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The map label for this gene is atoS [C]

Identifier: 78223125

GI number: 78223125

Start: 2143212

End: 2145164

Strand: Direct

Name: atoS [C]

Synonym: Gmet_1918

Alternate gene names: 78223125

Gene position: 2143212-2145164 (Clockwise)

Preceding gene: 78223124

Following gene: 78223126

Centisome position: 53.61

GC content: 53.61

Gene sequence:

>1953_bases
ATGACGGTGGCCGTAAACCCTTCTTCTCTTCGAGTCCTCATCATCGATGACTCTCCTTTCGATACCGAACTGGTAATTCG
CGAGCTCAACAGTTGTTTCATCACCCATTTCCGCAGAGTAGACACGGCGGAAGAAATGCTCGATGCCCTTGCAAGCGCGA
CGTGGGATATCGTGATTTCAGACTACGTGATGCCCAGCTTCAGCGGCCTCAATGCCATCGCCCTCCTCAGGAAGGAGGGA
TACACGACGCCGCTCATCGTGGTCTCAGGCAAGATTGAAGATGAGGCCGCCGTAGAAACCATGCGGGCCGGTGCCAACGA
TTACATCCTCAAGGACAATCTTGCGCGACTGGTTCCTGCCATCCGGCGCGAGCTTGAGGAATCAGAGGTCAGGCGGCAGA
AAAAGAAGGTCGAGGATGAGCTGCGCAAGCTATCCCATGCCGTGGAGCAGAGTCCGGTATCCATCATTATCACCGACCAA
AACGGCACCATAGAATACGTGAACCCTAAATTCACCCAGGTTACCGGATATGGCGTCGACGAGGCCGTAGGGCAGACCCC
GCGTATTCTCAAATCGGGCAAAATGCCTGACAGCGAGTATCGGCGCCTCTGGGAAACAATCACCTCCGGCCGCGAATGGC
ATGGCGATATAATCAACAAGAAAAAGAACGGTGATCTGTTCTGGGAACGGGCATCTATTTCGGCCATCAAGGATGCCGAA
GGTGTCATAACCCATTTTGTTGGAGTGAAGGAAGATATCAGCGAACAGCGACGGACAGAACTGGCACACAAACAGGCCAT
GAACCAACTCCGCCAGGCCCAGAAGATGGAAGCCATTGGCCAATTGGCAGGGGGTATCGCCCATGATTTCAACAACCTTC
TTACCGTAATCAACGGTTACAGCACCATGCTGCTCCACGAGATGCCGGTCGACGACCCCTTCCGCTCCGAGGTTAACGAG
ATCCTCAAGGCCGGCGAGCGGGCTGCCGACCTCACCCACCAACTCCTTGCCTTCAGCCGCCGCCAGATGCTTGAGCCCAA
GGTGATCAACATCAACCATCTGGTCAGAAACATGGAGAAGATGCTGAAGCGGCTGATCAGGGAAAACATCGTCATGCATG
CCAGTCTTTACGAGCAACTTGGCGTTGTGAAGGTTGACCCGGGACAGGTGGAGCAGATCATCATGAATCTGCTGGTGAAC
GCCAGAGATGCTCTGGGTAACGGCGGCATCATAACCATCGAAACTGCCGATGTCTATCTGGACAAGACGTTTGTAAACGA
AAACCCAGGGGCGGTTGAAGGTAATTATGTCATGTTGGCGGTTCACGACAACGGAGAGGGGATGACCGAAGAAACCAGGC
GCAAGATCTTCGAACCCTTTTTCACCACCAAGGGGCAGGGAAAAGGGACCGGCCTCGGTCTCGCCACAGTGTACGGCATC
GTCAAACAGAGCGGCGGATACATTCAGGTAGCCAGCGAACTTGGCCAGTGGACATCGTTTCGGGTGTATTTCCCCCGCGT
CGATTCCGAAGCATGGCAGGAAGAAACCGTTACAAGTCACGAAGGGCCAAAGGGTAATGAAACTATCCTGGTTATTGAAG
ATGAAATCGGTGTGCTGAACCTCACCGCCCATACCCTGAAACGGAATGGCTACGAAGTGCTCCAGGCGAGTTCCCCCTCT
GAGGCGAGTAGAATCTTTTCCACCAACCACCACCGGATTGATCTTGTCCTCTCCGATGTTATCATGCCCGAAAAAAATGG
CCCAGCGCTGGTGCGGGAATTCAGGGAGAAACTCCCTGATCTAAAAATCCTATTCATGTCGGGTTACACGGATGATACGA
TATCGTCCCCACAAATTATCGATGAGCACGCAGCCTTTATCAACAAGCCTTTCACGCCCGATGTGCTGGTCGAACGTGTG
CGGGATGTCCTTGAGGGCCGGCTGAATATGTAA

Upstream 100 bases:

>100_bases
GGCAAATTTTTATCGTAGAGTTAAACTTTCTGCATAAAACGCCGAAAAGATACAAGGGGAGCGACGTAATGAAATTTCTC
CGGATCAGACGGAGCATGAA

Downstream 100 bases:

>100_bases
ACGCGAGAGGAGCTCCTGTGCTACCCACCATCTTGACTGTCGACGACGAGGAAATGATCAGAGACCTTATGGTTACGGCC
CTTTCCCGTGAGGGATACCG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MTVAVNPSSLRVLIIDDSPFDTELVIRELNSCFITHFRRVDTAEEMLDALASATWDIVISDYVMPSFSGLNAIALLRKEG
YTTPLIVVSGKIEDEAAVETMRAGANDYILKDNLARLVPAIRRELEESEVRRQKKKVEDELRKLSHAVEQSPVSIIITDQ
NGTIEYVNPKFTQVTGYGVDEAVGQTPRILKSGKMPDSEYRRLWETITSGREWHGDIINKKKNGDLFWERASISAIKDAE
GVITHFVGVKEDISEQRRTELAHKQAMNQLRQAQKMEAIGQLAGGIAHDFNNLLTVINGYSTMLLHEMPVDDPFRSEVNE
ILKAGERAADLTHQLLAFSRRQMLEPKVININHLVRNMEKMLKRLIRENIVMHASLYEQLGVVKVDPGQVEQIIMNLLVN
ARDALGNGGIITIETADVYLDKTFVNENPGAVEGNYVMLAVHDNGEGMTEETRRKIFEPFFTTKGQGKGTGLGLATVYGI
VKQSGGYIQVASELGQWTSFRVYFPRVDSEAWQEETVTSHEGPKGNETILVIEDEIGVLNLTAHTLKRNGYEVLQASSPS
EASRIFSTNHHRIDLVLSDVIMPEKNGPALVREFREKLPDLKILFMSGYTDDTISSPQIIDEHAAFINKPFTPDVLVERV
RDVLEGRLNM

Sequences:

>Translated_650_residues
MTVAVNPSSLRVLIIDDSPFDTELVIRELNSCFITHFRRVDTAEEMLDALASATWDIVISDYVMPSFSGLNAIALLRKEG
YTTPLIVVSGKIEDEAAVETMRAGANDYILKDNLARLVPAIRRELEESEVRRQKKKVEDELRKLSHAVEQSPVSIIITDQ
NGTIEYVNPKFTQVTGYGVDEAVGQTPRILKSGKMPDSEYRRLWETITSGREWHGDIINKKKNGDLFWERASISAIKDAE
GVITHFVGVKEDISEQRRTELAHKQAMNQLRQAQKMEAIGQLAGGIAHDFNNLLTVINGYSTMLLHEMPVDDPFRSEVNE
ILKAGERAADLTHQLLAFSRRQMLEPKVININHLVRNMEKMLKRLIRENIVMHASLYEQLGVVKVDPGQVEQIIMNLLVN
ARDALGNGGIITIETADVYLDKTFVNENPGAVEGNYVMLAVHDNGEGMTEETRRKIFEPFFTTKGQGKGTGLGLATVYGI
VKQSGGYIQVASELGQWTSFRVYFPRVDSEAWQEETVTSHEGPKGNETILVIEDEIGVLNLTAHTLKRNGYEVLQASSPS
EASRIFSTNHHRIDLVLSDVIMPEKNGPALVREFREKLPDLKILFMSGYTDDTISSPQIIDEHAAFINKPFTPDVLVERV
RDVLEGRLNM
>Mature_649_residues
TVAVNPSSLRVLIIDDSPFDTELVIRELNSCFITHFRRVDTAEEMLDALASATWDIVISDYVMPSFSGLNAIALLRKEGY
TTPLIVVSGKIEDEAAVETMRAGANDYILKDNLARLVPAIRRELEESEVRRQKKKVEDELRKLSHAVEQSPVSIIITDQN
GTIEYVNPKFTQVTGYGVDEAVGQTPRILKSGKMPDSEYRRLWETITSGREWHGDIINKKKNGDLFWERASISAIKDAEG
VITHFVGVKEDISEQRRTELAHKQAMNQLRQAQKMEAIGQLAGGIAHDFNNLLTVINGYSTMLLHEMPVDDPFRSEVNEI
LKAGERAADLTHQLLAFSRRQMLEPKVININHLVRNMEKMLKRLIRENIVMHASLYEQLGVVKVDPGQVEQIIMNLLVNA
RDALGNGGIITIETADVYLDKTFVNENPGAVEGNYVMLAVHDNGEGMTEETRRKIFEPFFTTKGQGKGTGLGLATVYGIV
KQSGGYIQVASELGQWTSFRVYFPRVDSEAWQEETVTSHEGPKGNETILVIEDEIGVLNLTAHTLKRNGYEVLQASSPSE
ASRIFSTNHHRIDLVLSDVIMPEKNGPALVREFREKLPDLKILFMSGYTDDTISSPQIIDEHAAFINKPFTPDVLVERVR
DVLEGRLNM

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=439, Percent_Identity=25.7403189066059, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=27.6, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790300, Length=359, Percent_Identity=25.6267409470752, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788713, Length=303, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=413, Percent_Identity=22.2760290556901, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI48994928, Length=270, Percent_Identity=28.1481481481481, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1789453, Length=94, Percent_Identity=31.9148936170213, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=27.6422764227642, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790863, Length=124, Percent_Identity=33.0645161290323, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72924; Mature: 72793

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50162 RECA_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAVNPSSLRVLIIDDSPFDTELVIRELNSCFITHFRRVDTAEEMLDALASATWDIVIS
CEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHEEEE
DYVMPSFSGLNAIALLRKEGYTTPLIVVSGKIEDEAAVETMRAGANDYILKDNLARLVPA
CHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEHHHHHHHHHH
IRRELEESEVRRQKKKVEDELRKLSHAVEQSPVSIIITDQNGTIEYVNPKFTQVTGYGVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEEECCCCH
EAVGQTPRILKSGKMPDSEYRRLWETITSGREWHGDIINKKKNGDLFWERASISAIKDAE
HHCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEECCHHHHHHHH
GVITHFVGVKEDISEQRRTELAHKQAMNQLRQAQKMEAIGQLAGGIAHDFNNLLTVINGY
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
STMLLHEMPVDDPFRSEVNEILKAGERAADLTHQLLAFSRRQMLEPKVININHLVRNMEK
HHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHH
MLKRLIRENIVMHASLYEQLGVVKVDPGQVEQIIMNLLVNARDALGNGGIITIETADVYL
HHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEE
DKTFVNENPGAVEGNYVMLAVHDNGEGMTEETRRKIFEPFFTTKGQGKGTGLGLATVYGI
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VKQSGGYIQVASELGQWTSFRVYFPRVDSEAWQEETVTSHEGPKGNETILVIEDEIGVLN
HHCCCCEEEEHHHCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCEEE
LTAHTLKRNGYEVLQASSPSEASRIFSTNHHRIDLVLSDVIMPEKNGPALVREFREKLPD
EHHHHHHCCCHHEEECCCCHHHHHHHCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHCCC
LKILFMSGYTDDTISSPQIIDEHAAFINKPFTPDVLVERVRDVLEGRLNM
EEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVAVNPSSLRVLIIDDSPFDTELVIRELNSCFITHFRRVDTAEEMLDALASATWDIVIS
EEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHEEEE
DYVMPSFSGLNAIALLRKEGYTTPLIVVSGKIEDEAAVETMRAGANDYILKDNLARLVPA
CHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEHHHHHHHHHH
IRRELEESEVRRQKKKVEDELRKLSHAVEQSPVSIIITDQNGTIEYVNPKFTQVTGYGVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEEECCCCH
EAVGQTPRILKSGKMPDSEYRRLWETITSGREWHGDIINKKKNGDLFWERASISAIKDAE
HHCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEECCHHHHHHHH
GVITHFVGVKEDISEQRRTELAHKQAMNQLRQAQKMEAIGQLAGGIAHDFNNLLTVINGY
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
STMLLHEMPVDDPFRSEVNEILKAGERAADLTHQLLAFSRRQMLEPKVININHLVRNMEK
HHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHH
MLKRLIRENIVMHASLYEQLGVVKVDPGQVEQIIMNLLVNARDALGNGGIITIETADVYL
HHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEE
DKTFVNENPGAVEGNYVMLAVHDNGEGMTEETRRKIFEPFFTTKGQGKGTGLGLATVYGI
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VKQSGGYIQVASELGQWTSFRVYFPRVDSEAWQEETVTSHEGPKGNETILVIEDEIGVLN
HHCCCCEEEEHHHCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCEEE
LTAHTLKRNGYEVLQASSPSEASRIFSTNHHRIDLVLSDVIMPEKNGPALVREFREKLPD
EHHHHHHCCCHHEEECCCCHHHHHHHCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHCCC
LKILFMSGYTDDTISSPQIIDEHAAFINKPFTPDVLVERVRDVLEGRLNM
EEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA