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The map label for this gene is exoB [H]

Identifier: 78222698

GI number: 78222698

Start: 1679853

End: 1680845

Strand: Direct

Name: exoB [H]

Synonym: Gmet_1486

Alternate gene names: 78222698

Gene position: 1679853-1680845 (Clockwise)

Preceding gene: 78222697

Following gene: 78222699

Centisome position: 42.02

GC content: 62.34

Gene sequence:

>993_bases
ATGAAGATATTGGTCACCGGCGGTGCCGGCTACATAGGAAGTCACGTGGTGAAGGCCCTTGGCCTGGAGGGGCATGAGCT
GCTCGTGTACGACAACCTCTCCACGGGGCACGAGTGGGCGGTCATGTACGGCACTCTCGTCAAGGGAGATCTGGAGGACC
GGGCTCTGCTGGAAAAGGTCTTCCGCGAGTTCCGTCCCGACGCGGTGATGCACTTTGCCGCATCCATCCAGGTGGAGGAA
TCGGTTCGCCGGCCGCTTCTCTACTACGGCAACAACACGGCCGGCACCCTGAATCTCCTCGATGTAATGGTCAGGACGGG
GGTGCGATGCCTGGTGCATTCCTCCACTGCGGCGGTCTACGGGATTCCGGATGTGGTGCCGGTCGCCGAAACCGCTCCCC
TTGCTCCCATCAACCCCTACGGCTCATCAAAGGCCATGGTGGAAAAAATTCTTGCCGACCTTGCACTGGCCGAGGATTTC
CGCTACGTGGCCATCCGCTACTTCAATGTGGCCGGCGCCGATGTGGCGTGCCGCCTGGGCCAGGCCTACCGTGAGGCGAC
TCACCTCATCACCCGGGCGCTCAAGACCGCCCACGGCCAGTACGAACGGCTCCAGATCTTCGGGACCGACTACCAGACTC
CCGACGGCACCTGTATCCGTGATTACATCCACGTGGACGACCTTGCCGCCGCCCATGTTCTGGCCCTGGATTACCTGACT
GAGGGAGGCGCGAGCGAGATCGTCAACTGCGGCTACGGGCACGGATTTTCGGTGCGTGAGGTGATCGAGGCCGTGGCGCA
TGTTACCGGCACCCCTTTTCCGGTAGAGGAAACGGGGCGGCGGCCGGGTGACCCGCCGGCCCTGGTCGCGGACAGCTCCA
AACTCCGATCCCTCATGAAGTGGGAGCCCCAATACGACAATCTCGACTTCATCATCAGGACTGCCTGGGAATGGGAGCTG
GCTCTCAAGCGGAGGGAGTCATGTGCGGCATAG

Upstream 100 bases:

>100_bases
GGGCTCGTCTCCACCCAACAGCAGGGCGAGGGAACTTTGACGGAGGTGGCTGCCAGATGACGGCGCGCCACGACACAAGG
CCGGAACAGGGAGGGTCACG

Downstream 100 bases:

>100_bases
TTGGCTACACGGGGCGTCAGCCGGCGGTCCCCGTCATCCTCGAAGGTCTGCGGCGCCTGGAGTACCGGGGGTATGACTCG
GCAGGCATCTGCACCATGAA

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKILVTGGAGYIGSHVVKALGLEGHELLVYDNLSTGHEWAVMYGTLVKGDLEDRALLEKVFREFRPDAVMHFAASIQVEE
SVRRPLLYYGNNTAGTLNLLDVMVRTGVRCLVHSSTAAVYGIPDVVPVAETAPLAPINPYGSSKAMVEKILADLALAEDF
RYVAIRYFNVAGADVACRLGQAYREATHLITRALKTAHGQYERLQIFGTDYQTPDGTCIRDYIHVDDLAAAHVLALDYLT
EGGASEIVNCGYGHGFSVREVIEAVAHVTGTPFPVEETGRRPGDPPALVADSSKLRSLMKWEPQYDNLDFIIRTAWEWEL
ALKRRESCAA

Sequences:

