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The map label for this gene is mtaD [H]

Identifier: 78222854

GI number: 78222854

Start: 1846748

End: 1848013

Strand: Direct

Name: mtaD [H]

Synonym: Gmet_1645

Alternate gene names: 78222854

Gene position: 1846748-1848013 (Clockwise)

Preceding gene: 78222853

Following gene: 78222855

Centisome position: 46.2

GC content: 58.77

Gene sequence:

>1266_bases
ATGGAACTTTACGCCGCTTCATACATTCTGCCGATAGCATCTCCCCCCATCCCCGGCGGCGCGGTGGCTGTCCACGACGG
CTGCATTGTCGAAACGGGAACGCTGGCCGAGCTCCGTTCGCGCCATAGCGGTCCCGTCCATGATTTCCCCGGTTGCGCCA
TCCTCCCCGGGCTCGTCAACGCCCACACCCACCTGGAGCTTACCCATTTCCCTTCCTGGAAGATCCGCAAGGGGATTGAC
TATTCTCCTCGAACATACGTGGACTGGATAATCCAGGTAATCAAGATCCGGCGGGCCTTGTCGCCACAGGAACTGGAGCT
TTCCGTGCGCGAGGGGCTGCGGATTTGCCTCGAAGCCGGGACTACAGCCATCGGCGAAATCCTCACCGACCGTTCACTTA
TCCCCCTCTATGCCGATTCAGGCCTGAGAGGGAGGCTCTTATTCGAGGCCATCGGTCACGACCCGGTTCGCAATGCCCAA
CTCGTCGAAGAACTTGATGCTGCCATCGCTTCCTTTTCCGGAGGCTCATTTCTCCCGGGCATTTCACCCCATGCTCCCCA
CACCGTTGCCGAACACCTACACCAGGATGTGTACCGTCTGGCGTATGAGCGGAACGTGCCACGAGTCATCCACCTGGCCG
AGTCCCGCGAAGAGAGCGATTTTTTCTTTGATTCTTCCGGAAAAATTGCCGAGTTTCTCTATCCCCATGTCCGGTGGGAA
TCGTACCTCCCCGCACCACGGCGCACAACCGCTACAGCCTGGCTCGATGGGCTCGGCGTATTGAACGGCACCATCTCGGC
TGTTCACTGCGTTCACCTTACGCCGTCCGACGCCGAAATCCTGGCCAAACGTGGCGTCGGCGTGGTCCTCTGTCCCCGGA
GCAACGACAAACTCGCCGTGGGGCGCGCCCCGGTCGTTCTGCTGAAGAGGCTCGGCGTCCCGCTTGCGCTTGGCACCGAT
TCACTGGCCAGCAATGACTCACTCTCACTGTGGGATGAAATGCGATATCTCCTTGATACCTTCCCGGGCATTTTTACTCC
TACGGAAGCCCTTTCAATGACCACCATCGGCTCTGCTCGCCAGTTAGCCCTTGCTGATCGGACCGGTTCCCTCGATAAAG
GGAAACATGCCGATTTCCTTGTGATGAAGCTCCCGGGCCGGAATGGTTCCGGTGAGGCGCTGCATGAGGCGCTCATTCAT
TCGGGAGAGATTCTTCAGGTTTTCCTTGCCGGCAATCTCGTTGTTAGCCGGGAGGCGTTTTCTTGA

Upstream 100 bases:

>100_bases
GGTCTGGCGAAAGCTGTCTAACGGTAGTTTGATGGAGTTGGTGTTCTTTTGTGGTAGAGTGTAATGACTGAGTAAAGACC
CGTTGCCGAGAGCCCTTTCG

Downstream 100 bases:

>100_bases
CCGTGCGCAAACCTCTTTTTTCCTGTAATTGCAAGGGCTTTTTACTCCTTGCAATGATTTCGCCATATCTGCTACTATCA
CTTTCATGGGAGAAAAGCTG

Product: Atz/Trz family chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MELYAASYILPIASPPIPGGAVAVHDGCIVETGTLAELRSRHSGPVHDFPGCAILPGLVNAHTHLELTHFPSWKIRKGID
YSPRTYVDWIIQVIKIRRALSPQELELSVREGLRICLEAGTTAIGEILTDRSLIPLYADSGLRGRLLFEAIGHDPVRNAQ
LVEELDAAIASFSGGSFLPGISPHAPHTVAEHLHQDVYRLAYERNVPRVIHLAESREESDFFFDSSGKIAEFLYPHVRWE
SYLPAPRRTTATAWLDGLGVLNGTISAVHCVHLTPSDAEILAKRGVGVVLCPRSNDKLAVGRAPVVLLKRLGVPLALGTD
SLASNDSLSLWDEMRYLLDTFPGIFTPTEALSMTTIGSARQLALADRTGSLDKGKHADFLVMKLPGRNGSGEALHEALIH
SGEILQVFLAGNLVVSREAFS

