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The map label for this gene is sucD [H]

Identifier: 78223275

GI number: 78223275

Start: 2325874

End: 2326764

Strand: Reverse

Name: sucD [H]

Synonym: Gmet_2068

Alternate gene names: 78223275

Gene position: 2326764-2325874 (Counterclockwise)

Preceding gene: 78223276

Following gene: 78223274

Centisome position: 58.21

GC content: 64.09

Gene sequence:

>891_bases
ATGAGCATCCTTATCAATAAAGACACGAAAGTCATCACCCAGGGACTCGGCGCCACCGGCCTCTTTCATGCCCAGGGGGC
CCGCGAGTACGGCACCCAGATGGTCGGCGGCGTTACCCCCGGCAAGGGGGGGACGGTCGTCGACGGCTTTCCCGTCTACG
ACACGGTTCGGGATGCGGTGAACCAGACCGGCGCCACCGCCTCGGTAATCTACGTGCCGCCCCCCTTTGCGGCCGACGCC
ATCATGGAGGCGGTCGACGCCGGCATCGAGCTCGCCATCTGCATCACCGAGGGAATCCCAGTCCTCGACATGGTGAAAGT
GAAGCAGTATATGCAGGGGAAAAAGACCCGCCTGGTGGGCCCCAACTGCCCCGGCGTCATCACCCCGGGTGAGTGCAAGA
TCGGCATCATGCCCGGCTACATCCACAAGCCGGGGAAGGTGGGGGTCGTCTCCCGCTCCGGCACCCTTACCTACGAAGCG
GTCTGGCAGCTCACCAACGTGGGTCTCGGCCAGTCCACCTGCGTCGGCATCGGGGGTGACCCGGTGAACGGCACCAACCA
CGTGGACGTGCTCCGGATGTTCGAGGAGGACCCGGACACCGAGGCGGTCATCATGATCGGCGAAATCGGCGGCAATTCCG
AGGAAGAAGGCGCCCGCTTCGTGAAGGAGTACATGACCAAGCCGGTGGCAGCCTACATTGCCGGGATGACCGCCCCTCCG
GGCAAGCGGATGGGGCATGCCGGCGCCATCATCGCCGGCGGCAAGGGGACGGCCACGGAAAAGGTCGCCATCCTTGAGGA
GTGCGGTATCAGCGTTGCCCAAAGCCCCGCCGACATGGCCAAGGCGCTTTTGAAGGTGTACAAGCCCGACGGGCTTAAAA
TAGCGGTTTAA

Upstream 100 bases:

>100_bases
CTTCTGTCCGAGAGTGGGCTCAACATCGTGGCCGCCGACGGCATGGCCGACGGAGCACAAAAAATCGTCCAGGCCGTTGC
CGCCTGAGGAGGGGAGAGAG

Downstream 100 bases:

>100_bases
CCGGCAGATGCATTTGAAACACTGAGCAACTGAGCAAAATCCAAGCATAATTTTATCGATTTCTCTGTTGCTCCGTTGCT
CAGTGTCATACATGCCGGAT

Product: succinyl-CoA synthetase (ADP-forming) subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSILINKDTKVITQGLGATGLFHAQGAREYGTQMVGGVTPGKGGTVVDGFPVYDTVRDAVNQTGATASVIYVPPPFAADA
IMEAVDAGIELAICITEGIPVLDMVKVKQYMQGKKTRLVGPNCPGVITPGECKIGIMPGYIHKPGKVGVVSRSGTLTYEA
VWQLTNVGLGQSTCVGIGGDPVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEYMTKPVAAYIAGMTAPP
GKRMGHAGAIIAGGKGTATEKVAILEECGISVAQSPADMAKALLKVYKPDGLKIAV

Sequences:

>Translated_296_residues
MSILINKDTKVITQGLGATGLFHAQGAREYGTQMVGGVTPGKGGTVVDGFPVYDTVRDAVNQTGATASVIYVPPPFAADA
IMEAVDAGIELAICITEGIPVLDMVKVKQYMQGKKTRLVGPNCPGVITPGECKIGIMPGYIHKPGKVGVVSRSGTLTYEA
VWQLTNVGLGQSTCVGIGGDPVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEYMTKPVAAYIAGMTAPP
GKRMGHAGAIIAGGKGTATEKVAILEECGISVAQSPADMAKALLKVYKPDGLKIAV
>Mature_295_residues
SILINKDTKVITQGLGATGLFHAQGAREYGTQMVGGVTPGKGGTVVDGFPVYDTVRDAVNQTGATASVIYVPPPFAADAI
MEAVDAGIELAICITEGIPVLDMVKVKQYMQGKKTRLVGPNCPGVITPGECKIGIMPGYIHKPGKVGVVSRSGTLTYEAV
WQLTNVGLGQSTCVGIGGDPVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEYMTKPVAAYIAGMTAPPG
KRMGHAGAIIAGGKGTATEKVAILEECGISVAQSPADMAKALLKVYKPDGLKIAV

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=292, Percent_Identity=61.6438356164384, Blast_Score=309, Evalue=2e-84,
Organism=Homo sapiens, GI38569423, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI38569421, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=67.8200692041522, Blast_Score=394, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=58.2191780821918, Blast_Score=320, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=57.3378839590444, Blast_Score=307, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI17557344, Length=257, Percent_Identity=28.7937743190661, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=256, Percent_Identity=28.125, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=51.0135135135135, Blast_Score=283, Evalue=2e-77,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=54.4827586206897, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=58.3617747440273, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI281363477, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363475, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363473, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30705; Mature: 30574

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVITQGLGATGLFHAQGAREYGTQMVGGVTPGKGGTVVDGFPVYDTVRDAV
CEEEEECCHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHH
NQTGATASVIYVPPPFAADAIMEAVDAGIELAICITEGIPVLDMVKVKQYMQGKKTRLVG
HCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEC
PNCPGVITPGECKIGIMPGYIHKPGKVGVVSRSGTLTYEAVWQLTNVGLGQSTCVGIGGD
CCCCCEECCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCCC
PVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEYMTKPVAAYIAGMTAPP
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCC
GKRMGHAGAIIAGGKGTATEKVAILEECGISVAQSPADMAKALLKVYKPDGLKIAV
CCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure 
SILINKDTKVITQGLGATGLFHAQGAREYGTQMVGGVTPGKGGTVVDGFPVYDTVRDAV
EEEEECCHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHH
NQTGATASVIYVPPPFAADAIMEAVDAGIELAICITEGIPVLDMVKVKQYMQGKKTRLVG
HCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEC
PNCPGVITPGECKIGIMPGYIHKPGKVGVVSRSGTLTYEAVWQLTNVGLGQSTCVGIGGD
CCCCCEECCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCCC
PVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEYMTKPVAAYIAGMTAPP
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCC
GKRMGHAGAIIAGGKGTATEKVAILEECGISVAQSPADMAKALLKVYKPDGLKIAV
CCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]