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The map label for this gene is yegE [H]

Identifier: 78223124

GI number: 78223124

Start: 2141788

End: 2143047

Strand: Direct

Name: yegE [H]

Synonym: Gmet_1917

Alternate gene names: 78223124

Gene position: 2141788-2143047 (Clockwise)

Preceding gene: 78223116

Following gene: 78223125

Centisome position: 53.58

GC content: 54.21

Gene sequence:

>1260_bases
TTGAATCCCCCTCTACGTGTACTCATAATCGAAGACTCTGAAGACGATTGTTTTTTCCTCATCAGGGCACTCAAAAAAGA
GTACGAAATCACCCACGAACGGGTTGACACGGAAGATGCTCTTCGCAAGGCGCTCATCGGCGAGAAGTGGGATATTGTTC
TGTCCGACTACTTCATGCCCCAGTTCGATGCGTTGGCTGCGCTATTGATTCTCCAGGAGATGAATCTGGATCTCCCGTTT
ATAATCGTTTCCGGCAGGATAGGCGAGATAGAAGCGGTCAAGGCGATGAAGGCCGGCGCCCACGACTATATCATGAAGGG
AGATTTTACCCGTCTCATGCCTGCCATACGCAGGGAACTGCGTGAGGCCGTCATACGCGAAGAACGTCGCCGGGCTGAGA
GAGATCTGCGGGAACAGCTCCACTTCAGACAGGTGCTCATCGACTCCATCCCCGCCCCCATTTTTTTCAAGAACACTAAC
GGGGTGTTTCTGGGGTGCAACAAGGCCTTCGAGTCGTTCTCAGGCCTTGTCCAGAACGAGGTTATCGGCAAAACCATGGC
TGATCTTGCCTCGAACAGCATTTCCGAACGGTTCGTTGAAGCCGACAAAGAGTTGTTTCAGCATGGAGGCACTCAAATCT
ATGAAAGCTCCATTTCCTTTGCCGACGGAGCTCTCCACGACGTCATCTTCTATAAAGCCACCTTCAACAACATCGACAAC
ACCCTCGGCGGGCTCGTCGGTACGATCCTCGACATTACCGAGCGCAAACAGACAGAGGAAAAGCTCCGCTACATGAGCAC
CCATGATCCGCTTACCGGCCTCTACAACCGGGCCTATTTCCAAGAAGAACTCGAACGTCTCGAGCAGGGGCGTCAGTTTC
CGGTAAGCATCGTGGTCAGCGATATCGACAAGCTCAAGTACGTCAACGACAGCCTGGGCCATGCAGCAGGGGATGATCTG
ATAACCCGGGCCGCCCTGATACTCAAAGGGGCTTTCCGCGCTGAGGACGTTGTGGCGAGAATCGGTGGCGACGAGTTCGC
TGTTCTTCTCCCAACTGCCGACGCGGTGGTCGTGGAAGAGGCTCTCACACGGGTGATGTCGAAAATCGAGGCGAGCAATA
CCCCCGACGTCTCCTTCGCGCTCAGCATGTCTTTTGGTGCGGCTACCGCCTCGAAGGGGGAGCGGCTGGAGGAAACCCAG
AAGCTTGCCGACAAAAGAATGTATCAGCACAAGTTCAAGAAGAACCACACGGCTGCCTAA

Upstream 100 bases:

>100_bases
TGGTTCCTGCAACAAACATCTGACTCACGAAAGGATGCAATCTCGTGATCGTTCACAGGGAATTCCGAAACATAATAATT
CCCTACTGTGGAGAGCCCAA

Downstream 100 bases:

>100_bases
AACCTTCCTCCGTCCCCCCTGTCGGTAACCGTTCAATCCCTCAAAAATACAATGCCGGGGCACCGGCAAATTTTTATCGT
AGAGTTAAACTTTCTGCATA

Product: response regulator receiver /GGDEF/PAS/PAC domain-containing protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNPPLRVLIIEDSEDDCFFLIRALKKEYEITHERVDTEDALRKALIGEKWDIVLSDYFMPQFDALAALLILQEMNLDLPF
IIVSGRIGEIEAVKAMKAGAHDYIMKGDFTRLMPAIRRELREAVIREERRRAERDLREQLHFRQVLIDSIPAPIFFKNTN
GVFLGCNKAFESFSGLVQNEVIGKTMADLASNSISERFVEADKELFQHGGTQIYESSISFADGALHDVIFYKATFNNIDN
TLGGLVGTILDITERKQTEEKLRYMSTHDPLTGLYNRAYFQEELERLEQGRQFPVSIVVSDIDKLKYVNDSLGHAAGDDL
ITRAALILKGAFRAEDVVARIGGDEFAVLLPTADAVVVEEALTRVMSKIEASNTPDVSFALSMSFGAATASKGERLEETQ
KLADKRMYQHKFKKNHTAA

