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The map label for this gene is argK [C]

Identifier: 78222786

GI number: 78222786

Start: 1776123

End: 1777085

Strand: Direct

Name: argK [C]

Synonym: Gmet_1576

Alternate gene names: 78222786

Gene position: 1776123-1777085 (Clockwise)

Preceding gene: 78222785

Following gene: 78222787

Centisome position: 44.43

GC content: 59.61

Gene sequence:

>963_bases
ATGTCTTTGGCTCAGAGGATACTTGACAGCGATTTACGTGCCGCGGCCCGTCTCATGCGAGATCTGGACGATGGATTTCG
GAGCGCTGCCGAGGAGATGAAGAGTCTCTATCCCCACACCGGGCGTGCGTTCATACTGGGCATCACTGGACCTCCGGGGG
CAGGTAAATCGACCCTGGTCGATCAGCTCACTGCCGCCTATCGTCAACGGGGGCGCAGGGTGGGGGTGGTGGCCATCGAT
CCCACAAGCCCCTTTACGGGGGGGGCGATTCTTGGCGACCGGATCAGGATGAACCGCCATGCCGAAGATCCCGGCGTTTT
TATCCGGAGTCTCGCCACCCGTGGGCATATGGGGGGACTTTCCCGCTCCACCGGCGACGTGGTGAACGTTATGGATGCCA
TGGGGATGGATGTGGTCATCATCGAGACTGTCGGCGTTGGGCAGGATGAGATCGATATTGTCCGTATGGCCCATACGACC
GTGGTTGTTTCGGTGCCGGGCCTGGGTGACGACATCCAGGCCATCAAGGCGGGAGTGCTCGAAATCGGCGATCTCTTCGT
GGTCAACAAGGCCGACCGGGAAGGGGCTGACCGGACTGCCCGCGAGCTTGCTGCCATGCTGGAGATGAAGCAGGCCAAAC
CGGGCGATTGGCAGCCGAAGGTGCTCCTTACCGAGGCAAGCCGCAACAAGGGCATCGAAGAATTGGTGGATGAGATCGAG
GCACACCACGGCCATCTCGTGAATTCCGGGGCCCTTGAACGTCTTAAGGAAGAGCGGTGCGCGCGGCAGTTCATGGATTT
ACTGCGGGAACGGCTCTTTGCCGAAGTCTATGGCCATATACATGTAAATGGCCGCTTTAGGGAAATCGTCGAGGATATGG
CGGCGCGTCGGACCGATCCGTACAGTGCCGTGGAGATGATAATCGCTGAACGGTTCTCGGGACGACAGGCGTCTAACCCT
TGA

Upstream 100 bases:

>100_bases
CTGAAGACCGGCTGCGCCCTCGAGGCAGCGTCTTATGCGTATCTCTTTGCCACGTCGACTGAGCGGGGGCGAATGACTGA
ATTTTTGGAAGGAACGACGA

Downstream 100 bases:

>100_bases
CCGTAGCGAAGAAAAGTGTTAGTTTCCGCGTAACGTAAATGGGGCTTCGGCCCCTTTCCTTTTTTCTGCAGGACTGGTAC
CTCATGATCCGCAAGCTGGC

Product: ArgK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSLAQRILDSDLRAAARLMRDLDDGFRSAAEEMKSLYPHTGRAFILGITGPPGAGKSTLVDQLTAAYRQRGRRVGVVAID
PTSPFTGGAILGDRIRMNRHAEDPGVFIRSLATRGHMGGLSRSTGDVVNVMDAMGMDVVIIETVGVGQDEIDIVRMAHTT
VVVSVPGLGDDIQAIKAGVLEIGDLFVVNKADREGADRTARELAAMLEMKQAKPGDWQPKVLLTEASRNKGIEELVDEIE
AHHGHLVNSGALERLKEERCARQFMDLLRERLFAEVYGHIHVNGRFREIVEDMAARRTDPYSAVEMIIAERFSGRQASNP

Sequences:

>Translated_320_residues
MSLAQRILDSDLRAAARLMRDLDDGFRSAAEEMKSLYPHTGRAFILGITGPPGAGKSTLVDQLTAAYRQRGRRVGVVAID
PTSPFTGGAILGDRIRMNRHAEDPGVFIRSLATRGHMGGLSRSTGDVVNVMDAMGMDVVIIETVGVGQDEIDIVRMAHTT
VVVSVPGLGDDIQAIKAGVLEIGDLFVVNKADREGADRTARELAAMLEMKQAKPGDWQPKVLLTEASRNKGIEELVDEIE
AHHGHLVNSGALERLKEERCARQFMDLLRERLFAEVYGHIHVNGRFREIVEDMAARRTDPYSAVEMIIAERFSGRQASNP
>Mature_319_residues
SLAQRILDSDLRAAARLMRDLDDGFRSAAEEMKSLYPHTGRAFILGITGPPGAGKSTLVDQLTAAYRQRGRRVGVVAIDP
TSPFTGGAILGDRIRMNRHAEDPGVFIRSLATRGHMGGLSRSTGDVVNVMDAMGMDVVIIETVGVGQDEIDIVRMAHTTV
VVSVPGLGDDIQAIKAGVLEIGDLFVVNKADREGADRTARELAAMLEMKQAKPGDWQPKVLLTEASRNKGIEELVDEIEA
HHGHLVNSGALERLKEERCARQFMDLLRERLFAEVYGHIHVNGRFREIVEDMAARRTDPYSAVEMIIAERFSGRQASNP

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=240, Percent_Identity=33.75, Blast_Score=159, Evalue=3e-39,
Organism=Escherichia coli, GI1789285, Length=259, Percent_Identity=37.8378378378378, Blast_Score=182, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71994271, Length=289, Percent_Identity=30.4498269896194, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71994275, Length=294, Percent_Identity=29.9319727891156, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35049; Mature: 34917

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAQRILDSDLRAAARLMRDLDDGFRSAAEEMKSLYPHTGRAFILGITGPPGAGKSTLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHH
DQLTAAYRQRGRRVGVVAIDPTSPFTGGAILGDRIRMNRHAEDPGVFIRSLATRGHMGGL
HHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
SRSTGDVVNVMDAMGMDVVIIETVGVGQDEIDIVRMAHTTVVVSVPGLGDDIQAIKAGVL
CCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHEEEEEEEEEECCCCCHHHHHHHHHHH
EIGDLFVVNKADREGADRTARELAAMLEMKQAKPGDWQPKVLLTEASRNKGIEELVDEIE
HHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHH
AHHGHLVNSGALERLKEERCARQFMDLLRERLFAEVYGHIHVNGRFREIVEDMAARRTDP
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHCCCCH
YSAVEMIIAERFSGRQASNP
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SLAQRILDSDLRAAARLMRDLDDGFRSAAEEMKSLYPHTGRAFILGITGPPGAGKSTLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHH
DQLTAAYRQRGRRVGVVAIDPTSPFTGGAILGDRIRMNRHAEDPGVFIRSLATRGHMGGL
HHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
SRSTGDVVNVMDAMGMDVVIIETVGVGQDEIDIVRMAHTTVVVSVPGLGDDIQAIKAGVL
CCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHEEEEEEEEEECCCCCHHHHHHHHHHH
EIGDLFVVNKADREGADRTARELAAMLEMKQAKPGDWQPKVLLTEASRNKGIEELVDEIE
HHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHH
AHHGHLVNSGALERLKEERCARQFMDLLRERLFAEVYGHIHVNGRFREIVEDMAARRTDP
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHCCCCH
YSAVEMIIAERFSGRQASNP
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]