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The map label for this gene is tolQ [H]

Identifier: 78222671

GI number: 78222671

Start: 1638442

End: 1640253

Strand: Direct

Name: tolQ [H]

Synonym: Gmet_1459

Alternate gene names: 78222671

Gene position: 1638442-1640253 (Clockwise)

Preceding gene: 78222670

Following gene: 78222672

Centisome position: 40.99

GC content: 63.85

Gene sequence:

>1812_bases
ATGAGCACACCTGAACGGAGGAGCATGATGAACAGCAGGATGTTTGGGCGTTTTGCGCGGGTGACGCTGGCAGCGGCGGC
GCTGGTGATGACGGTGGCCGCGGTGCGGGCCGAGGCGTGGTGGGACGAGAAATGGCAGCAGCGGCGCAAGATCACCATCA
ATACGACGGCCCAGGGAGCGGAAGTGAAGGAGGCGGTTGCCGATGCGGCGGTGCTGGTCCGGCTCCACACGGGGAACTTC
AGCTTCACCACCGCGAAGCCCGACGGTTCCGACGTCCGCTTCGTGAGCGGCGACGACAAGACACCCCTCAAGTTCCACTT
CGAGATGTACGACGCGAAGAAGGAGATCGCCCTTGCCTGGGTGAAGGTGCCCCAGGTGGCGCCCAACTCGGGCCAGAACA
CGATCTGGGTGTACTACGGCAACAGTGGGGTCCAGGCGGCCCAGGACGTCGGCGGCACCTACGATACCCCCCAGGCACTG
GTCTACCATTTCAGCGAGACCCAAGGTGCGCCCCAGGATTCCTCTTCGTATAAGAATCACGCGAAGGAGTTTGCCGGCGG
GCTCGGCGCGCCGGCCCTGATCGGCGGCGGCGCAACGTTCAAGGGGGCGGAGCGGATCGTGGTTCCGGCGTCGCCGTCGC
TTTCGTTCCCCAAGGGCTTCTCCTTCTCTGTCTGGGTGAAGCCGGCCCAGCTTCAGGGTGAGGCCCATCTCTTCTCGTGG
GGTGACGGCGCCCAGGGCATCGTAGTGGGCCTTGATCAAAATGGTGCTGCCTTCGCCCGGGTGGGGCAGGCCGCTACGGG
CCGGACCCAGCCTCTGGCTTCCCAGAAATGGCACCACCTTGCCGTGGCTGCGGAGCCGGGCAAGCGTCTGGCGATCTACC
TCGACGGCCGCGAGGCCGCATCGTCGGCCATGCCGGCCTCTATGCCCGCGCCGGCGGGCGATGCATCCATCGGCGGCGGC
GCCCAGGGGGGTAACTTCTTTGCCGGCGAGATGGATGAGGTGACCCTGGCCAGTGTGGCCCGCTCGGCCTCGTGGTTTGC
CGCCGCTGCCGGAAGCCAGGGGCAGGAGGGGAAACTGGTGTCGTTGGCCCAGGAAGAGGCAGGGGGCAAGGGAGAGGCCG
ATCTCACCATCCATCTGATGAAGGTCATTGCCAAGAGCATCACCCTGGACGGCTGGGCCATCATTGGCCTCTGTACCTTC
ATGCTTTTCCTGGCCGCCGGGGTCTTTGTCTATAAATTTCTGGCCCTGCAGAAAATTGTCAAGGGGAATGAAATGTTCCT
CGAGAGCTTTGGCGAGCTTCACGACCCCCTGGCCCTGGAGGACACGGACGATGATCTGAAGCATTCGTCCATGTACCGGA
TCTACCAGGCCGGGAAGATCGAAATCGAGCGGTGGCTCGCCCGCCAGAGCGCGGATAAGGAGATAAGCAGCCTTTCTCCC
TCTGCCCTCAATATCTTCCGGTCGTCCCTCGACAAGGCCAATGTCAAGGAAAAGCAGAACCTCTCCTCCTGGCTCATCGT
CATGACGCTCGGCATCTCCGGCGGGCCGTTCTGGGGGCTGCTCGGCACGGTCTGGGGGGTCATGAACACCTTCGCCAGCC
TTGCCGAATCGGGCGAGGCGAACCTCACGGCCATCGCCCCGGGGGTCGCCTCGGCCCTGGCCTGCACCCTCTTCGGCCTC
TTCGTGGCCATTCCCGCGCTCTTTGCCTACAGCTACCTGACCAACCGGATGAAGAACCTGAACGCCGACACCCACGTCTT
TATCGACGAATACGCGGTGAAGGTTGAGGGCGTCTACGGAGAGAGAGCATGA

Upstream 100 bases:

>100_bases
AGAAGGATGAAACGTTCGTCACCTCATGGCTCGACGTGAAGGTAATTGGCTTCGATTCGGAAGATGGCAACGAAAAAGAC
AAGAAAAAGCAGGAGATGTG

Downstream 100 bases:

>100_bases
AAGCGCCTGCCGATGACATGGATGAAACGGTCGAGATAAACGTCGTACCGCTCCTGGACCTGGCCTGGAACCTCCTGGTG
GTGTTCATGATCGTGGTGAC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MSTPERRSMMNSRMFGRFARVTLAAAALVMTVAAVRAEAWWDEKWQQRRKITINTTAQGAEVKEAVADAAVLVRLHTGNF
SFTTAKPDGSDVRFVSGDDKTPLKFHFEMYDAKKEIALAWVKVPQVAPNSGQNTIWVYYGNSGVQAAQDVGGTYDTPQAL
VYHFSETQGAPQDSSSYKNHAKEFAGGLGAPALIGGGATFKGAERIVVPASPSLSFPKGFSFSVWVKPAQLQGEAHLFSW
GDGAQGIVVGLDQNGAAFARVGQAATGRTQPLASQKWHHLAVAAEPGKRLAIYLDGREAASSAMPASMPAPAGDASIGGG
AQGGNFFAGEMDEVTLASVARSASWFAAAAGSQGQEGKLVSLAQEEAGGKGEADLTIHLMKVIAKSITLDGWAIIGLCTF
MLFLAAGVFVYKFLALQKIVKGNEMFLESFGELHDPLALEDTDDDLKHSSMYRIYQAGKIEIERWLARQSADKEISSLSP
SALNIFRSSLDKANVKEKQNLSSWLIVMTLGISGGPFWGLLGTVWGVMNTFASLAESGEANLTAIAPGVASALACTLFGL
FVAIPALFAYSYLTNRMKNLNADTHVFIDEYAVKVEGVYGERA

Sequences:

>Translated_603_residues
MSTPERRSMMNSRMFGRFARVTLAAAALVMTVAAVRAEAWWDEKWQQRRKITINTTAQGAEVKEAVADAAVLVRLHTGNF
SFTTAKPDGSDVRFVSGDDKTPLKFHFEMYDAKKEIALAWVKVPQVAPNSGQNTIWVYYGNSGVQAAQDVGGTYDTPQAL
VYHFSETQGAPQDSSSYKNHAKEFAGGLGAPALIGGGATFKGAERIVVPASPSLSFPKGFSFSVWVKPAQLQGEAHLFSW
GDGAQGIVVGLDQNGAAFARVGQAATGRTQPLASQKWHHLAVAAEPGKRLAIYLDGREAASSAMPASMPAPAGDASIGGG
AQGGNFFAGEMDEVTLASVARSASWFAAAAGSQGQEGKLVSLAQEEAGGKGEADLTIHLMKVIAKSITLDGWAIIGLCTF
MLFLAAGVFVYKFLALQKIVKGNEMFLESFGELHDPLALEDTDDDLKHSSMYRIYQAGKIEIERWLARQSADKEISSLSP
SALNIFRSSLDKANVKEKQNLSSWLIVMTLGISGGPFWGLLGTVWGVMNTFASLAESGEANLTAIAPGVASALACTLFGL
FVAIPALFAYSYLTNRMKNLNADTHVFIDEYAVKVEGVYGERA
>Mature_602_residues
STPERRSMMNSRMFGRFARVTLAAAALVMTVAAVRAEAWWDEKWQQRRKITINTTAQGAEVKEAVADAAVLVRLHTGNFS
FTTAKPDGSDVRFVSGDDKTPLKFHFEMYDAKKEIALAWVKVPQVAPNSGQNTIWVYYGNSGVQAAQDVGGTYDTPQALV
YHFSETQGAPQDSSSYKNHAKEFAGGLGAPALIGGGATFKGAERIVVPASPSLSFPKGFSFSVWVKPAQLQGEAHLFSWG
DGAQGIVVGLDQNGAAFARVGQAATGRTQPLASQKWHHLAVAAEPGKRLAIYLDGREAASSAMPASMPAPAGDASIGGGA
QGGNFFAGEMDEVTLASVARSASWFAAAAGSQGQEGKLVSLAQEEAGGKGEADLTIHLMKVIAKSITLDGWAIIGLCTFM
LFLAAGVFVYKFLALQKIVKGNEMFLESFGELHDPLALEDTDDDLKHSSMYRIYQAGKIEIERWLARQSADKEISSLSPS
ALNIFRSSLDKANVKEKQNLSSWLIVMTLGISGGPFWGLLGTVWGVMNTFASLAESGEANLTAIAPGVASALACTLFGLF
VAIPALFAYSYLTNRMKNLNADTHVFIDEYAVKVEGVYGERA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG5306

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=97, Percent_Identity=41.2371134020619, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789381, Length=62, Percent_Identity=46.7741935483871, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 64423; Mature: 64291

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPERRSMMNSRMFGRFARVTLAAAALVMTVAAVRAEAWWDEKWQQRRKITINTTAQGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
EVKEAVADAAVLVRLHTGNFSFTTAKPDGSDVRFVSGDDKTPLKFHFEMYDAKKEIALAW
HHHHHHHCEEEEEEEECCCEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCHHHEEEE
VKVPQVAPNSGQNTIWVYYGNSGVQAAQDVGGTYDTPQALVYHFSETQGAPQDSSSYKNH
EECCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCHHHHEEEHHCCCCCCCCHHHHHH
AKEFAGGLGAPALIGGGATFKGAERIVVPASPSLSFPKGFSFSVWVKPAQLQGEAHLFSW
HHHHHCCCCCCCEECCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEHHHCCCCEEEEEC
GDGAQGIVVGLDQNGAAFARVGQAATGRTQPLASQKWHHLAVAAEPGKRLAIYLDGREAA
CCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCHHH
SSAMPASMPAPAGDASIGGGAQGGNFFAGEMDEVTLASVARSASWFAAAAGSQGQEGKLV
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHEEECCCCCCCCCEE
SLAQEEAGGKGEADLTIHLMKVIAKSITLDGWAIIGLCTFMLFLAAGVFVYKFLALQKIV
EEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGNEMFLESFGELHDPLALEDTDDDLKHSSMYRIYQAGKIEIERWLARQSADKEISSLSP
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCH
SALNIFRSSLDKANVKEKQNLSSWLIVMTLGISGGPFWGLLGTVWGVMNTFASLAESGEA
HHHHHHHHHHHHCCCHHHHCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NLTAIAPGVASALACTLFGLFVAIPALFAYSYLTNRMKNLNADTHVFIDEYAVKVEGVYG
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCC
ERA
CCC
>Mature Secondary Structure 
STPERRSMMNSRMFGRFARVTLAAAALVMTVAAVRAEAWWDEKWQQRRKITINTTAQGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
EVKEAVADAAVLVRLHTGNFSFTTAKPDGSDVRFVSGDDKTPLKFHFEMYDAKKEIALAW
HHHHHHHCEEEEEEEECCCEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCHHHEEEE
VKVPQVAPNSGQNTIWVYYGNSGVQAAQDVGGTYDTPQALVYHFSETQGAPQDSSSYKNH
EECCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCHHHHEEEHHCCCCCCCCHHHHHH
AKEFAGGLGAPALIGGGATFKGAERIVVPASPSLSFPKGFSFSVWVKPAQLQGEAHLFSW
HHHHHCCCCCCCEECCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEHHHCCCCEEEEEC
GDGAQGIVVGLDQNGAAFARVGQAATGRTQPLASQKWHHLAVAAEPGKRLAIYLDGREAA
CCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCHHH
SSAMPASMPAPAGDASIGGGAQGGNFFAGEMDEVTLASVARSASWFAAAAGSQGQEGKLV
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHEEECCCCCCCCCEE
SLAQEEAGGKGEADLTIHLMKVIAKSITLDGWAIIGLCTFMLFLAAGVFVYKFLALQKIV
EEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGNEMFLESFGELHDPLALEDTDDDLKHSSMYRIYQAGKIEIERWLARQSADKEISSLSP
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCH
SALNIFRSSLDKANVKEKQNLSSWLIVMTLGISGGPFWGLLGTVWGVMNTFASLAESGEA
HHHHHHHHHHHHCCCHHHHCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NLTAIAPGVASALACTLFGLFVAIPALFAYSYLTNRMKNLNADTHVFIDEYAVKVEGVYG
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCC
ERA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]