Sequences:

>Translated_421_residues
MELYAASYILPIASPPIPGGAVAVHDGCIVETGTLAELRSRHSGPVHDFPGCAILPGLVNAHTHLELTHFPSWKIRKGID
YSPRTYVDWIIQVIKIRRALSPQELELSVREGLRICLEAGTTAIGEILTDRSLIPLYADSGLRGRLLFEAIGHDPVRNAQ
LVEELDAAIASFSGGSFLPGISPHAPHTVAEHLHQDVYRLAYERNVPRVIHLAESREESDFFFDSSGKIAEFLYPHVRWE
SYLPAPRRTTATAWLDGLGVLNGTISAVHCVHLTPSDAEILAKRGVGVVLCPRSNDKLAVGRAPVVLLKRLGVPLALGTD
SLASNDSLSLWDEMRYLLDTFPGIFTPTEALSMTTIGSARQLALADRTGSLDKGKHADFLVMKLPGRNGSGEALHEALIH
SGEILQVFLAGNLVVSREAFS
>Mature_421_residues
MELYAASYILPIASPPIPGGAVAVHDGCIVETGTLAELRSRHSGPVHDFPGCAILPGLVNAHTHLELTHFPSWKIRKGID
YSPRTYVDWIIQVIKIRRALSPQELELSVREGLRICLEAGTTAIGEILTDRSLIPLYADSGLRGRLLFEAIGHDPVRNAQ
LVEELDAAIASFSGGSFLPGISPHAPHTVAEHLHQDVYRLAYERNVPRVIHLAESREESDFFFDSSGKIAEFLYPHVRWE
SYLPAPRRTTATAWLDGLGVLNGTISAVHCVHLTPSDAEILAKRGVGVVLCPRSNDKLAVGRAPVVLLKRLGVPLALGTD
SLASNDSLSLWDEMRYLLDTFPGIFTPTEALSMTTIGSARQLALADRTGSLDKGKHADFLVMKLPGRNGSGEALHEALIH
SGEILQVFLAGNLVVSREAFS

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319963, Length=361, Percent_Identity=23.2686980609418, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 45735; Mature: 45735

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELYAASYILPIASPPIPGGAVAVHDGCIVETGTLAELRSRHSGPVHDFPGCAILPGLVN
CCEEECEEEEECCCCCCCCCEEEEECCEEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHC
AHTHLELTHFPSWKIRKGIDYSPRTYVDWIIQVIKIRRALSPQELELSVREGLRICLEAG
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
TTAIGEILTDRSLIPLYADSGLRGRLLFEAIGHDPVRNAQLVEELDAAIASFSGGSFLPG
CHHHHHHHCCCCEEEEEECCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
ISPHAPHTVAEHLHQDVYRLAYERNVPRVIHLAESREESDFFFDSSGKIAEFLYPHVRWE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEECCCCCHHHHHCCHHCHH
SYLPAPRRTTATAWLDGLGVLNGTISAVHCVHLTPSDAEILAKRGVGVVLCPRSNDKLAV
HCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHCCCEEEEECCCCCCEEE
GRAPVVLLKRLGVPLALGTDSLASNDSLSLWDEMRYLLDTFPGIFTPTEALSMTTIGSAR
CCCHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCCC
QLALADRTGSLDKGKHADFLVMKLPGRNGSGEALHEALIHSGEILQVFLAGNLVVSREAF
EEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCEEEECCCC
S
C
>Mature Secondary Structure
MELYAASYILPIASPPIPGGAVAVHDGCIVETGTLAELRSRHSGPVHDFPGCAILPGLVN
CCEEECEEEEECCCCCCCCCEEEEECCEEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHC
AHTHLELTHFPSWKIRKGIDYSPRTYVDWIIQVIKIRRALSPQELELSVREGLRICLEAG
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
TTAIGEILTDRSLIPLYADSGLRGRLLFEAIGHDPVRNAQLVEELDAAIASFSGGSFLPG
CHHHHHHHCCCCEEEEEECCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
ISPHAPHTVAEHLHQDVYRLAYERNVPRVIHLAESREESDFFFDSSGKIAEFLYPHVRWE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEECCCCCHHHHHCCHHCHH
SYLPAPRRTTATAWLDGLGVLNGTISAVHCVHLTPSDAEILAKRGVGVVLCPRSNDKLAV
HCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHCCCEEEEECCCCCCEEE
GRAPVVLLKRLGVPLALGTDSLASNDSLSLWDEMRYLLDTFPGIFTPTEALSMTTIGSAR
CCCHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCCC
QLALADRTGSLDKGKHADFLVMKLPGRNGSGEALHEALIHSGEILQVFLAGNLVVSREAF
EEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCEEEECCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA