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The map label for this gene is fdhD [H]

Identifier: 78223283

GI number: 78223283

Start: 2335777

End: 2336568

Strand: Reverse

Name: fdhD [H]

Synonym: Gmet_2076

Alternate gene names: 78223283

Gene position: 2336568-2335777 (Counterclockwise)

Preceding gene: 78223284

Following gene: 78223282

Centisome position: 58.45

GC content: 61.36

Gene sequence:

>792_bases
ATGAAGAGCATTTACCACTACGACAAAGGTAAACTGGCGGCAACGGAGAAGGAGTTCGTGGGTGAGTTTCCGCTCCTCCT
GAATGTCAACGGTCGCGAGATCGCCACTCTCATCGCCTCGCCCCATGATCTCCGTTTTCTCGTCGCCGGATTCCTGCGGT
TGCAGGGGTTCGTGGAGAAAGTGGAGGACTTCCAGCTTCTCTCGGTCTGCAACGATTTCGGCATTGCGCGGGTTCAGATC
AAGGGCGAACTGCCCGAGAAGTTGAAGCCGGTCCTCACGTCGGGATGCGGCACCGGGATTACCTTCACGATTCCGCAGGC
CACGAAGGGACGGTCCGACTCCCTGGCGGCCAGGCATTTCTCGCCCGCGGCAGTATTCGCCATGATGGAAGAGCTGGCCA
GGAAGGCGGAGGGGTACCGCAGCCACGGCGGAATGCACTCGGCGGCGGTGGGGGACGGTTCCATCGTTCTCTACGCGGAG
GACCTGGGTCGGCACAACACCCTGGACCGGATAGCCGGGGAGGCGCTGTTGAGAGGGATAGACCTGGCAGGCACGATGCT
GGTCACGTCGGGGCGGGTCTCCACGGAGATGGTGGCGAAATGCGTTCTTCTCGGCATTCAGCTCATTGCCTCCCGCACCT
CTCCGACGGATATGGCGGTCAGGATGGCGGATGAAGCGGGTATCACCATGATCGGCTACGTTCGGGGCGGAAGGTTCGAG
CTCTATACCCATCCCGAGCGACTGCGGGTTGACTCGTTGGAGGAGGGATGTGCGTGTGCCACCGGCATATAG

Upstream 100 bases:

>100_bases
CGAGGACAAGCTGACCTTGTCGTTCTTCCGCAACCAGGGGCTGTCTTCAGGCAGGTATGTGGAGTTGGAGACATCATGAG
CGAGGCAGGGGGAATCGACC

Downstream 100 bases:

>100_bases
TCGCTGGAGTGGCCAGGATGGGATCTGCCCGGGATTTATTTCACTCACGGGCAAAATTATCTTGACTTAAAATCGGTATT
CCGGTACTTGTTTACTTGAA

Product: formate dehydrogenase subunit FdhD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKSIYHYDKGKLAATEKEFVGEFPLLLNVNGREIATLIASPHDLRFLVAGFLRLQGFVEKVEDFQLLSVCNDFGIARVQI
KGELPEKLKPVLTSGCGTGITFTIPQATKGRSDSLAARHFSPAAVFAMMEELARKAEGYRSHGGMHSAAVGDGSIVLYAE
DLGRHNTLDRIAGEALLRGIDLAGTMLVTSGRVSTEMVAKCVLLGIQLIASRTSPTDMAVRMADEAGITMIGYVRGGRFE
LYTHPERLRVDSLEEGCACATGI

Sequences:

>Translated_263_residues
MKSIYHYDKGKLAATEKEFVGEFPLLLNVNGREIATLIASPHDLRFLVAGFLRLQGFVEKVEDFQLLSVCNDFGIARVQI
KGELPEKLKPVLTSGCGTGITFTIPQATKGRSDSLAARHFSPAAVFAMMEELARKAEGYRSHGGMHSAAVGDGSIVLYAE
DLGRHNTLDRIAGEALLRGIDLAGTMLVTSGRVSTEMVAKCVLLGIQLIASRTSPTDMAVRMADEAGITMIGYVRGGRFE
LYTHPERLRVDSLEEGCACATGI
>Mature_263_residues
MKSIYHYDKGKLAATEKEFVGEFPLLLNVNGREIATLIASPHDLRFLVAGFLRLQGFVEKVEDFQLLSVCNDFGIARVQI
KGELPEKLKPVLTSGCGTGITFTIPQATKGRSDSLAARHFSPAAVFAMMEELARKAEGYRSHGGMHSAAVGDGSIVLYAE
DLGRHNTLDRIAGEALLRGIDLAGTMLVTSGRVSTEMVAKCVLLGIQLIASRTSPTDMAVRMADEAGITMIGYVRGGRFE
LYTHPERLRVDSLEEGCACATGI

Specific function: Necessary for formate dehydrogenase activity [H]

COG id: COG1526

COG function: function code C; Uncharacterized protein required for formate dehydrogenase activity

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhD family [H]

Homologues:

Organism=Escherichia coli, GI1790329, Length=244, Percent_Identity=26.6393442622951, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003786 [H]

Pfam domain/function: PF02634 FdhD-NarQ [H]

EC number: NA

Molecular weight: Translated: 28406; Mature: 28406

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIYHYDKGKLAATEKEFVGEFPLLLNVNGREIATLIASPHDLRFLVAGFLRLQGFVEK
CCCCEECCCCCEEECHHHHCCCCCEEEECCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHH
VEDFQLLSVCNDFGIARVQIKGELPEKLKPVLTSGCGTGITFTIPQATKGRSDSLAARHF
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCC
SPAAVFAMMEELARKAEGYRSHGGMHSAAVGDGSIVLYAEDLGRHNTLDRIAGEALLRGI
CHHHHHHHHHHHHHHHCCHHHCCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHC
DLAGTMLVTSGRVSTEMVAKCVLLGIQLIASRTSPTDMAVRMADEAGITMIGYVRGGRFE
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCEEEEEEECCEEE
LYTHPERLRVDSLEEGCACATGI
EEECHHHHCCCCHHCCCCCCCCC
>Mature Secondary Structure
MKSIYHYDKGKLAATEKEFVGEFPLLLNVNGREIATLIASPHDLRFLVAGFLRLQGFVEK
CCCCEECCCCCEEECHHHHCCCCCEEEECCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHH
VEDFQLLSVCNDFGIARVQIKGELPEKLKPVLTSGCGTGITFTIPQATKGRSDSLAARHF
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCC
SPAAVFAMMEELARKAEGYRSHGGMHSAAVGDGSIVLYAEDLGRHNTLDRIAGEALLRGI
CHHHHHHHHHHHHHHHCCHHHCCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHC
DLAGTMLVTSGRVSTEMVAKCVLLGIQLIASRTSPTDMAVRMADEAGITMIGYVRGGRFE
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCEEEEEEECCEEE
LYTHPERLRVDSLEEGCACATGI
EEECHHHHCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7860592; 9384377 [H]