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The map label for this gene is crt [H]

Identifier: 78222785

GI number: 78222785

Start: 1775360

End: 1776148

Strand: Direct

Name: crt [H]

Synonym: Gmet_1575

Alternate gene names: 78222785

Gene position: 1775360-1776148 (Clockwise)

Preceding gene: 78222784

Following gene: 78222786

Centisome position: 44.41

GC content: 56.53

Gene sequence:

>789_bases
ATGCCGTATAAAAAACTTCGTATCGAGATCCGCAATAAAGTCGGTTACATCCTGCTGTGTTCCGGCCAGCGTTTCAATAA
ACTCAGCATTACCACACTGAGAGAAGTGAAACGGGCCATCACCGAACTTTCGCACAACCCCGAGGCGGTTTGTCTCGTCA
TCACCGGTTATCCGGGCGAATCCTTCGCCGTCGGCGCCGATATCTCCCAAATGGCGGAGTTCGGTCCTGCCGACGGCTTT
TCCTTTGGCGAGCTCGGGCAATCATTGTTCGAGGCAATGGAGTCGTGTCCCAAGCCAGTCATCGGCGCTCTTAACGGAAT
TACCATGGGGGGTGGATGCGACCTGGCACTTGCCTGTGACCTGAGGATCGCCAGCGATGCACTCGTCATTGCACACCCTG
GCGCAAAACTGGGTATAATTACCGGTTTTTGCGGCACCCAGAAGCTGCCACGTCTGGTGGGGAGAAATTACGCCCGGGAA
ATCTTCATGACCTCCGAACCTTACCGCGCTGCCGATGCCCTGCGGATGGGACTCGTGGACCGGGTATACCCAGCCGGTGA
ATTCTGGGAGCGGGTCGTGGCTTTTGCGGAGCGGATCGCTAAAGTCTCGCCCGCTGCCCTTGCCATGGCAAAGAAGGCGA
TCAATGCCGCCGAGGACTGTGACCTGAAGACCGGCTGCGCCCTCGAGGCAGCGTCTTATGCGTATCTCTTTGCCACGTCG
ACTGAGCGGGGGCGAATGACTGAATTTTTGGAAGGAACGACGAATGTCTTTGGCTCAGAGGATACTTGA

Upstream 100 bases:

>100_bases
GGGCTGGCGTCAGCGAGGTATTTACGCCGGGAACCTCAACTGAGTCCATTGTGCAGTGGGTGCGTGAAAACGTGGCCCCG
CGCGCATAGTACGTTATCCC

Downstream 100 bases:

>100_bases
CAGCGATTTACGTGCCGCGGCCCGTCTCATGCGAGATCTGGACGATGGATTTCGGAGCGCTGCCGAGGAGATGAAGAGTC
TCTATCCCCACACCGGGCGT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPYKKLRIEIRNKVGYILLCSGQRFNKLSITTLREVKRAITELSHNPEAVCLVITGYPGESFAVGADISQMAEFGPADGF
SFGELGQSLFEAMESCPKPVIGALNGITMGGGCDLALACDLRIASDALVIAHPGAKLGIITGFCGTQKLPRLVGRNYARE
IFMTSEPYRAADALRMGLVDRVYPAGEFWERVVAFAERIAKVSPAALAMAKKAINAAEDCDLKTGCALEAASYAYLFATS
TERGRMTEFLEGTTNVFGSEDT

Sequences:

>Translated_262_residues
MPYKKLRIEIRNKVGYILLCSGQRFNKLSITTLREVKRAITELSHNPEAVCLVITGYPGESFAVGADISQMAEFGPADGF
SFGELGQSLFEAMESCPKPVIGALNGITMGGGCDLALACDLRIASDALVIAHPGAKLGIITGFCGTQKLPRLVGRNYARE
IFMTSEPYRAADALRMGLVDRVYPAGEFWERVVAFAERIAKVSPAALAMAKKAINAAEDCDLKTGCALEAASYAYLFATS
TERGRMTEFLEGTTNVFGSEDT
>Mature_261_residues
PYKKLRIEIRNKVGYILLCSGQRFNKLSITTLREVKRAITELSHNPEAVCLVITGYPGESFAVGADISQMAEFGPADGFS
FGELGQSLFEAMESCPKPVIGALNGITMGGGCDLALACDLRIASDALVIAHPGAKLGIITGFCGTQKLPRLVGRNYAREI
FMTSEPYRAADALRMGLVDRVYPAGEFWERVVAFAERIAKVSPAALAMAKKAINAAEDCDLKTGCALEAASYAYLFATST
ERGRMTEFLEGTTNVFGSEDT

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=240, Percent_Identity=35.4166666666667, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI31542718, Length=256, Percent_Identity=28.90625, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI68989263, Length=200, Percent_Identity=30.5, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI20127408, Length=208, Percent_Identity=31.25, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4502327, Length=230, Percent_Identity=28.695652173913, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI70995211, Length=223, Percent_Identity=28.6995515695067, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI37594471, Length=151, Percent_Identity=29.1390728476821, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI37594469, Length=151, Percent_Identity=29.1390728476821, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI213417737, Length=177, Percent_Identity=23.728813559322, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI157694516, Length=177, Percent_Identity=23.728813559322, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI260274832, Length=241, Percent_Identity=24.0663900414938, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI45643119, Length=224, Percent_Identity=24.5535714285714, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI260275230, Length=224, Percent_Identity=24.5535714285714, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221136756, Length=260, Percent_Identity=21.1538461538462, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI221136753, Length=260, Percent_Identity=21.1538461538462, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI62530384, Length=228, Percent_Identity=22.8070175438596, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787659, Length=232, Percent_Identity=34.051724137931, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788597, Length=231, Percent_Identity=30.3030303030303, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=32.6530612244898, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790281, Length=219, Percent_Identity=32.4200913242009, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082183, Length=215, Percent_Identity=25.5813953488372, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI221142681, Length=187, Percent_Identity=32.0855614973262, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=239, Percent_Identity=32.2175732217573, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17554946, Length=241, Percent_Identity=33.195020746888, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17540714, Length=211, Percent_Identity=30.3317535545024, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17536985, Length=227, Percent_Identity=28.6343612334802, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=233, Percent_Identity=26.6094420600858, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=217, Percent_Identity=26.7281105990783, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17558304, Length=198, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17508951, Length=218, Percent_Identity=30.7339449541284, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25144276, Length=218, Percent_Identity=30.7339449541284, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17508953, Length=218, Percent_Identity=30.7339449541284, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=201, Percent_Identity=27.8606965174129, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129971, Length=251, Percent_Identity=31.4741035856574, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653477, Length=251, Percent_Identity=31.4741035856574, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653139, Length=240, Percent_Identity=30.4166666666667, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=28.8372093023256, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24654903, Length=203, Percent_Identity=28.0788177339901, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24650670, Length=264, Percent_Identity=26.1363636363636, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583077, Length=182, Percent_Identity=34.0659340659341, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583079, Length=182, Percent_Identity=34.0659340659341, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921000, Length=182, Percent_Identity=34.0659340659341, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583165, Length=247, Percent_Identity=24.2914979757085, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922422, Length=213, Percent_Identity=23.4741784037559, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357171, Length=216, Percent_Identity=25, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921018, Length=206, Percent_Identity=25.2427184466019, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28215; Mature: 28084

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYKKLRIEIRNKVGYILLCSGQRFNKLSITTLREVKRAITELSHNPEAVCLVITGYPGE
CCCHHHEEEEECCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
SFAVGADISQMAEFGPADGFSFGELGQSLFEAMESCPKPVIGALNGITMGGGCDLALACD
CEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCEEECCCCCEEEEEE
LRIASDALVIAHPGAKLGIITGFCGTQKLPRLVGRNYAREIFMTSEPYRAADALRMGLVD
EEECCCEEEEECCCCCEEEEECCCCCHHHHHHHCCHHHHHEEECCCCHHHHHHHHHHHHH
RVYPAGEFWERVVAFAERIAKVSPAALAMAKKAINAAEDCDLKTGCALEAASYAYLFATS
HCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHCCCCCCCCCCHHCCEEEEEEEC
TERGRMTEFLEGTTNVFGSEDT
CCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PYKKLRIEIRNKVGYILLCSGQRFNKLSITTLREVKRAITELSHNPEAVCLVITGYPGE
CCHHHEEEEECCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
SFAVGADISQMAEFGPADGFSFGELGQSLFEAMESCPKPVIGALNGITMGGGCDLALACD
CEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCEEECCCCCEEEEEE
LRIASDALVIAHPGAKLGIITGFCGTQKLPRLVGRNYAREIFMTSEPYRAADALRMGLVD
EEECCCEEEEECCCCCEEEEECCCCCHHHHHHHCCHHHHHEEECCCCHHHHHHHHHHHHH
RVYPAGEFWERVVAFAERIAKVSPAALAMAKKAINAAEDCDLKTGCALEAASYAYLFATS
HCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHCCCCCCCCCCHHCCEEEEEEEC
TERGRMTEFLEGTTNVFGSEDT
CCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]