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The map label for this gene is hfq [H]

Identifier: 78223258

GI number: 78223258

Start: 2303281

End: 2303505

Strand: Reverse

Name: hfq [H]

Synonym: Gmet_2051

Alternate gene names: 78223258

Gene position: 2303505-2303281 (Counterclockwise)

Preceding gene: 78223259

Following gene: 78223257

Centisome position: 57.62

GC content: 48.89

Gene sequence:

>225_bases
ATGGCAAAAGCACCGTTCAACATCCAGGATCAATACCTCAACCAGTCGCGGAAAGAGCGGATCAAGGTTGCTGTTCGGCT
CATGTCGGGAGAAAAACTCGAAGGGTACATCAAGTCATTCGACAATTTCTCGGTTCTCATGGAGATCCAGGGCGACATGC
TGATTTACAAGCACGCCATTTCGTCCATCACCTCCGTTGACGGCACCTTTAAACTTCACCAGTAA

Upstream 100 bases:

>100_bases
GGTTTCGCCGGGATTCGGAAATTATCTGGGTTGAATATCCGGGGAAGTTTGATAGTATCTTGAGTACTGTCATGGGATTT
TATCATTAAAGGAGCGGCAT

Downstream 100 bases:

>100_bases
CCCCCTTCCACCGGGGCGTATCCGGCCCTTTCCCCATCGCCGGGGGAGGGCCGGTTGCGTCTTGCCGGCAGTTATTTTTC
CGTGACCACCTATCTCAAAG

Product: host factor Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 74; Mature: 73

Protein sequence:

>74_residues
MAKAPFNIQDQYLNQSRKERIKVAVRLMSGEKLEGYIKSFDNFSVLMEIQGDMLIYKHAISSITSVDGTFKLHQ

Sequences:

>Translated_74_residues
MAKAPFNIQDQYLNQSRKERIKVAVRLMSGEKLEGYIKSFDNFSVLMEIQGDMLIYKHAISSITSVDGTFKLHQ
>Mature_73_residues
AKAPFNIQDQYLNQSRKERIKVAVRLMSGEKLEGYIKSFDNFSVLMEIQGDMLIYKHAISSITSVDGTFKLHQ

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=63, Percent_Identity=44.4444444444444, Blast_Score=59, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 8510; Mature: 8379

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPFNIQDQYLNQSRKERIKVAVRLMSGEKLEGYIKSFDNFSVLMEIQGDMLIYKHAI
CCCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCCHHHHHHH
SSITSVDGTFKLHQ
HHHHCCCCEEEECC
>Mature Secondary Structure 
AKAPFNIQDQYLNQSRKERIKVAVRLMSGEKLEGYIKSFDNFSVLMEIQGDMLIYKHAI
CCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCCHHHHHHH
SSITSVDGTFKLHQ
HHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA