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The map label for this gene is yciR [C]

Identifier: 78222207

GI number: 78222207

Start: 1094700

End: 1096919

Strand: Direct

Name: yciR [C]

Synonym: Gmet_0987

Alternate gene names: 78222207

Gene position: 1094700-1096919 (Clockwise)

Preceding gene: 78222206

Following gene: 78222210

Centisome position: 27.39

GC content: 59.23

Gene sequence:

>2220_bases
GTGGGCGTTTACTGTGTAATGGCCGGCGGTTTCTTCTATTTCAGCCGATTTGGCCTTTTTTTGTCACCATCGCAACACAT
ACTCCTTCTTGCCGCTCTTGCCGCGGTTGTTTGCTACAACCTGCTGCTTCAGTTTTCCCGCGACCGCCTTGCCCGTGGTT
TCCGCCTTCTCAATTTCCTCCAGATTATCCTCGACCTTGTCCTGGTGTCGGTGCTGATCCATACGAGCGGCGGAGCAGCC
AGCTGGTTCTGGCCCGCATACCTGTTCGTCACCATAGAGGCATCCTTCCTCATCGAAGATCGTCGTGAAGTCTGGCTCGT
GGGTGGACTTGGCGGCCTTCTCTACGGAGCGGTGCTGGTGCTCGAGCATTTGAACATCGTTCCCTATGTGCGGATGCCCT
TCGTGGGCTCCGAGCTCCACCACGATCATCTGTATCTGCTCCTGACCTGGCTCTGGGTTTCGCTGCTCAATGCTGCCATG
GCGGCCATAGCCTCTTATTTCATGACGGTTATCCGTCGGGAAACCGACGCGGTCCGTGAGGGGGAGGAGCGGCTCGCCAC
ATTCCTCGACACGGCCAATGACCTGATCCACAGTGTGACCCCGGATGGTCGGCTCCTCTATGTGAACGAAGCCTGGCAGC
GGACCCTTGGCTATTCGGCTGAAGAGGCGGACGCGGTTCCTTTCTTCGATATCCTCCATCCCGACAGCCGCGAGCAATGC
TGCGCCGAACTGCAGCGGGTTGTTTCCGGTGATGCCCTGAGCCCAATGGAGGCGGTTTTCACGGCGAAGGACGGCCGTTC
AGTCATCGTGGAGGGGAGCCTCTCCTGCGCTCACGGAGGGGACGAATCCTCGGTCATCTGGAGCATCTGCCGCGACATCA
CGGAACGGAAGCATGCCGAGGAGCAGCTCTATCGGCTCGCCCACCACGATACCCTCACGGGGCTGCCGAACCGGATTCTC
TTCATGGATCGGCTCCAGCAGGCCAAGGCCCTGGCGAACCGCTACCGTTACCAGGTTGCGGTCCTGTTCCTTGACCTCGA
CCGCTTCAAGATCATTAACGACACCCTCGGGCATCCCGTGGGGGATCACCTTTTGCAGCAGGTGGCCCACCGGATCGCGG
GATGCGTGCGGGAAGTCGATACCGTGGCGCGCATCGGCGGCGACGAGTTCACCATCATTCTCGTGAATGTCGACACCGTC
GAGGACGTAAAGAGAATGGGGCAGAAGATTCTGAAGACGCTCGCCGCCCCCTTCAATATCGACACCCATGAGCTTTTCGT
CACGGCGAGCATCGGCATCTCCCTCTTTCCCTCCGATGGCGATAACCTGGACCAACTGGTGAAGAAGGCCGATATCGCCA
TGTATTGCGTGAAAGGGGAGGGGAGGAATAACGTTCAGTTCTATTCTCCCCAGATGGACGCCAACGCCGACAAGCGGCTA
CTGCTGGAAACGAGCCTGCGCAAGGCCCTCGACAACAGGGAGTTCAGGGTCTACTACCAGCCAAAGGTTGACATCGTCTC
CAAGAGAATTACCGCCATGGAAGCACTGATACGATGGGATCACCCAATTCTGGGGCTCGTTTCGCCCGGGGAGTTCATTC
CCCTGGCCGAAGAGACGGGACTCATCATCCCGATAGGTGAGTGGGTGCTCCGGGCCGCCTGCTTCCAGAACTGCGAGTGG
GTCAGGCAGGGAATCCCCCCCATGCGGGTGGCGGTGAATCTCTCCGGCTATCAGTTCCAGCAGAAGAACCTTCTGGAAAC
GATCCGGGGAATCCTGGACGAAACCGGGCTTACCGCGGATCTCCTGGAGCTTGAGATCACCGAGAGCGTCATCATGCAGA
ACCCGGACTTCGCCGTGTCGGTGCTCAACCAGTTGAGGGATCTCGGGGTCCACATCTCCATCGACGATTTCGGCATCGGC
TATTCTTCCCTGGCGCACCTGAAGCGGTTCTCGGTCAATACGCTCAAGATCGACAAGTCATTCGTGCGGGATGTGGAGAT
CAACTCGGCCGACGCCGCCATTGCCACGGCCATCATCGCCATGGGGAACAGTCTCAACCTGAAGGTCATCGCCGAGGGGG
TCGAGACGGAGGGGCAGCTATCGTTTCTCTCCGACAACAAGTGCGACGAGGTGCAGGGATACCTCTTCAGCACCCCGATG
CCGCCGGAGAAGGTCGCCGAGTTCATGCGGGAGCATGGGAGATCGGCCGGAAGGGGGTAG

Upstream 100 bases:

>100_bases
GGCTTCGGATAAACTGGAATTAAAGAAAACACAACGGTTGGAAGAGGCGAAGTCCCGCACTCACATCGTTGTCAGAACGC
GCTGGATCCTTCTCTCGTTT

Downstream 100 bases:

>100_bases
GATCAGGCGGAGGAGCGTTCGCGGAAGCGGAGATAGTCGTCGAGAATCCTGCGGTGGTCGAAGCAGAGTTCTGAGGGGAG
ATCGTTTAAGGGAAAGACCG

Product: diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MGVYCVMAGGFFYFSRFGLFLSPSQHILLLAALAAVVCYNLLLQFSRDRLARGFRLLNFLQIILDLVLVSVLIHTSGGAA
SWFWPAYLFVTIEASFLIEDRREVWLVGGLGGLLYGAVLVLEHLNIVPYVRMPFVGSELHHDHLYLLLTWLWVSLLNAAM
AAIASYFMTVIRRETDAVREGEERLATFLDTANDLIHSVTPDGRLLYVNEAWQRTLGYSAEEADAVPFFDILHPDSREQC
CAELQRVVSGDALSPMEAVFTAKDGRSVIVEGSLSCAHGGDESSVIWSICRDITERKHAEEQLYRLAHHDTLTGLPNRIL
FMDRLQQAKALANRYRYQVAVLFLDLDRFKIINDTLGHPVGDHLLQQVAHRIAGCVREVDTVARIGGDEFTIILVNVDTV
EDVKRMGQKILKTLAAPFNIDTHELFVTASIGISLFPSDGDNLDQLVKKADIAMYCVKGEGRNNVQFYSPQMDANADKRL
LLETSLRKALDNREFRVYYQPKVDIVSKRITAMEALIRWDHPILGLVSPGEFIPLAEETGLIIPIGEWVLRAACFQNCEW
VRQGIPPMRVAVNLSGYQFQQKNLLETIRGILDETGLTADLLELEITESVIMQNPDFAVSVLNQLRDLGVHISIDDFGIG
YSSLAHLKRFSVNTLKIDKSFVRDVEINSADAAIATAIIAMGNSLNLKVIAEGVETEGQLSFLSDNKCDEVQGYLFSTPM
PPEKVAEFMREHGRSAGRG

Sequences:

>Translated_739_residues
MGVYCVMAGGFFYFSRFGLFLSPSQHILLLAALAAVVCYNLLLQFSRDRLARGFRLLNFLQIILDLVLVSVLIHTSGGAA
SWFWPAYLFVTIEASFLIEDRREVWLVGGLGGLLYGAVLVLEHLNIVPYVRMPFVGSELHHDHLYLLLTWLWVSLLNAAM
AAIASYFMTVIRRETDAVREGEERLATFLDTANDLIHSVTPDGRLLYVNEAWQRTLGYSAEEADAVPFFDILHPDSREQC
CAELQRVVSGDALSPMEAVFTAKDGRSVIVEGSLSCAHGGDESSVIWSICRDITERKHAEEQLYRLAHHDTLTGLPNRIL
FMDRLQQAKALANRYRYQVAVLFLDLDRFKIINDTLGHPVGDHLLQQVAHRIAGCVREVDTVARIGGDEFTIILVNVDTV
EDVKRMGQKILKTLAAPFNIDTHELFVTASIGISLFPSDGDNLDQLVKKADIAMYCVKGEGRNNVQFYSPQMDANADKRL
LLETSLRKALDNREFRVYYQPKVDIVSKRITAMEALIRWDHPILGLVSPGEFIPLAEETGLIIPIGEWVLRAACFQNCEW
VRQGIPPMRVAVNLSGYQFQQKNLLETIRGILDETGLTADLLELEITESVIMQNPDFAVSVLNQLRDLGVHISIDDFGIG
YSSLAHLKRFSVNTLKIDKSFVRDVEINSADAAIATAIIAMGNSLNLKVIAEGVETEGQLSFLSDNKCDEVQGYLFSTPM
PPEKVAEFMREHGRSAGRG
>Mature_738_residues
GVYCVMAGGFFYFSRFGLFLSPSQHILLLAALAAVVCYNLLLQFSRDRLARGFRLLNFLQIILDLVLVSVLIHTSGGAAS
WFWPAYLFVTIEASFLIEDRREVWLVGGLGGLLYGAVLVLEHLNIVPYVRMPFVGSELHHDHLYLLLTWLWVSLLNAAMA
AIASYFMTVIRRETDAVREGEERLATFLDTANDLIHSVTPDGRLLYVNEAWQRTLGYSAEEADAVPFFDILHPDSREQCC
AELQRVVSGDALSPMEAVFTAKDGRSVIVEGSLSCAHGGDESSVIWSICRDITERKHAEEQLYRLAHHDTLTGLPNRILF
MDRLQQAKALANRYRYQVAVLFLDLDRFKIINDTLGHPVGDHLLQQVAHRIAGCVREVDTVARIGGDEFTIILVNVDTVE
DVKRMGQKILKTLAAPFNIDTHELFVTASIGISLFPSDGDNLDQLVKKADIAMYCVKGEGRNNVQFYSPQMDANADKRLL
LETSLRKALDNREFRVYYQPKVDIVSKRITAMEALIRWDHPILGLVSPGEFIPLAEETGLIIPIGEWVLRAACFQNCEWV
RQGIPPMRVAVNLSGYQFQQKNLLETIRGILDETGLTADLLELEITESVIMQNPDFAVSVLNQLRDLGVHISIDDFGIGY
SSLAHLKRFSVNTLKIDKSFVRDVEINSADAAIATAIIAMGNSLNLKVIAEGVETEGQLSFLSDNKCDEVQGYLFSTPMP
PEKVAEFMREHGRSAGRG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=446, Percent_Identity=39.237668161435, Blast_Score=336, Evalue=3e-93,
Organism=Escherichia coli, GI87081921, Length=435, Percent_Identity=34.7126436781609, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI226510982, Length=431, Percent_Identity=31.322505800464, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1790496, Length=256, Percent_Identity=34.765625, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI87081743, Length=247, Percent_Identity=33.1983805668016, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1788381, Length=586, Percent_Identity=26.7918088737201, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788502, Length=245, Percent_Identity=30.6122448979592, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1787055, Length=454, Percent_Identity=26.8722466960352, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI87081980, Length=251, Percent_Identity=32.2709163346614, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI87081845, Length=249, Percent_Identity=31.3253012048193, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1786507, Length=264, Percent_Identity=28.4090909090909, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87082096, Length=438, Percent_Identity=25.3424657534247, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788849, Length=249, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI87081881, Length=190, Percent_Identity=37.3684210526316, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=35.9756097560976, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=34.9397590361446, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=31.1377245508982, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082007, Length=184, Percent_Identity=31.5217391304348, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=36.5853658536585, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=35.2941176470588, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=27.4725274725275, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=168, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=105, Percent_Identity=37.1428571428571, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787410, Length=222, Percent_Identity=25.6756756756757, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=27.1084337349398, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 82596; Mature: 82465

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVYCVMAGGFFYFSRFGLFLSPSQHILLLAALAAVVCYNLLLQFSRDRLARGFRLLNFL
CCEEEEEECHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIILDLVLVSVLIHTSGGAASWFWPAYLFVTIEASFLIEDRREVWLVGGLGGLLYGAVLV
HHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEEEHHHEEECCCCEEEEECHHHHHHHHHHH
LEHLNIVPYVRMPFVGSELHHDHLYLLLTWLWVSLLNAAMAAIASYFMTVIRRETDAVRE
HHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEERLATFLDTANDLIHSVTPDGRLLYVNEAWQRTLGYSAEEADAVPFFDILHPDSREQC
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCCCCCCCCEEECCCCCCHHHH
CAELQRVVSGDALSPMEAVFTAKDGRSVIVEGSLSCAHGGDESSVIWSICRDITERKHAE
HHHHHHHHCCCCCCCHHHHEECCCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHH
EQLYRLAHHDTLTGLPNRILFMDRLQQAKALANRYRYQVAVLFLDLDRFKIINDTLGHPV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHCCCCH
GDHLLQQVAHRIAGCVREVDTVARIGGDEFTIILVNVDTVEDVKRMGQKILKTLAAPFNI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCC
DTHELFVTASIGISLFPSDGDNLDQLVKKADIAMYCVKGEGRNNVQFYSPQMDANADKRL
CCCEEEEEEECCEEEECCCCCCHHHHHHHCCEEEEEEECCCCCCCEEECCCCCCCCCHHH
LLETSLRKALDNREFRVYYQPKVDIVSKRITAMEALIRWDHPILGLVSPGEFIPLAEETG
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCC
LIIPIGEWVLRAACFQNCEWVRQGIPPMRVAVNLSGYQFQQKNLLETIRGILDETGLTAD
EEEEHHHHHHHHHHHHCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHH
LLELEITESVIMQNPDFAVSVLNQLRDLGVHISIDDFGIGYSSLAHLKRFSVNTLKIDKS
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEECHH
FVRDVEINSADAAIATAIIAMGNSLNLKVIAEGVETEGQLSFLSDNKCDEVQGYLFSTPM
HHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCHHHCCEEECCCC
PPEKVAEFMREHGRSAGRG
CHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GVYCVMAGGFFYFSRFGLFLSPSQHILLLAALAAVVCYNLLLQFSRDRLARGFRLLNFL
CEEEEEECHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIILDLVLVSVLIHTSGGAASWFWPAYLFVTIEASFLIEDRREVWLVGGLGGLLYGAVLV
HHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEEEHHHEEECCCCEEEEECHHHHHHHHHHH
LEHLNIVPYVRMPFVGSELHHDHLYLLLTWLWVSLLNAAMAAIASYFMTVIRRETDAVRE
HHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEERLATFLDTANDLIHSVTPDGRLLYVNEAWQRTLGYSAEEADAVPFFDILHPDSREQC
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCCCCCCCCEEECCCCCCHHHH
CAELQRVVSGDALSPMEAVFTAKDGRSVIVEGSLSCAHGGDESSVIWSICRDITERKHAE
HHHHHHHHCCCCCCCHHHHEECCCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHH
EQLYRLAHHDTLTGLPNRILFMDRLQQAKALANRYRYQVAVLFLDLDRFKIINDTLGHPV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHCCCCH
GDHLLQQVAHRIAGCVREVDTVARIGGDEFTIILVNVDTVEDVKRMGQKILKTLAAPFNI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCC
DTHELFVTASIGISLFPSDGDNLDQLVKKADIAMYCVKGEGRNNVQFYSPQMDANADKRL
CCCEEEEEEECCEEEECCCCCCHHHHHHHCCEEEEEEECCCCCCCEEECCCCCCCCCHHH
LLETSLRKALDNREFRVYYQPKVDIVSKRITAMEALIRWDHPILGLVSPGEFIPLAEETG
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCC
LIIPIGEWVLRAACFQNCEWVRQGIPPMRVAVNLSGYQFQQKNLLETIRGILDETGLTAD
EEEEHHHHHHHHHHHHCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHH
LLELEITESVIMQNPDFAVSVLNQLRDLGVHISIDDFGIGYSSLAHLKRFSVNTLKIDKS
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEECHH
FVRDVEINSADAAIATAIIAMGNSLNLKVIAEGVETEGQLSFLSDNKCDEVQGYLFSTPM
HHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCHHHCCEEECCCC
PPEKVAEFMREHGRSAGRG
CHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]