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The map label for this gene is sucC [H]

Identifier: 78223276

GI number: 78223276

Start: 2326778

End: 2327941

Strand: Reverse

Name: sucC [H]

Synonym: Gmet_2069

Alternate gene names: 78223276

Gene position: 2327941-2326778 (Counterclockwise)

Preceding gene: 78223277

Following gene: 78223275

Centisome position: 58.24

GC content: 62.29

Gene sequence:

>1164_bases
ATGAACATCCACGAATATCAGGCAAAAGCAATCCTTCGCAGATTCGGCGTACCCGTCCCTGACGGGCACGTCTGCTATAA
CGGCGCCAGCGCCCGTGAATGGGCCAAGCGTCTCGGTGACGGACCATGGGTGGTCAAGGCCCAGATCCACGCCGGCGGCC
GCGGTAAGGGTGGGGGGGTCAAGCTGGCCCGCACCAGCCAAGAAGTGCAGCTCATCGCCCGTAACATGCTCGGCATGACC
CTGCGCACCCATCAGACCGGCCCCGACGGCAAGTTGGTCACCCGGGTCCTGGTGGAAAACGGCTGCAACATCGACCGGGA
GCTGTACATAAGCCTCCTGGTGGACCGGAGCACCTCCAAGGTGACCGTCATGGCCTCCACCGAGGGGGGCATGGACATCG
AGGAAGTGGCGGCAACGACCCCGGAGAAGATCTTCAAGGAAGCCATCGATCCGCTGGTAGGGCTTAGCCCCTTCCAGTGC
CGTAACCTTGCCTTCAGCCTGGGGCTCACCGGAAAGCTTCTGCCCAAGGCGCAGAAGCTTCTGGAAAATCTCTACGCTAC
CTTCATCGCTTGCGACTGTTCGCTTCTGGAAATAAACCCCCTGGTCGTCACCAAGGAAGGGGACCTTCTGGCCCTGGACG
CCAAATTCGGCTTTGACGACAACGCCATTTTCCGGCACCTGCAGATCTCCGACATGCGCGACTACGACGAGGAGGATCCC
AACGAAGTGGAGGCCTCCCAGCACGACCTCTCCTACGTCTCCCTGAACGGCAACATCGGCTGCCTCGTGAACGGCGCGGG
CCTCGCCATGGCCACCATGGACATCATCAAGTTCTCCGGCGGCGAGCCGGCCAACTTCCTGGACGTGGGGGGCGGGGCCA
CCATCGAGCGGGTCACCGAGGCCTTCAAGATCATCCTCTCCGACAAGAACGTGAAGGGGATCTTCGTCAACATCTTCGGC
GGCATCATGAAGTGCGACGTCATCGCCACGGGCGTCATCGAGGCTGCCCGGCAGGTATCCCTTCAGGTGCCGCTCGTGGT
GCGGCTCGAAGGGACCAACGTGGCCCTCGGCAAGCAGCTTCTGTCCGAGAGTGGGCTCAACATCGTGGCCGCCGACGGCA
TGGCCGACGGAGCACAAAAAATCGTCCAGGCCGTTGCCGCCTGA

Upstream 100 bases:

>100_bases
GAGAAATTTTTGCTTGCCATTAAATCGGTATTGAAGTACCGTATTGCTAAATTGGTGCTGCGATACGGGAATTAAAAAAC
TGACTCGCGGGAGGAATAGG

Downstream 100 bases:

>100_bases
GGAGGGGAGAGAGATGAGCATCCTTATCAATAAAGACACGAAAGTCATCACCCAGGGACTCGGCGCCACCGGCCTCTTTC
ATGCCCAGGGGGCCCGCGAG

Product: succinyl-CoA synthetase (ADP-forming) beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNIHEYQAKAILRRFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGVKLARTSQEVQLIARNMLGMT
LRTHQTGPDGKLVTRVLVENGCNIDRELYISLLVDRSTSKVTVMASTEGGMDIEEVAATTPEKIFKEAIDPLVGLSPFQC
RNLAFSLGLTGKLLPKAQKLLENLYATFIACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAIFRHLQISDMRDYDEEDP
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVALGKQLLSESGLNIVAADGMADGAQKIVQAVAA