>Translated_330_residues
MKILVTGGAGYIGSHVVKALGLEGHELLVYDNLSTGHEWAVMYGTLVKGDLEDRALLEKVFREFRPDAVMHFAASIQVEE
SVRRPLLYYGNNTAGTLNLLDVMVRTGVRCLVHSSTAAVYGIPDVVPVAETAPLAPINPYGSSKAMVEKILADLALAEDF
RYVAIRYFNVAGADVACRLGQAYREATHLITRALKTAHGQYERLQIFGTDYQTPDGTCIRDYIHVDDLAAAHVLALDYLT
EGGASEIVNCGYGHGFSVREVIEAVAHVTGTPFPVEETGRRPGDPPALVADSSKLRSLMKWEPQYDNLDFIIRTAWEWEL
ALKRRESCAA
>Mature_330_residues
MKILVTGGAGYIGSHVVKALGLEGHELLVYDNLSTGHEWAVMYGTLVKGDLEDRALLEKVFREFRPDAVMHFAASIQVEE
SVRRPLLYYGNNTAGTLNLLDVMVRTGVRCLVHSSTAAVYGIPDVVPVAETAPLAPINPYGSSKAMVEKILADLALAEDF
RYVAIRYFNVAGADVACRLGQAYREATHLITRALKTAHGQYERLQIFGTDYQTPDGTCIRDYIHVDDLAAAHVLALDYLT
EGGASEIVNCGYGHGFSVREVIEAVAHVTGTPFPVEETGRRPGDPPALVADSSKLRSLMKWEPQYDNLDFIIRTAWEWEL
ALKRRESCAA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=335, Percent_Identity=37.0149253731343, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI56118217, Length=335, Percent_Identity=37.0149253731343, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI189083684, Length=335, Percent_Identity=37.0149253731343, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI7657641, Length=334, Percent_Identity=26.3473053892216, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786974, Length=330, Percent_Identity=38.7878787878788, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1788353, Length=358, Percent_Identity=28.2122905027933, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994969, Length=353, Percent_Identity=26.9121813031161, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790049, Length=290, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982038, Length=341, Percent_Identity=36.0703812316716, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=36.5781710914454, Blast_Score=197, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=28.9230769230769, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17539532, Length=337, Percent_Identity=25.8160237388724, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=40, Blast_Score=216, Evalue=6e-57,
Organism=Drosophila melanogaster, GI19923002, Length=336, Percent_Identity=35.4166666666667, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=28.1553398058252, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36269; Mature: 36269

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVTGGAGYIGSHVVKALGLEGHELLVYDNLSTGHEWAVMYGTLVKGDLEDRALLEKV
CEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEHHHCCCCHHHHHHHHH
FREFRPDAVMHFAASIQVEESVRRPLLYYGNNTAGTLNLLDVMVRTGVRCLVHSSTAAVY
HHHHCCHHHHHHHHHEEEHHHHCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCEEEE
GIPDVVPVAETAPLAPINPYGSSKAMVEKILADLALAEDFRYVAIRYFNVAGADVACRLG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHH
QAYREATHLITRALKTAHGQYERLQIFGTDYQTPDGTCIRDYIHVDDLAAAHVLALDYLT
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGGASEIVNCGYGHGFSVREVIEAVAHVTGTPFPVEETGRRPGDPPALVADSSKLRSLMK
CCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCEEEECCHHHHHHHH
WEPQYDNLDFIIRTAWEWELALKRRESCAA
CCCCCCCCEEEEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILVTGGAGYIGSHVVKALGLEGHELLVYDNLSTGHEWAVMYGTLVKGDLEDRALLEKV
CEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEHHHCCCCHHHHHHHHH
FREFRPDAVMHFAASIQVEESVRRPLLYYGNNTAGTLNLLDVMVRTGVRCLVHSSTAAVY
HHHHCCHHHHHHHHHEEEHHHHCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCEEEE
GIPDVVPVAETAPLAPINPYGSSKAMVEKILADLALAEDFRYVAIRYFNVAGADVACRLG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHH
QAYREATHLITRALKTAHGQYERLQIFGTDYQTPDGTCIRDYIHVDDLAAAHVLALDYLT
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGGASEIVNCGYGHGFSVREVIEAVAHVTGTPFPVEETGRRPGDPPALVADSSKLRSLMK
CCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCEEEECCHHHHHHHH
WEPQYDNLDFIIRTAWEWELALKRRESCAA
CCCCCCCCEEEEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]