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The map label for this gene is aroB [H]

Identifier: 78223035

GI number: 78223035

Start: 2042314

End: 2043228

Strand: Reverse

Name: aroB [H]

Synonym: Gmet_1828

Alternate gene names: 78223035

Gene position: 2043228-2042314 (Counterclockwise)

Preceding gene: 78223036

Following gene: 78223034

Centisome position: 51.11

GC content: 59.89

Gene sequence:

>915_bases
ATGCATGACGTACTGGCATCCATTGACCTTGGCACCAACACGGCTCGGCTCCTCATCGGGAAAGTGGAGGGAGGAGCTGT
GGCCCCGATTCTCGTCAAGCGCCGCATAACACGACTTGGCGGGGGATTCACTCGGGAGGCCGGGATTTCTCCCGAGGCGT
GGCAACGCTCCCTCGATGCATTGATTGATTTTGCCGCAGAGATGAAACGGGGAGGCGTTACGCGGCTGAGGGCCGTTGCC
ACGAGTGCGGTCCGCGATGCAGTCAATGGCGCCGCGTTCTGCAGCGAGGTGACTGAGCGGACCGGCATCCGGTTGGAGGT
GATCGACGGTGAGGAGGAGGGGCTGTTGACATTGGCTGGGGTGATTTCGGGATTGAACCGCAAGGAAGGGGACTTCTTCG
TTTTTGATGTGGGAGGAGGGAGCACCGAGTACACCCTGGCCGAATCACGCAGGCCGCTCCATACCGAGAGTCTCCCCCTC
GGAGTGGTCAGGCTCACCGAAGGGAAACCCGATGTCCCGGCCATGGAAGAAAAAATCGGCAGGGAACTGGCCGGGCTCGG
GAAAAGTCTTGAAGGGGAGGGCCTCCGGGGACGCCTCGATGGGGCAACGCTCGTCGGTACTGCCGGCACGGCAACAACCC
TGGCAGCCATCAGCCTCCAGATGACCGACTATGACTACCGCCGCGTGAACAATCATGTCATCACCCGTGATGAGATCGGG
AGGATCTTTACGATGCTCCTTCCCCTATCTTCAGAAGAACGCCTTACGGTGCCCGGGCTCGAAAAGGGACGTGAAGACCT
CATAATCGCGGGCATCCTCATCACCCTCAAGACTATGGATGTCTTCGGTTTTGACCGGATGACCGTGAGCGACTTCGGGC
TTTTGGAGGGAGTGTTGCTTGGCCTCGGCGTTTGA

Upstream 100 bases:

>100_bases
CAGTGCGGGCCGGGATCATCTACGCTGACATGATTTCGGCGTTTGCCAAAGTAGCCGATTCCTGTCTCACCATCATAGAA
ACCAGGAGGGAATTCACCTG

Downstream 100 bases:

>100_bases
TAGTATCAAACCCCTACAAAAGCTCTAAAAACCCAAAGGAGTTGACTTACAATCCGCTTATTTTGTATAGTCCTTGAACC
GTTAAGGGGGGCTTTCCCCT

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MHDVLASIDLGTNTARLLIGKVEGGAVAPILVKRRITRLGGGFTREAGISPEAWQRSLDALIDFAAEMKRGGVTRLRAVA
TSAVRDAVNGAAFCSEVTERTGIRLEVIDGEEEGLLTLAGVISGLNRKEGDFFVFDVGGGSTEYTLAESRRPLHTESLPL
GVVRLTEGKPDVPAMEEKIGRELAGLGKSLEGEGLRGRLDGATLVGTAGTATTLAAISLQMTDYDYRRVNNHVITRDEIG
RIFTMLLPLSSEERLTVPGLEKGREDLIIAGILITLKTMDVFGFDRMTVSDFGLLEGVLLGLGV

Sequences:

>Translated_304_residues
MHDVLASIDLGTNTARLLIGKVEGGAVAPILVKRRITRLGGGFTREAGISPEAWQRSLDALIDFAAEMKRGGVTRLRAVA
TSAVRDAVNGAAFCSEVTERTGIRLEVIDGEEEGLLTLAGVISGLNRKEGDFFVFDVGGGSTEYTLAESRRPLHTESLPL
GVVRLTEGKPDVPAMEEKIGRELAGLGKSLEGEGLRGRLDGATLVGTAGTATTLAAISLQMTDYDYRRVNNHVITRDEIG
RIFTMLLPLSSEERLTVPGLEKGREDLIIAGILITLKTMDVFGFDRMTVSDFGLLEGVLLGLGV
>Mature_304_residues
MHDVLASIDLGTNTARLLIGKVEGGAVAPILVKRRITRLGGGFTREAGISPEAWQRSLDALIDFAAEMKRGGVTRLRAVA
TSAVRDAVNGAAFCSEVTERTGIRLEVIDGEEEGLLTLAGVISGLNRKEGDFFVFDVGGGSTEYTLAESRRPLHTESLPL
GVVRLTEGKPDVPAMEEKIGRELAGLGKSLEGEGLRGRLDGATLVGTAGTATTLAAISLQMTDYDYRRVNNHVITRDEIG
RIFTMLLPLSSEERLTVPGLEKGREDLIIAGILITLKTMDVFGFDRMTVSDFGLLEGVLLGLGV

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=297, Percent_Identity=26.5993265993266, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI48994966, Length=310, Percent_Identity=26.4516129032258, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 32479; Mature: 32479

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDVLASIDLGTNTARLLIGKVEGGAVAPILVKRRITRLGGGFTREAGISPEAWQRSLDA
CCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LIDFAAEMKRGGVTRLRAVATSAVRDAVNGAAFCSEVTERTGIRLEVIDGEEEGLLTLAG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
VISGLNRKEGDFFVFDVGGGSTEYTLAESRRPLHTESLPLGVVRLTEGKPDVPAMEEKIG
HHHCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHH
RELAGLGKSLEGEGLRGRLDGATLVGTAGTATTLAAISLQMTDYDYRRVNNHVITRDEIG
HHHHHCCCCCCCCCCEEECCCEEEEECCCCHHEEEEEEEEECCCHHHHHCCCEECHHHHH
RIFTMLLPLSSEERLTVPGLEKGREDLIIAGILITLKTMDVFGFDRMTVSDFGLLEGVLL
HHHHHHHCCCCCCEEECCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GLGV
HCCC
>Mature Secondary Structure
MHDVLASIDLGTNTARLLIGKVEGGAVAPILVKRRITRLGGGFTREAGISPEAWQRSLDA
CCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LIDFAAEMKRGGVTRLRAVATSAVRDAVNGAAFCSEVTERTGIRLEVIDGEEEGLLTLAG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
VISGLNRKEGDFFVFDVGGGSTEYTLAESRRPLHTESLPLGVVRLTEGKPDVPAMEEKIG
HHHCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHH
RELAGLGKSLEGEGLRGRLDGATLVGTAGTATTLAAISLQMTDYDYRRVNNHVITRDEIG
HHHHHCCCCCCCCCCEEECCCEEEEECCCCHHEEEEEEEEECCCHHHHHCCCEECHHHHH
RIFTMLLPLSSEERLTVPGLEKGREDLIIAGILITLKTMDVFGFDRMTVSDFGLLEGVLL
HHHHHHHCCCCCCEEECCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GLGV
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]