Sequences:

>Translated_387_residues
MNIHEYQAKAILRRFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGVKLARTSQEVQLIARNMLGMT
LRTHQTGPDGKLVTRVLVENGCNIDRELYISLLVDRSTSKVTVMASTEGGMDIEEVAATTPEKIFKEAIDPLVGLSPFQC
RNLAFSLGLTGKLLPKAQKLLENLYATFIACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAIFRHLQISDMRDYDEEDP
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVALGKQLLSESGLNIVAADGMADGAQKIVQAVAA
>Mature_387_residues
MNIHEYQAKAILRRFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGVKLARTSQEVQLIARNMLGMT
LRTHQTGPDGKLVTRVLVENGCNIDRELYISLLVDRSTSKVTVMASTEGGMDIEEVAATTPEKIFKEAIDPLVGLSPFQC
RNLAFSLGLTGKLLPKAQKLLENLYATFIACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAIFRHLQISDMRDYDEEDP
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVALGKQLLSESGLNIVAADGMADGAQKIVQAVAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=44.8717948717949, Blast_Score=345, Evalue=4e-95,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.2140992167102, Blast_Score=330, Evalue=1e-90,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=46.7966573816156, Blast_Score=315, Evalue=6e-86,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=56.3636363636364, Blast_Score=439, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=45.6852791878173, Blast_Score=339, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=46.2724935732648, Blast_Score=338, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=46.0559796437659, Blast_Score=359, Evalue=1e-100,
Organism=Drosophila melanogaster, GI161078106, Length=395, Percent_Identity=45.3164556962025, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24645208, Length=395, Percent_Identity=45.3164556962025, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI21356231, Length=393, Percent_Identity=45.8015267175573, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI281361397, Length=396, Percent_Identity=45.4545454545455, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI281361395, Length=396, Percent_Identity=45.4545454545455, Blast_Score=327, Evalue=1e-89,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41439; Mature: 41439

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKAILRRFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGV
CCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KLARTSQEVQLIARNMLGMTLRTHQTGPDGKLVTRVLVENGCNIDRELYISLLVDRSTSK
EEEECHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCE
VTVMASTEGGMDIEEVAATTPEKIFKEAIDPLVGLSPFQCRNLAFSLGLTGKLLPKAQKL
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCHHCCEEEECCCCCCCCHHHHHH
LENLYATFIACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAIFRHLQISDMRDYDEEDP
HHHHHHHHHHCCCEEEEECEEEEECCCCEEEEEECCCCCCCHHEEEEEECCCCCCCCCCC
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTE
CHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHEECCCCCCCEEECCCCCHHHHHHH
AFKIILSDKNVKGIFVNIFGGIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVALGKQL
HHHEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCEEECCEEEEECCCCCHHHHHH
LSESGLNIVAADGMADGAQKIVQAVAA
HHHCCCEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKAILRRFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGV
CCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KLARTSQEVQLIARNMLGMTLRTHQTGPDGKLVTRVLVENGCNIDRELYISLLVDRSTSK
EEEECHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCE
VTVMASTEGGMDIEEVAATTPEKIFKEAIDPLVGLSPFQCRNLAFSLGLTGKLLPKAQKL
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCHHCCEEEECCCCCCCCHHHHHH
LENLYATFIACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAIFRHLQISDMRDYDEEDP
HHHHHHHHHHCCCEEEEECEEEEECCCCEEEEEECCCCCCCHHEEEEEECCCCCCCCCCC
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTE
CHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHEECCCCCCCEEECCCCCHHHHHHH
AFKIILSDKNVKGIFVNIFGGIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVALGKQL
HHHEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCEEECCEEEEECCCCCHHHHHH
LSESGLNIVAADGMADGAQKIVQAVAA
HHHCCCEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA