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The map label for this gene is mmgC [H]

Identifier: 78223282

GI number: 78223282

Start: 2334414

End: 2335592

Strand: Reverse

Name: mmgC [H]

Synonym: Gmet_2075

Alternate gene names: 78223282

Gene position: 2335592-2334414 (Counterclockwise)

Preceding gene: 78223283

Following gene: 78223281

Centisome position: 58.43

GC content: 61.58

Gene sequence:

>1179_bases
ATGAGTGTTACTACAGAACTGACGGATTACATGGGGTTCCAGGGACTTCTGACCGACGAGGAGAAGCTCGTTCGTGAGAC
TGCCCGCAAGTTCGTCAATGATGAGGTGCTGCCGATCATCGAGGAGCACGCCCTGAACGAGACCTTTCCCAGCCACCTGA
TCCCCAAGATGGGCGAGCTCGGGTTCTACGGTCCGAACCTCCCCGAGAAGTACGGCTGCGCCGGGCTTTCCAACGTGGCC
TATGGTCTGCTGATGTATGAACTGGAGCGGGGCGACTCGGGTCTCAGAAGCTTCGCCTCGGTCCAGGGCTCCCTGGTCAT
GTATCCCATCTACGCCTACGGCAGCGAGGCCCAGAAAGAATACTGGCTCCCCAAGCTGGCCGCCGGTGAGAAGATCGGCT
GCTTCGGCCTGACCGAACCGGATTTCGGCTCCAACCCGGCCGGGATGCGTACCAACGCCGTGCGCGAAGCAAATGGCAAG
TGGCGGATCAACGGCTCCAAGATGTGGATCACCAACGGCAGCGTTGCCGACGTGGCAGTGGTCTGGGCCAGGACCGACGA
CGGCGTCAGGGGCTTCCTGGTTGAGAAGGGTACCCCCGGCTTCTCCGCCCCCAAGATGCACGGCAAGTGGAGCCTGCGGG
CCTCCGTCACCTCCGAGCTCGTCTTCGAGGACGTCATCGTCGATGAAGAAAAGAGCCTCCTCCCCAACGTGAAAGGGCTG
AAGGGTCCCCTGGGATGCCTCACCCAGGCCCGCTATGGTATCGCCTGGGGCGCCCTGGGCGCCGCCGACGCCTGCTACCA
GGCTGCTCTGGAGTACGCCCTCAGCCGGATCCAGTTCGACAAGCCCATCGCTTCCTATCAGCTCCAGCAGCGGAAGCTGG
CCGAGATGGTCACCGAGATCACCAAGGGGCAACTCCTCGTCATGCAGTTGGGCCGCCTCAAGGACCAGGGGAACTACTCT
CCGGCCCAGGTCTCCATGGCCAAGATGAACAACGTCCATGTGGCCATCAACATCTGCCGTACCGCCCGGACCATACTGGG
GGCCAACGGCATCATGAGCGAATACCCGATCATGCGTCACGCCAACAACCTGGAGGCCGTCTATACCTACGAGGGTACCC
ACGACATGCATCTCCTGATCATCGGCGAAAAAGTCACCGGCATTTCGGCCTTCCGGTAA

Upstream 100 bases:

>100_bases
TACTTGTTTACTTGAAGGTGACAGTGTTTTATTTGCCGCATGTGGGAACAGGGGCAAGTCATATACAAACTGCCTGGGAA
AGGCCCGAAAGGAGACAAAA

Downstream 100 bases:

>100_bases
GGAGCGACAGATATGAGTGACGTTTATGTAATCGAATCGCTGCGCACTCCCCTCGGCTCCTTCGGGGGGGAGTTGTCCGA
CGTGGAGGCGCCGCGCCTGG

Product: Acyl-CoA dehydrogenase-like

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSVTTELTDYMGFQGLLTDEEKLVRETARKFVNDEVLPIIEEHALNETFPSHLIPKMGELGFYGPNLPEKYGCAGLSNVA
YGLLMYELERGDSGLRSFASVQGSLVMYPIYAYGSEAQKEYWLPKLAAGEKIGCFGLTEPDFGSNPAGMRTNAVREANGK
WRINGSKMWITNGSVADVAVVWARTDDGVRGFLVEKGTPGFSAPKMHGKWSLRASVTSELVFEDVIVDEEKSLLPNVKGL
KGPLGCLTQARYGIAWGALGAADACYQAALEYALSRIQFDKPIASYQLQQRKLAEMVTEITKGQLLVMQLGRLKDQGNYS
PAQVSMAKMNNVHVAINICRTARTILGANGIMSEYPIMRHANNLEAVYTYEGTHDMHLLIIGEKVTGISAFR

Sequences:

