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The map label for this gene is glmM [H]

Identifier: 78222210

GI number: 78222210

Start: 1098034

End: 1099452

Strand: Direct

Name: glmM [H]

Synonym: Gmet_0990

Alternate gene names: 78222210

Gene position: 1098034-1099452 (Clockwise)

Preceding gene: 78222207

Following gene: 78222211

Centisome position: 27.47

GC content: 62.58

Gene sequence:

>1419_bases
ATGCATCGAATCGCTTTCGGCACGTCGGGTTGGCGCGGCATCCTCTGCGAGGATTTCACCTTCGAGAATGTTAAGGTAGT
GACCCAGGCCATTGCCGATCACGTGACGTCTATCGGCGAGAAGGAGAAGGGGATCATCGTCGCCTACGATACCCGTTTCA
TGGGGGAGCGTTTTGCCAAGGAAACCGCCCGGGTCCTGGCCGGCGCCGGCATCAAGGCCTATGTCTGCAAGCGCGACACG
CCGACCCCGGTGGTCTCCCACGAGATTCTGCGGCGCAAGGCTGCCGGAGCCATCAATTTTACCGCCAGCCACAATCCCCC
CGAGTACAACGGTATCAAGTTTTCTCCCTCTTGGGCCGGCCCCGCTCTCCCCGAGACCACCAAGGACATCGAGCGGCGGG
CCAACGAGATGCTGGGCGAGGTCTGCTACCGGGAAGTGGCCCTGGACGAGGCGGCCCGCGCCGGGCTCGTGGAGGAGATC
GACCCGCGGGAGACCTATCTGGCAGATATTGAGACGAAGGTCGACTTCACCGCCATCGCCTCCCTCGGGACCATCGCCGT
GAACGTTCTCTACGGCACCGCCCGGGGCTATCTGGACGAGCCCCTCATGAAGCACGGGGCGAAGATCAAAACCCTCAATA
TGCATCCCGACCCCTACTTTGGTGGTTTTCCCCCCGAGCCCTCCGAGAAATACATTCAGGACTTCATCGGGTTGGTAAAA
AGTGACCCGGCGGTGAAGCTGGGGATTGCCACCGACGGCGACGCTGACCGCTTCGGCATCGTTGATGCTGACGGTTCCTT
TATCGAGCCCAACTACATCATTGCGCTGCTCTTCGACTACCTGGTGCGGGTCCGGAAGATGACCGGCGCCGTTGCCCGCA
GCGTGGCCACTTCGCACCTGATCGACGCCGTGGCGAAGAAGCACGGCATCGAGGTAATCGAGACGCCGGTGGGCTTCAAG
TACGTGGGCGAGCTGATCAGCCAGGACCGCATCATCATCGGCGGCGAGGAGAGCGCCGGTCTTTCCATCAAAGGGCACGT
GCCGGAGAAGGACGGCATCCTTGCCTGCTTCCTTGTGGCTGAGATGGTTGCCCGGGAGGGGCTGTCGGTGAAGGCCCTGC
TGGAGCGACTCTACGGCGAGGTGGGGAGATTCTTGACGAAACGGGAGAACATTACCCTCTCGCCGGTCCTGGAAGCCGGG
TATGCCGACAAGCAGCGGCAGGCCCCGGCGGAGTTTGCCGGCCTGAAGGTGAAAGACATGGTGACCGTGGACGGGAGCAA
GTTCATCCTGGAGGACGGCAGCTGGCTCCTGTTCCGCAAATCGGGGACCGAGCCGGTGGTCCGGCTCTACGGCGAGGCGT
CCAGCGAGGAGAAACTGGCTGCGGTCATGGCGGCGGGGAAGGCGTTCATTCTGGGGTGA

Upstream 100 bases:

>100_bases
CTCGGCAGGGTTGACTCGCCACGGGGTATGTATTAGGCTTTCACTGCATGAAAAATCGGGTCTCCGCCCCATGCGGAGCC
ATTTCCCCAAGGGAGGGACA

Downstream 100 bases:

>100_bases
GGCACTGCAGGGAATAACACGGAGAGACGGAGCGCACGGAGAAAGCCAAGGCAGACTTCAAAATTTGTCGTAAGAATAAC
TCCTTGTTGCTTTCTACCGA

Product: phosphoglucomutase/phosphomannomutase alpha/beta/subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MHRIAFGTSGWRGILCEDFTFENVKVVTQAIADHVTSIGEKEKGIIVAYDTRFMGERFAKETARVLAGAGIKAYVCKRDT
PTPVVSHEILRRKAAGAINFTASHNPPEYNGIKFSPSWAGPALPETTKDIERRANEMLGEVCYREVALDEAARAGLVEEI
DPRETYLADIETKVDFTAIASLGTIAVNVLYGTARGYLDEPLMKHGAKIKTLNMHPDPYFGGFPPEPSEKYIQDFIGLVK
SDPAVKLGIATDGDADRFGIVDADGSFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHLIDAVAKKHGIEVIETPVGFK
YVGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVAEMVAREGLSVKALLERLYGEVGRFLTKRENITLSPVLEAG
YADKQRQAPAEFAGLKVKDMVTVDGSKFILEDGSWLLFRKSGTEPVVRLYGEASSEEKLAAVMAAGKAFILG

Sequences:

>Translated_472_residues
MHRIAFGTSGWRGILCEDFTFENVKVVTQAIADHVTSIGEKEKGIIVAYDTRFMGERFAKETARVLAGAGIKAYVCKRDT
PTPVVSHEILRRKAAGAINFTASHNPPEYNGIKFSPSWAGPALPETTKDIERRANEMLGEVCYREVALDEAARAGLVEEI
DPRETYLADIETKVDFTAIASLGTIAVNVLYGTARGYLDEPLMKHGAKIKTLNMHPDPYFGGFPPEPSEKYIQDFIGLVK
SDPAVKLGIATDGDADRFGIVDADGSFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHLIDAVAKKHGIEVIETPVGFK
YVGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVAEMVAREGLSVKALLERLYGEVGRFLTKRENITLSPVLEAG
YADKQRQAPAEFAGLKVKDMVTVDGSKFILEDGSWLLFRKSGTEPVVRLYGEASSEEKLAAVMAAGKAFILG
>Mature_472_residues
MHRIAFGTSGWRGILCEDFTFENVKVVTQAIADHVTSIGEKEKGIIVAYDTRFMGERFAKETARVLAGAGIKAYVCKRDT
PTPVVSHEILRRKAAGAINFTASHNPPEYNGIKFSPSWAGPALPETTKDIERRANEMLGEVCYREVALDEAARAGLVEEI
DPRETYLADIETKVDFTAIASLGTIAVNVLYGTARGYLDEPLMKHGAKIKTLNMHPDPYFGGFPPEPSEKYIQDFIGLVK
SDPAVKLGIATDGDADRFGIVDADGSFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHLIDAVAKKHGIEVIETPVGFK
YVGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVAEMVAREGLSVKALLERLYGEVGRFLTKRENITLSPVLEAG
YADKQRQAPAEFAGLKVKDMVTVDGSKFILEDGSWLLFRKSGTEPVVRLYGEASSEEKLAAVMAAGKAFILG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=480, Percent_Identity=29.5833333333333, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI290463102, Length=506, Percent_Identity=28.4584980237154, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI133922562, Length=468, Percent_Identity=27.991452991453, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI290463104, Length=316, Percent_Identity=28.7974683544304, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI1786904, Length=493, Percent_Identity=29.8174442190669, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1788361, Length=429, Percent_Identity=27.039627039627, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789566, Length=472, Percent_Identity=26.6949152542373, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17535441, Length=509, Percent_Identity=30.0589390962672, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71993870, Length=515, Percent_Identity=24.6601941747573, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71993878, Length=115, Percent_Identity=33.0434782608696, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323752, Length=516, Percent_Identity=26.937984496124, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322722, Length=432, Percent_Identity=28.0092592592593, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17864244, Length=527, Percent_Identity=28.6527514231499, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI20129809, Length=528, Percent_Identity=25, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24651977, Length=426, Percent_Identity=25.5868544600939, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 51406; Mature: 51406

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRIAFGTSGWRGILCEDFTFENVKVVTQAIADHVTSIGEKEKGIIVAYDTRFMGERFAK
CCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
ETARVLAGAGIKAYVCKRDTPTPVVSHEILRRKAAGAINFTASHNPPEYNGIKFSPSWAG
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCCC
PALPETTKDIERRANEMLGEVCYREVALDEAARAGLVEEIDPRETYLADIETKVDFTAIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHCCCHHHHHH
SLGTIAVNVLYGTARGYLDEPLMKHGAKIKTLNMHPDPYFGGFPPEPSEKYIQDFIGLVK
HHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHC
SDPAVKLGIATDGDADRFGIVDADGSFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHL
CCCCEEEEEECCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAVAKKHGIEVIETPVGFKYVGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVA
HHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHH
EMVAREGLSVKALLERLYGEVGRFLTKRENITLSPVLEAGYADKQRQAPAEFAGLKVKDM
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEECHHHHCCCCCHHHCCCHHHHCCEEEEE
VTVDGSKFILEDGSWLLFRKSGTEPVVRLYGEASSEEKLAAVMAAGKAFILG
EEECCCEEEEECCCEEEEECCCCCHHHEEECCCCCHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MHRIAFGTSGWRGILCEDFTFENVKVVTQAIADHVTSIGEKEKGIIVAYDTRFMGERFAK
CCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
ETARVLAGAGIKAYVCKRDTPTPVVSHEILRRKAAGAINFTASHNPPEYNGIKFSPSWAG
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCCC
PALPETTKDIERRANEMLGEVCYREVALDEAARAGLVEEIDPRETYLADIETKVDFTAIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHCCCHHHHHH
SLGTIAVNVLYGTARGYLDEPLMKHGAKIKTLNMHPDPYFGGFPPEPSEKYIQDFIGLVK
HHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHC
SDPAVKLGIATDGDADRFGIVDADGSFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHL
CCCCEEEEEECCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAVAKKHGIEVIETPVGFKYVGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVA
HHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHH
EMVAREGLSVKALLERLYGEVGRFLTKRENITLSPVLEAGYADKQRQAPAEFAGLKVKDM
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEECHHHHCCCCCHHHCCCHHHHCCEEEEE
VTVDGSKFILEDGSWLLFRKSGTEPVVRLYGEASSEEKLAAVMAAGKAFILG
EEECCCEEEEECCCEEEEECCCCCHHHEEECCCCCHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA