATCCGCTTTGA
AACCACCCACGCGGCGACCCTTGACGGAAGAGTTGCGTACATAGATTTTTCGCTTAAGCCCGTGAAGGATGAGAGGGGGA
ATGTGGTCCTGGTCGTTCCGGAAGGGCGCGATATCACGGAACGACGGCGTGCGGAAGAGGCGTTGCGGGAGGCGGCAATC
AAATACCGGATCGTCGCCGACAACACCTTCAACTGGGAATTCTGGCTGAGCCCGGAAGGAAGGGTCATTTACACGTCTCC
TTCCTGCGAAAGGGTCTGCGGCTATGAGGCCGACGCGTTCACTGCCGATCCCGGCCTGATCTGGAATATCGTTCACCCCG
ATGATCGGCAGCTTGTGGACGTCCACCGGCATGAGGTGAGAGAAGAAAAGGTTATGGGCCAGGTTGAATTCCGCATCGTC
CACCGGGATGGTGATATCCGCTGGATTCGCCATGTCTGCCAGCCGGTGTTCGACGACAACGGTACCTACCTCGGCATCCG
GGGGAGCTTCTCCGACATCACCGAACAGAAAAAGGCCGCGGCCGCCCTCCTGGACAACGCCCGGATCACCCGGGAACTGG
AGATAGCCAAGGAGATCCAGCAGTCGTTCCTGCCGGTATGTCCCTCGGCGTTGCCGGGGGTGCTCATGGCGTGCTGTTGT
CACCCGGCGGCCCATGTGGGTGGCGATTACTACGATTTCTTCACCCTGGAAGAGGGCGCCATCGATATGGTCATCGCCGA
TGTCACCGGCCATAGCGTCGGCTCGTCCCTCCTGATGACCATGGCCCGCAGTGTGCTTAACGCCAAGGTCACCGGCAGCC
GCCCCCCCGGAAAGCTCCTCGAAGTGGTAAATGACCTGCTCCACGATGATCTCTCGCGGGCAGAGCTTCAGATCAGCATG
TTCTATATCCGGCTGGACATCCCCAACCACACCGTGTCCTACGCCAACGCCGGCCACAACCATCCCGTTCTCTACCGTTC
GGAGCAGGCTGATTTCATTGAACTCGATGCTGACGGAATGATCATGGGGGTAAAAAAAGAGGTCGGTTTCGAGGAAAAAA
CCATCCTGGTGGCGGCGGGGGACATCTTCATCCTCTATACCGACGGCGTAACGGAAGCGGAAAGTGCCGCGGGAGAGCCT
TTCGGCACCGGGCGGCTCTGCGAGGCCGTTGCCGCATACCGGGACAACCATCCGAAAGAGATCATGGCCGGGATTTTCCG
GAAATTGACCGAATTTACCGGCGACGGGCCTCTTGCTGACGATGTGGCGATGATTATTGTCAAAATTGCACCATCGGATG
AGGCACAGTAA

Upstream 100 bases:

>100_bases
GCAACTGGCCTACCGACTCAGACGTCTGCAGGAGAATAACGTGGCGCCTGCCGGCGTTGCCCTGGCAGCCGTTCCGGAGT
GAGGTGGCGAGGAGCACGCC

Downstream 100 bases:

>100_bases
CGATGACCAAACCCCGCGGTAACCGAAATATCGCCTGCGACGCAACCAACAGCGACCTGCGCTCACTGGTGCATTTCTGT
GCCGAAACCGGTCAGATATG

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MQTKVTENFLNRFRSNRSRLKDEAFLQSYALLSVVFDEAFQLMGLLKPDGTLIKINKAAFRSIKGKESEVIGRPFWDTPW
WAHSREEQKRVREGIEAAARGEFIRFETTHAATLDGRVAYIDFSLKPVKDERGNVVLVVPEGRDITERRRAEEALREAAI
KYRIVADNTFNWEFWLSPEGRVIYTSPSCERVCGYEADAFTADPGLIWNIVHPDDRQLVDVHRHEVREEKVMGQVEFRIV
HRDGDIRWIRHVCQPVFDDNGTYLGIRGSFSDITEQKKAAAALLDNARITRELEIAKEIQQSFLPVCPSALPGVLMACCC
HPAAHVGGDYYDFFTLEEGAIDMVIADVTGHSVGSSLLMTMARSVLNAKVTGSRPPGKLLEVVNDLLHDDLSRAELQISM
FYIRLDIPNHTVSYANAGHNHPVLYRSEQADFIELDADGMIMGVKKEVGFEEKTILVAAGDIFILYTDGVTEAESAAGEP
FGTGRLCEAVAAYRDNHPKEIMAGIFRKLTEFTGDGPLADDVAMIIVKIAPSDEAQ

Sequences:

>Translated_536_residues
MQTKVTENFLNRFRSNRSRLKDEAFLQSYALLSVVFDEAFQLMGLLKPDGTLIKINKAAFRSIKGKESEVIGRPFWDTPW
WAHSREEQKRVREGIEAAARGEFIRFETTHAATLDGRVAYIDFSLKPVKDERGNVVLVVPEGRDITERRRAEEALREAAI
KYRIVADNTFNWEFWLSPEGRVIYTSPSCERVCGYEADAFTADPGLIWNIVHPDDRQLVDVHRHEVREEKVMGQVEFRIV
HRDGDIRWIRHVCQPVFDDNGTYLGIRGSFSDITEQKKAAAALLDNARITRELEIAKEIQQSFLPVCPSALPGVLMACCC
HPAAHVGGDYYDFFTLEEGAIDMVIADVTGHSVGSSLLMTMARSVLNAKVTGSRPPGKLLEVVNDLLHDDLSRAELQISM
FYIRLDIPNHTVSYANAGHNHPVLYRSEQADFIELDADGMIMGVKKEVGFEEKTILVAAGDIFILYTDGVTEAESAAGEP
FGTGRLCEAVAAYRDNHPKEIMAGIFRKLTEFTGDGPLADDVAMIIVKIAPSDEAQ
>Mature_536_residues
MQTKVTENFLNRFRSNRSRLKDEAFLQSYALLSVVFDEAFQLMGLLKPDGTLIKINKAAFRSIKGKESEVIGRPFWDTPW
WAHSREEQKRVREGIEAAARGEFIRFETTHAATLDGRVAYIDFSLKPVKDERGNVVLVVPEGRDITERRRAEEALREAAI
KYRIVADNTFNWEFWLSPEGRVIYTSPSCERVCGYEADAFTADPGLIWNIVHPDDRQLVDVHRHEVREEKVMGQVEFRIV
HRDGDIRWIRHVCQPVFDDNGTYLGIRGSFSDITEQKKAAAALLDNARITRELEIAKEIQQSFLPVCPSALPGVLMACCC
HPAAHVGGDYYDFFTLEEGAIDMVIADVTGHSVGSSLLMTMARSVLNAKVTGSRPPGKLLEVVNDLLHDDLSRAELQISM
FYIRLDIPNHTVSYANAGHNHPVLYRSEQADFIELDADGMIMGVKKEVGFEEKTILVAAGDIFILYTDGVTEAESAAGEP
FGTGRLCEAVAAYRDNHPKEIMAGIFRKLTEFTGDGPLADDVAMIIVKIAPSDEAQ

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 60053; Mature: 60053

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTKVTENFLNRFRSNRSRLKDEAFLQSYALLSVVFDEAFQLMGLLKPDGTLIKINKAAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHH
RSIKGKESEVIGRPFWDTPWWAHSREEQKRVREGIEAAARGEFIRFETTHAATLDGRVAY
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCEEEE
IDFSLKPVKDERGNVVLVVPEGRDITERRRAEEALREAAIKYRIVADNTFNWEFWLSPEG
EEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCC
RVIYTSPSCERVCGYEADAFTADPGLIWNIVHPDDRQLVDVHRHEVREEKVMGQVEFRIV
EEEEECCCCHHHCCCCCCCEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEE
HRDGDIRWIRHVCQPVFDDNGTYLGIRGSFSDITEQKKAAAALLDNARITRELEIAKEIQ
EECCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QSFLPVCPSALPGVLMACCCHPAAHVGGDYYDFFTLEEGAIDMVIADVTGHSVGSSLLMT
HHHHCCCCHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHH
MARSVLNAKVTGSRPPGKLLEVVNDLLHDDLSRAELQISMFYIRLDIPNHTVSYANAGHN
HHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHEEEEEEEEEEEECCCCEEEECCCCCC
HPVLYRSEQADFIELDADGMIMGVKKEVGFEEKTILVAAGDIFILYTDGVTEAESAAGEP
CCEEEECCCCCEEEECCCCEEEEEHHHCCCCCCEEEEEECCEEEEEECCCCHHHHCCCCC
FGTGRLCEAVAAYRDNHPKEIMAGIFRKLTEFTGDGPLADDVAMIIVKIAPSDEAQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MQTKVTENFLNRFRSNRSRLKDEAFLQSYALLSVVFDEAFQLMGLLKPDGTLIKINKAAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHH
RSIKGKESEVIGRPFWDTPWWAHSREEQKRVREGIEAAARGEFIRFETTHAATLDGRVAY
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCEEEE
IDFSLKPVKDERGNVVLVVPEGRDITERRRAEEALREAAIKYRIVADNTFNWEFWLSPEG
EEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCC
RVIYTSPSCERVCGYEADAFTADPGLIWNIVHPDDRQLVDVHRHEVREEKVMGQVEFRIV
EEEEECCCCHHHCCCCCCCEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEE
HRDGDIRWIRHVCQPVFDDNGTYLGIRGSFSDITEQKKAAAALLDNARITRELEIAKEIQ
EECCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QSFLPVCPSALPGVLMACCCHPAAHVGGDYYDFFTLEEGAIDMVIADVTGHSVGSSLLMT
HHHHCCCCHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHH
MARSVLNAKVTGSRPPGKLLEVVNDLLHDDLSRAELQISMFYIRLDIPNHTVSYANAGHN
HHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHEEEEEEEEEEEECCCCEEEECCCCCC
HPVLYRSEQADFIELDADGMIMGVKKEVGFEEKTILVAAGDIFILYTDGVTEAESAAGEP
CCEEEECCCCCEEEECCCCEEEEEHHHCCCCCCEEEEEECCEEEEEECCCCHHHHCCCCC
FGTGRLCEAVAAYRDNHPKEIMAGIFRKLTEFTGDGPLADDVAMIIVKIAPSDEAQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]