Sequences:

>Translated_419_residues
MNPPLRVLIIEDSEDDCFFLIRALKKEYEITHERVDTEDALRKALIGEKWDIVLSDYFMPQFDALAALLILQEMNLDLPF
IIVSGRIGEIEAVKAMKAGAHDYIMKGDFTRLMPAIRRELREAVIREERRRAERDLREQLHFRQVLIDSIPAPIFFKNTN
GVFLGCNKAFESFSGLVQNEVIGKTMADLASNSISERFVEADKELFQHGGTQIYESSISFADGALHDVIFYKATFNNIDN
TLGGLVGTILDITERKQTEEKLRYMSTHDPLTGLYNRAYFQEELERLEQGRQFPVSIVVSDIDKLKYVNDSLGHAAGDDL
ITRAALILKGAFRAEDVVARIGGDEFAVLLPTADAVVVEEALTRVMSKIEASNTPDVSFALSMSFGAATASKGERLEETQ
KLADKRMYQHKFKKNHTAA
>Mature_419_residues
MNPPLRVLIIEDSEDDCFFLIRALKKEYEITHERVDTEDALRKALIGEKWDIVLSDYFMPQFDALAALLILQEMNLDLPF
IIVSGRIGEIEAVKAMKAGAHDYIMKGDFTRLMPAIRRELREAVIREERRRAERDLREQLHFRQVLIDSIPAPIFFKNTN
GVFLGCNKAFESFSGLVQNEVIGKTMADLASNSISERFVEADKELFQHGGTQIYESSISFADGALHDVIFYKATFNNIDN
TLGGLVGTILDITERKQTEEKLRYMSTHDPLTGLYNRAYFQEELERLEQGRQFPVSIVVSDIDKLKYVNDSLGHAAGDDL
ITRAALILKGAFRAEDVVARIGGDEFAVLLPTADAVVVEEALTRVMSKIEASNTPDVSFALSMSFGAATASKGERLEETQ
KLADKRMYQHKFKKNHTAA

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=270, Percent_Identity=29.2592592592593, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082007, Length=160, Percent_Identity=36.25, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081881, Length=284, Percent_Identity=26.4084507042254, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787541, Length=296, Percent_Identity=26.0135135135135, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787262, Length=149, Percent_Identity=32.8859060402685, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=31.5151515151515, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87081974, Length=151, Percent_Identity=33.7748344370861, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693134, Length=180, Percent_Identity=31.6666666666667, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=156, Percent_Identity=32.6923076923077, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=140, Percent_Identity=27.8571428571429, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787056, Length=144, Percent_Identity=31.25, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788085, Length=154, Percent_Identity=29.8701298701299, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 47224; Mature: 47224

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPLRVLIIEDSEDDCFFLIRALKKEYEITHERVDTEDALRKALIGEKWDIVLSDYFMP
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEHHHCCC
QFDALAALLILQEMNLDLPFIIVSGRIGEIEAVKAMKAGAHDYIMKGDFTRLMPAIRREL
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHH
REAVIREERRRAERDLREQLHFRQVLIDSIPAPIFFKNTNGVFLGCNKAFESFSGLVQNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECHHHHHHHHHHHHHH
VIGKTMADLASNSISERFVEADKELFQHGGTQIYESSISFADGALHDVIFYKATFNNIDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCCHHHHHHHHHHHHHHHHH
TLGGLVGTILDITERKQTEEKLRYMSTHDPLTGLYNRAYFQEELERLEQGRQFPVSIVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
DIDKLKYVNDSLGHAAGDDLITRAALILKGAFRAEDVVARIGGDEFAVLLPTADAVVVEE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
ALTRVMSKIEASNTPDVSFALSMSFGAATASKGERLEETQKLADKRMYQHKFKKNHTAA
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNPPLRVLIIEDSEDDCFFLIRALKKEYEITHERVDTEDALRKALIGEKWDIVLSDYFMP
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEHHHCCC
QFDALAALLILQEMNLDLPFIIVSGRIGEIEAVKAMKAGAHDYIMKGDFTRLMPAIRREL
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHH
REAVIREERRRAERDLREQLHFRQVLIDSIPAPIFFKNTNGVFLGCNKAFESFSGLVQNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECHHHHHHHHHHHHHH
VIGKTMADLASNSISERFVEADKELFQHGGTQIYESSISFADGALHDVIFYKATFNNIDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCCHHHHHHHHHHHHHHHHH
TLGGLVGTILDITERKQTEEKLRYMSTHDPLTGLYNRAYFQEELERLEQGRQFPVSIVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
DIDKLKYVNDSLGHAAGDDLITRAALILKGAFRAEDVVARIGGDEFAVLLPTADAVVVEE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
ALTRVMSKIEASNTPDVSFALSMSFGAATASKGERLEETQKLADKRMYQHKFKKNHTAA
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]