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The map label for this gene is glpD2 [H]

Identifier: 78222886

GI number: 78222886

Start: 1884413

End: 1885963

Strand: Direct

Name: glpD2 [H]

Synonym: Gmet_1677

Alternate gene names: 78222886

Gene position: 1884413-1885963 (Clockwise)

Preceding gene: 78222885

Following gene: 78222892

Centisome position: 47.14

GC content: 68.6

Gene sequence:

>1551_bases
ATGACCCGTACGAGGCTCTTGCAACAGCTTGAAGAGGAGAAGTGCTGGGATCTCCTCGTTATCGGCGGGGGCGCCACCGG
GCTCGGCGTGGCCGTTGAGGGGGCGAGCCGGGGCTACCGGACGCTCCTCCTGGAGCGTGACGACTTCGGCAGCGGCACCT
CCAGCCGGAGCACCAAGCTCATCCACGGCGGGGTCCGGTACCTGCAGCAGGGGAATCTCTCCCTGGTACTGGAGGCCCTC
CACGAGCGGGGAATCCTGATCCGCAACGCCCCGCACCTGGTGCATAACCTCTCCTTCGTGGTCCCGCTCTATGACTGGTG
GGAAGGTCCCTTCTACGGCATCGGACTGAAGCTCTACGACATGTTGGCGGGAAAGCTGGGACTCGGCCCGTCGCAGATAC
TCTCCCGGGAGGAGACCCTGCGCCGCATCCCCACCGTGGAGCCGGCAGGGTTGCGGGGCGGGGTGATCTACCACGACGGC
CAGTTCGACGATGCCCGGCTTGCCGTGGCCCTGGCCCGCACCTGCGCGGACCTGGGGGGAGTTCCCCTGAACCGCATGGA
GGTGGCAGGCCTCCTCAAGGGGGATGGCCTGGTCCGCGGCGTAGCGGCCCGGGACCGGGAGAGCGGCCGCGAATACGAGA
TCGAGGCGCGGGTGGTGGTGAATGCCACCGGGCCCTCCTGCGACGCCATCCGCCAGCTGGACGACCCCGGCGCGCAGCCG
GTCATTGCTCCGAGCCAGGGGGTGCATCTGGTCCTGCCCCGGGAATTCCTCCCCGGCGACAGCGCCATCATGGTCCCCCA
CACCGACGACGGGAGGGTGCTCTTCGCCGTCCCCTGGCACGAACGGGTGATCGTCGGCACCACCGACACGCCGGTGGAGC
GGGTCACGGCCGAACCCCGTCCCCTGGCGGCTGAAGTGGGGTTCCTCCTGGAACATGCGGCCCGGTATCTCTCCCGGGAT
CCCGCCACGTCCGACATCCTCAGTGTCTTCGCCGGGCTCCGCCCCCTGGTGCGGGGTGAAGCAGTCAATACAGCGGCCCT
TTCCCGTGATCACACCATTATGGTTTCGACCGCCGGTCTGGTCACCATCACCGGCGGCAAGTGGACCACCTACCGCAGGA
TGGCCGAGGATACGGTAAACAGCGCTGTCAGGATGGCGGGGCTGGCAGAGAGACCGTCGCGCACGGCCGACCTCCCCATC
CACGGGTGGCTGGCCAAGGGGGGTGTTGACGGGGAGTGGGCGATGTATGGCGCCGAAGCCGCTGCCCTGGAAGAGCTGTG
CGCCGTGCAACCGGCCCTGCGCCGGCAACTCCATCCCCGGCTCCCGTACCGGCTGGCCGAGGTGGTCTGGGGGGTGCGGT
ACGAATGGGCGCGGAGTGTTGAGGATGTGTTGAGCCGCCGTACCCGGGCACTCATTCTCGATGCCCGTGCCGCCATGGAG
GCGGCCCCGGAGGTTGCCGCCCTGATGGCGACGGAACTGGGGCGCGATGAGGCCTGGCAGGCGGCAGAGGTTGCGGCTTT
TCGCGCCCTGGCTGAGGGGTATCTGCCTTAG

Upstream 100 bases:

>100_bases
TGGACCGGATCTTCGAGCCGGCCATGGGCCGCGAGCAGGCGGCAGAGCTACGGGGAAGGTGGGGGCGGGCCGTGGAGCGG
GCCCGGGGGTGGGCGGCGCC

Downstream 100 bases:

>100_bases
TTCATGGTTGCTTCATGAAAGTCGTATTCTGTTCAGTCAAGGGGAGTTGGTTGGAGGGAGGGCGATACGTTTAGTCCGAA
GCTTCAACGCCCCTTCGGCG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MTRTRLLQQLEEEKCWDLLVIGGGATGLGVAVEGASRGYRTLLLERDDFGSGTSSRSTKLIHGGVRYLQQGNLSLVLEAL
HERGILIRNAPHLVHNLSFVVPLYDWWEGPFYGIGLKLYDMLAGKLGLGPSQILSREETLRRIPTVEPAGLRGGVIYHDG
QFDDARLAVALARTCADLGGVPLNRMEVAGLLKGDGLVRGVAARDRESGREYEIEARVVVNATGPSCDAIRQLDDPGAQP
VIAPSQGVHLVLPREFLPGDSAIMVPHTDDGRVLFAVPWHERVIVGTTDTPVERVTAEPRPLAAEVGFLLEHAARYLSRD
PATSDILSVFAGLRPLVRGEAVNTAALSRDHTIMVSTAGLVTITGGKWTTYRRMAEDTVNSAVRMAGLAERPSRTADLPI
HGWLAKGGVDGEWAMYGAEAAALEELCAVQPALRRQLHPRLPYRLAEVVWGVRYEWARSVEDVLSRRTRALILDARAAME
AAPEVAALMATELGRDEAWQAAEVAAFRALAEGYLP

Sequences:

>Translated_516_residues
MTRTRLLQQLEEEKCWDLLVIGGGATGLGVAVEGASRGYRTLLLERDDFGSGTSSRSTKLIHGGVRYLQQGNLSLVLEAL
HERGILIRNAPHLVHNLSFVVPLYDWWEGPFYGIGLKLYDMLAGKLGLGPSQILSREETLRRIPTVEPAGLRGGVIYHDG
QFDDARLAVALARTCADLGGVPLNRMEVAGLLKGDGLVRGVAARDRESGREYEIEARVVVNATGPSCDAIRQLDDPGAQP
VIAPSQGVHLVLPREFLPGDSAIMVPHTDDGRVLFAVPWHERVIVGTTDTPVERVTAEPRPLAAEVGFLLEHAARYLSRD
PATSDILSVFAGLRPLVRGEAVNTAALSRDHTIMVSTAGLVTITGGKWTTYRRMAEDTVNSAVRMAGLAERPSRTADLPI
HGWLAKGGVDGEWAMYGAEAAALEELCAVQPALRRQLHPRLPYRLAEVVWGVRYEWARSVEDVLSRRTRALILDARAAME
AAPEVAALMATELGRDEAWQAAEVAAFRALAEGYLP
>Mature_515_residues
TRTRLLQQLEEEKCWDLLVIGGGATGLGVAVEGASRGYRTLLLERDDFGSGTSSRSTKLIHGGVRYLQQGNLSLVLEALH
ERGILIRNAPHLVHNLSFVVPLYDWWEGPFYGIGLKLYDMLAGKLGLGPSQILSREETLRRIPTVEPAGLRGGVIYHDGQ
FDDARLAVALARTCADLGGVPLNRMEVAGLLKGDGLVRGVAARDRESGREYEIEARVVVNATGPSCDAIRQLDDPGAQPV
IAPSQGVHLVLPREFLPGDSAIMVPHTDDGRVLFAVPWHERVIVGTTDTPVERVTAEPRPLAAEVGFLLEHAARYLSRDP
ATSDILSVFAGLRPLVRGEAVNTAALSRDHTIMVSTAGLVTITGGKWTTYRRMAEDTVNSAVRMAGLAERPSRTADLPIH
GWLAKGGVDGEWAMYGAEAAALEELCAVQPALRRQLHPRLPYRLAEVVWGVRYEWARSVEDVLSRRTRALILDARAAMEA
APEVAALMATELGRDEAWQAAEVAAFRALAEGYLP