>Translated_392_residues
MSVTTELTDYMGFQGLLTDEEKLVRETARKFVNDEVLPIIEEHALNETFPSHLIPKMGELGFYGPNLPEKYGCAGLSNVA
YGLLMYELERGDSGLRSFASVQGSLVMYPIYAYGSEAQKEYWLPKLAAGEKIGCFGLTEPDFGSNPAGMRTNAVREANGK
WRINGSKMWITNGSVADVAVVWARTDDGVRGFLVEKGTPGFSAPKMHGKWSLRASVTSELVFEDVIVDEEKSLLPNVKGL
KGPLGCLTQARYGIAWGALGAADACYQAALEYALSRIQFDKPIASYQLQQRKLAEMVTEITKGQLLVMQLGRLKDQGNYS
PAQVSMAKMNNVHVAINICRTARTILGANGIMSEYPIMRHANNLEAVYTYEGTHDMHLLIIGEKVTGISAFR
>Mature_391_residues
SVTTELTDYMGFQGLLTDEEKLVRETARKFVNDEVLPIIEEHALNETFPSHLIPKMGELGFYGPNLPEKYGCAGLSNVAY
GLLMYELERGDSGLRSFASVQGSLVMYPIYAYGSEAQKEYWLPKLAAGEKIGCFGLTEPDFGSNPAGMRTNAVREANGKW
RINGSKMWITNGSVADVAVVWARTDDGVRGFLVEKGTPGFSAPKMHGKWSLRASVTSELVFEDVIVDEEKSLLPNVKGLK
GPLGCLTQARYGIAWGALGAADACYQAALEYALSRIQFDKPIASYQLQQRKLAEMVTEITKGQLLVMQLGRLKDQGNYSP
AQVSMAKMNNVHVAINICRTARTILGANGIMSEYPIMRHANNLEAVYTYEGTHDMHLLIIGEKVTGISAFR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=377, Percent_Identity=55.1724137931034, Blast_Score=411, Evalue=1e-115,
Organism=Homo sapiens, GI7669494, Length=365, Percent_Identity=53.6986301369863, Blast_Score=380, Evalue=1e-106,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=35.3099730458221, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=30.4812834224599, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=30.3191489361702, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=31.331592689295, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=31.331592689295, Blast_Score=178, Evalue=6e-45,
Organism=Homo sapiens, GI226958414, Length=356, Percent_Identity=30.6179775280899, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI76496475, Length=395, Percent_Identity=29.620253164557, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4557235, Length=379, Percent_Identity=30.6068601583113, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4501857, Length=388, Percent_Identity=29.8969072164948, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI7656849, Length=396, Percent_Identity=28.5353535353535, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI21361497, Length=340, Percent_Identity=29.7058823529412, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI48976061, Length=339, Percent_Identity=27.7286135693215, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI211971008, Length=339, Percent_Identity=27.7286135693215, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38505218, Length=391, Percent_Identity=23.2736572890026, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786223, Length=377, Percent_Identity=24.6684350132626, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=24.1469816272966, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=392, Percent_Identity=49.4897959183673, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=32.6315789473684, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=32.6370757180157, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=31.5508021390374, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=30.6068601583113, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=393, Percent_Identity=29.2620865139949, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17533517, Length=386, Percent_Identity=28.4974093264249, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=28.7206266318538, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71985184, Length=392, Percent_Identity=27.5510204081633, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=33.695652173913, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=327, Percent_Identity=28.4403669724771, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=30.8695652173913, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=28.3088235294118, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17505929, Length=380, Percent_Identity=25.7894736842105, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=24.5231607629428, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920834, Length=387, Percent_Identity=49.3540051679587, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=33.5135135135135, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=32.0855614973262, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=31.6353887399464, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24660351, Length=373, Percent_Identity=32.9758713136729, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=31.2335958005249, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI281363737, Length=342, Percent_Identity=32.1637426900585, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43113; Mature: 42982

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTTELTDYMGFQGLLTDEEKLVRETARKFVNDEVLPIIEEHALNETFPSHLIPKMGEL
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCC
GFYGPNLPEKYGCAGLSNVAYGLLMYELERGDSGLRSFASVQGSLVMYPIYAYGSEAQKE
CCCCCCCCHHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHCCCCEEEEEEEECCCCHHHH
YWLPKLAAGEKIGCFGLTEPDFGSNPAGMRTNAVREANGKWRINGSKMWITNGSVADVAV
HCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHCCCCCEEEECCCEEEEECCCEEEEEE
VWARTDDGVRGFLVEKGTPGFSAPKMHGKWSLRASVTSELVFEDVIVDEEKSLLPNVKGL
EEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHCCCCCCC
KGPLGCLTQARYGIAWGALGAADACYQAALEYALSRIQFDKPIASYQLQQRKLAEMVTEI
CCHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TKGQLLVMQLGRLKDQGNYSPAQVSMAKMNNVHVAINICRTARTILGANGIMSEYPIMRH
HCCCEEEEHHHCCCCCCCCCHHHEEHHHHCCEEEEEEEHHHHHHHHCCCCCHHCCCHHHC
ANNLEAVYTYEGTHDMHLLIIGEKVTGISAFR
CCCCCEEEEECCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SVTTELTDYMGFQGLLTDEEKLVRETARKFVNDEVLPIIEEHALNETFPSHLIPKMGEL
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCC
GFYGPNLPEKYGCAGLSNVAYGLLMYELERGDSGLRSFASVQGSLVMYPIYAYGSEAQKE
CCCCCCCCHHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHCCCCEEEEEEEECCCCHHHH
YWLPKLAAGEKIGCFGLTEPDFGSNPAGMRTNAVREANGKWRINGSKMWITNGSVADVAV
HCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHCCCCCEEEECCCEEEEECCCEEEEEE
VWARTDDGVRGFLVEKGTPGFSAPKMHGKWSLRASVTSELVFEDVIVDEEKSLLPNVKGL
EEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHCCCCCCC
KGPLGCLTQARYGIAWGALGAADACYQAALEYALSRIQFDKPIASYQLQQRKLAEMVTEI
CCHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TKGQLLVMQLGRLKDQGNYSPAQVSMAKMNNVHVAINICRTARTILGANGIMSEYPIMRH
HCCCEEEEHHHCCCCCCCCCHHHEEHHHHCCEEEEEEEHHHHHHHHCCCCCHHCCCHHHC
ANNLEAVYTYEGTHDMHLLIIGEKVTGISAFR
CCCCCEEEEECCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]