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=545, Percent_Identity=41.1009174311927, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI285002231, Length=545, Percent_Identity=41.1009174311927, Blast_Score=403, Evalue=1e-112,
Organism=Escherichia coli, GI2367226, Length=467, Percent_Identity=31.2633832976445, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788574, Length=389, Percent_Identity=30.5912596401028, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17509253, Length=544, Percent_Identity=40.9926470588235, Blast_Score=356, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI115534726, Length=535, Percent_Identity=38.1308411214953, Blast_Score=338, Evalue=4e-93,
Organism=Saccharomyces cerevisiae, GI6322036, Length=593, Percent_Identity=34.7386172006745, Blast_Score=321, Evalue=2e-88,
Organism=Drosophila melanogaster, GI161077125, Length=523, Percent_Identity=40.9177820267686, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24653942, Length=523, Percent_Identity=40.9177820267686, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24653944, Length=523, Percent_Identity=40.9177820267686, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI20130025, Length=523, Percent_Identity=40.9177820267686, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI19921278, Length=547, Percent_Identity=33.45521023766, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24586295, Length=532, Percent_Identity=34.5864661654135, Blast_Score=278, Evalue=8e-75,
Organism=Drosophila melanogaster, GI45550977, Length=402, Percent_Identity=31.592039800995, Blast_Score=202, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56064; Mature: 55933

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTRLLQQLEEEKCWDLLVIGGGATGLGVAVEGASRGYRTLLLERDDFGSGTSSRSTKL
CCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCHH
IHGGVRYLQQGNLSLVLEALHERGILIRNAPHLVHNLSFVVPLYDWWEGPFYGIGLKLYD
HHHHHHHHHCCCHHHHHHHHHHCCEEEECCCHHHHCCEEEEEHHHHCCCCEEECHHHHHH
MLAGKLGLGPSQILSREETLRRIPTVEPAGLRGGVIYHDGQFDDARLAVALARTCADLGG
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCC
VPLNRMEVAGLLKGDGLVRGVAARDRESGREYEIEARVVVNATGPSCDAIRQLDDPGAQP
CCCCHHHHHHEECCCCEEEEHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHHCCCCCCCC
VIAPSQGVHLVLPREFLPGDSAIMVPHTDDGRVLFAVPWHERVIVGTTDTPVERVTAEPR
EECCCCCEEEEECHHHCCCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCHHHHCCCCC
PLAAEVGFLLEHAARYLSRDPATSDILSVFAGLRPLVRGEAVNTAALSRDHTIMVSTAGL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECCE
VTITGGKWTTYRRMAEDTVNSAVRMAGLAERPSRTADLPIHGWLAKGGVDGEWAMYGAEA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEECCHH
AALEELCAVQPALRRQLHPRLPYRLAEVVWGVRYEWARSVEDVLSRRTRALILDARAAME
HHHHHHHHCCHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEHHHHHH
AAPEVAALMATELGRDEAWQAAEVAAFRALAEGYLP
HCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRTRLLQQLEEEKCWDLLVIGGGATGLGVAVEGASRGYRTLLLERDDFGSGTSSRSTKL
CHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCHH
IHGGVRYLQQGNLSLVLEALHERGILIRNAPHLVHNLSFVVPLYDWWEGPFYGIGLKLYD
HHHHHHHHHCCCHHHHHHHHHHCCEEEECCCHHHHCCEEEEEHHHHCCCCEEECHHHHHH
MLAGKLGLGPSQILSREETLRRIPTVEPAGLRGGVIYHDGQFDDARLAVALARTCADLGG
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCC
VPLNRMEVAGLLKGDGLVRGVAARDRESGREYEIEARVVVNATGPSCDAIRQLDDPGAQP
CCCCHHHHHHEECCCCEEEEHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHHCCCCCCCC
VIAPSQGVHLVLPREFLPGDSAIMVPHTDDGRVLFAVPWHERVIVGTTDTPVERVTAEPR
EECCCCCEEEEECHHHCCCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCHHHHCCCCC
PLAAEVGFLLEHAARYLSRDPATSDILSVFAGLRPLVRGEAVNTAALSRDHTIMVSTAGL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECCE
VTITGGKWTTYRRMAEDTVNSAVRMAGLAERPSRTADLPIHGWLAKGGVDGEWAMYGAEA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEECCHH
AALEELCAVQPALRRQLHPRLPYRLAEVVWGVRYEWARSVEDVLSRRTRALILDARAAME
HHHHHHHHCCHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEHHHHHH
AAPEVAALMATELGRDEAWQAAEVAAFRALAEGYLP
HCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]